Dino Ravnic, DO, MPH, MSc - Penn State Cancer Institute
Researcher Profile
Dino Ravnic, DO, MPH, MSc
Professor, Department of Surgery
Division of Plastic Surgery
Division of Plastic Surgery
Scientific Program:Next-Generation Therapies
Recent Publications
2026
Yeo, M, El-Mallah, JC, Horchler, SN, Waldron, O, Asgardoon, MH, Jikaria, NR, Dawes, J, Landmesser, M, Sun, M, Ozbolat, IT & Ravnic, DJ 2026, 'Coupling intraoperative bioprinting and surgical micropuncture for synergistic scaffold vascularization', Biomaterials, vol. 326, 123711. https://doi.org/10.1016/j.biomaterials.2025.123711
2025
El-Mallah, JC, Wen, C, Waldron, O, Jikaria, NR, Asgardoon, MH, Schlidt, K, Goldenberg, D, Horchler, S, Landmesser, ME, Park, JH, Hasegawa, U, Wang, Y & Ravnic, DJ 2025, 'Current Modalities in Soft-Tissue Reconstruction and Vascularized Adipose Engineering', Biomolecules, vol. 15, no. 6, 780. https://doi.org/10.3390/biom15060780
Wen, C, Park, JH, Jikaria, NR, Landmesser, ME, Dawes, J, Wu, CW, Ravnic, D & Wang, Y 2025, 'Enhanced safety and potency in local angiogenic growth factor delivery via aptamer functionalization of hydrogels', Journal of Controlled Release, vol. 387, 114251. https://doi.org/10.1016/j.jconrel.2025.114251
Dawes, JS, Abdelaal, M, Landmesser, ME, Asgardoon, MH, Waldron, OP, Park, JH, Jikaria, N & Ravnic, DJ 2025, 'Exosomes: the future of acellular nanotherapeutics in regenerative vascularization', Frontiers in Bioengineering and Biotechnology, vol. 13, 1607605. https://doi.org/10.3389/fbioe.2025.1607605
Yeingst, TJ, Helton, AM, Rawnaque, FS, Arrizabalaga, JH, Ravnic, DJ, Simon, JC & Hayes, DJ 2025, 'Focused Ultrasound-Mediated Release of Bone Morphogenetic Protein 2 from Hydrogels for Bone Regeneration', Gels, vol. 11, no. 2, 120. https://doi.org/10.3390/gels11020120
El-Mallah, JC, Ataie, Z, Horchler, SN, Landmesser, ME, Asgardoon, MH, Waldron, O, Jaberi, A, Kedzierski, A, Sun, M, Sheikhi, A & Ravnic, DJ 2025, 'Micropuncture and granular hydrogel scaffolds to surgically bioengineer a perfusable and stably patterned microvasculature', Angiogenesis, vol. 28, no. 4, 47. https://doi.org/10.1007/s10456-025-10003-x
Singh, H, Biswas, D, Park, JH, Landmesser, ME, Ravnic, DJ & Medina, SH 2025, 'Non-invasive ultrasonic debridement of implant biofilms via hydrogen-sulfide releasing peptide nanoemulsions', Biomaterials, vol. 321, 123337. https://doi.org/10.1016/j.biomaterials.2025.123337
Schlidt, K, Asgardoon, M, Febre-Alemañy, DA, El-Mallah, JC, Waldron, O, Dawes, J, Agrawal, S, Landmesser, ME & Ravnic, DJ 2025, 'Surgical Bioengineering of the Microvasculature and Challenges in Clinical Translation', Tissue Engineering - Part B: Reviews, vol. 31, no. 6, pp. 566-588. https://doi.org/10.1089/ten.teb.2024.0242
2024
Shan, D, Wang, D, Ma, Y, Liang, Z, Ravnic, DJ, Zhang, N & Yang, J 2025, 'Biodegradable Citrate-Based Polymers Enable 5D Monitoring of Implant Evolution', Advanced Functional Materials, vol. 35, no. 5, 2414400. https://doi.org/10.1002/adfm.202414400
Jaberi, A, Kedzierski, A, Kheirabadi, S, Tagay, Y, Ataie, Z, Zavari, S, Naghashnejad, M, Waldron, O, Adhikari, D, Lester, G, Gallagher, C, Borhan, A, Ravnic, D, Tabdanov, E & Sheikhi, A 2024, 'Engineering Microgel Packing to Tailor the Physical and Biological Properties of Gelatin Methacryloyl Granular Hydrogel Scaffolds', Advanced Healthcare Materials, vol. 13, no. 25, 2402489. https://doi.org/10.1002/adhm.202402489
Kang, Y, Yeo, M, Derman, ID, Ravnic, DJ, Singh, YP, Alioglu, MA, Wu, Y, Makkar, J, Driskell, RR & Ozbolat, IT 2024, 'Intraoperative bioprinting of human adipose-derived stem cells and extra-cellular matrix induces hair follicle-like downgrowths and adipose tissue formation during full-thickness craniomaxillofacial skin reconstruction', Bioactive Materials, vol. 33, pp. 114-128. https://doi.org/10.1016/j.bioactmat.2023.10.034
Celik, N, Koduru, SV, Ravnic, DJ, Ozbolat, IT & Hayes, DJ 2024, 'Posttranscriptional Modification to Modulate Progenitor Differentiation on Heterotypic Spheroids', Tissue Engineering - Part A, vol. 30, no. 17-18, pp. 536-549. https://doi.org/10.1089/ten.tea.2023.0279
Waldron, OP, El-Mallah, JC, Lochan, D, Wen, C, Landmesser, ME, Asgardoon, M, Dawes, J, Horchler, SN, Schlidt, K, Agrawal, S, Wang, Y & Ravnic, DJ 2024, 'Ushering in the era of regenerative surgery', Minerva Surgery, vol. 79, no. 2, pp. 166-182. https://doi.org/10.23736/S2724-5691.23.10113-4
2023
Ataie, Z, Horchler, S, Jaberi, A, Koduru, SV, El-Mallah, JC, Sun, M, Kheirabadi, S, Kedzierski, A, Risbud, A, Silva, ARAE, Ravnic, DJ & Sheikhi, A 2024, 'Accelerating Patterned Vascularization Using Granular Hydrogel Scaffolds and Surgical Micropuncture', Small, vol. 20, no. 8, 2307928. https://doi.org/10.1002/smll.202307928
Abune, L, Wen, C, Lee, K, Wang, X, Ravnic, D & Wang, Y 2024, 'Elastic Macroporous Matrix-Supported In Situ Formation of Injectable Extracellular Matrix-Like Hydrogel for Carrying Growth Factors and Living Cells', Macromolecular Bioscience, vol. 24, no. 3, 2300475. https://doi.org/10.1002/mabi.202300475
Greene, A, Zhang, Y, Asan, O, Clark, JB, Fell, B, Harter, K, Samson, T, Ravnic, D, Cilley, RE, Dillon, P, Mackay, D & Tsai, AY 2023, 'Successful application of the innovation process to a case of Floyd Type I tracheal agenesis', Surgery Open Science, vol. 11, pp. 73-76. https://doi.org/10.1016/j.sopen.2022.11.005
Horchler, SN, Hancock, PC, Sun, M, Liu, AT, Massand, S, El-Mallah, JC, Goldenberg, D, Waldron, O, Landmesser, ME, Agrawal, S, Koduru, SV & Ravnic, DJ 2024, 'Vascular persistence following precision micropuncture', Microcirculation, vol. 31, no. 1, e12835. https://doi.org/10.1111/micc.12835
2022
McLaughlin, C, Datta, P, Singh, YP, Lo, A, Horchler, S, Elcheva, IA, Ozbolat, IT, Ravnic, DJ & Koduru, SV 2022, 'Mesenchymal Stem Cell-Derived Extracellular Vesicles for Therapeutic Use and in Bioengineering Applications', Cells, no. 21, 3366. https://doi.org/10.3390/cells11213366
McLaughlin, C, Hughes, AJ, Parham, CS, Fritsche, M, Potochny, JD, Kunselman, A & Ravnic, DJ 2022, 'Smooth Versus Textured Tissue Expander Breast Reconstruction: Complications and Efficacy', Annals of plastic surgery, vol. 88, no. 3, pp. S288-S292. https://doi.org/10.1097/SAP.0000000000003193
Vidt, ME, Heitzenrater, J, Dodge, D, Potochny, J, Widders, K, Paulishak, M, Ravnic, D, Henry, CR, Green, M, Kass, R & Schmitz, KH 2022, 'The role of physical arm function and demographic disparities in breast cancer survivors’ ability to return to work', Supportive Care in Cancer, vol. 30, no. 12, pp. 10301-10310. https://doi.org/10.1007/s00520-022-07449-w