Next Generation Therapies (NGT)

Next Generation Therapies (NGT)

The Next Generation Therapies (NGT) research program discovers and characterizes novel agents and pathways; translates these discoveries through innovative, preclinical proof-of-principle studies; and provides more effective cancer therapies to our patients.

Capabilities

Next Generation Therapies (NGT) program members have expertise in the following areas:

  • Novel drug development platforms
  • Immunotherapy
  • Targeting molecular pathways of resistance
  • Migration
  • Apoptosis or cell death
  • Cell cycle inhibition and epigenetic modifiers
  • Autophagy
  • Inflammation
  • Membrane disrupters
  • Agents that modify cholesterol/lipid peroxidation
  • Various imaging modalities

Collaborations

Program members also collaborate with colleagues in biomedical engineering at Penn State University Park, as well as with Cancer Control research program members regarding the role of exercise in treatment outcomes for cancer patients. Additional collaborations involve work with the Mechanisms of Carcinogenesis research program on the identification of genomic markers in metastatic melanoma as potential markers of response.

Contact Us

Deborah Kelly, PhD: debkelly@psu.edu or 814-865-8242

Penn State Cancer Institute members who are part of the Next Generation Therapies research program are listed here.
James Hansell Adair, PhD James Hansell Adair, PhD View Researcher Profile
Reka Z. Albert, PhD Reka Z. Albert, PhD View Researcher Profile
Marco Archetti Marco Archetti View Researcher Profile
Dawit Aregawi, MD Dawit Aregawi, MD View Researcher Profile
Anilchandra Attaluri Anilchandra Attaluri View Researcher Profile
Chandra Belani, MD Chandra Belani, MD View Researcher Profile
James Broach, PhD James Broach, PhD View Researcher Profile
Valerie Brown, MD, PhD Valerie Brown, MD, PhD View Researcher Profile
Keith Cheng, MD, PhD Keith Cheng, MD, PhD View Researcher Profile
Karen Choi, MD Karen Choi, MD View Researcher Profile
Gary Clawson, MS, PhD, MD Gary Clawson, MS, PhD, MD View Researcher Profile
David Claxton, MD David Claxton, MD View Researcher Profile
James Connor, MS, PhD James Connor, MS, PhD View Researcher Profile
David Degraff, PhD David Degraff, PhD View Researcher Profile
Dhimant Desai, PhD Dhimant Desai, PhD View Researcher Profile
Nikolay Dokholyan, PhD, MS Nikolay Dokholyan, PhD, MS View Researcher Profile
Cheng Dong, PhD Cheng Dong, PhD View Researcher Profile
Sinisa Dovat, PhD, MD Sinisa Dovat, PhD, MD View Researcher Profile
Joseph Drabick, MD Joseph Drabick, MD View Researcher Profile
John Flanagan, PhD John Flanagan, PhD View Researcher Profile
Edward Fox, MD Edward Fox, MD View Researcher Profile
Zhonghua Gao, PhD Zhonghua Gao, PhD View Researcher Profile
Chandrika Gowda, MD Chandrika Gowda, MD View Researcher Profile
Sergei Grigoryev, MS, PhD Sergei Grigoryev, MS, PhD View Researcher Profile
Edward Gunther, MD Edward Gunther, MD View Researcher Profile
Nadine Hempel, PhD Nadine Hempel, PhD View Researcher Profile
Diane Hershock, MD, PhD Diane Hershock, MD, PhD View Researcher Profile
William Evan Higgins, PhD William Evan Higgins, PhD View Researcher Profile
Raymond Hohl, MD, PhD Raymond Hohl, MD, PhD View Researcher Profile
Sheldon Holder, PhD, MD Sheldon Holder, PhD, MD View Researcher Profile
Monika Joshi, MD, MRCP Monika Joshi, MD, MRCP View Researcher Profile
Deb Kelly Deb Kelly View Researcher Profile
Sri-Rajasekhar Kothapalli, PhD Sri-Rajasekhar Kothapalli, PhD View Researcher Profile
Sang Lee, MS, PhD Sang Lee, MS, PhD View Researcher Profile
Jiangang (Jason) Liao, PhD Jiangang (Jason) Liao, PhD View Researcher Profile
John C. Liechty John C. Liechty View Researcher Profile
Zhenqiu Liu, PhD Zhenqiu Liu, PhD View Researcher Profile
Junxuan Lu, PhD Junxuan Lu, PhD View Researcher Profile
Patrick Chi-Chung Ma, MD, MSc Patrick Chi-Chung Ma, MD, MSc View Researcher Profile
Heath Mackley, MD Heath Mackley, MD View Researcher Profile
Gail Matters, MS, PhD Gail Matters, MS, PhD View Researcher Profile
Lisa McGregor, MD, PhD Lisa McGregor, MD, PhD View Researcher Profile
Patricia McLaughlin, MS, DEd Patricia McLaughlin, MS, DEd View Researcher Profile
Barbara Miller, MD Barbara Miller, MD View Researcher Profile
Kentaro Minagawa, MD, PhD Kentaro Minagawa, MD, PhD View Researcher Profile
Shin Mineishi, MD Shin Mineishi, MD View Researcher Profile
George-Lucian Moldovan, PhD George-Lucian Moldovan, PhD View Researcher Profile
Matthew Moyer, MS, MD Matthew Moyer, MS, MD View Researcher Profile
Kathleen Mulder, PhD Kathleen Mulder, PhD View Researcher Profile
Claudia Nicolae, PhD Claudia Nicolae, PhD View Researcher Profile
Sean O'Donnell, MD Sean O'Donnell, MD View Researcher Profile
Colette R. Pameijer, MD Colette R. Pameijer, MD View Researcher Profile
Rebecca Phaeton, MD Rebecca Phaeton, MD View Researcher Profile
Dino Ravnic, DO, MPH Dino Ravnic, DO, MPH View Researcher Profile
Andrew Fraser Read, PhD Andrew Fraser Read, PhD View Researcher Profile
Michael F. Reed, MD Michael F. Reed, MD View Researcher Profile
Elias Rizk, MD, MSc Elias Rizk, MD, MSc View Researcher Profile
Gavin Robertson, PhD Gavin Robertson, PhD View Researcher Profile
Jennifer Rosenberg, MD Jennifer Rosenberg, MD View Researcher Profile
Witold Rybka, MD, FRCPC Witold Rybka, MD, FRCPC View Researcher Profile
Lorraine C. Santy, PhD Lorraine C. Santy, PhD View Researcher Profile
Arun Sharma, PhD Arun Sharma, PhD View Researcher Profile
Arati Sharma, PhD Arati Sharma, PhD View Researcher Profile
Hiroko Shike, MD, MS Hiroko Shike, MD, MS View Researcher Profile
Chunhua Song, MD, MS, PhD Chunhua Song, MD, MS, PhD View Researcher Profile
Douglas Stairs, PhD Douglas Stairs, PhD View Researcher Profile
Yoshinori Takahashi, MS, PhD Yoshinori Takahashi, MS, PhD View Researcher Profile
Matthew D. Taylor, MD Matthew D. Taylor, MD View Researcher Profile
Cristina Truica, MD Cristina Truica, MD View Researcher Profile
Henry Wagner Jr., MD Henry Wagner Jr., MD View Researcher Profile
Hong-Gang Wang, PhD Hong-Gang Wang, PhD View Researcher Profile
David Waning, PhD David Waning, PhD View Researcher Profile
Pak Kin Wong, PhD Pak Kin Wong, PhD View Researcher Profile
Jian Yang, PhD Jian Yang, PhD View Researcher Profile
Nelson Shu-Sang Yee, MD, PhD, RPh Nelson Shu-Sang Yee, MD, PhD, RPh View Researcher Profile
Jong Yun, PhD Jong Yun, PhD View Researcher Profile
Ian Zagon, MS, PhD Ian Zagon, MS, PhD View Researcher Profile
Shouhao Zhou, PhD Shouhao Zhou, PhD View Researcher Profile

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