Nelson Shu-Sang Yee, MD, PhD, RPh - Penn State Cancer Institute
Researcher Profile
Nelson Shu-Sang Yee, MD, PhD, RPh
Professor, Department of Medicine
Division of Hematology and Oncology
Division of Hematology and Oncology
Scientific Program:Next-Generation Therapies
Disease Teams:
Cancer Institute, Gastrointestinal Cancer Team
Cancer Institute, Liver, Pancreas and Foregut Cancer Team
Cancer Institute, Liver, Pancreas and Foregut Cancer Team
Clinical Trials
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US) (NRG-GI008)
Micro/nano technology for extracellular vesicle isolation and towards non-invasive pancreatic cancer diagnosis
The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing The Efficacy of Triplet Versus Doublet Chemotherapy to Achieve Clinical Complete Response in Patients With Locally Advanced Rectal Cancer
Cancer biobank for developing novel diagnostic biomarkers and therapeutic targets
A Phase III Trial Of Perioperative Versus Adjuvant Chemotherapy For Resectable Pancreatic Cancer
A Phase 1b/2, Dose-escalation, Randomized, Multicenter Study of Maintenance Ivaltinostat plus Capecitabine or Capecitabine Monotherapy in Patients with Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on First Line FOLFIRINOX Chemotherapy
Recent Publications
2025
Mareboina, M, Bakhl, K, Agioti, S, Yee, NS, Georgakopoulos-Soares, I & Zaravinos, A 2025, 'Comprehensive Analysis of Granzymes and Perforin Family Genes in Multiple Cancers', Biomedicines, vol. 13, no. 2, 408. https://doi.org/10.3390/biomedicines13020408
2024
Mareboina, M, Deng, E, Mouratidis, I, Yee, NS, Pitteloud, N, Georgakopoulos-Soares, I & Chartoumpekis, DV 2024, 'A review on cell-free RNA profiling: Insights into metabolic diseases and predictive value for bariatric surgery outcomes', Molecular Metabolism, vol. 87, 101987. https://doi.org/10.1016/j.molmet.2024.101987
McGillen, KL, Pryor, WW, Yee, NS, Zhu, J, Krok, KL & Waybill, PN 2024, 'Accuracy of Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma Post-Transcatheter Arterial Embolization', Journal of Clinical Medicine, vol. 13, no. 24, 7720. https://doi.org/10.3390/jcm13247720
Burke, CE, Eng, NL, Yee, NS & Peng, JS 2024, 'Complete response to chemotherapy in a 6-year survivor of metastatic pancreatic cancer', BMJ case reports, vol. 17, no. 7, e261008. https://doi.org/10.1136/bcr-2024-261008
Tsiatsianis, GC, Chan, CSY, Mouratidis, I, Chantzi, N, Tsiatsiani, AM, Yee, NS, Zaravinos, A, Kantere, V & Georgakopoulos-Soares, I 2024, 'Peptide absent sequences emerging in human cancers', European Journal of Cancer, vol. 196, 113421. https://doi.org/10.1016/j.ejca.2023.113421
Montgomery, A, Tsiatsianis, GC, Mouratidis, I, Chan, CSY, Athanasiou, M, Papanastasiou, AD, Kantere, V, Syrigos, N, Vathiotis, I, Syrigos, K, Yee, NS & Georgakopoulos-Soares, I 2024, 'Utilizing nullomers in cell-free RNA for early cancer detection', Cancer gene therapy, vol. 31, no. 6, pp. 861-870. https://doi.org/10.1038/s41417-024-00741-3
2023
Waldstein, S, Spengler, M, Pinchuk, IV & Yee, NS 2023, 'Impact of Colorectal Cancer Sidedness and Location on Therapy and Clinical Outcomes: Role of Blood-Based Biopsy for Personalized Treatment', Journal of Personalized Medicine, vol. 13, no. 7, 1114. https://doi.org/10.3390/jpm13071114
Linscott, MP, Markus, H, Sennett, M, Abendroth, C & Yee, NS 2023, 'Nab-Paclitaxel and Gemcitabine as First-Line Treatment of Metastatic Ampullary Adenocarcinoma with a Novel R-Spondin2 RNA Fusion and NTRK3 Mutation', Biomedicines, vol. 11, no. 8, 2326. https://doi.org/10.3390/biomedicines11082326
2022
Kumar, R, Tchelebi, L, Anker, CJ, Sharma, N, Bianchi, NA, Dragovic, J, Goodman, KA, Herman, JM, Jiang, Y, Jones, WE, Kennedy, TJ, Lee, P, Kundranda, M, Russo, S, Small, W, Suh, WW, Yee, N & Jabbour, SK 2022, 'American Radium Society (ARS) Appropriate Use Criteria (AUC) for Locoregional Gastric Adenocarcinoma: Systematic Review and Guidelines', American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 45, no. 9, pp. 391-402. https://doi.org/10.1097/COC.0000000000000930
2021
Mohamed, A, Menon, H, Chulkina, M, Yee, NS & Pinchuk, IV 2021, 'Drug–microbiota interaction in colon cancer therapy: Impact of antibiotics', Biomedicines, vol. 9, no. 3, 259, pp. 1-13. https://doi.org/10.3390/biomedicines9030259