Researcher Profile

Researcher Profile

Reka Z. Albert, PhD

Reka Z. Albert, PhD

Distinguished Professor, Physics
Scientific Program:Experimental Therapeutics
rza1@psu.edu

Research Interests

  • Signal Transduction
  • Proteins
  • Genes
  • Gene Regulatory Networks
  • Abscisic Acid
  • T-Lymphocytes
  • Large Granular Lymphocytic Leukemia
  • Therapeutics
  • Gene Expression
  • Theoretical Models
  • Systems Biology
  • Arabidopsis

Recent Publications

2019

Campbell, C & Albert, RZ 2019, 'Edgetic perturbations to eliminate fixed-point attractors in Boolean regulatory networks', Chaos, vol. 29, no. 2, 023130. https://doi.org/10.1063/1.5083060
Russo, L, Albert, RZ, Campbell, C & Shea, K 2019, 'Experimental species introduction shapes network interactions in a plant-pollinator community', Biological Invasions. https://doi.org/10.1007/s10530-019-02064-z
Gómez Tejeda Zañudo, J, Guinn, MT, Farquhar, K, Szenk, M, Steinway, SN, Balázsi, G & Albert, RZ 2019, 'Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition', Physical Biology, vol. 16, no. 3, 031002. https://doi.org/10.1088/1478-3975/aaffa1

2018

G.T. Zañudo, J, Steinway, SN & Albert, RZ 2018, 'Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer', Current Opinion in Systems Biology, vol. 9, pp. 1-10. https://doi.org/10.1016/j.coisb.2018.02.002
Gan, X & Albert, RZ 2018, 'General method to find the attractors of discrete dynamic models of biological systems', Physical Review E, vol. 97, no. 4, 042308. https://doi.org/10.1103/PhysRevE.97.042308
Rozum, JC & Albert, RZ 2018, 'Identifying (un)controllable dynamical behavior in complex networks', PLoS computational biology, vol. 14, no. 12, e1006630. https://doi.org/10.1371/journal.pcbi.1006630
Albert, RZ, Baillieul, J & Motter, AE 2018, 'Introduction to the Special Issue on Approaches to Control Biological and Biologically Inspired Networks', IEEE Transactions on Control of Network Systems, vol. 5, no. 2, pp. 690-693. https://doi.org/10.1109/TCNS.2018.2836303
Rozum, JC & Albert, RZ 2018, 'Self-sustaining positive feedback loops in discrete and continuous systems', Journal of Theoretical Biology, vol. 459, pp. 36-44. https://doi.org/10.1016/j.jtbi.2018.09.017
Yang, G, Zañudo, JGT & Albert, RZ 2018, 'Target control in logical models using the domain of influence of nodes', Frontiers in Physiology, vol. 9, no. MAY, 454. https://doi.org/10.3389/fphys.2018.00454

2017

Maheshwari, P & Albert, RZ 2017, 'A framework to find the logic backbone of a biological network', BMC systems biology, vol. 11, no. 1. https://doi.org/10.1186/s12918-017-0482-5
Albert, RZ, Acharya, BR, Jeon, BW, Zañudo, JGT, Zhu, M, Osman, K & Assmann, SM 2017, 'A new discrete dynamic model of ABA-induced stomatal closure predicts key feedback loops', PLoS Biology, vol. 15, no. 9, e2003451. https://doi.org/10.1371/journal.pbio.2003451
Campbell, C, Aucott, S, Ruths, J, Ruths, D, Shea, K & Albert, RZ 2017, 'Correlations in the degeneracy of structurally controllable topologies for networks', Scientific reports, vol. 7, 46251. https://doi.org/10.1038/srep46251
Zañudo, JGT, Yang, G, Albert, RZ & Levine, H 2017, 'Structure-based control of complex networks with nonlinear dynamics', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 28, pp. 7234-7239. https://doi.org/10.1073/pnas.1617387114

2016

Gan, X & Albert, RZ 2016, 'Analysis of a dynamic model of guard cell signaling reveals the stability of signal propagation', BMC systems biology, vol. 10, no. 1, 78. https://doi.org/10.1186/s12918-016-0327-7
Yang, G, Campbell, C & Albert, RZ 2016, 'Compensatory interactions to stabilize multiple steady states or mitigate the effects of multiple deregulations in biological networks', Physical Review E, vol. 94, no. 6, 062316. https://doi.org/10.1103/PhysRevE.94.062316
Sun, Z & Albert, RZ 2016, 'Node-independent elementary signaling modes: A measure of redundancy in Boolean signaling transduction networks', Network Science, vol. 4, no. 3, pp. 273-292. https://doi.org/10.1017/nws.2016.4
Campbell, C, Russo, L, Marins, A, DeSouza, O, Schönrogge, K, Mortensen, D, Tooker, JF, Albert, RZ & Shea, K 2016, 'Top-down network analysis characterizes hidden termite–termite interactions', Ecology and Evolution, vol. 6, no. 17, pp. 6178-6188. https://doi.org/10.1002/ece3.2313

2015

Rajtmajer, S, Roy, A, Albert, RZ, Molenaar, P & Hillary, FG 2015, 'A voxelwise approach to determine consensus regions-of-interest for the study of brain network plasticity', Frontiers in Neuroanatomy, vol. 9, no. JULY, 97. https://doi.org/10.3389/fnana.2015.00097
Zañudo, JGT & Albert, RZ 2015, 'Cell Fate Reprogramming by Control of Intracellular Network Dynamics', PLoS computational biology, vol. 11, no. 4, e1004193. https://doi.org/10.1371/journal.pcbi.1004193
Steinway, SN, Zañudo, JGT, Michel, PJ, Feith, DJ, Loughran, TP & Albert, RZ 2015, 'Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes', npj Systems Biology and Applications, vol. 1, 15014. https://doi.org/10.1038/npjsba.2015.14
Naldi, A, Monteiro, PT, Müssel, C, Kestler, HA, Thieffry, D, Xenarios, I, Saez-Rodriguez, J, Helikar, T, Chaouiya, C, Albert, RZ, Barberis, M, Calzone, L, Chasapi, A, Cokelaer, T, Crespo, I, Dorier, J, Dräger, A, Hernandez, C, Hucka, M, De Jong, H, Keating, SM, Klamt, S, Klarner, H, Laubenbacher, R, Le Novère, N, Niknejad, A, Rodriguez, N, Siebert, H, Stoll, G & Zañudo., JGT 2015, 'Cooperative development of logical modelling standards and tools with CoLoMoTo', Bioinformatics, vol. 31, no. 7, pp. 1154-1159. https://doi.org/10.1093/bioinformatics/btv013
Steinway, SN, Biggs, MB, Loughran, TP, Papin, JA & Albert, RZ 2015, 'Inference of Network Dynamics and Metabolic Interactions in the Gut Microbiome', PLoS computational biology, vol. 11, no. 6, e1004338. https://doi.org/10.1371/journal.pcbi.1004338
Campbell, C, Yang, S, Albert, RZ & Shea, K 2015, 'Plant-pollinator community network response to species invasion depends on both invader and community characteristics', Oikos, vol. 124, no. 4, pp. 406-413. https://doi.org/10.1111/oik.02039
Albert, RZ & Robeva, R 2015, Signaling Networks: Asynchronous Boolean Models. in Algebraic and Discrete Mathematical Methods for Modern Biology. Elsevier, pp. 65-91. https://doi.org/10.1016/B978-0-12-801213-0.00004-6
Campbell, C, Ruths, J, Ruths, D, Shea, K & Albert, RZ 2015, 'Topological constraints on network control profiles', Scientific reports, vol. 5, 18693. https://doi.org/10.1038/srep18693

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