Researcher Profile

Researcher Profile

Hiroko Shike, MD, MS

Hiroko Shike, MD, MS

Associate Professor, Department of Pathology and Laboratory Medicine
Division of Clinical Pathology
Scientific Program:Next-Generation Therapies

Research Interests

  • Mucocutaneous Lymph Node Syndrome
  • Child
  • Genes
  • Gene Expression
  • Peptides
  • Tissue Donors
  • Infection
  • Polymerase Chain Reaction
  • Acute Disease
  • Bass
  • Alleles
  • Coronary Vessels

Recent Publications


Fisher, C, Casey, H, Kumer, L, Tyler, J & Shike, H 2020, 'A novel null allele, HLA-DPA1*01:35N in a European American Male from Pennsylvania, USA', HLA, vol. 96, no. 3, pp. 378-379.


Jia, B, Zhao, C, Rakszawski, KL, Claxton, DF, Christopher Ehmann, W, Rybka, WB, Mineishi, S, Wang, M, Shike, H, Bayerl, MG, Sivik, JM, Schell, TD, Drabick, JJ, Hohl, RJ & Zheng, H 2019, 'Eomes+T-betlow CD8+ T cells are functionally impaired and are associated with poor clinical outcome in patients with acute myeloid leukemia', Cancer Research, vol. 79, no. 7, pp. 1635-1645.
Shimizu, C, Kim, J, Eleftherohorinou, H, Wright, VJ, Hoang, LT, Tremoulet, AH, Franco, A, Hibberd, ML, Takahashi, A, Kubo, M, Ito, K, Tanaka, T, Onouchi, Y, Coin, LJM, Levin, M, Burns, JC & Shike, H 2019, 'HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease', Human Immunology, vol. 80, no. 9, pp. 731-738.
Tyler, J, Kumer, L, Fisher, C, Casey, H & Shike, H 2019, 'Personalized Chimerism Test that Uses Selection of Short Tandem Repeat or Quantitative PCR Depending on Patient's Chimerism Status', Journal of Molecular Diagnostics, vol. 21, no. 3, pp. 483-490.


Jia, B, Wang, L, Claxton, DF, Ehmann, WC, Rybka, WB, Mineishi, S, Rizvi, S, Shike, H, Bayerl, M, Schell, TD, Hohl, RJ & Zheng, H 2018, 'Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients', Blood Cancer Journal, vol. 8, no. 3, 34.
Rakszawski, K, Miki, K, Claxton, D, Wagner Jr., H, Shike, H, Mineishi, S & Naik, S 2018, 'Clofarabine followed by haploidentical stem cell transplant using fludarabine, busulfan, and total-body irradiation with post-transplant cyclophosphamide in non-remission AML', International journal of hematology, vol. 108, no. 3, pp. 348-350.
Shike, H, Kadry, Z, Imamura-Kawasawa, Y, Greene, W, Riley, T, Nathan, HM, Hasz, RD & Jain, A 2018, 'Hepatitis C virus (HCV) RNA level in plasma and kidney tissue in HCV antibody-positive donors: Quantitative comparison', Clinical Transplantation, vol. 32, no. 9, e13358.
Lokhandwala, PM, Shike, H, Wang, M, Domen, RE & George, MR 2018, 'Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections', PloS one, vol. 13, no. 5, e0198062.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)