Gastrointestinal Cancer Research

Gastrointestinal Cancer Research

Research into gastrointestinal cancer at Penn State Cancer Institute is conducted by our dedicated gastrointestinal cancer team. See current clinical trials and members of that team here.

Clinical Trials

Communication Preferences Related to Over Screening for Cancer Among Older Adults
CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts: a prospective, randomized, double-blind, multi-center clinical trial
A Phase II Study to Evaluate the Response and Tolerability of Verzenio(Abemaciclib) in Patients with Advanced Biliary Tract Carcinoma who have Failed Prior Chemotherapy
A Phase II Study to Evaluate the Efficacy of Nanoliposomal Irinotecan in Combination with Oxaliplatin, Leucovorin, and 5-Fuorouracil for Patients with Locally Advanced Pancreatic Carcinoma: Big Ten Cancer Research Consortium BTCRC-GI15-067
Micro/nano technology for extracellular vesicle isolation and towards non-invasive pancreatic cancer diagnosis
Self-sampling for cancer tests among women in PA: Focus groups
A Phase III Multicenter, Randomized, Double-blinded, Active-controlled, Clinical Study to Evaluate the Safety and Efficacy of Lenvatinib (E7080/MK-7902) with Pembrolizumab (MK-3475) in Combination with Transarterial Chemoembolization (TACE) Versus TACE in Participants with Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012)(LEAP-012)
A Phase I/II Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C mutation (MRT849-001)
Diminish Chemotherapy Related Side Effects through Patient Education
The COVID-19 and Cancer Consortium (CCC19) Registry
Increasing cancer screening among women in rural and segregated areas: A multilevel intervention based on self-screening and adapted educational materials
CRESTONE: A Phase 2 Study of Seribantumab in Adult Patients with Neuregulin-1 (NRG1) Fusion Positive Locally Advanced or Metastatic Solid Tumors
A Randomized, Phase 2 Study of Stereotactic Body Radiation Therapy (SBRT) in combination with GC4711 in the Treatment of Unresectable or Borderline Resectable, Nonmetastatic Pancreatic Cancer
COVID-19 Vaccination in Cancer Patients COVID-19 Vaccination Behavior and Outcomes in Cancer Patients
EA2197: Optimal Perioperative Therapy For Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial
A mixed-methods implementation evaluation of a pilot study to increase self-sampling for cancer screening: Interviews with previous study participants
Pathologic Study of Neuroendocrine Tumors in the Digestive System
Pathological Study of Pancreaticobiliary Tumors
Complications from Major Abdominal Cancer Surgery & Their Effect on Cancer-Specific Outcomes
Frailty Assessment vs. Short Physical Performance Battery in Post-Operative Major Abdominal Surgery
New Tumor Markers for Pancreatic Cancer in Blood
Research into gastrointestinal cancer at Penn State Cancer Institute is conducted by our dedicated gastrointestinal cancer team. See current clinical trials and members of that team here.
Communication Preferences Related to Over Screening for Cancer Among Older Adults
CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts: a prospective, randomized, double-blind, multi-center clinical trial
A Phase II Study to Evaluate the Response and Tolerability of Verzenio(Abemaciclib) in Patients with Advanced Biliary Tract Carcinoma who have Failed Prior Chemotherapy
A Phase II Study to Evaluate the Efficacy of Nanoliposomal Irinotecan in Combination with Oxaliplatin, Leucovorin, and 5-Fuorouracil for Patients with Locally Advanced Pancreatic Carcinoma: Big Ten Cancer Research Consortium BTCRC-GI15-067
Micro/nano technology for extracellular vesicle isolation and towards non-invasive pancreatic cancer diagnosis
Self-sampling for cancer tests among women in PA: Focus groups
A Phase III Multicenter, Randomized, Double-blinded, Active-controlled, Clinical Study to Evaluate the Safety and Efficacy of Lenvatinib (E7080/MK-7902) with Pembrolizumab (MK-3475) in Combination with Transarterial Chemoembolization (TACE) Versus TACE in Participants with Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012)(LEAP-012)
A Phase I/II Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C mutation (MRT849-001)
Diminish Chemotherapy Related Side Effects through Patient Education
The COVID-19 and Cancer Consortium (CCC19) Registry
Increasing cancer screening among women in rural and segregated areas: A multilevel intervention based on self-screening and adapted educational materials
CRESTONE: A Phase 2 Study of Seribantumab in Adult Patients with Neuregulin-1 (NRG1) Fusion Positive Locally Advanced or Metastatic Solid Tumors
A Randomized, Phase 2 Study of Stereotactic Body Radiation Therapy (SBRT) in combination with GC4711 in the Treatment of Unresectable or Borderline Resectable, Nonmetastatic Pancreatic Cancer
COVID-19 Vaccination in Cancer Patients COVID-19 Vaccination Behavior and Outcomes in Cancer Patients
EA2197: Optimal Perioperative Therapy For Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial
A mixed-methods implementation evaluation of a pilot study to increase self-sampling for cancer screening: Interviews with previous study participants
Pathologic Study of Neuroendocrine Tumors in the Digestive System
Pathological Study of Pancreaticobiliary Tumors
Complications from Major Abdominal Cancer Surgery & Their Effect on Cancer-Specific Outcomes
Frailty Assessment vs. Short Physical Performance Battery in Post-Operative Major Abdominal Surgery
New Tumor Markers for Pancreatic Cancer in Blood

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)