Min Yao, MD, MS, PhD - Penn State Cancer Institute
Researcher Profile
Min Yao, MD, MS, PhD
Professor, Department of Radiation Oncology
Scientific Program:Next-Generation Therapies
Research Interests
- Radiotherapy
- Therapeutics
- Head and Neck Neoplasms
- Neoplasms
- Squamous Cell Carcinoma of Head and Neck
- Radiation
- Survival
- Intensity-Modulated Radiotherapy
- Neck
- Positron-Emission Tomography
- Squamous Cell Carcinoma
- Radiosurgery
Clinical Trials
NRG-GU011: A Phase II Double-Blinded, Placebo-Controlled Trial of PROstate OligoMETastatic RadiotHErapy With or Without ANdrogen Deprivation Therapy in Oligometastatic Prostate Cancer (NRG Promethean)
Radiopaque Hydrogel Rectal Spacer for Prostate Cancer Radiation Image Guidance
ACR 3518: Phase I Safety Assessment of Hypofractionated Postoperative Radiotherapy (H-PORT) for Intermediate-Risk Head and Neck Cancer
Recent Publications
2023
Subramaniam, RM, DeMora, L, Yao, M, Yom, SS, Gillison, M, Caudell, JJ, Waldron, J, Xia, P, Chung, CH, Truong, MT, Echevarria, M, Chan, JW, JGeiger, EL, Mell, L, Seaward, S, Thorstad, WL, Beitler, JJ, Sultanem, K, Blakaj, D & Le, QT 2023, '18F-FDG PET/CT Prediction of Treatment Outcomes in Human Papillomavirus-Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results from NRG-HN002', Journal of Nuclear Medicine, vol. 64, no. 3, pp. 362-367. https://doi.org/10.2967/jnumed.122.264424
Wong, SJ, Torres-Saavedra, PA, Saba, NF, Shenouda, G, Bumpous, JM, Wallace, RE, Chung, CH, El-Naggar, AK, Gwede, CK, Burtness, B, Tennant, PA, Dunlap, NE, Redman, R, Stokes, WA, Rudra, S, Mell, LK, Sacco, AG, Spencer, SA, Nabell, L, Yao, M, Cury, FL, Mitchell, DL, Jones, CU, Firat, S, Contessa, JN, Galloway, T, Currey, A, Harris, J, Curran, WJ & Le, QT 2023, 'Radiotherapy Plus Cisplatin with or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial', JAMA Oncology, vol. 9, no. 11, pp. 1565-1573. https://doi.org/10.1001/jamaoncol.2023.3809
2022
Heo, JU, Zhou, F, Jones, R, Zheng, J, Song, X, Qian, P, Baydoun, A, Traughber, MS, Kuo, JW, Helo, RA, Thompson, C, Avril, N, DeVincent, D, Hunt, H, Gupta, A, Faraji, N, Kharouta, MZ, Kardan, A, Bitonte, D, Langmack, CB, Nelson, A, Kruzer, A, Yao, M, Dorth, J, Nakayama, J, Waggoner, SE, Biswas, T, Harris, E, Sandstrom, S, Traughber, BJ & Muzic, RF 2022, 'Abdominopelvic MR to CT registration using a synthetic CT intermediate', Journal of applied clinical medical physics, vol. 23, no. 9, e13731. https://doi.org/10.1002/acm2.13731
Fredman, E, Kharouta, M, Chen, E, Gross, A, Dorth, J, Patel, M, Padula, G & Yao, M 2022, 'Dehydration Reduction in Head and Neck Cancer (DRIHNC) Trial: Daily Oral Fluid and Electrolyte Maintenance to Prevent Acute Care Clinic and Emergency Department Visits for Patients Receiving Radiation for Head and Neck and Esophageal Cancer', Advances in Radiation Oncology, vol. 7, no. 6, 101026. https://doi.org/10.1016/j.adro.2022.101026
Muller, RG, Hamill, CS, Vu, B, Thuener, J, Wasman, J, Li, S, Fowler, N, Rezaee, R, Lavertu, P, Yao, M, Burkitt, K, Dorth, J, Teknos, TN, Pan, Q & O'Neill, WQ 2022, 'Impact of AJCC 8th edition staging system and definitive treatment choice on the prognosis of complete responders with p16+ and p16− oropharyngeal squamous cell carcinomas', Oral Oncology, vol. 128, 105861. https://doi.org/10.1016/j.oraloncology.2022.105861
Hua, L, Chen, S, Wei, M, Shen, Y, Long, J, Lin, Z, Meng, Y, Guo, C, Huang, H, Tu, X & Yao, M 2022, 'Predictive Value of ERCC1 mRNA Level from Receiver-Operator Characteristic and Pretreatment EBV-DNA Virus Load in Stage II Nasopharyngeal Carcinoma Patients Receiving Intensity-Modulated Radiotherapy with Concurrent Cisplatin', Cancer Biotherapy and Radiopharmaceuticals, vol. 37, no. 1, pp. 2-10. https://doi.org/10.1089/cbr.2020.4474
2021
Sagheer, SH, Bornstein, J, Bar-Ad, V, Cheng, M, Cummins, A, Cognetti, DM, Curry, J, Yao, M, Lavertu, P, Kutler, DI, Zender, C & Luginbuhl, AJ 2021, 'Adjuvant Cesium-131 Brachytherapy for Patients Intolerant of External Beam Radiation Therapy', Laryngoscope, vol. 131, no. 8, pp. E2449-E2451. https://doi.org/10.1002/lary.29406
Zang, J, Li, Y, Luo, S, Wang, J, Hou, B, Yao, M, Zhao, L & Shi, M 2021, 'Detailed analysis of recovery process of cranial nerve palsy after IMRT-based comprehensive treatment in nasopharyngeal carcinoma', Radiation Oncology, vol. 16, no. 1, 118. https://doi.org/10.1186/s13014-021-01846-x
Reddy, P, Yao, M & Patel, M 2021, 'Investigative Landscape in Advanced Non-Melanoma Skin Cancers', Current treatment options in oncology, vol. 22, no. 7, 56. https://doi.org/10.1007/s11864-021-00853-0
Liao, W, He, J, Gou, Q, Duan, B, Ai, P, Liu, L, Li, Y, Ren, K, Yao, M & Chen, N 2021, 'Local treatment of metastases plus systemic chemotherapy on overall survival of patients with metastatic nasopharyngeal carcinoma', Head and Neck, vol. 43, no. 8, pp. 2423-2433. https://doi.org/10.1002/hed.26706
Luginbuhl, A, Calder, A, Kutler, D, Zender, C, Wise-Draper, T, Patel, J, Cheng, M, Karivedu, V, Zhan, T, Parashar, B, Gulati, S, Yao, M, Lavertu, P, Takiar, V, Tang, A, Johnson, J, Keane, W, Curry, J, Cognetti, D & Bar-Ad, V 2021, 'Multi-Institutional Study Validates Safety of Intraoperative Cesium-131 Brachytherapy for Treatment of Recurrent Head and Neck Cancer', Frontiers in Oncology, vol. 11, 786216. https://doi.org/10.3389/fonc.2021.786216
Bauman, JE, Harris, J, Uppaluri, R, Yao, M, Ferris, RL, Chen, J, Jordan, RC, Joshi, NP, Jujjuvaparu, S, Blakaj, DM, Henson, C, Sheqwara, J, Mell, LK, Sen, N, Clump, DA, Garg, MK, Yilmaz, E, Torres-Saavedra, P & Le, QT 2021, 'Nrg-hn003: Phase i and expansion cohort study of adjuvant pembrolizumab, cisplatin and radiation therapy in pathologically high-risk head and neck cancer', Cancers, vol. 13, no. 12, 2882. https://doi.org/10.3390/cancers13122882
Kharouta, M, Zender, C, Podder, T, Rezaee, R, Lavertu, P, Fowler, N, Thuener, J, Li, S, Clancy, K, Xu, Z & Yao, M 2021, 'Permanent Interstitial Cesium-131 Brachytherapy in Treating High-Risk Recurrent Head and Neck Cancer: A Prospective Pilot Study', Frontiers in Oncology, vol. 11, 639480. https://doi.org/10.3389/fonc.2021.639480
Sheikh, S, Kharouta, MZ, Pidikiti, R, Damico, NJ, Choi, S, Dorth, JA, Mansur, DB, Machtay, MX, Yao, M & Bhatt, AD 2022, 'Proton Beam Therapy for Locally Advanced Head and Neck Tumors: An Analysis of Dosimetric and Clinical Outcomes', American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 45, no. 2, pp. 81-87. https://doi.org/10.1097/COC.0000000000000883
Damico, NJ, Wu, AK, Kharouta, MZ, Eitan, T, Pidikiti, R, Jesseph, FB, Smith, M, Langmack, C, Mattson, DL, Dobbins, D, Mansur, DB, Machtay, MX, Dorth, JA, Choi, S, Yao, M & Bhatt, AD 2021, 'Proton beam therapy in the treatment of periorbital malignancies', International Journal of Particle Therapy, vol. 7, no. 4, pp. 42-51. https://doi.org/10.14338/IJPT-20-00025.1
Yom, SS, Torres-Saavedra, P, Caudell, JJ, Waldron, JN, Gillison, ML, Xia, P, Truong, MT, Kong, C, Jordan, R, Subramaniam, RM, Yao, M, Chung, CH, Geiger, JL, Chan, JW, O'Sullivan, B, Blakaj, DM, Mell, LK, Thorstad, WL, Jones, CU, Banerjee, RN, Lominska, C & Le, QT 2021, 'Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002)', Journal of Clinical Oncology, vol. 39, no. 9, pp. 956-965. https://doi.org/10.1200/JCO.20.03128
Awan, MJ, Gittleman, H, Barnholtz-Sloan, J, Machtay, M, Nguyen-Tan, PF, Rosenthal, DI, Schultz, C, Huth, BJ, Thorstad, WL, Frank, SJ, Kim, H, Foote, RL, Lango, MN, Shenouda, G, Suntharalingam, M, Harris, J, Zhang, Q, Le, QT & Yao, M 2021, 'Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores – A pooled analysis of RTOG 0129 and 0522', Oral Oncology, vol. 116, 105241. https://doi.org/10.1016/j.oraloncology.2021.105241
2020
Sohn, JW, Kim, H, Park, SB, Lee, S, Monroe, JI, Malone, TB, Kinsella, T, Yao, M, Kunos, C, Lo, SS, Shenk, R & Machtay, M 2020, 'Clinical Study of Using Biometrics to Identify Patient and Procedure', Frontiers in Oncology, vol. 10, 586232. https://doi.org/10.3389/fonc.2020.586232
Porceddu, SV, Daniels, C, Yom, SS, Liu, H, Waldron, J, Gregoire, V, Moore, A, Veness, M, Yao, M, Johansen, J, Mehanna, H, Rischin, D & Le, QT 2020, 'Head and Neck Cancer International Group (HNCIG) Consensus Guidelines for the Delivery of Postoperative Radiation Therapy in Complex Cutaneous Squamous Cell Carcinoma of the Head and Neck (cSCCHN)', International Journal of Radiation Oncology Biology Physics, vol. 107, no. 4, pp. 641-651. https://doi.org/10.1016/j.ijrobp.2020.03.024
Yang, J, Han, J, He, J, Duan, B, Gou, Q, Ai, P, Liu, L, Li, Y, Ren, K, Wang, F, Yao, M & Chen, N 2020, 'Real-World Cost-Effectiveness Analysis of Gemcitabine and Cisplatin Compared to Docetaxel and Cisplatin Plus Fluorouracil Induction Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma', Frontiers in Oncology, vol. 10, 594756. https://doi.org/10.3389/fonc.2020.594756