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Scott H. Medina

Scott H. Medina

Associate Professor, Biomedical Engineering
Scientific Program:Next-Generation Therapies

Research Interests

  • Peptides
  • Neoplasms
  • Membranes
  • Pharmaceutical Preparations
  • Hydrogels
  • Dendrimers
  • Liver Neoplasms
  • Hepatocytes
  • Nanoparticles
  • Thrombosis
  • Polysaccharides
  • Membrane Proteins

Recent Publications


Miller, MA & Medina, S 2024, 'Synthetic Colonic Mucus Enables the Development of Modular Microbiome Organoids', Advanced Functional Materials.


Lawanprasert, A, Sloand, JN, González Vargas, M, Singh, H, Eldor, T, Miller, MA, Pimcharoen, S, Wang, J, Leighow, SM, Pritchard, JR, Dokholyan, NV & Medina, SH 2023, 'Deciphering the Mechanistic Basis for Perfluoroalkyl-Protein Interactions', ChemBioChem, vol. 24, no. 13, e202300159.
Kim, I, Elliott, JC, Lawanprasert, A, Wood, GM, Simon, JC & Medina, SH 2023, 'Real-Time, In Situ Imaging of Macrophages via Phase-Change Peptide Nanoemulsions', Small, vol. 19, no. 46, 2301673.
Guadagno, AH & Medina, SH 2023, 'The manifold role of octapeptide repeats in prion protein assembly', Peptide Science, vol. 115, no. 2, e24303.


Hale, MM & Medina, SH 2022, 'Biomaterials-Enabled Antithrombotics: Recent Advances and Emerging Strategies', Molecular Pharmaceutics, vol. 19, no. 12, pp. 4453-4465.
Lawanprasert, A, Pimcharoen, S, Sumner, SE, Watson, CT, Manning, KB, Kirimanjeswara, GS & Medina, SH 2022, 'Heparin-Peptide Nanogranules for Thrombosis-Actuated Anticoagulation', Small, vol. 18, no. 46, 2203751.
Crowley, NA & Medina, SH 2023, 'Targeted and transient opening of the blood brain barrier in discrete neurocircuits and brain regions', Neuropsychopharmacology, vol. 48, no. 1, pp. 253-254.
Medina, SH 2022, 'Voices in Molecular Pharmaceutics: Meet Dr. Scott Medina, Manipulator of Biomaterial Properties for Precision Therapeutics', Molecular Pharmaceutics, vol. 19, no. 12, pp. 4392.


Simonson, AW, Umstead, TM, Lawanprasert, A, Klein, B, Almarzooqi, S, Halstead, ES & Medina, SH 2021, 'Extracellular matrix-inspired inhalable aerogels for rapid clearance of pulmonary tuberculosis', Biomaterials, vol. 273, 120848.
Lawanprasert, A, Simonson, AW, Sumner, SE, Nicol, MJ, Pimcharoen, S, Kirimanjeswara, GS & Medina, SH 2022, 'Inhalable SARS-CoV-2 Mimetic Particles Induce Pleiotropic Antigen Presentation', Biomacromolecules, vol. 23, no. 3, pp. 1158-1168.
Sloand, JN, Culp, TE, Wonderling, NM, Gomez, ED & Medina, SH 2021, 'Mechanomorphogenic Films Formed via Interfacial Assembly of Fluorinated Amino Acids', Advanced Functional Materials, vol. 31, no. 40, 2104223.
Simonson, AW, Mongia, AS, Aronson, MR, Alumasa, JN, Chan, DC, Lawanprasert, A, Howe, MD, Bolotsky, A, Mal, TK, George, C, Ebrahimi, A, Baughn, AD, Proctor, EA, Keiler, KC & Medina, SH 2021, 'Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry', Nature Biomedical Engineering, vol. 5, no. 5, pp. 467-480.
Aronson, MR, Medina, SH & Mitchell, MJ 2021, 'Peptide functionalized liposomes for receptor targeted cancer therapy', APL Bioengineering, vol. 5, no. 1, 011501.
Lawanprasert, A, Chau, A, Sloand, JN, Hannifin, S & Medina, SH 2021, 'Tuning the Interfacial Properties of Fluorous Colloids Toward Ultrasound Programmable Bioactivity', ACS Applied Materials and Interfaces, vol. 13, no. 5, pp. 5989-5998.
Sloand, JN, Rokni, E, Watson, CT, Miller, MA, Manning, KB, Simon, JC & Medina, SH 2021, 'Ultrasound-Responsive Nanopeptisomes Enable Synchronous Spatial Imaging and Inhibition of Clot Growth in Deep Vein Thrombosis', Advanced Healthcare Materials, vol. 10, no. 16, 2100520.


Simonson, AW, Aronson, MR, Medina, SH & Medina, SH 2020, 'Antimicrobial Scaffolds', Molecules, vol. 25, no. 12, 2751.
Lawanprasert, A, Guinan, CA, Langford, EA, Hawkins, CE, Sloand, JN, Fescemyer, HW, Aronson, MR, Halle, JA, Marden, JH & Medina, SH 2020, 'Discovery of antitumor lectins from rainforest tree root transcriptomes', PloS one, vol. 15, no. 2, e0229467.
Sloand, JN, Miller, MA & Medina, SH 2021, 'Fluorinated peptide biomaterials', Peptide Science, vol. 113, no. 2, e24184.
Tu, YM, Song, W, Ren, T, Shen, YX, Chowdhury, R, Rajapaksha, P, Culp, TE, Samineni, L, Lang, C, Thokkadam, A, Carson, D, Dai, Y, Mukthar, A, Zhang, M, Parshin, A, Sloand, JN, Medina, SH, Grzelakowski, M, Bhattacharya, D, Phillip, WA, Gomez, ED, Hickey, RJ, Wei, Y & Kumar, M 2020, 'Rapid fabrication of precise high-throughput filters from membrane protein nanosheets', Nature Materials, vol. 19, no. 3, pp. 347-354.
Aronson, MR, Dahl, ES, Halle, JA, Simonson, AW, Gogal, RA, Glick, AB, Aird, KM & Medina, SH 2020, 'Re-engineering Antimicrobial Peptides into Oncolytics Targeting Drug-Resistant Ovarian Cancers', Cellular and Molecular Bioengineering, vol. 13, no. 5, pp. 447-461.
Sloand, JN, Nguyen, TT, Zinck, SA, Cook, EC, Zimudzi, TJ, Showalter, SA, Glick, AB, Simon, JC & Medina, SH 2020, 'Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks', ACS nano, vol. 14, no. 4, pp. 4061-4073.