Breast Cancer Research - Penn State Cancer Institute
Breast Cancer Research
Research into breast cancer at Penn State Cancer Institute is conducted by a dedicated breast cancer team. See current clinical trials and members of that team here.
Clinical Trials
CUFF Study: Characterization of Upper Limb Function following Mastectomy and Reconstruction for Breast Cancer
Using Exercise to Improve Arthralgia and AI Adherence in Older Breast Cancer Survivors
The COVID-19 and Cancer Consortium (CCC19) Registry
Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III
A Phase II, Single Arm, Non-randomized Study of Alpelisib (BYL719) in Combination with Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer Big Ten Cancer Research Consortium BTCRC-BRE19-409
Prospective evaluation of potential effects of repeated gadoliniumbased contrast agent (GBCA) administrations of the same GBCA on motor and cognitive functions in neurologically normal adults in comparison to a non-GBCA exposed control group ODYSSEY
Trial Assessing Light-Intensity Exercise on the Health of Older Breast Cancer Survivors (TALIE-HO Breast Cancer Survivors)
NRG-BR007: A Phase III Clinical Trial Evaluating Deescalation of Breast Radiation for Conservative Treatment of Stage I, Hormone sensitive, HER2- Negative Oncotype recurrence Score ≤ 18 Breast Cancer
A Phase II Study of Ribociclib and Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer (RaPhLRR Study) (HCRN-BRE20-468)
A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/or Axillary Lymph Nodes at Surgical Resection Following Neoadjuvant Systemic Therapy(TROPION-Breast03)
A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 (an Oral SERD) plus Palbociclib versus Anastrozole plus Palbociclib for the Treatment of Patients with Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease
CCTG MA.39:Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Breast Cancer
Attitudes towards cannabis use in the PSCI cancer population
An Open Label, Phase II Trial of Pre-operative Neratinib and Endocrine Therapy with Trastuzumab in Triple Positive Breast Cancers
Adapting an Advance Care Planning Intervention and Delivery model for Use with Patients with Advanced Cancer and their Caregivers
Disease Team Members
| First Name | Last Name | Title | Role | ||
|---|---|---|---|---|---|
 |
Alison | Chetlen | DO | ||
 |
Daleela | Dodge | MD | ||
 |
Claudia | Kasales | MD | ||
 |
Rena | Kass | MD | ||
 |
Julie | Mack | MD | ||
 |
John | Potochny | MD | ||
 |
Rebecca | Sivarajah | MD | ||
 |
Cristina | Truica | MD | ||
 |
Kristine | Widders | MD |
Research into breast cancer at Penn State Cancer Institute is conducted by a dedicated breast cancer team. See current clinical trials and members of that team here.
CUFF Study: Characterization of Upper Limb Function following Mastectomy and Reconstruction for Breast Cancer
Using Exercise to Improve Arthralgia and AI Adherence in Older Breast Cancer Survivors
The COVID-19 and Cancer Consortium (CCC19) Registry
Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III
A Phase II, Single Arm, Non-randomized Study of Alpelisib (BYL719) in Combination with Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer Big Ten Cancer Research Consortium BTCRC-BRE19-409
Prospective evaluation of potential effects of repeated gadoliniumbased contrast agent (GBCA) administrations of the same GBCA on motor and cognitive functions in neurologically normal adults in comparison to a non-GBCA exposed control group ODYSSEY
Trial Assessing Light-Intensity Exercise on the Health of Older Breast Cancer Survivors (TALIE-HO Breast Cancer Survivors)
NRG-BR007: A Phase III Clinical Trial Evaluating Deescalation of Breast Radiation for Conservative Treatment of Stage I, Hormone sensitive, HER2- Negative Oncotype recurrence Score ≤ 18 Breast Cancer
A Phase II Study of Ribociclib and Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer (RaPhLRR Study) (HCRN-BRE20-468)
A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/or Axillary Lymph Nodes at Surgical Resection Following Neoadjuvant Systemic Therapy(TROPION-Breast03)
A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 (an Oral SERD) plus Palbociclib versus Anastrozole plus Palbociclib for the Treatment of Patients with Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease
CCTG MA.39:Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive and T3N0 Breast Cancer
Attitudes towards cannabis use in the PSCI cancer population
An Open Label, Phase II Trial of Pre-operative Neratinib and Endocrine Therapy with Trastuzumab in Triple Positive Breast Cancers
Adapting an Advance Care Planning Intervention and Delivery model for Use with Patients with Advanced Cancer and their Caregivers
| First Name | Last Name | Title | Role | ||
|---|---|---|---|---|---|
|
Alison | Chetlen | DO | ||
|
Daleela | Dodge | MD | ||
|
Claudia | Kasales | MD | ||
|
Rena | Kass | MD | ||
|
Julie | Mack | MD | ||
|
John | Potochny | MD | ||
|
Rebecca | Sivarajah | MD | ||
|
Cristina | Truica | MD | ||
|
Kristine | Widders | MD |