Researcher Profile

Researcher Profile

Hiroko Shike, MD, MS

Hiroko Shike, MD, MS

Assistant Professor, Department of Pathology and Laboratory Medicine
Division of Clinical Pathology
Scientific Program:Next-Generation Therapies

Research Interests

  • Mucocutaneous Lymph Node Syndrome
  • Child
  • Genes
  • Gene Expression
  • Peptides
  • Tissue Donors
  • Infection
  • Polymerase Chain Reaction
  • Acute Disease
  • Bass
  • Coronary Vessels
  • Insecta

Recent Publications


Jia, B, Zhao, C, Rakszawski, KL, Claxton, DF, Christopher Ehmann, W, Rybka, WB, Mineishi, S, Wang, M, Shike, H, Bayerl, MG, Sivik, JM, Schell, TD, Drabick, JJ, Hohl, RJ & Zheng, H 2019, 'Eomes+T-betlow CD8+ T cells are functionally impaired and are associated with poor clinical outcome in patients with acute myeloid leukemia', Cancer Research, vol. 79, no. 7, pp. 1635-1645.
Shimizu, C, Kim, J, Eleftherohorinou, H, Wright, VJ, Hoang, LT, Tremoulet, AH, Franco, A, Hibberd, ML, Takahashi, A, Kubo, M, Ito, K, Tanaka, T, Onouchi, Y, Coin, LJM, Levin, M, Burns, JC & Shike, H 2019, 'HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease', Human Immunology, vol. 80, no. 9, pp. 731-738.
Tyler, J, Kumer, L, Fisher, C, Casey, H & Shike, H 2019, 'Personalized Chimerism Test that Uses Selection of Short Tandem Repeat or Quantitative PCR Depending on Patient's Chimerism Status', Journal of Molecular Diagnostics, vol. 21, no. 3, pp. 483-490.


Jia, B, Wang, L, Claxton, DF, Ehmann, WC, Rybka, WB, Mineishi, S, Rizvi, S, Shike, H, Bayerl, M, Schell, TD, Hohl, RJ & Zheng, H 2018, 'Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients', Blood Cancer Journal, vol. 8, no. 3, 34.
Rakszawski, KL, Miki, K, Claxton, D, Wagner, H, Shike, H, Mineishi, S & Naik, S 2018, 'Clofarabine followed by haploidentical stem cell transplant using fludarabine, busulfan, and total-body irradiation with post-transplant cyclophosphamide in non-remission AML', International journal of hematology, vol. 108, no. 3, pp. 348-350.
Shike, H, Kadry, Z, Imamura-Kawasawa, Y, Greene, W, Riley, T, Nathan, HM, Hasz, RD & Jain, A 2018, 'Hepatitis C virus (HCV) RNA level in plasma and kidney tissue in HCV antibody-positive donors: Quantitative comparison', Clinical Transplantation, vol. 32, no. 9, e13358.
Lokhandwala, PM, Shike, H, Wang, M, Domen, RE & George, MR 2018, 'Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections', PloS one, vol. 13, no. 5, e0198062.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)