Monali Vasekar, MD - Penn State Cancer Institute
Researcher Profile
Monali Vasekar, MD
Associate Professor, Department of Medicine
Assistant Professor, Department of Medicine
Division of Hematology and Oncology
Assistant Professor, Department of Medicine
Division of Hematology and Oncology
Scientific Program:Next-Generation Therapies
Clinical Trials
CCTG MA.39:Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Breast Cancer
Pilot study to evaluate if contrast-enhanced ultrasound (CEUS) can predict treatment response in triple negative breast cancer (TNBC) patients receiving combined chemotherapy and Immune Checkpoint Inhibitors (ICI).
A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/or Axillary Lymph Nodes at Surgical Resection Following Neoadjuvant Systemic Therapy(TROPION-Breast03)
NRG-BR009: A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression plus Endocrine Therapy in Premenopausal Patients with pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score (OFSET)
A012103: OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy with Checkpoint Inhibitor Therapy
NRG-BR008: A Phase III Randomized Trial of Radiotherapy Optimization for Low-Risk HER2-Positive Breast Cancer (HERO)
S1501, Prospective Observational Cohort Study of Patients with Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
NRG-BR007: A Phase III Clinical Trial Evaluating Deescalation of Breast Radiation for Conservative Treatment of Stage I, Hormone sensitive, HER2- Negative Oncotype recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
BINGO: Bridging Knowledge, Increasing Awareness - Empowering the Black Community through Educational Gamification on Cancer Screenings and Clinical Trial Diversity
A Phase 1b/2 Study Assessing the Safety and Efficacy of Evexomostat (SDX-7320) in Combination with a PI3K Pathway Inhibitor plus Fulvestrant in Postmenopausal Women with Advanced Breast Cancer and PI3K Pathway Alterations Who Have Progressed on or Following Endocrine Therapy plus a CDK4/6 Inhibitor
An Open Label, Phase II Trial of Pre-operative Neratinib and Endocrine Therapy with Trastuzumab in Triple Positive Breast Cancers
APG-115 - A Phase Ib/II Study of APG-115 in Combination with Pembrolizumab in Patients with Unresectable or Metastatic Melanomas or Advanced Solid Tumors
A Phase II Study of Ribociclib and Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer (RaPhLRR Study) (HCRN-BRE20-468)
Shorter Anthracycline-Free Chemo Immunotherapy Adapted to Pathological Response in Early Triple Negative Breast Cancer (SCARLET), A Randomized Phase III Study
Phase 1, open label clinical trial to treat Stage IV cancer patients with multiple patient-specific mutated cell surface proteins with chimeric antibodies
Recent Publications
2024
Labe, S, Jones, G, Dailey, H, Bhasker, J, Kanwar, R, Crago, M, Fitzgerald, B, Mikhail, D, Hafiz, S, Kramer, C, Zhu, J & Vasekar, M 2025, 'D-CRSE: Diminishing chemotherapy-related side effects through patient education, a mixed-methods pilot study', Journal of Psychosocial Oncology, vol. 43, no. 1, pp. 1-15. https://doi.org/10.1080/07347332.2024.2345124
2023
Gordon, BR, Qiu, L, Doerksen, SE, Kanski, B, Lorenzo, A, Truica, CI, Vasekar, M, Wang, M, Winkels, RM, Abdullah, S & Schmitz, KH 2023, 'Addressing metastatic individuals everyday: Rationale and design of the nurse AMIE for Amazon Echo Show trial among metastatic breast cancer patients', Contemporary Clinical Trials Communications, vol. 32, 101058. https://doi.org/10.1016/j.conctc.2023.101058
Dailey, H, Labe, S, Jones, G, Bhasker, J, Kanwar, R, Hafiz, S, Crago, M, Fitzgerald, B, Mikhail, D, Zhu, J & Vasekar, M 2023, 'D-CRSE: Diminishing chemotherapy related side effects through patient education', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41, no. 16_suppl, e24148.
Julian, K & Vasekar, M 2023, 'Thoracic splenosis: an important consideration in oncology patients', BMJ case reports, vol. 16, no. 11, e257091. https://doi.org/10.1136/bcr-2023-257091
2022
Weng, X, Shen, C, Vasekar, M, Boltz, M, Joshi, M, Van Scoy, LJ & Wang, L 2023, 'Alzheimer's disease and related dementias is a risk factor for lower utilization of breast cancer screening and unstaged cancer diagnosis: Observational study from SEER-Medicare 2004–2016 data', Journal of Geriatric Oncology, vol. 14, no. 3, 101407. https://doi.org/10.1016/j.jgo.2022.11.006
2021
Nesterova, D, Zhu, J, Kramer, C, Vasekar, M, Truica, C, Joshi, A, Hayes, M, Kessler, J, Saunders, EFH, Drabick, JJ & Joshi, M 2022, 'Group-led creative writing and behavioural health in cancer: A randomised clinical trial', BMJ Supportive and Palliative Care, vol. 12, no. 1, pp. 91-98. https://doi.org/10.1136/bmjspcare-2020-002463
Mrowczynski, OD, Vasekar, M, Fox, E, Harbaugh, K, Aregawi, D, Pameijer, CR, Zaorsky, N, Payne, R & Rizk, E 2021, 'Spontaneous Hip Dislocation Complicating the Management of Malignant Peripheral Nerve Sheath Tumor Arising Within a Plexiform Neurofibroma', Cureus, vol. 13, no. 7, e16320. https://doi.org/10.7759/cureus.16320
2020
Stahl, K, Wong, W, Dodge, D, Brooks, A, McLaughlin, C, Olecki, E, Lewcun, J, Newport, K, Vasekar, M & Shen, C 2021, 'Benefits of Surgical Treatment of Stage IV Breast Cancer for Patients With Known Hormone Receptor and HER2 Status', Annals of Surgical Oncology, vol. 28, no. 5, pp. 2646-2658. https://doi.org/10.1245/s10434-020-09244-5
Poulson, J, Cai, A, Benson, J & Vasekar, M 2020, 'EBV-Induced Pancytopenia: An Unusual Presentation of EBV Causing Bone Marrow Suppression-A Case Report', Penn State Journal of Medicine. https://doi.org/10.26209/psjm61974
Pancholy, N, Walter, V, Drabick, J, Fox, EJ, Zaorsky, N & Vasekar, M 2020, 'Growth factor and its role in the treatment of patients with soft tissue extremity sarcoma receiving chemotherapy managed at an academic center: A retrospective study', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 38, no. 15_suppl, e23573.
Polimera, H, Moku, P, Abusharar, SP, Vasekar, M & Chintanaboina, J 2020, 'Metastasis of Ewing Sarcoma to the Pancreas: Case Report and Literature Review', Case Reports in Oncological Medicine, pp. 7075048. https://doi.org/10.1155/2020/7075048
Hendriksen, BS, Stahl, KA, Hollenbeak, CS, Taylor, MD, Vasekar, MK, Drabick, JJ, Conte, JV, Soleimani, B & Reed, MF 2021, 'Postoperative chemotherapy and radiation improve survival following cardiac sarcoma resection', Journal of Thoracic and Cardiovascular Surgery, vol. 161, no. 1, pp. 110-119.e4. https://doi.org/10.1016/j.jtcvs.2019.10.016
Yin, M, Grivas, P, Wang, QE, Mortazavi, A, Emamekhoo, H, Holder, SL, Drabick, JJ, Woo, MSA, Pal, S, Vasekar, M, Folefac, E, Clinton, SK, Monk, P & Joshi, M 2020, 'Prognostic Value of DNA Damage Response Genomic Alterations in Relapsed/Advanced Urothelial Cancer', Oncologist, vol. 25, no. 8, pp. 680-688. https://doi.org/10.1634/theoncologist.2019-0851
Vasekar, M, Agbese, E & Leslie, D 2020, 'The value of immunotherapy: Comparison of annual cost per patient receiving immunotherapy versus chemotherapy in patients with non-small cell lung cancer', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 38, no. 15_suppl, e19364.