Jong Yun, PhD - Penn State Cancer Institute
Researcher Profile
Jong Yun, PhD
Associate Professor, Department of Neuroscience and Experimental Therapeutics
Center for Cannabis and Natural Product Pharmaceuticals (CCNPP)
Center for Cannabis and Natural Product Pharmaceuticals (CCNPP)
Scientific Program:Next-Generation Therapies
Recent Publications
2024
Hengst, JA, Ruiz-Velasco, VJ, Raup-Konsavage, WM, Vrana, KE & Yun, J 2024, 'Cannabinoid-Induced Immunogenic Cell Death of Colorectal Cancer Cells Through De Novo Synthesis of Ceramide Is Partially Mediated by CB2 Receptor', Cancers, vol. 16, no. 23, 3973. https://doi.org/10.3390/cancers16233973
Hengst, JA, Nduwumwami, AJ, Sharma, A & Yun, JK 2024, 'Fanning the Flames of Endoplasmic Reticulum (ER) Stress: Can Sphingolipid Metabolism Be Targeted to Enhance ER Stress–Associated Immunogenic Cell Death in Cancer?', Molecular pharmacology, vol. 105, no. 3, pp. 155-165. https://doi.org/10.1124/molpharm.123.000786
2023
Kale, VP, Hengst, JA, Sharma, AK, Golla, U, Dovat, S, Amin, SG, Yun, JK & Desai, DH 2023, 'Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases', Pharmaceuticals, vol. 16, no. 8, 1060. https://doi.org/10.3390/ph16081060
2022
Hengst, JA, Nduwumwami, AJ, Raup-Konsavage, WM, Vrana, KE & Yun, JK 2022, 'Inhibition of Sphingosine Kinase Activity Enhances Immunogenic Cell Surface Exposure of Calreticulin Induced by the Synthetic Cannabinoid 5-epi-CP-55,940', Cannabis and Cannabinoid Research, vol. 7, no. 5, pp. 637-647. https://doi.org/10.1089/can.2021.0100
Hengst, JA, Nduwumwami, AJ & Yun, JK 2022, 'Regulatory Role of Sphingosine-1-Phosphate and C16:0 Ceramide, in Immunogenic Cell Death of Colon Cancer Cells Induced by Bak/Bax-Activation', Cancers, vol. 14, no. 21, 5182. https://doi.org/10.3390/cancers14215182
2021
Nduwumwami, AJ, Hengst, JA & Yun, JK 2021, 'Sphingosine kinase inhibition enhances dimerization of calreticulin at the cell surface in mitoxantrone-induced immunogenic cell death', Journal of Pharmacology and Experimental Therapeutics, vol. 378, no. 3, pp. 300-310. https://doi.org/10.1124/jpet.121.000629