Joseph Miccio, MD - Penn State Cancer Institute
Researcher Profile
Joseph Miccio, MD
Assistant Professor and Director of Genitourinary Cancer, Department of Radiation Oncology
Scientific Program:Experimental Therapeutics
Clinical Trials
NRG-CC013: A Randomized, Masked, Placebo Controlled, Phase II Trial Of Concurrent Chemoradiation With Bmx-001 In Patients With Head And Neck Squamous Cell Carcinoma Receiving Concurrent Chemoradiation
Consolidative Use Of Radiotherapy To Block (Curb2) Oligoprogression In Patients With Metastatic Non-Small-Cell Lung Cancer - A Randomized Phase 3 Trial (BR.38)
CCTG MA.39:Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Breast Cancer
Phase III Study of PET-Directed Local or Systemic Therapy Intensification in Prostate Cancer Patients with Post-Prostatectomy Biochemical Recurrence
NRG-GU014: Randomized Phase Ii Trial of Pembrolizumab And Radiation vs. Radiation and Concurrent Chemotherapy for High-Grade T1 Bladder Cancer (PARCCTrial)
NRG-GU012: Randomized Phase II Stereotactic Ablative Radiation Therapy (SABR) For Metastatic Unresected Renal Cell Carcinoma (RCC) Receiving Immunotherapy (SAMURAI)
NRG-LU007 Randomized Phase II/III Trial Of Consolidation Radiation + Immunotherapy for ES-SCLC: RAPTOR trial
NRG-LU008: Phase III Prospective Randomized Trial Of Primary Lung Tumor Stereotactic Body Radiation Therapy Followed By Concurrent Mediastinal Chemoradiation For Locally Advanced Non-Small Cell Lung Cancer
NRG-GU013: The Phase III 'High Five Trial' Five Fraction Radiation for High-Risk Prostate Cancer
Recent Publications
2026
Miccio, JA, Potter, NJ & Machtay, M 2026, 'BID-ding wars: will dose-escalated twice daily radiotherapy for limited stage small cell lung cancer be the new standard of care? —critical analysis of the literature', Journal of Thoracic Disease, vol. 18, no. 1, 46. https://doi.org/10.21037/jtd-2025-aw-2218
Vazquez-Urrutia, JR, Venugopal, N, Zhu, J, Miccio, JA, Machtay, M & Komiya, T 2026, 'Correction: Evaluating the role of consolidative chest radiotherapy after chemo-immunotherapy in extensive-stage small cell lung cancer: a retrospective study (Discover Oncology, (2025), 16, 1, (813), 10.1007/s12672-025-02589-x)', Discover Oncology, vol. 17, no. 1, 575. https://doi.org/10.1007/s12672-026-04722-w
2025
Layng, SC, Betsock, A, Mansouri, A, Komiya, T, Miccio, JA, Mahase, SS & Knisely, JPS 2025, 'Brain metastases from lung cancer: recent advances and novel therapeutic opportunities', Discover Oncology, vol. 16, no. 1, 157. https://doi.org/10.1007/s12672-025-01873-0
azquez-Urrutia, JR, Venugopal, N, Zhu, J, Miccio, JA, Machtay, M & Komiya, T 2025, 'Evaluating the role of consolidative chest radiotherapy after chemo-immunotherapy in extensive-stage small cell lung cancer: a retrospective study', Discover Oncology, vol. 16, no. 1, 813. https://doi.org/10.1007/s12672-025-02589-x
2024
Miccio, JA, Tian, Z, Mahase, SS, Lin, C, Choi, S, Zacharia, BE, Sheehan, JP, Brown, PD, Trifiletti, DM, Palmer, JD, Wang, M & Zaorsky, NG 2024, 'Estimating the risk of brain metastasis for patients newly diagnosed with cancer', Communications Medicine, vol. 4, no. 1, 27. https://doi.org/10.1038/s43856-024-00445-7
Miccio, JA, Potter, NJ, Showkat, A, Yao, M, Mahase, S, Ferenci, M, Sisley, K, Dailey, A, Knipple, J, Blakely, A, Tuanquin, L & Machtay, M 2024, 'Single institution experience of MRI-guided radiotherapy for thoracic tumors and clinical characteristics impacting treatment duty cycle', Frontiers in Oncology, vol. 14, 1401703. https://doi.org/10.3389/fonc.2024.1401703
2023
Wolfe, S, Diven, MA, Marciscano, AE, Zhou, XK, Kishan, AU, Steinberg, ML, Miccio, JA, Camilleri, P & Nagar, H 2023, 'A randomized phase II trial of MR-guided prostate stereotactic body radiotherapy administered in 5 or 2 fractions for localized prostate cancer (FORT)', BMC Cancer, vol. 23, no. 1, 923. https://doi.org/10.1186/s12885-023-11430-z
Lorenz, FJ, Mahase, SS, Miccio, J, King, TS, Pradhan, S & Goyal, N 2023, 'Update on adherence to guidelines for time to initiation of postoperative radiation for head and neck squamous cell carcinoma', Head and Neck, vol. 45, no. 7, pp. 1676-1691. https://doi.org/10.1002/hed.27380
2022
Oladeru, OT, Ma, SJ, Miccio, JA, Wang, K, Attwood, K, Singh, AK, Haas-Kogan, DA & Neira, PM 2022, 'Breast and Cervical Cancer Screening Disparities in Transgender People', American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 45, no. 3, pp. 116-121. https://doi.org/10.1097/COC.0000000000000893
Mokhtech, M, Miccio, JA, Johung, K, Cecchini, M, Stein, S, Narang, AK, Herman, JM, Kunstman, J, Haddock, MG, Anker, CJ, Jabbour, S, Hallemeier, CL & Jethwa, KR 2022, 'Multiagent Chemotherapy Followed by Stereotactic Body Radiotherapy Versus Conventional Radiotherapy for Resected Pancreas Cancer', American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 45, no. 11, pp. 450-457. https://doi.org/10.1097/COC.0000000000000947
Gao, SJ, Jin, L, Meadows, HW, Shafman, TD, Gross, CP, Yu, JB, Aerts, HJWL, Miccio, JA, Stahl, JM, Mak, RH, Decker, RH & Kann, BH 2023, 'Prediction of Distant Metastases After Stereotactic Body Radiation Therapy for Early Stage NSCLC: Development and External Validation of a Multi-Institutional Model', Journal of Thoracic Oncology, vol. 18, no. 3, pp. 339-349. https://doi.org/10.1016/j.jtho.2022.11.007