Researcher Profile

Researcher Profile

Dawit Aregawi, MD

Dawit Aregawi, MD

Assistant Professor, Department of Neurosurgery
Scientific Program:Next-Generation Therapies
Disease Teams:
Central Nervous System Cancer
dxa22@psu.edu

Research Interests

  • Therapeutics
  • Polycystic Ovary Syndrome
  • Diet
  • Metformin
  • Glioblastoma
  • Glioma
  • Mutation
  • Thrombophilia
  • Drug Therapy
  • Weights and Measures
  • Cholesterol
  • Insulin Resistance

Clinical Trials

A Phase 1b/2 study to assess the safety, tolerability and efficacy of BGB-290 in combination with radiation therapy and/or temozolomide in subjects with first-line or recurrent/refractory glioblastoma
Standard Chemotherapy versus Chemotherapy Chosen by Cancer Stem Cell Chemosensitivity Testing in the Management of Patients with Recurrent Glioblastoma Multiforme (GBM).
A phase III trial of marizomib in combination with standard temozolomide-based radiochemotherapy versus standard temozolomide-based radiochemotherapy alone in patients with newly diagnosed glioblastoma
3D Prediction of Patient‐specific Response using Ex vivo Interrogation of Live Cells from Tumors
Risk Factors for CIPN Following an Oxaliplatin-Containing Chemotherapy Regimen in Colorectal Cancer Patients

Recent Publications

2020

Yee, PP, Wei, Y, Kim, SY, Lu, T, Chih, SY, Lawson, C, Tang, M, Liu, Z, Anderson, B, Thamburaj, K, Young, MM, Aregawi, DG, Glantz, MJ, Zacharia, BE, Specht, CS, Wang, HG & Li, W 2020, 'Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression', Nature communications, vol. 11, no. 1, 5424. https://doi.org/10.1038/s41467-020-19193-y

2019

Payne, R, Mrowczynski, OD, Slagle-Webb, B, Bourcier, A, Mau, C, Aregawi, D, Madhankumar, AB, Lee, SY, Harbaugh, K, Connor, J & Rizk, EB 2019, 'MLN8237 treatment in an orthoxenograft murine model for malignant peripheral nerve sheath tumors', Journal of neurosurgery, vol. 130, no. 2, pp. 465-475. https://doi.org/10.3171/2017.8.JNS17765
Brown, TJ, Bota, DA, Van Den Bent, MJ, Brown, PD, Maher, E, Aregawi, D, Liau, LM, Buckner, JC, Weller, M, Berger, MS & Glantz, M 2019, 'Management of low-grade glioma: A systematic review and meta-Analysis', Neuro-Oncology Practice, vol. 6, no. 4, npy034, pp. 249-258. https://doi.org/10.1093/nop/npy034

2017

Davis, G, Lee, M, Aregawi, D, Shaffrey, ME, Schiff, D & Sherman, JH 2017, Spinal metastasis as complication of systemic cancers. in Cancer Neurology in Clinical Practice: Neurological Complications of Cancer and its Treatment: Third Edition. Springer International Publishing, pp. 113-125. https://doi.org/10.1007/978-3-319-57901-6_6

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)