Min Yao, MD, MS, PhD - Penn State Cancer Institute
Researcher Profile
Min Yao, MD, MS, PhD
Professor, Department of Radiation Oncology
Scientific Program:Experimental Therapeutics
Clinical Trials
NRG-CC013: A Randomized, Masked, Placebo Controlled, Phase II Trial Of Concurrent Chemoradiation With Bmx-001 In Patients With Head And Neck Squamous Cell Carcinoma Receiving Concurrent Chemoradiation
Consolidative Use Of Radiotherapy To Block (Curb2) Oligoprogression In Patients With Metastatic Non-Small-Cell Lung Cancer - A Randomized Phase 3 Trial (BR.38)
Long-term Follow-up of AAV2-hAQP1 Gene Therapy in Participants with Radiation-Induced Late Xerostomia- MGT-AQP1-202
NRG-LU008: Phase III Prospective Randomized Trial Of Primary Lung Tumor Stereotactic Body Radiation Therapy Followed By Concurrent Mediastinal Chemoradiation For Locally Advanced Non-Small Cell Lung Cancer
A Pragmatic Randomized Phase III Trial Evaluating Total Ablative Therapy for Patients With Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur) A022101
Recent Publications
2026
Awan, MJ & Yao, M 2026, 'Read Between the (Isodose) Lines', International Journal of Radiation Oncology Biology Physics, vol. 124, no. 1, pp. 96-97. https://doi.org/10.1016/j.ijrobp.2025.08.016
2025
Lorenz, FJ, Kharouta, M, Mahase, SS, Goyal, N, Rezaee, R, Lavertu, P, Machtay, M & Yao, M 2025, 'Hospital-Based Registry Analysis of Staging Efficacy and Proposed Staging Subclassification for Stage I HPV-Associated Oropharyngeal Squamous Cell Carcinoma', Oral Oncology, vol. 163, 107251. https://doi.org/10.1016/j.oraloncology.2025.107251
NRG Oncology RTOG 0920 Collaborating Team 2025, 'Postoperative Radiotherapy ± Cetuximab for Intermediate-Risk Head and Neck Cancer', Journal of Clinical Oncology, vol. 43, no. 12, pp. 1474-1487. https://doi.org/10.1200/JCO-24-01829
Heo, JU, Sun, S, Jones, RS, Gu, Y, Jiang, Y, Qian, P, Baydoun, A, Arsenault, TH, Traughber, M, Helo, RA, Thompson, C, Yao, M, Dorth, J, Nakayama, J, Waggoner, SE, Biswas, T, Harris, E, Sandstrom, SK, Traughber, BJ & Muzic, RF 2025, 'Torso synthetic CT generation by integrating deep learning and segmentation for FDG-PET/MR attenuation correction', Biomedical Physics and Engineering Express, vol. 11, no. 6, 065039. https://doi.org/10.1088/2057-1976/ae13ff
2024
Jin, JY, Yuan, J, Qin, X, Li, Y, Yan, H, Oleinick, NL, Yao, M, Pan, Q, Kong, FM & Machtay, M 2024, 'Derivation of a comprehensive semi-empirical proton RBE model from published experimental cell survival data collected in the PIDE database', Frontiers in Oncology, vol. 14, 1415213. https://doi.org/10.3389/fonc.2024.1415213
Miccio, JA, Potter, NJ, Showkat, A, Yao, M, Mahase, S, Ferenci, M, Sisley, K, Dailey, A, Knipple, J, Blakely, A, Tuanquin, L & Machtay, M 2024, 'Single institution experience of MRI-guided radiotherapy for thoracic tumors and clinical characteristics impacting treatment duty cycle', Frontiers in Oncology, vol. 14, 1401703. https://doi.org/10.3389/fonc.2024.1401703
Kharouta, M, Lorenz, FJ, Mahase, S, Shi, H, Goyal, N & Yao, M 2024, 'The Role of Radiotherapy to the Primary Site in Oropharyngeal Cancer with Limited Metastases—An Analysis of a Hospital-Based Registry', Cancers, vol. 16, no. 24, 4130. https://doi.org/10.3390/cancers16244130
2023
Subramaniam, RM, DeMora, L, Yao, M, Yom, SS, Gillison, M, Caudell, JJ, Waldron, J, Xia, P, Chung, CH, Truong, MT, Echevarria, M, Chan, JW, JGeiger, EL, Mell, L, Seaward, S, Thorstad, WL, Beitler, JJ, Sultanem, K, Blakaj, D & Le, QT 2023, '18F-FDG PET/CT Prediction of Treatment Outcomes in Human Papillomavirus-Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results from NRG-HN002', Journal of Nuclear Medicine, vol. 64, no. 3, pp. 362-367. https://doi.org/10.2967/jnumed.122.264424
Wong, SJ, Torres-Saavedra, PA, Saba, NF, Shenouda, G, Bumpous, JM, Wallace, RE, Chung, CH, El-Naggar, AK, Gwede, CK, Burtness, B, Tennant, PA, Dunlap, NE, Redman, R, Stokes, WA, Rudra, S, Mell, LK, Sacco, AG, Spencer, SA, Nabell, L, Yao, M, Cury, FL, Mitchell, DL, Jones, CU, Firat, S, Contessa, JN, Galloway, T, Currey, A, Harris, J, Curran, WJ & Le, QT 2023, 'Radiotherapy Plus Cisplatin with or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial', JAMA Oncology, vol. 9, no. 11, pp. 1565-1573. https://doi.org/10.1001/jamaoncol.2023.3809
2022
Heo, JU, Zhou, F, Jones, R, Zheng, J, Song, X, Qian, P, Baydoun, A, Traughber, MS, Kuo, JW, Helo, RA, Thompson, C, Avril, N, DeVincent, D, Hunt, H, Gupta, A, Faraji, N, Kharouta, MZ, Kardan, A, Bitonte, D, Langmack, CB, Nelson, A, Kruzer, A, Yao, M, Dorth, J, Nakayama, J, Waggoner, SE, Biswas, T, Harris, E, Sandstrom, S, Traughber, BJ & Muzic, RF 2022, 'Abdominopelvic MR to CT registration using a synthetic CT intermediate', Journal of applied clinical medical physics, vol. 23, no. 9, e13731. https://doi.org/10.1002/acm2.13731
Chen, L, Chen, R, Yao, M, Feng, Z, Yuan, G, Ye, F, Nguyen, K, Karn, J, McComsey, GA, McIntyre, TM & Jin, G 2022, 'COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells', Scientific reports, vol. 12, no. 1, 21779. https://doi.org/10.1038/s41598-022-26457-8
Fredman, E, Kharouta, M, Chen, E, Gross, A, Dorth, J, Patel, M, Padula, G & Yao, M 2022, 'Dehydration Reduction in Head and Neck Cancer (DRIHNC) Trial: Daily Oral Fluid and Electrolyte Maintenance to Prevent Acute Care Clinic and Emergency Department Visits for Patients Receiving Radiation for Head and Neck and Esophageal Cancer', Advances in Radiation Oncology, vol. 7, no. 6, 101026. https://doi.org/10.1016/j.adro.2022.101026
Muller, RG, Hamill, CS, Vu, B, Thuener, J, Wasman, J, Li, S, Fowler, N, Rezaee, R, Lavertu, P, Yao, M, Burkitt, K, Dorth, J, Teknos, TN, Pan, Q & O'Neill, WQ 2022, 'Impact of AJCC 8th edition staging system and definitive treatment choice on the prognosis of complete responders with p16+ and p16− oropharyngeal squamous cell carcinomas', Oral Oncology, vol. 128, 105861. https://doi.org/10.1016/j.oraloncology.2022.105861
Zhang, Z, Wu, B, Peng, G, Xiao, G, Huang, J, Ding, Q, Yang, C, Xiong, X, Ma, H, Shi, L, Yang, J, Hong, X, Wei, J, Qin, Y, Wan, C, Zhong, Y, Zhou, Y, Zhao, X, Leng, Y, Zhang, T, Wu, G, Yao, M, Zhang, X & Yang, K 2022, 'Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial', Clinical Cancer Research, vol. 28, no. 15, pp. 3268-3276. https://doi.org/10.1158/1078-0432.CCR-22-0666
Hua, L, Chen, S, Wei, M, Shen, Y, Long, J, Lin, Z, Meng, Y, Guo, C, Huang, H, Tu, X & Yao, M 2022, 'Predictive Value of ERCC1 mRNA Level from Receiver-Operator Characteristic and Pretreatment EBV-DNA Virus Load in Stage II Nasopharyngeal Carcinoma Patients Receiving Intensity-Modulated Radiotherapy with Concurrent Cisplatin', Cancer Biotherapy and Radiopharmaceuticals, vol. 37, no. 1, pp. 2-10. https://doi.org/10.1089/cbr.2020.4474