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Researcher Profile

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Min Yao, MD, MS, PhD

Min Yao, MD, MS, PhD

Professor, Department of Radiation Oncology
Scientific Program:Next-Generation Therapies

Research Interests

  • Radiotherapy
  • Therapeutics
  • Head and Neck Neoplasms
  • Neoplasms
  • Squamous Cell Carcinoma of Head and Neck
  • Radiation
  • Survival
  • Intensity-Modulated Radiotherapy
  • Neck
  • Positron-Emission Tomography
  • Squamous Cell Carcinoma
  • Radiosurgery

Clinical Trials

NRG-GU011: A Phase II Double-Blinded, Placebo-Controlled Trial of PROstate OligoMETastatic RadiotHErapy With or Without ANdrogen Deprivation Therapy in Oligometastatic Prostate Cancer (NRG Promethean)

Recent Publications


Heo, JU, Zhou, F, Jones, R, Zheng, J, Song, X, Qian, P, Baydoun, A, Traughber, MS, Kuo, JW, Helo, RA, Thompson, C, Avril, N, DeVincent, D, Hunt, H, Gupta, A, Faraji, N, Kharouta, MZ, Kardan, A, Bitonte, D, Langmack, CB, Nelson, A, Kruzer, A, Yao, M, Dorth, J, Nakayama, J, Waggoner, SE, Biswas, T, Harris, E, Sandstrom, S, Traughber, BJ & Muzic, RF 2022, 'Abdominopelvic MR to CT registration using a synthetic CT intermediate', Journal of applied clinical medical physics, vol. 23, no. 9, e13731.
Fredman, E, Kharouta, M, Chen, E, Gross, A, Dorth, J, Patel, M, Padula, G & Yao, M 2022, 'Dehydration Reduction in Head and Neck Cancer (DRIHNC) Trial: Daily Oral Fluid and Electrolyte Maintenance to Prevent Acute Care Clinic and Emergency Department Visits for Patients Receiving Radiation for Head and Neck and Esophageal Cancer', Advances in Radiation Oncology, vol. 7, no. 6, 101026.
Muller, RG, Hamill, CS, Vu, B, Thuener, J, Wasman, J, Li, S, Fowler, N, Rezaee, R, Lavertu, P, Yao, M, Burkitt, K, Dorth, J, Teknos, TN, Pan, Q & O'Neill, WQ 2022, 'Impact of AJCC 8th edition staging system and definitive treatment choice on the prognosis of complete responders with p16+ and p16− oropharyngeal squamous cell carcinomas', Oral Oncology, vol. 128, 105861.
Hua, L, Chen, S, Wei, M, Shen, Y, Long, J, Lin, Z, Meng, Y, Guo, C, Huang, H, Tu, X & Yao, M 2022, 'Predictive Value of ERCC1 mRNA Level from Receiver-Operator Characteristic and Pretreatment EBV-DNA Virus Load in Stage II Nasopharyngeal Carcinoma Patients Receiving Intensity-Modulated Radiotherapy with Concurrent Cisplatin', Cancer Biotherapy and Radiopharmaceuticals, vol. 37, no. 1, pp. 2-10.


Sagheer, SH, Bornstein, J, Bar-Ad, V, Cheng, M, Cummins, A, Cognetti, DM, Curry, J, Yao, M, Lavertu, P, Kutler, DI, Zender, C & Luginbuhl, AJ 2021, 'Adjuvant Cesium-131 Brachytherapy for Patients Intolerant of External Beam Radiation Therapy', Laryngoscope, vol. 131, no. 8, pp. E2449-E2451.
Zang, J, Li, Y, Luo, S, Wang, J, Hou, B, Yao, M, Zhao, L & Shi, M 2021, 'Detailed analysis of recovery process of cranial nerve palsy after IMRT-based comprehensive treatment in nasopharyngeal carcinoma', Radiation Oncology, vol. 16, no. 1, 118.
Reddy, P, Yao, M & Patel, M 2021, 'Investigative Landscape in Advanced Non-Melanoma Skin Cancers', Current treatment options in oncology, vol. 22, no. 7, 56.
Liao, W, He, J, Gou, Q, Duan, B, Ai, P, Liu, L, Li, Y, Ren, K, Yao, M & Chen, N 2021, 'Local treatment of metastases plus systemic chemotherapy on overall survival of patients with metastatic nasopharyngeal carcinoma', Head and Neck, vol. 43, no. 8, pp. 2423-2433.
Luginbuhl, A, Calder, A, Kutler, D, Zender, C, Wise-Draper, T, Patel, J, Cheng, M, Karivedu, V, Zhan, T, Parashar, B, Gulati, S, Yao, M, Lavertu, P, Takiar, V, Tang, A, Johnson, J, Keane, W, Curry, J, Cognetti, D & Bar-Ad, V 2021, 'Multi-Institutional Study Validates Safety of Intraoperative Cesium-131 Brachytherapy for Treatment of Recurrent Head and Neck Cancer', Frontiers in Oncology, vol. 11, 786216.
Bauman, JE, Harris, J, Uppaluri, R, Yao, M, Ferris, RL, Chen, J, Jordan, RC, Joshi, NP, Jujjuvaparu, S, Blakaj, DM, Henson, C, Sheqwara, J, Mell, LK, Sen, N, Clump, DA, Garg, MK, Yilmaz, E, Torres-Saavedra, P & Le, QT 2021, 'Nrg-hn003: Phase i and expansion cohort study of adjuvant pembrolizumab, cisplatin and radiation therapy in pathologically high-risk head and neck cancer', Cancers, vol. 13, no. 12, 2882.
Kharouta, M, Zender, C, Podder, T, Rezaee, R, Lavertu, P, Fowler, N, Thuener, J, Li, S, Clancy, K, Xu, Z & Yao, M 2021, 'Permanent Interstitial Cesium-131 Brachytherapy in Treating High-Risk Recurrent Head and Neck Cancer: A Prospective Pilot Study', Frontiers in Oncology, vol. 11, 639480.
Sheikh, S, Kharouta, MZ, Pidikiti, R, Damico, NJ, Choi, S, Dorth, JA, Mansur, DB, Machtay, MX, Yao, M & Bhatt, AD 2022, 'Proton Beam Therapy for Locally Advanced Head and Neck Tumors: An Analysis of Dosimetric and Clinical Outcomes', American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 45, no. 2, pp. 81-87.
Damico, NJ, Wu, AK, Kharouta, MZ, Eitan, T, Pidikiti, R, Jesseph, FB, Smith, M, Langmack, C, Mattson, DL, Dobbins, D, Mansur, DB, Machtay, MX, Dorth, JA, Choi, S, Yao, M & Bhatt, AD 2021, 'Proton beam therapy in the treatment of periorbital malignancies', International Journal of Particle Therapy, vol. 7, no. 4, pp. 42-51.
Yom, SS, Torres-Saavedra, P, Caudell, JJ, Waldron, JN, Gillison, ML, Xia, P, Truong, MT, Kong, C, Jordan, R, Subramaniam, RM, Yao, M, Chung, CH, Geiger, JL, Chan, JW, O'Sullivan, B, Blakaj, DM, Mell, LK, Thorstad, WL, Jones, CU, Banerjee, RN, Lominska, C & Le, QT 2021, 'Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002)', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 39, no. 9, pp. 956-965.
Awan, MJ, Gittleman, H, Barnholtz-Sloan, J, Machtay, M, Nguyen-Tan, PF, Rosenthal, DI, Schultz, C, Huth, BJ, Thorstad, WL, Frank, SJ, Kim, H, Foote, RL, Lango, MN, Shenouda, G, Suntharalingam, M, Harris, J, Zhang, Q, Le, QT & Yao, M 2021, 'Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores – A pooled analysis of RTOG 0129 and 0522', Oral Oncology, vol. 116, 105241.


Sohn, JW, Kim, H, Park, SB, Lee, S, Monroe, JI, Malone, TB, Kinsella, T, Yao, M, Kunos, C, Lo, SS, Shenk, R & Machtay, M 2020, 'Clinical Study of Using Biometrics to Identify Patient and Procedure', Frontiers in Oncology, vol. 10, 586232.
Porceddu, SV, Daniels, C, Yom, SS, Liu, H, Waldron, J, Gregoire, V, Moore, A, Veness, M, Yao, M, Johansen, J, Mehanna, H, Rischin, D & Le, QT 2020, 'Head and Neck Cancer International Group (HNCIG) Consensus Guidelines for the Delivery of Postoperative Radiation Therapy in Complex Cutaneous Squamous Cell Carcinoma of the Head and Neck (cSCCHN)', International Journal of Radiation Oncology Biology Physics, vol. 107, no. 4, pp. 641-651.
Yang, J, Han, J, He, J, Duan, B, Gou, Q, Ai, P, Liu, L, Li, Y, Ren, K, Wang, F, Yao, M & Chen, N 2020, 'Real-World Cost-Effectiveness Analysis of Gemcitabine and Cisplatin Compared to Docetaxel and Cisplatin Plus Fluorouracil Induction Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma', Frontiers in Oncology, vol. 10, 594756.


Ward, MC, Lee, NY, Caudell, JJ, Zajichek, A, Awan, MJ, Koyfman, SA, Dunlap, NE, Zakem, SJ, Hassanzadeh, C, Marcrom, S, Boggs, DH, Isrow, D, Vargo, JA, Heron, DE, Siddiqui, F, Bonner, JA, Beitler, JJ, Yao, M, Trotti, AM & Riaz, N 2019, 'A competing risk nomogram to predict severe late toxicity after modern re-irradiation for squamous carcinoma of the head and neck', Oral Oncology, vol. 90, pp. 80-86.
Chen, X, Zheng, Y, Tatsuoka, C, Muzic, RF, Okoye, CC, O'Donnell, JK, Zidar, D, Avril, N, Oliveira, GH, Liu, H, Bucher, J, Machtay, M, Yao, M & Dorth, JA 2019, 'Chemoradiotherapy-related carotid artery inflammation in head and neck cancer patients quantified by [18F]FDG PET/CT', Oral Oncology, vol. 93, pp. 101-106.
Li, Y, Awan, MJ, Chang, T, Lavertu, P, Zender, C, Rezaee, R, Fowler, N, Wasman, J, Avril, NE, Chen, N, Machtay, M & Yao, M 2019, 'Post-radiotherapy PET/CT for predicting treatment outcomes in head and neck cancer after postoperative radiotherapy', European Journal of Nuclear Medicine and Molecular Imaging, vol. 46, no. 4, pp. 794-800.
Gillison, ML, Trotti, AM, Harris, J, Eisbruch, A, Harari, PM, Adelstein, DJ, Sturgis, EM, Burtness, B, Ridge, JA, Ringash, J, Galvin, J, Yao, M, Koyfman, SA, Blakaj, DM, Razaq, MA, Colevas, AD, Beitler, JJ, Jones, CU, Dunlap, NE, Seaward, SA, Spencer, S, Galloway, TJ, Phan, J, Dignam, JJ & Le, QT 2019, 'Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial', The Lancet, vol. 393, no. 10166, pp. 40-50.