Head and Neck Cancer Research - Penn State Cancer Institute
Head and Neck Cancer Research
Research into head and neck cancer at Penn State Cancer Institute is conducted by the dedicated head and neck cancer team. See current clinical trials and members of that team here.
Clinical Trials
Radiographic Detection of Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)
Head and Neck Cells: Salivary Tissue Repository
The COVID-19 and Cancer Consortium (CCC19) Registry
Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer
Psychosocial Challenges and Educational/Occupational Aspirations of Adolescent/Young Adult Cancer Survivors
Dysgeusia and Anosmia in Head and Neck Cancer Patients: Long Term Outcomes
A Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of AAV2-hAQP1 Gene Therapy in Participants with Radiation-Induced Late Xerostomia (RIX)
A Dose-Escalation and Expansion Study of the Safety and Efficacy of XL092 in Combination With Immuno-Oncology Agents in Subjects With Unresectable Advanced or Metastatic Solid Tumors
Vaccine Talks: Evaluating the feasibility of a podcast intervention to improve provider communication about HPV vaccination
TRANSPARENT: Single-Arm Study of Toripalimab in Combination with Cisplatin and Gemcitabine in Recurrent Metastatic Nasopharyngeal Carcinoma Systemic Treatment Naïve Participants
Exploring Factors Associated with Understanding Among Head and Neck Surgery Patients
NRG-CC013: A Randomized, Masked, Placebo Controlled, Phase II Trial Of Concurrent Chemoradiation With Bmx-001 In Patients With Head And Neck Squamous Cell Carcinoma Receiving Concurrent Chemoradiation
Long-term Follow-up of AAV2-hAQP1 Gene Therapy in Participants with Radiation-Induced Late Xerostomia- MGT-AQP1-202
SN2426: A Randomized Phase II Study of Amivantamab (JNJ-61186372) and
hyaluronidase (rHuPH20) versus Cetuximab in Immunocompromised Participants with
Recurrent Inoperable or Metastatic Cutaneous Squamous Cell Carcinoma
Head and Neck Cells: Tissue Repository
Disease Team Members
| First Name | Last Name | Title | Role | ||
|---|---|---|---|---|---|
![]() |
Melissa | Boltz | DO | ||
![]() |
David | Goldenberg | MD | ||
![]() |
Neerav | Goyal | MD, MPH | ||
![]() |
Jessyka | Lighthall | MD | ||
![]() |
Mitchell | Machtay | MD | ||
![]() |
Brian | Saunders | MD |
Research into head and neck cancer at Penn State Cancer Institute is conducted by the dedicated head and neck cancer team. See current clinical trials and members of that team here.
Radiographic Detection of Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)
Head and Neck Cells: Salivary Tissue Repository
The COVID-19 and Cancer Consortium (CCC19) Registry
Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer
Psychosocial Challenges and Educational/Occupational Aspirations of Adolescent/Young Adult Cancer Survivors
Dysgeusia and Anosmia in Head and Neck Cancer Patients: Long Term Outcomes
A Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of AAV2-hAQP1 Gene Therapy in Participants with Radiation-Induced Late Xerostomia (RIX)
A Dose-Escalation and Expansion Study of the Safety and Efficacy of XL092 in Combination With Immuno-Oncology Agents in Subjects With Unresectable Advanced or Metastatic Solid Tumors
Vaccine Talks: Evaluating the feasibility of a podcast intervention to improve provider communication about HPV vaccination
TRANSPARENT: Single-Arm Study of Toripalimab in Combination with Cisplatin and Gemcitabine in Recurrent Metastatic Nasopharyngeal Carcinoma Systemic Treatment Naïve Participants
Exploring Factors Associated with Understanding Among Head and Neck Surgery Patients
NRG-CC013: A Randomized, Masked, Placebo Controlled, Phase II Trial Of Concurrent Chemoradiation With Bmx-001 In Patients With Head And Neck Squamous Cell Carcinoma Receiving Concurrent Chemoradiation
Long-term Follow-up of AAV2-hAQP1 Gene Therapy in Participants with Radiation-Induced Late Xerostomia- MGT-AQP1-202
SN2426: A Randomized Phase II Study of Amivantamab (JNJ-61186372) and
hyaluronidase (rHuPH20) versus Cetuximab in Immunocompromised Participants with
Recurrent Inoperable or Metastatic Cutaneous Squamous Cell Carcinoma
Head and Neck Cells: Tissue Repository
| First Name | Last Name | Title | Role | ||
|---|---|---|---|---|---|
![]() |
Melissa | Boltz | DO | ||
![]() |
David | Goldenberg | MD | ||
![]() |
Neerav | Goyal | MD, MPH | ||
![]() |
Jessyka | Lighthall | MD | ||
![]() |
Mitchell | Machtay | MD | ||
![]() |
Brian | Saunders | MD |






