Joseph Miccio, MD - Penn State Cancer Institute
Researcher Profile
Joseph Miccio, MD
Assistant Professor and Director of Genitourinary Cancer, Department of Radiation Oncology
Scientific Program:Next-Generation Therapies
Clinical Trials
CCTG MA.39:Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Breast Cancer
Parallel Phase III Randomized Trials of Genomic-Risk Stratified Unfavorable Intermediate Risk Prostate Cancer: De-Intensification and Intensification Clinical Trial Evaluation (GUIDANCE)
A Randomized Phase II/III Trial of Modern Immunotherapy Based Systemic Therapy With or Without Radiation Therapy for PD-L1-Negative, Advanced Non-Small Cell Lung Cancer
NRG-GU011: A Phase II Double-Blinded, Placebo-Controlled Trial of PROstate OligoMETastatic RadiotHErapy With or Without ANdrogen Deprivation Therapy in Oligometastatic Prostate Cancer (NRG Promethean)
Radiopaque Hydrogel Rectal Spacer for Prostate Cancer Radiation Image Guidance
Phase III Study of PET-Directed Local or Systemic Therapy Intensification in Prostate Cancer Patients with Post-Prostatectomy Biochemical Recurrence
NRG-BN012: A Randomized Phase III Trial of Pre-Operative Compared to Post-Operative Stereotactic Radiosurgery in Patients With Resectable Brain Metastases
Parallel Phase III Randomized Trials for High Risk Prostate Cancer Evaluating De-Intensification for Lower Genomic Risk and Intensification of Concurrent Therapy for Higher Genomic Risk with Radiation (PREDICT-RT*)
NRG-LU008: Phase III Prospective Randomized Trial Of Primary Lung Tumor Stereotactic Body Radiation Therapy Followed By Concurrent Mediastinal Chemoradiation For Locally Advanced Non-Small Cell Lung Cancer
NRG-GU013: The Phase III 'High Five Trial' Five Fraction Radiation for High-Risk Prostate Cancer
NRG-LU007 Randomized Phase II/III Trial Of Consolidation Radiation + Immunotherapy for ES-SCLC: RAPTOR trial
Recent Publications
2024
Miccio, JA, Tian, Z, Mahase, SS, Lin, C, Choi, S, Zacharia, BE, Sheehan, JP, Brown, PD, Trifiletti, DM, Palmer, JD, Wang, M & Zaorsky, NG 2024, 'Estimating the risk of brain metastasis for patients newly diagnosed with cancer', Communications Medicine, vol. 4, no. 1, 27. https://doi.org/10.1038/s43856-024-00445-7
Miccio, JA, Potter, NJ, Showkat, A, Yao, M, Mahase, S, Ferenci, M, Sisley, K, Dailey, A, Knipple, J, Blakely, A, Tuanquin, L & Machtay, M 2024, 'Single institution experience of MRI-guided radiotherapy for thoracic tumors and clinical characteristics impacting treatment duty cycle', Frontiers in Oncology, vol. 14, 1401703. https://doi.org/10.3389/fonc.2024.1401703
2023
Wolfe, S, Diven, MA, Marciscano, AE, Zhou, XK, Kishan, AU, Steinberg, ML, Miccio, JA, Camilleri, P & Nagar, H 2023, 'A randomized phase II trial of MR-guided prostate stereotactic body radiotherapy administered in 5 or 2 fractions for localized prostate cancer (FORT)', BMC Cancer, vol. 23, no. 1, 923. https://doi.org/10.1186/s12885-023-11430-z
Lorenz, FJ, Mahase, SS, Miccio, J, King, TS, Pradhan, S & Goyal, N 2023, 'Update on adherence to guidelines for time to initiation of postoperative radiation for head and neck squamous cell carcinoma', Head and Neck, vol. 45, no. 7, pp. 1676-1691. https://doi.org/10.1002/hed.27380
2022
Oladeru, OT, Ma, SJ, Miccio, JA, Wang, K, Attwood, K, Singh, AK, Haas-Kogan, DA & Neira, PM 2022, 'Breast and Cervical Cancer Screening Disparities in Transgender People', American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 45, no. 3, pp. 116-121. https://doi.org/10.1097/COC.0000000000000893
Mokhtech, M, Miccio, JA, Johung, K, Cecchini, M, Stein, S, Narang, AK, Herman, JM, Kunstman, J, Haddock, MG, Anker, CJ, Jabbour, S, Hallemeier, CL & Jethwa, KR 2022, 'Multiagent Chemotherapy Followed by Stereotactic Body Radiotherapy Versus Conventional Radiotherapy for Resected Pancreas Cancer', American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 45, no. 11, pp. 450-457. https://doi.org/10.1097/COC.0000000000000947
Gao, SJ, Jin, L, Meadows, HW, Shafman, TD, Gross, CP, Yu, JB, Aerts, HJWL, Miccio, JA, Stahl, JM, Mak, RH, Decker, RH & Kann, BH 2023, 'Prediction of Distant Metastases After Stereotactic Body Radiation Therapy for Early Stage NSCLC: Development and External Validation of a Multi-Institutional Model', Journal of Thoracic Oncology, vol. 18, no. 3, pp. 339-349. https://doi.org/10.1016/j.jtho.2022.11.007
2021
Guo, Y, Czeyda-Pommersheim, F, Miccio, JA, Mahalingam, S, Cecchini, M & Pahade, J 2021, 'Can a simplified CT response criteria for vascular involvement in pancreatic adenocarcinoma after neoadjuvant therapy predict survival in patients who achieved subsequent R0 resection?', Abdominal Radiology, vol. 46, no. 12, pp. 5609-5617. https://doi.org/10.1007/s00261-021-03284-5
Patel, T, Miccio, J, Cecchini, M, Srikumar, T, Stein, S, Kortmanksy, J, Johung, K & Lacy, J 2021, 'Clinical outcomes of first line FOLFIRINOX vs. gemcitabine plus nab-paclitaxel in metastatic pancreatic cancer at the Yale Smilow Hospital System', Journal of Gastrointestinal Oncology, vol. 13, no. 6, pp. 2547-2556. https://doi.org/10.21037/jgo-21-202
Lee, NCJ, Eskander, A, Miccio, JA, Park, HS, Shah, C, Rutenberg, M, Hosni, A & Husain, ZA 2021, 'Evaluation of head and neck soft tissue sarcoma 8th edition pathologic staging system and proposal of a novel stage grouping system', Oral Oncology, vol. 114, 105137. https://doi.org/10.1016/j.oraloncology.2020.105137
Miccio, JA, Talcott, WJ, Patel, T, Park, HS, Cecchini, M, Salem, RR, Khan, SA, Stein, S, Kortmansky, JS, Lacy, J, Narang, A, Herman, J, Jabbour, SK, Hallemeier, CL, Johung, K & Jethwa, KR 2021, 'Margin negative resection and pathologic downstaging with multiagent chemotherapy with or without radiotherapy in patients with localized pancreas cancer: A national cancer database analysis', Clinical and Translational Radiation Oncology, vol. 27, pp. 15-23. https://doi.org/10.1016/j.ctro.2020.12.003
Yang, DX, Khera, R, Miccio, JA, Jairam, V, Chang, E, Yu, JB, Park, HS, Krumholz, HM & Aneja, S 2021, 'Prevalence of Missing Data in the National Cancer Database and Association with Overall Survival', JAMA network open, vol. 4, no. 3, e211793. https://doi.org/10.1001/jamanetworkopen.2021.1793
Peters, GW, Tao, W, Wei, W, Miccio, JA, Jethwa, KR, Cecchini, M & Johung, KL 2021, 'Publication Bias in Gastrointestinal Oncology Trials Performed over the Past Decade', Oncologist, vol. 26, no. 8, pp. 660-667. https://doi.org/10.1002/onco.13759
Miccio, JA, Talcott, WJ, Jairam, V, Park, HS, Yu, JB, Leapman, MS, Johnson, SB, King, MT, Nguyen, PL & Kann, BH 2021, 'Quantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients', Prostate Cancer and Prostatic Diseases, vol. 24, no. 2, pp. 414-422. https://doi.org/10.1038/s41391-020-00291-3
Talcott, WJ, Miccio, JA, Park, HS, White, AA, Kozono, DE, Singer, L, Sands, JM, Sholl, LM, Detterbeck, FC, Mak, RH, Decker, RH & Kann, BH 2021, 'Rates of invasive disease and outcomes in NSCLC patients with biopsy suggestive of carcinoma in situ', Lung Cancer, vol. 157, pp. 17-20. https://doi.org/10.1016/j.lungcan.2021.05.028