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Researcher Profile

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Reka Z. Albert, PhD

Reka Z. Albert, PhD

Distinguished Professor, Physics
Center for Infectious Disease Dynamics
Scientific Program:Next-Generation Therapies

Research Interests

  • Signal Transduction
  • Genes
  • Proteins
  • Gene Regulatory Networks
  • Abscisic Acid
  • Neoplasms
  • T-Lymphocytes
  • Large Granular Lymphocytic Leukemia
  • Gene Expression
  • Theoretical Models
  • Systems Biology
  • Bacteria

Recent Publications


Gan, X, Sengottaiyan, P, Park, KH, Assmann, SM & Albert, RZ 2024, 'A network-based modeling framework reveals the core signal transduction network underlying high carbon dioxide-induced stomatal closure in guard cells', PLoS biology, vol. 22, no. 5 May, e3002592.


Li, R, Rozum, JC, Quail, MM, Qasim, MN, Sindi, SS, Nobile, CJ, Albert, R & Hernday, AD 2023, 'Inferring gene regulatory networks using transcriptional profiles as dynamical attractors', PLoS computational biology, vol. 19, no. 8 August, e1010991.
Gan, X, Shu, Z, Wang, X, Yan, D, Li, J, Ofaim, S, Albert, R, Li, X, Liu, B, Zhou, X & Barabási, AL 2023, 'Network medicine framework reveals generic herb-symptom effectiveness of traditional Chinese medicine', Science Advances, vol. 9, no. 43, eadh0215.
Fatemi Nasrollahi, FS, Campbell, C & Albert, R 2023, 'Predicting cascading extinctions and efficient restoration strategies in plant–pollinator networks via generalized positive feedback loops', Scientific reports, vol. 13, no. 1, 902.
Newby, E, Zañudo, JGT & Albert, R 2023, 'Structure-based approach to identify driver nodes in ensembles of biologically inspired Boolean networks', Physical Review Research, vol. 5, no. 3, 033009.


Maheshwari, P, Assmann, SM & Albert, R 2022, 'Inference of a Boolean Network From Causal Logic Implications', Frontiers in Genetics, vol. 13, 836856.
Rozum, J & Albert, R 2022, 'Leveraging network structure in nonlinear control', NPJ systems biology and applications, vol. 8, no. 1, 36.
Rozum, JC, Deritei, D, Park, KH, Zañudo, JGT & Albert, R 2022, 'Pystablemotifs: Python library for attractor identification and control in Boolean networks', Bioinformatics, vol. 38, no. 5, pp. 1465-1466.
Newby, E, Tejeda Zanudo, JG & Albert, R 2022, 'Structure-based approach to identifying small sets of driver nodes in biological networks', Chaos, vol. 32, no. 6, 063102.
Campbell, C, Russo, L, Albert, R, Buckling, A & Shea, K 2022, 'Whole community invasions and the integration of novel ecosystems', PLoS computational biology, vol. 18, no. 6, e1010151.


Zañudo, JGT, Mao, P, Alcon, C, Kowalski, K, Johnson, GN, Xu, G, Baselga, J, Scaltriti, M, Letai, A, Montero, J, Albert, R & Wagle, N 2021, 'Cell line-specific network models of er breast cancer identify potential pi3kainhibitor resistance mechanisms and drug combinations', Cancer Research, vol. 81, no. 17, pp. 4603-4617.
Mony, VK, Drangowska-Way, A, Albert, R, Harrison, E, Ghaddar, A, Horak, MK, Ke, W & O’Rourke, EJ 2021, 'Context-specific regulation of lysosomal lipolysis through network-level diverting of transcription factor interactions', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 41, e2104832118.
Wooten, DJ, Gebru, M, Wang, HG & Albert, R 2021, 'Data-driven math model of FLT3-ITD acute myeloid leukemia reveals potential therapeutic targets', Journal of Personalized Medicine, vol. 11, no. 3, 193.
Chatterjee, T, Albert, R, Thapliyal, S, Azarhooshang, N & DasGupta, B 2021, 'Detecting network anomalies using Forman–Ricci curvature and a case study for human brain networks', Scientific reports, vol. 11, no. 1, 8121.
Alcon, C, Zañudo, JGT, Albert, R, Wagle, N, Scaltriti, M, Letai, A, Samitier, J & Montero, J 2021, 'Er+ breast cancer strongly depends on mcl-1 and bcl-xl anti-apoptotic proteins', Cells, vol. 10, no. 7, 1659.
Wooten, DJ, Zañudo, JGT, Murrugarra, D, Perry, AM, Dongari-Bagtzoglou, A, Laubenbacher, R, Nobile, CJ & Albert, R 2021, 'Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies', PLoS computational biology, vol. 17, no. 3, e1008690.
Rozum, JC, Zañudo, JGT, Gan, X, Deritei, D & Albert, R 2021, 'Parity and time reversal elucidate both decision-making in empirical models and attractor scaling in critical Boolean networks', Science Advances, vol. 7, no. 29, eabf8124.
Fatemi Nasrollahi, FS, Gómez Tejeda Zañudo, J, Campbell, C & Albert, R 2021, 'Relationships among generalized positive feedback loops determine possible community outcomes in plant-pollinator interaction networks', Physical Review E, vol. 104, no. 5, 054304.
Wooten, DJ & Albert, R 2021, 'Synergy: A Python library for calculating, analyzing and visualizing drug combination synergy', Bioinformatics, vol. 37, no. 10, pp. 1473-1474.


Maheshwari, P, Assmann, SM & Albert, R 2020, 'A Guard Cell Abscisic Acid (ABA) Network Model That Captures the Stomatal Resting State', Frontiers in Physiology, vol. 11, 927.
Yan, G, Arenas, A & Albert, R 2020, 'Introduction to the Special Section on Network Science in Biological and Bio-Inspired Systems', IEEE Transactions on Network Science and Engineering, vol. 7, no. 1, 9025278, pp. 409-410.
Maheshwari, P & Albert, R 2020, 'Network model and analysis of the spread of Covid-19 with social distancing', Applied Network Science, vol. 5, no. 1, 100.