Researcher Profile

Researcher Profile

Reka Z. Albert, PhD

Reka Z. Albert, PhD

Distinguished Professor, Physics
Scientific Program:Next-Generation Therapies
rza1@psu.edu

Research Interests

  • Signal Transduction
  • Proteins
  • Genes
  • Abscisic Acid
  • Gene Regulatory Networks
  • T-Lymphocytes
  • Neoplasms
  • Large Granular Lymphocytic Leukemia
  • Kinetics
  • Gene Expression
  • Theoretical Models
  • Systems Biology

Recent Publications

2020

Yan, G, Arenas, A & Albert, R 2020, 'Introduction to the Special Section on Network Science in Biological and Bio-Inspired Systems', IEEE Transactions on Network Science and Engineering, vol. 7, no. 1, 9025278, pp. 409-410. https://doi.org/10.1109/TNSE.2019.2961198

2019

Deritei, D, Rozum, J, Ravasz Regan, E & Albert, R 2019, 'A feedback loop of conditionally stable circuits drives the cell cycle from checkpoint to checkpoint', Scientific reports, vol. 9, no. 1, 16430. https://doi.org/10.1038/s41598-019-52725-1
Yahyanejad, F, Albert, R & DasGupta, B 2019, 'A survey of some tensor analysis techniques for biological systems', Quantitative Biology, vol. 7, no. 4, pp. 266-277. https://doi.org/10.1007/s40484-019-0186-5
Rozum, JC & Albert, R 2019, 'CONTROLLING the CELL CYCLE RESTRICTION SWITCH ACROSS the INFORMATION GRADIENT', Advances in Complex Systems, vol. 22, no. 7-8, 1950020. https://doi.org/10.1142/S0219525919500206
Campbell, C & Albert, R 2019, 'Edgetic perturbations to eliminate fixed-point attractors in Boolean regulatory networks', Chaos, vol. 29, no. 2, 023130. https://doi.org/10.1063/1.5083060
Russo, L, Albert, R, Campbell, C & Shea, K 2019, 'Experimental species introduction shapes network interactions in a plant-pollinator community', Biological Invasions, vol. 21, no. 12, pp. 3505-3519. https://doi.org/10.1007/s10530-019-02064-z
Maheshwari, P, Du, H, Sheen, J, Assmann, SM & Albert, R 2019, 'Model-driven discovery of calcium-related protein-phosphatase inhibition in plant guard cell signaling', PLoS computational biology, vol. 15, no. 10, e1007429. https://doi.org/10.1371/journal.pcbi.1007429
Wooten, DJ, Groves, SM, Tyson, DR, Liu, Q, Lim, JS, Albert, R, Lopez, CF, Sage, J & Quaranta, V 2019, 'Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers', PLoS computational biology, vol. 15, no. 10, pp. e1007343. https://doi.org/10.1371/journal.pcbi.1007343
Gómez Tejeda Zañudo, J, Guinn, MT, Farquhar, K, Szenk, M, Steinway, SN, Balázsi, G & Albert, R 2019, 'Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition', Physical Biology, vol. 16, no. 3, 031002. https://doi.org/10.1088/1478-3975/aaffa1

2018

G.T. Zañudo, J, Steinway, SN & Albert, R 2018, 'Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer', Current Opinion in Systems Biology, vol. 9, pp. 1-10. https://doi.org/10.1016/j.coisb.2018.02.002
Gan, X & Albert, R 2018, 'General method to find the attractors of discrete dynamic models of biological systems', Physical Review E, vol. 97, no. 4, 042308. https://doi.org/10.1103/PhysRevE.97.042308
Rozum, JC & Albert, R 2018, 'Identifying (un)controllable dynamical behavior in complex networks', PLoS computational biology, vol. 14, no. 12, e1006630. https://doi.org/10.1371/journal.pcbi.1006630
Albert, RZ, Baillieul, J & Motter, AE 2018, 'Introduction to the Special Issue on Approaches to Control Biological and Biologically Inspired Networks', IEEE Transactions on Control of Network Systems, vol. 5, no. 2, pp. 690-693. https://doi.org/10.1109/TCNS.2018.2836303
Rozum, JC & Albert, RZ 2018, 'Self-sustaining positive feedback loops in discrete and continuous systems', Journal of Theoretical Biology, vol. 459, pp. 36-44. https://doi.org/10.1016/j.jtbi.2018.09.017
Yang, G, Zañudo, JGT & Albert, R 2018, 'Target control in logical models using the domain of influence of nodes', Frontiers in Physiology, vol. 9, no. MAY, 454. https://doi.org/10.3389/fphys.2018.00454

2017

Maheshwari, P & Albert, R 2017, 'A framework to find the logic backbone of a biological network', BMC systems biology, vol. 11, no. 1. https://doi.org/10.1186/s12918-017-0482-5
Albert, R, Acharya, BR, Jeon, BW, Zañudo, JGT, Zhu, M, Osman, K & Assmann, SM 2017, 'A new discrete dynamic model of ABA-induced stomatal closure predicts key feedback loops', PLoS biology, vol. 15, no. 9, e2003451. https://doi.org/10.1371/journal.pbio.2003451
Campbell, C, Aucott, S, Ruths, J, Ruths, D, Shea, K & Albert, R 2017, 'Correlations in the degeneracy of structurally controllable topologies for networks', Scientific reports, vol. 7, 46251. https://doi.org/10.1038/srep46251
Zañudo, JGT, Yang, G, Albert, R & Levine, H 2017, 'Structure-based control of complex networks with nonlinear dynamics', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 28, pp. 7234-7239. https://doi.org/10.1073/pnas.1617387114

2016

Gan, X & Albert, R 2016, 'Analysis of a dynamic model of guard cell signaling reveals the stability of signal propagation', BMC systems biology, vol. 10, no. 1, 78. https://doi.org/10.1186/s12918-016-0327-7
Yang, G, Campbell, C & Albert, R 2016, 'Compensatory interactions to stabilize multiple steady states or mitigate the effects of multiple deregulations in biological networks', Physical Review E, vol. 94, no. 6, 062316. https://doi.org/10.1103/PhysRevE.94.062316
Steinway, SN, Wang, RS & Albert, R 2016, Discrete dynamic modeling: A network approach for systems pharmacology. in AAPS Advances in the Pharmaceutical Sciences Series. AAPS Advances in the Pharmaceutical Sciences Series, vol. 23, Springer Verlag, pp. 81-103. https://doi.org/10.1007/978-3-319-44534-2_5
Sun, Z & Albert, R 2016, 'Node-independent elementary signaling modes: A measure of redundancy in Boolean signaling transduction networks', Network Science, vol. 4, no. 3, pp. 273-292. https://doi.org/10.1017/nws.2016.4
Campbell, C, Russo, L, Marins, A, DeSouza, O, Schönrogge, K, Mortensen, D, Tooker, J, Albert, R & Shea, K 2016, 'Top-down network analysis characterizes hidden termite–termite interactions', Ecology and Evolution, vol. 6, no. 17, pp. 6178-6188. https://doi.org/10.1002/ece3.2313

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