Researcher Profile

Researcher Profile

Hiroko Shike, MD, MS

Hiroko Shike, MD, MS

Assistant Professor, Department of Pathology and Laboratory Medicine
Division of Clinical Pathology
Scientific Program:Experimental Therapeutics
hus14@psu.edu

Research Interests

  • Mucocutaneous Lymph Node Syndrome
  • Genes
  • Gene Expression
  • Peptides
  • Acute Disease
  • Tissue Donors
  • Infection
  • Polymerase Chain Reaction
  • Bass
  • Coronary Vessels
  • Insects
  • Transplants

Recent Publications

2019

Jia, B, Zhao, C, Rakszawski, KL, Claxton, D, Ehmann, WC, Rybka, W, Mineishi, S, Wang, M, Shike, H, Bayerl, M, Sivik, JM, Schell, T, Drabick, J, Hohl, R & Zheng, H 2019, 'Eomes+T-betlow CD8+ T cells are functionally impaired and are associated with poor clinical outcome in patients with acute myeloid leukemia', Cancer Research, vol. 79, no. 7, pp. 1635-1645. https://doi.org/10.1158/0008-5472.CAN-18-3107
Shimizu, C, Kim, J, Eleftherohorinou, H, Wright, VJ, Hoang, LT, Tremoulet, AH, Franco, A, Hibberd, ML, Takahashi, A, Kubo, M, Ito, K, Tanaka, T, Onouchi, Y, Coin, LJM, Levin, M, Burns, JC & Shike, H 2019, 'HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease', Human Immunology. https://doi.org/10.1016/j.humimm.2019.04.020
Tyler, J, Kumer, L, Fisher, C, Casey, H & Shike, H 2019, 'Personalized Chimerism Test that Uses Selection of Short Tandem Repeat or Quantitative PCR Depending on Patient's Chimerism Status' Journal of Molecular Diagnostics, vol. 21, no. 3, pp. 483-490. https://doi.org/10.1016/j.jmoldx.2019.01.007

2018

Jia, B, Wang, L, Claxton, D, Ehmann, WC, Rybka, W, Mineishi, S, Rizvi, S, Shike, H, Bayerl, M, Schell, T, Hohl, R & Zheng, H 2018, 'Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients', Blood Cancer Journal, vol. 8, no. 3, 34. https://doi.org/10.1038/s41408-018-0069-4
Rakszawski, K, Miki, K, Claxton, D, Wagner, H, Shike, H, Mineishi, S & Naik, S 2018, 'Clofarabine followed by haploidentical stem cell transplant using fludarabine, busulfan, and total-body irradiation with post-transplant cyclophosphamide in non-remission AML', International journal of hematology, vol. 108, no. 3, pp. 348-350. https://doi.org/10.1007/s12185-018-2431-5
Shike, H, Kadry, Z, Imamura, Y, Greene, W, Riley III, T, Nathan, HM, Hasz, RD & Jain, A 2018, 'Hepatitis C virus (HCV) RNA level in plasma and kidney tissue in HCV antibody-positive donors: Quantitative comparison' Clinical Transplantation, vol. 32, no. 9, e13358. https://doi.org/10.1111/ctr.13358
Lokhandwala, PM, Shike, H, Wang, M, Domen, R & George, M 2018, 'Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections' PloS one, vol. 13, no. 5, e0198062. https://doi.org/10.1371/journal.pone.0198062

2015

Habig, DF, Gaspari, JL, Lokhandwala, PM, Domen, R, Abendroth, C, Kadry, Z, Ghahramani, N, Shah, RA, Jain, A & Shike, H 2015, 'Donor-specific antibody to trans-encoded donor HLA-DQ heterodimer' Human Immunology, vol. 76, no. 8, pp. 587-590. https://doi.org/10.1016/j.humimm.2015.09.004

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