Researcher Profile

Researcher Profile

Scott H. Medina

Scott H. Medina

Associate Professor, Biomedical Engineering
Scientific Program:Next-Generation Therapies

Research Interests

  • Peptides
  • Neoplasms
  • Liver Neoplasms
  • Hepatocytes
  • Pharmaceutical Preparations
  • Nanoparticles
  • Hydrogels
  • Polysaccharides
  • Dendrimers
  • Membranes
  • Gold
  • Mycobacterium tuberculosis

Recent Publications


Simonson, AW, Umstead, TM, Lawanprasert, A, Klein, B, Almarzooqi, S, Halstead, ES & Medina, SH 2021, 'Extracellular matrix-inspired inhalable aerogels for rapid clearance of pulmonary tuberculosis', Biomaterials, vol. 273, 120848.
Lawanprasert, A, Simonson, AW, Sumner, SE, Nicol, MJ, Pimcharoen, S, Kirimanjeswara, GS & Medina, SH 2022, 'Inhalable SARS-CoV-2 Mimetic Particles Induce Pleiotropic Antigen Presentation', Biomacromolecules, vol. 23, no. 3, pp. 1158-1168.
Sloand, JN, Culp, TE, Wonderling, NM, Gomez, ED & Medina, SH 2021, 'Mechanomorphogenic Films Formed via Interfacial Assembly of Fluorinated Amino Acids', Advanced Functional Materials, vol. 31, no. 40, 2104223.
Simonson, AW, Mongia, AS, Aronson, MR, Alumasa, JN, Chan, DC, Lawanprasert, A, Howe, MD, Bolotsky, A, Mal, TK, George, C, Ebrahimi, A, Baughn, AD, Proctor, EA, Keiler, KC & Medina, SH 2021, 'Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry', Nature Biomedical Engineering, vol. 5, no. 5, pp. 467-480.
Aronson, MR, Medina, SH & Mitchell, MJ 2021, 'Peptide functionalized liposomes for receptor targeted cancer therapy', APL Bioengineering, vol. 5, no. 1, 011501.
Lawanprasert, A, Chau, A, Sloand, JN, Hannifin, S & Medina, SH 2021, 'Tuning the Interfacial Properties of Fluorous Colloids Toward Ultrasound Programmable Bioactivity', ACS Applied Materials and Interfaces, vol. 13, no. 5, pp. 5989-5998.
Sloand, JN, Rokni, E, Watson, CT, Miller, MA, Manning, KB, Simon, JC & Medina, SH 2021, 'Ultrasound-Responsive Nanopeptisomes Enable Synchronous Spatial Imaging and Inhibition of Clot Growth in Deep Vein Thrombosis', Advanced Healthcare Materials, vol. 10, no. 16, 2100520.


Simonson, AW, Aronson, MR, Medina, SH & Medina, SH 2020, 'Antimicrobial Scaffolds', Molecules, vol. 25, no. 12, 2751.
Lawanprasert, A, Guinan, CA, Langford, EA, Hawkins, CE, Sloand, JN, Fescemyer, HW, Aronson, MR, Halle, JA, Marden, JH & Medina, SH 2020, 'Discovery of antitumor lectins from rainforest tree root transcriptomes', PloS one, vol. 15, no. 2, e0229467.
Sloand, JN, Miller, MA & Medina, SH 2021, 'Fluorinated peptide biomaterials', Peptide Science, vol. 113, no. 2, e24184.
Tu, YM, Song, W, Ren, T, Shen, YX, Chowdhury, R, Rajapaksha, P, Culp, TE, Samineni, L, Lang, C, Thokkadam, A, Carson, D, Dai, Y, Mukthar, A, Zhang, M, Parshin, A, Sloand, JN, Medina, SH, Grzelakowski, M, Bhattacharya, D, Phillip, WA, Gomez, ED, Hickey, RJ, Wei, Y & Kumar, M 2020, 'Rapid fabrication of precise high-throughput filters from membrane protein nanosheets', Nature Materials, vol. 19, no. 3, pp. 347-354.
Aronson, MR, Dahl, ES, Halle, JA, Simonson, AW, Gogal, RA, Glick, AB, Aird, KM & Medina, SH 2020, 'Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers', Cellular and Molecular Bioengineering, vol. 13, no. 5, pp. 447-461.
Sloand, JN, Nguyen, TT, Zinck, SA, Cook, EC, Zimudzi, TJ, Showalter, SA, Glick, AB, Simon, JC & Medina, SH 2020, 'Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks', ACS nano, vol. 14, no. 4, pp. 4061-4073.


Medina, SH, Bush, B, Cam, M, Sevcik, E, DelRio, FW, Nandy, K & Schneider, JP 2019, 'Identification of a mechanogenetic link between substrate stiffness and chemotherapeutic response in breast cancer', Biomaterials, vol. 202, pp. 1-11.


Kapur, A, Wang, W, Diaz Hernandez, J, Medina, S, Schneider, JP & Mattoussi, H 2018, Anti-microbial peptide facilitated cytosolic delivery of metallic gold nanomaterials. in WJ Parak, M Osinski & X-J Liang (eds), Colloidal Nanoparticles for Biomedical Applications XIII., 105070R, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10507, SPIE, Colloidal Nanoparticles for Biomedical Applications XIII 2018, San Francisco, United States, 1/27/18.
Simonson, AW, Lawanprasert, A, Goralski, TDP, Keiler, KC & Medina, SH 2019, 'Bioresponsive peptide-polysaccharide nanogels — A versatile delivery system to augment the utility of bioactive cargo', Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 17, pp. 391-400.
Kapur, A, Medina, SH, Wang, W, Palui, G, Ji, X, Schneider, JP & Mattoussi, H 2018, 'Enhanced Uptake of Luminescent Quantum Dots by Live Cells Mediated by a Membrane-Active Peptide', ACS Omega, vol. 3, no. 12, pp. 17164-17172.
Kapur, A, Medina, SH, Wang, W, Palui, G, Schneider, JP & Mattoussi, H 2018, 'Intracellular Delivery of Gold Nanocolloids Promoted by a Chemically Conjugated Anticancer Peptide', ACS Omega, vol. 3, no. 10, pp. 12754-12762.
Aronson, MR, Simonson, AW, Orchard, LM, Llinás, M & Medina, SH 2018, 'Lipopeptisomes: Anticancer peptide-assembled particles for fusolytic oncotherapy', Acta Biomaterialia, vol. 80, pp. 269-277.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)