Breast Cancer Research

Breast Cancer Research

Research into breast cancer at Penn State Cancer Institute is conducted by a dedicated breast cancer team. See current clinical trials and members of that team here.

Clinical Trials

CUFF Study: Characterization of Upper Limb Function following Mastectomy and Reconstruction for Breast Cancer
Using Exercise to Improve Arthralgia and AI Adherence in Older Breast Cancer Survivors
Diminish Chemotherapy Related Side Effects through Patient Education
The COVID-19 and Cancer Consortium (CCC19) Registry
EA1181 (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response Part 1 Component of:The CompassHER2 Trials (COMprehensive use of Pathologic response Assessment to optimize therapy in HER2-positive breast cancer).
A Phase III, Randomized, Open-label, Multicenter Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared with Physician's Choice of Adjuvant Endocrine Monotherapy in Patients with Estrogen Receptor-Positive, Her2-negative Early Breast Cancer (B-61) Lidera
Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III
A Phase II, Single Arm, Non-randomized Study of Alpelisib (BYL719) in Combination with Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer Big Ten Cancer Research Consortium BTCRC-BRE19-409
Prospective evaluation of potential effects of repeated gadoliniumbased contrast agent (GBCA) administrations of the same GBCA on motor and cognitive functions in neurologically normal adults in comparison to a non-GBCA exposed control group ODYSSEY
Trial Assessing Light-Intensity Exercise on the Health of Older Breast Cancer Survivors (TALIE-HO Breast Cancer Survivors)
NRG-BR007: A Phase III Clinical Trial Evaluating Deescalation of Breast Radiation for Conservative Treatment of Stage I, Hormone sensitive, HER2- Negative Oncotype recurrence Score ≤ 18 Breast Cancer
Women In Steady Exercise Research - Window of Opportunity for Exercise and Tumor Biology (WISER-Win)
Research into breast cancer at Penn State Cancer Institute is conducted by a dedicated breast cancer team. See current clinical trials and members of that team here.
CUFF Study: Characterization of Upper Limb Function following Mastectomy and Reconstruction for Breast Cancer
Using Exercise to Improve Arthralgia and AI Adherence in Older Breast Cancer Survivors
Diminish Chemotherapy Related Side Effects through Patient Education
The COVID-19 and Cancer Consortium (CCC19) Registry
EA1181 (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response Part 1 Component of:The CompassHER2 Trials (COMprehensive use of Pathologic response Assessment to optimize therapy in HER2-positive breast cancer).
A Phase III, Randomized, Open-label, Multicenter Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared with Physician's Choice of Adjuvant Endocrine Monotherapy in Patients with Estrogen Receptor-Positive, Her2-negative Early Breast Cancer (B-61) Lidera
Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III
A Phase II, Single Arm, Non-randomized Study of Alpelisib (BYL719) in Combination with Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer Big Ten Cancer Research Consortium BTCRC-BRE19-409
Prospective evaluation of potential effects of repeated gadoliniumbased contrast agent (GBCA) administrations of the same GBCA on motor and cognitive functions in neurologically normal adults in comparison to a non-GBCA exposed control group ODYSSEY
Trial Assessing Light-Intensity Exercise on the Health of Older Breast Cancer Survivors (TALIE-HO Breast Cancer Survivors)
NRG-BR007: A Phase III Clinical Trial Evaluating Deescalation of Breast Radiation for Conservative Treatment of Stage I, Hormone sensitive, HER2- Negative Oncotype recurrence Score ≤ 18 Breast Cancer
Women In Steady Exercise Research - Window of Opportunity for Exercise and Tumor Biology (WISER-Win)

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)