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Researcher Profile

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Matthew D. Taylor, MD

Matthew D. Taylor, MD

Associate Professor, Department of Surgery
Division of Thoracic Surgery
Scientific Program:Next-Generation Therapies
Disease Teams:
Cancer Institute, Thoracic Cancer Team
MDT111@psu.edu

Research Interests

  • Therapeutics
  • Neoplasms
  • Survival
  • Non-Small Cell Lung Carcinoma
  • Ischemia
  • Neoplasm Metastasis
  • Lung Neoplasms
  • Recurrence
  • Esophageal Neoplasms
  • Herniorrhaphy
  • Hiatal Hernia
  • Animals

Clinical Trials

Tissue and Blood Collection from Patients with Suspected Lung Cancer
One Time Tissue and Blood Collection from Patients with Lung Cancer at Risk for Developing Lung Cancer
A randomized phase II trial of adjuvant Pembrolizumab versus observation following curative resection for stage I non-small cell lung cancer (NSCLC) with primary tumors between 1-4 cm: Big Ten Cancer Research Consortium BTCRC-LUN18-153

Recent Publications

2022

Zukowski, M, Haas, A, Schaefer, EW, Shen, C, Reed, MF, Taylor, MD & Go, PH 2022, 'Are Routine Chest Radiographs After Chest Tube Removal in Thoracic Surgery Patients Necessary?', Journal of Surgical Research, vol. 276, pp. 160-167. https://doi.org/10.1016/j.jss.2022.02.046
Holguin, RAP, Wong, WG, Shen, C, Go, PH, Reed, MF & Taylor, MD 2022, 'Esophagectomy vs Gastrectomy for Early Stage Adenocarcinoma of the Gastroesophageal Junction: What is the Optimal Oncologic Surgical Treatment?', Seminars in thoracic and cardiovascular surgery. https://doi.org/10.1053/j.semtcvs.2022.06.022
Delong, CG, Liu, AT, Taylor, MD, Lyn-Sue, JR, Winder, JS, Pauli, EM & Haluck, RS 2022, 'Esophagogastric Junction Outflow Obstruction and Hiatal Hernia: Is Hernia Repair Alone Sufficient?', Journal of the Society of Laparoendoscopic Surgeons, vol. 26, no. 4, e2022.00051. https://doi.org/10.4293/jsls.2022.00051
Perez Holguin, RA, Olecki, EJ, Wong, WG, Stahl, KA, Go, PH, Taylor, MD, Reed, MF & Shen, C 2023, 'Outcomes after sublobar resection versus lobectomy in non–small cell carcinoma in situ', Journal of Thoracic and Cardiovascular Surgery, vol. 165, no. 3, pp. 853-861.e3. https://doi.org/10.1016/j.jtcvs.2022.05.032
Wong, WG, Perez Holguin, RA, Oh, JS, Armen, SB, Taylor, MD, Reed, MF & Hollenbeak, CS 2022, 'The cost of treatments for retained traumatic hemothorax: A decision analysis', Injury, vol. 53, no. 9, pp. 2930-2938. https://doi.org/10.1016/j.injury.2022.07.021

2021

Northwell COVID-19 Research Consortium 2021, 'Comparative Survival Analysis of Immunomodulatory Therapy for Coronavirus Disease 2019 Cytokine Storm', CHEST, vol. 159, no. 3, pp. 933-948. https://doi.org/10.1016/j.chest.2020.09.275
Lin, S, Li, Y, Wang, D, Huang, C, Marino, D, Bollt, O, Wu, C, Taylor, MD, Li, W, DeNicola, GM, Hao, J, Singh, PK & Yang, S 2021, 'Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression', Cancer Letters, vol. 518, pp. 230-242. https://doi.org/10.1016/j.canlet.2021.07.025
DeLuzio, MR, Rassaei, N, Taylor, MD & Reed, MF 2021, 'Mediastinal IgG4-Related Disease Manifesting as Superior Vena Cava Syndrome', Annals of Thoracic Surgery, vol. 112, no. 1, pp. e49-e51. https://doi.org/10.1016/j.athoracsur.2020.10.064

2020

Lin, S, Taylor, MD, Singh, PK & Yang, S 2021, 'How does fascin promote cancer metastasis?', FEBS Journal, vol. 288, no. 5, pp. 1434-1446. https://doi.org/10.1111/febs.15484
National Audit of Small Bowel Obstruction Steering Group and National Audit of Small Bowel Obstruction Collaborators, NASBO Steering Group, NASBO Collaborators & West Midlands Research Collaborative 2020, 'Outcomes of obstructed abdominal wall hernia: results from the UK national small bowel obstruction audit', BJS open, vol. 4, no. 5, pp. 924-934. https://doi.org/10.1002/bjs5.50315
Hendriksen, BS, Stahl, KA, Hollenbeak, CS, Taylor, MD, Vasekar, MK, Drabick, JJ, Conte, JV, Soleimani, B & Reed, MF 2021, 'Postoperative chemotherapy and radiation improve survival following cardiac sarcoma resection', Journal of Thoracic and Cardiovascular Surgery, vol. 161, no. 1, pp. 110-119.e4. https://doi.org/10.1016/j.jtcvs.2019.10.016

2019

Hendriksen, BS, Kuroki, MT, Armen, SB, Reed, MF, Taylor, MD & Hollenbeak, CS 2019, 'Lytic Therapy for Retained Traumatic Hemothorax: A Systematic Review and Meta-analysis', CHEST, vol. 155, no. 4, pp. 805-815. https://doi.org/10.1016/j.chest.2019.01.007
Hendriksen, BS, Hollenbeak, CS, Taylor, MD & Reed, MF 2019, 'Minimally Invasive Lobectomy Modality and Other Predictors of Conversion to Thoracotomy', Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, vol. 14, no. 4, pp. 342-352. https://doi.org/10.1177/1556984519849037
on behalf of NASBO steering group and NASBO collaborators 2019, 'National prospective cohort study of the burden of acute small bowel obstruction', BJS open, vol. 3, no. 3, pp. 354-366. https://doi.org/10.1002/bjs5.50136
National Audit of Small Bowel Obstruction Steering Group & National Audit of Small Bowel Obstruction Collaborators 2019, 'Outcomes following small bowel obstruction due to malignancy in the national audit of small bowel obstruction', European Journal of Surgical Oncology, vol. 45, no. 12, pp. 2319-2324. https://doi.org/10.1016/j.ejso.2019.07.014
Hendriksen, BS, Hollenbeak, CS, Reed, MF & Taylor, MD 2019, 'Perioperative chemotherapy is not associated with improved survival in stage I pleomorphic lung cancer', Journal of Thoracic and Cardiovascular Surgery, vol. 158, no. 2, pp. 581-591.e11. https://doi.org/10.1016/j.jtcvs.2019.04.005
Hendriksen, BS, Reed, MF, Taylor, MD & Hollenbeak, CS 2019, 'Readmissions After Lobectomy in an Era of Increasing Minimally Invasive Surgery: A Statewide Analysis', Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, vol. 14, no. 5, pp. 453-462. https://doi.org/10.1177/1556984519874064
Walsh, LT, Loloi, J, Manzo, CE, Mathew, A, Maranki, J, Dye, CE, Levenick, JM, Taylor, MD & Moyer, MT 2019, 'Successful treatment of large cavity esophageal disruptions with transluminal washout and endoscopic vacuum therapy: a report of two cases', Therapeutic Advances in Gastrointestinal Endoscopy, vol. 12. https://doi.org/10.1177/2631774519860300
Hendriksen, BS, Brooks, AJ, Hollenbeak, CS, Taylor, MD, Reed, MF & Soybel, DI 2020, 'The Impact of Minimally Invasive Gastrectomy on Survival in the USA', Journal of Gastrointestinal Surgery, vol. 24, no. 5, pp. 1000-1009. https://doi.org/10.1007/s11605-019-04263-4
Lin, S, Huang, C, Sun, J, Bollt, O, Wang, X, Martine, E, Kang, J, Taylor, MD, Fang, B, Singh, PK, Koomen, J, Hao, J & Yang, S 2019, 'The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma', EMBO Molecular Medicine, vol. 11, no. 12, e10849. https://doi.org/10.15252/emmm.201910849