Seyed Alireza Mansouri, MD - Penn State Cancer Institute
Researcher Profile
Seyed Alireza Mansouri, MD
Associate Professor, Department of Neurosurgery
Penn State Neuroscience Institute
Penn State Neuroscience Institute
Scientific Program:Experimental Therapeutics
Clinical Trials
Integration of CSF proteogenomics in the diagnosis and management of diffuse gliomas
Prospective proteogenomic analysis of CNS tumors
Recent Publications
2026
Gerritsen, JKW, Karschnia, P, Bello, L, Hervey-Jumper, S, Young, JS, Seidel, K, Satoer, DD, Schnell, O, Parsons, M, Nahed, BV, Menna, G, Teske, N, Ashkan, K, Barberis, M, Bettegowda, C, Boele, F, Byrne, RW, Cahill, DP, Delev, D, De Witte, E, Drummond, K, Duerinck, J, Dunn, G, Emerson, S, Esquenazi, Y, Freyschlag, CF, Geurts, M, Grossman, R, Hadjipanayis, CG, Jensdottir, M, Klimek, M, Lee, C, Maguire, A, Mansouri, A, Markert, JM, Narita, Y, Olivi, A, Pallud, J, Piil, K, Preusser, M, Quinones-Hinojosa, A, Skjøth-Rasmussen, J, Sabel, M, Senft, C, Short, S, Solheim, OS, Stummer, W, Szelényi, A, Vik-Mo, EO, Watts, C, Weller, M, Wen, P, Smith, TR, Sanai, N, Krieg, SM, Schucht, P, Broekman, MLD, De Vleeschouwer, S, Jakola, AS, van den Bent, MJ, Chang, SM, Vogelbaum, MA, Vincent, AJPE, Tonn, JC & Berger, MS 2026, 'A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 1: intraoperative recommendations for mapping, monitoring, and decision making', The Lancet Oncology, vol. 27, no. 1, pp. e11-e23. https://doi.org/10.1016/S1470-2045(25)00531-5
Gerritsen, JKW, Karschnia, P, Bello, L, Hervey-Jumper, S, Young, JS, Seidel, K, Satoer, DD, Schnell, O, Parsons, M, Nahed, BV, Menna, G, Teske, N, Ashkan, K, Barberis, M, Bettegowda, C, Boele, F, Byrne, RW, Cahill, DP, Delev, D, De Witte, E, Drummond, K, Duerinck, J, Dunn, G, Emerson, S, Esquenazi, Y, Freyschlag, CF, Geurts, M, Grossman, R, Hadjipanayis, CG, Jensdottir, M, Klimek, M, Lee, C, Maguire, A, Mansouri, A, Markert, JM, Narita, Y, Olivi, A, Pallud, J, Piil, K, Preusser, M, Quinones-Hinojosa, A, Skjøth-Rasmussen, J, Sabel, M, Senft, C, Short, S, Solheim, OS, Stummer, W, Szelényi, A, Vik-Mo, EO, Watts, C, Weller, M, Wen, P, Smith, TR, Sanai, N, Krieg, SM, Schucht, P, Broekman, MLD, De Vleeschouwer, S, Jakola, AS, van den Bent, MJ, Chang, SM, Vogelbaum, MA, Vincent, AJPE, Tonn, JC & Berger, MS 2026, 'A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 2: perioperative recommendations for neurological, language, functional, and quality-of-life assessment', The Lancet Oncology, vol. 27, no. 1, pp. e24-e32. https://doi.org/10.1016/S1470-2045(25)00532-7
Landry, AP, Wang, JZ, Patil, V, Ajisebutu, A, Gui, C, Yefet, LS, Ellenbogen, Y, Liu, J, Mamatjan, Y, Wei, Q, Singh, O, Mansouri, S, Ehret, F, Capper, D, Cohen-Gadol, AA, Tabatabai, G, Tatagiba, M, Behling, F, Barnholtz-Sloan, JS, Sloan, AE, Chambless, LB, Mansouri, A, Makarenko, S, Yip, S, Tsang, DS, Gao, A, Aldape, K, Nassiri, F, Zadeh, G, Santarius, T, Selman, W, Couce, M, Sloan, AE, Brastianos, PK, Shih, HA, Linda Bi, W, Huang, RY, Wen, PY, Walbert, T, Lee, I, Felicella, M, Brodie, C, Malta, T, Castro, AVC, Noushmehr, H, Snyder, J, Dimeco, F, Saladino, A, Pollo, B, Schichor, C, Tonn, JC, Kaufmann, TJ, Lachance, D, Giannini, C, Galanis, E, Raghunathan, A, Hanemann, CO, Au, K, Goldbrunner, R, Galldiks, N, Timmer, M, Ole Schimdt, N, Herold-Mende, C, Sahm, F, Jungk, C, Jungwirth, G, Von Deimling, A, Jenkinson, MD, Millward, CP, Islim, AI, Drummond, K, Morokoff, A, Tabatabai, G, Behling, F, Renovanz, M, Tatagiba, M, Santacroce, A, La Fougere, C, Schittenhelm, J, Raleigh, DR, Perry, A, Butowski, N, Westphal, M, Lamszus, K, Ricklefs, F, Mawrin, C, Horbinski, CM, Ng, HK, Snuderl, M, Kurz, S, Sulman, EP, Zada, G, Cohen-Gadol, A, Yip, S, Makarenko, S, Zherebitskiy, V, Hnenny, L, Dunn, IF, Moliterno, J, McDermott, MW, Vogelbaum, M, Javadpour, M, Fountain, D, Mathiesen, TI, Aldape, K, Barnholtz-Sloan, J, Pathmanaban, O, Boutros, PC, Alkividias, T, Fountas, KN, Walsh, KM, Short, SC, Carvalho, B, Maas, SLN, Bos, EM, Dincer, A, Kurz, S, Passlack, P, Deng, M, Ehret, F, Mehta, MP, Odia, Y, Everson, R, Balogun, JA, Lopez, C, Calabrese, E, Karschnia, P, Teske, N, Fariselli, L, Greve, T, Arvaniti, C, Benjamin, C, Ivan, M, Jackson, C, Jeyaretna, S, Scartoni, D, Amelio, D, Palmer, J, Ivanidze, J, Ostrom, Q, Trung Kien, D, Youngblood, M, Millareschavez, M, Althgafi, M, Emerson, S, Weller, M, Lerhun, E, Martínez-Pérez, R, Smee, R, Mukherjee, R, Cervio, A, Turner, C, Muirhead, W, Molina, ES, Julius, V, Chen, J, Karmur, B, Mrugala, M & Neth, B 2026, 'A framework for using DNA methylation-based modelling for the clinical management of cranial meningioma', Neuro-oncology, vol. 28, no. 2, pp. 430-439. https://doi.org/10.1093/neuonc/noaf237
Yefet, LS, Landry, AP, Wang, JZ, Liu, J, Patil, V, Gui, C, Ajisebutu, A, Ellenbogen, Y, Mamatjan, Y, Yakubov, R, Kaloti, R, Persaud, P, Wei, Q, Singh, O, Mansouri, S, Bunda, S, Cohen-Gadol, AA, Tabatabai, G, Tatagiba, M, Behling, F, Barnholtz-Sloan, JS, Sloan, AE, Chotai, S, Chambless, LB, Mansouri, A, Agnihotri, S, Makarenko, S, Yip, S, Tsang, DS, Aldape, K, Gao, A, Nassiri, F & Zadeh, G 2026, 'Assessment of molecular tools in pediatric, adolescent, and young adult meningioma highlights the need for lifespan precision in neuro-oncology', Neuro-oncology, vol. 28, no. 3, pp. 765-775. https://doi.org/10.1093/neuonc/noaf252
Mohtat, A, Moraes, FY, Mansouri, A & Gotian, R 2026, 'Comparing traditional and AI-enhanced mentorship for leadership development in medicine', Clinics, vol. 81, 100956. https://doi.org/10.1016/j.clinsp.2026.100956
Kihlstedt, CJ, Dénes, A, Mansouri, A, Mikolajewicz, N, Skoglund, T, Köster, L, Corell, A, Carén, H, Ferreyra Vega, S, Olsson Bontell, T, Thorsell, A & Jakola, AS 2026, 'Proteomics in IDH-mutated diffuse lower-grade glioma: A scoping review', Neuro-Oncology Advances, vol. 8, no. 1, vdaf258. https://doi.org/10.1093/noajnl/vdaf258
2025
Bhanja, D, Zhu, J, Wilding, H, Benavides-Vasquez, J, de Macedo Filho, L, Ozair, A, Moeckel, C, Badani, A, Hong, J, Sivik, J, Drabick, JJ, Pameijer, CR, Margolin, K, Ahluwalia, M & Mansouri, A 2025, 'A Population-Level Real-World Analysis and Single-Center Validation of Melanoma Brain Metastasis Epidemiology following Dual-Agent Immunotherapy', Clinical Cancer Research, vol. 31, no. 15, pp. 3276-3284. https://doi.org/10.1158/1078-0432.CCR-24-2681
Riviere-Cazaux, C, Keough, MB, Zuccato, JA, Kumar, R, Schulz, S, Warrington, AE, Ruff, MW, Ellingson, BM, Sanai, N, Campian, JL, Kizilbash, SH, Parney, IF, Zadeh, G, Khasraw, M, Kessler, T, Sener, U, Cahill, DP, Mansouri, A & Burns, TC 2025, 'A hitchhiker's guide to cerebrospinal fluid biomarkers for neuro-oncology', Neuro-oncology, vol. 27, no. 5, pp. 1165-1179. https://doi.org/10.1093/neuonc/noae276
Wilding, H, Mikolajewicz, N, Bhanja, D, Moeckel, C, Ozair, A, de Macedo Filho, L, Tuohy, K, Hamidi, N, Trifoi, M, Snyder, B, Kuechenmeister, B, Salmanian, S, Ahluwalia, M & Mansouri, A 2025, 'A nomogram to predict development of brain metastasis in non-small cell lung cancer patients: a retrospective analysis using routinely available medical records', The Lancet Regional Health - Americas, vol. 50, 101213. https://doi.org/10.1016/j.lana.2025.101213
Harba, D, Corell, A, Mansouri, A, Brandal, P, Blomstrand, M & Jakola, AS 2025, 'A scoping review of proton radiation therapy and mutant-isocitrate dehydrogenase-inhibitors in IDH mutated lower-grade gliomas: pushing beyond surrogate end-points', Acta Neurochirurgica, vol. 167, no. 1, 196. https://doi.org/10.1007/s00701-025-06612-6
Badani, A, de Moraes, FY, Vollmuth, P, Chung, C & Mansouri, A 2025, 'AI and innovation in clinical trials', npj Digital Medicine, vol. 8, no. 1, 683. https://doi.org/10.1038/s41746-025-02048-5
Shenoy, G, Sahu, A, Kuhn, M, Khristov, V, Heebner, M, Wilding, H, Clegg, T, Bhanja, D, Wade, Q, Liermann, LJ, Wang, D, Smith, N, Remite-Berthet, G, Khunsriraksakul, C, Palsa, K, Slagle-Webb, B, Mansouri, SA, Zacharia, BE, Proctor, EA & Connor, J 2025, 'Analysis of transition metal content in glioblastoma reveals association between iron and survival', Translational Oncology, vol. 55, 102376. https://doi.org/10.1016/j.tranon.2025.102376
Sarfraz, Z, Jayram, D, Ozair, A, Hodgson, L, Bellur, S, Maharaj, A, Mansouri, A & Ahluwalia, MS 2025, 'Association of Health Disparities with Glioblastoma Treatment and Outcomes: Insights from a 15-Year National Cohort (2005–2020) †', Brain Sciences, vol. 15, no. 6, 556. https://doi.org/10.3390/brainsci15060556
Mansouri, A, Ozair, A, Bhanja, D, Wilding, H, Mashiach, E, Haque, W, Mikolajewicz, N, de Macedo Filho, L, Mahase, SS, Machtay, M, Metellus, P, Dhermain, F, Sheehan, J, Kondziolka, D, Lunsford, LD, Niranjan, A, Minniti, G, Li, J, Kalkanis, SN, Wen, PY, Kotecha, R, McDermott, MW, Bettegowda, C, Woodworth, GF, Brown, PD, Sahgal, A & Ahluwalia, MS 2025, 'Author Correction: Stereotactic radiosurgery for patients with brain metastases: current principles, expanding indications and opportunities for multidisciplinary care (Nature Reviews Clinical Oncology, (2025), 22, 5, (327-347), 10.1038/s41571-025-01013-1)', Nature Reviews Clinical Oncology, vol. 22, no. 12, pp. 996. https://doi.org/10.1038/s41571-025-01083-1
Layng, SC, Betsock, A, Mansouri, A, Komiya, T, Miccio, JA, Mahase, SS & Knisely, JPS 2025, 'Brain metastases from lung cancer: recent advances and novel therapeutic opportunities', Discover Oncology, vol. 16, no. 1, 157. https://doi.org/10.1007/s12672-025-01873-0
Aastha, A, Wilding, H, Mikolajewicz, N, Khan, S, Ignatchenko, V, De Macedo Filho, LJM, Bhanja, D, Remite-Berthet, G, Heebner, M, Glantz, M, Mansouri, A & Kislinger, T 2025, 'Cerebrospinal fluid protein biomarkers are associated with response to multiagent intraventricular chemotherapy in patients with CNS lymphoma', Neuro-Oncology Advances, vol. 7, no. 1, vdaf046. https://doi.org/10.1093/noajnl/vdaf046
Landry, AP, Wang, JZ, Patil, V, Liu, J, Gui, C, Ellenbogen, Y, Ajisebutu, A, Yefet, L, Wei, Q, Singh, O, Sosa, J, Mansouri, S, Cohen-Gadol, AA, Tabatabai, G, Tatagiba, M, Behling, F, Barnholtz-Sloan, JS, Sloan, AE, Chotai, S, Chambless, LB, Mansouri, A, Makarenko, S, Yip, S, Ehret, F, Capper, D, Tsang, DS, Moliterno, J, Gunel, M, Wesseling, P, Sahm, F, Aldape, K, Gao, A, Zadeh, G & Nassiri, F 2025, 'Chromosome 1p Loss and 1q Gain for Grading of Meningioma', JAMA Oncology, vol. 11, no. 6, pp. 644-649. https://doi.org/10.1001/jamaoncol.2025.0329
Aastha, A, De Macedo Filho, LJM, Woolman, M, Ignatchenko, V, Keszei, A, Remite-Berthet, G, Mansouri, A & Kislinger, T 2025, 'Comparative evaluation of analytical methods for CSF proteomics', Clinical Proteomics, vol. 22, no. 1, 46. https://doi.org/10.1186/s12014-025-09568-y
Pearlman, AH, Wang, Y, Kalluri, A, Parker, M, Cohen, JD, Dudley, J, Rincon-Torroella, J, Xia, Y, Gensler, R, Horowitz, MA, Theodore, JN, Dobbyn, L, Popoli, M, Ptak, J, Silliman, N, Judge, K, Calabresi, PA, Groves, M, Jackson, CM, Jackson, EM, Jallo, GI, Lim, M, Luciano, M, Mukherjee, D, Naidoo, J, Rozati, S, Sterling, CH, Weingart, J, Koschmann, C, Mansouri, A, Glantz, M, Kamson, D, Schreck, KC, Pardo, CA, Holdhoff, M, Konig, MF, Paul, S, Kinzler, KW, Papadopoulos, N, Vogelstein, B, Douville, C & Bettegowda, C 2025, 'Detection of Human Brain Cancers using Genomic and Immune Cell Characterization of Cerebrospinal Fluid through CSF-BAM', Cancer Discovery, vol. 15, no. 10, pp. 2002-2018. https://doi.org/10.1158/2159-8290.cd-24-1788
The International Consortium on Meningiomas (ICOM) 2025, 'Development and validation of a molecular classifier of meningiomas', Neuro-oncology, vol. 27, no. 5, pp. 1258-1269. https://doi.org/10.1093/neuonc/noae242
Tuohy, K, Mansouri, A, Tulchinsky, M, Ali, A, Le Rhun, E, Weller, M & Glantz, M 2025, 'Intra-Ommaya reservoir administration technique affects cerebrospinal fluid drug distribution in patients with leptomeningeal metastases', Neuro-Oncology Practice, vol. 12, no. 5, pp. 884-891. https://doi.org/10.1093/nop/npaf044
Tuohy, K, Dowd, R, Ali, A, Badani, A, Sichinga, K, Zacharia, BE, Mansouri, A, Aregawi, D & Glantz, M 2025, 'Medical Therapy Alone for Ommaya Reservoir-Associated Bacterial Meningitis: When It Works and When It Fails', Neurosurgery, vol. 97, no. 2, pp. 380-386. https://doi.org/10.1227/neu.0000000000003310
Bagley, SJ, Beaubier, N, Balaj, L, Bettegowda, C, Carpenter, E, Carter, BS, Corner, A, Dittamore, R, Grossman, RL, Hickman, RA, Kuhn, P, LeBlang, S, Lichtenberg, T, Mansouri, A, Miller, A, Ngo, T, Rood, BR, Till, J, Xu, L & Leiman, LC 2025, 'Minimum Technical Preanalytical, Patient, and Clinical Context Data Elements for Cerebrospinal Fluid Liquid Biopsy: Recommendations for Public Database Submissions', JCO Precision Oncology, vol. 9, e2400921. https://doi.org/10.1200/PO-24-00921
Fallahi, MS, Maroufi, SF, Parmis Maroufi, S, Khorasanizadeh, MH, de Macêdo Filho, LJM, Margetis, K, Guha, D, Tatsui, CE & Mansouri, A 2025, 'Percutaneous cryoablation in the management of spinal metastases: a comprehensive systematic review and meta-analysis', Journal of neuro-oncology, vol. 174, no. 2, pp. 303-314. https://doi.org/10.1007/s11060-025-05064-3
Trifoi, M, Tuohy, K, Sichinga, K, Levit, M, Zacharia, BE, Mansouri, A, Aregawi, D & Glantz, M 2026, 'Prevention of Ommaya Reservoir–Associated Bacterial Meningitis With Prophylactic Intraventricular Vancomycin', Neurosurgery, vol. 98, no. 3, pp. 643-650. https://doi.org/10.1227/neu.0000000000003647
PROTEST investigators 2025, 'Prophylaxis for venous thromboembolism in traumatic brain injury: protocol for a randomised controlled trial', BMJ open, vol. 15, no. 12, e114158. https://doi.org/10.1136/bmjopen-2025-114158
Muthiah, N, Reecher, HM, Maroufi, SF, Mansouri, A, Harford, E & Abel, TJ 2025, 'Seizure outcomes and complications associated with stereoelectroencephalography versus subdural electrodes for invasive monitoring in epilepsy surgery: a meta-analysis', Frontiers in Neurology, vol. 16, 1619288. https://doi.org/10.3389/fneur.2025.1619288
Mansouri, A, Ozair, A, Bhanja, D, Wilding, H, Mashiach, E, Haque, W, Mikolajewicz, N, de Macedo Filho, L, Mahase, SS, Machtay, M, Metellus, P, Dhermain, F, Sheehan, J, Kondziolka, D, Lunsford, LD, Niranjan, A, Minniti, G, Li, J, Kalkanis, SN, Wen, PY, Kotecha, R, McDermott, MW, Bettegowda, C, Woodworth, GF, Brown, PD, Sahgal, A & Ahluwalia, MS 2025, 'Stereotactic radiosurgery for patients with brain metastases: current principles, expanding indications and opportunities for multidisciplinary care', Nature Reviews Clinical Oncology, vol. 22, no. 5, 101402, pp. 327-347. https://doi.org/10.1038/s41571-025-01013-1
The International Consortium on Meningiomas (ICOM) 2025, 'Validation and next-generation update of a DNA methylation–based recurrence predictor for meningioma: A multicenter prospective study', Neuro-oncology, vol. 27, no. 4, pp. 1004-1016. https://doi.org/10.1093/neuonc/noae236
2024
Shenoy, G, Slagle-Webb, B, Khunsriraksakul, C, Pandya Shesh, B, Luo, J, Khristov, V, Smith, N, Mansouri, A, Zacharia, BE, Holder, S, Lathia, JD, Barnholtz-Sloan, JS & Connor, JR 2024, 'Analysis of anemia and iron supplementation among glioblastoma patients reveals sex-biased association between anemia and survival', Scientific reports, vol. 14, no. 1, 2389. https://doi.org/10.1038/s41598-024-52492-8
Mansouri, A, Nassiri, F, Scales, D & Pirouzmand, F 2024, 'Anticoagulation Therapy Timing in patients with Atrial Fibrillation after Acute and Chronic Subdural Haematoma (ATTAACH): A pilot randomised controlled trial', BMJ open, vol. 14, no. 10, e090224. https://doi.org/10.1136/bmjopen-2024-090224
Sabahi, M, Fathi Jouzdani, A, Sadeghian, Z, Dabbagh Ohadi, MA, Sultan, H, Salehipour, A, Maniakhina, L, Rezaei, N, Adada, B, Mansouri, A & Borghei-Razavi, H 2025, 'CAR-engineered NK cells versus CAR T cells in treatment of glioblastoma; strength and flaws', Journal of neuro-oncology, vol. 171, no. 3, pp. 495-530. https://doi.org/10.1007/s11060-024-04876-z
Hect, JL, Harford, E, Maroufi, SF, Klem, ML, Mansouri, A & Abel, TJ 2024, 'Clinical outcomes of MR-guided laser interstitial thermal therapy corpus callosum ablation in drug-resistant epilepsy: a systematic review and meta-analysis', Journal of Neurosurgery: Pediatrics, vol. 33, no. 1, pp. 12-21. https://doi.org/10.3171/2023.9.PEDS23326
de Macêdo Filho, LJM, Mansouri, A, Otamendi-Lopez, A, Sarigul, B, Diógenes, AVG, Carate, CK, Torquato, GCP, de Andrade, PP & Rizk, E 2024, 'Congenital Pediatric Hydrocephalus in the Brazilian Public Health System: The Reality of a Middle-Income Country in the Past 13 Years', World Neurosurgery, vol. 181, pp. e801-e808. https://doi.org/10.1016/j.wneu.2023.10.137
Mansouri, A, Wilding, HE, Mikolajewicz, N, Bhanja, D, Moeckel, C, Ozair, A, Hamidi, N, Tankam, C, Stoltzfus, M, Baroz, AR, Stahl, C, Trifoi, M, Dudek, C & Ahluwalia, MS 2024, 'Development of clinically accessible nomograms to predict risk of brain metastases at baseline and follow-up in patients with non-small cell lung cancer', Journal of Clinical Oncology, vol. 42, no. 16, 2035. https://doi.org/10.1200/JCO.2024.42.16_suppl.2035
Mansouri, A, Bhanja, D, Wilding, HE, Mikolajewicz, N, Ozair, A & Ahluwalia, MS 2024, 'Dual-agent immunotherapy for prevention of melanoma brain metastases: A real-world analysis of 8686 patients.', Journal of Clinical Oncology, vol. 42, pp. 2022. https://doi.org/10.1200/JCO.2024.42.16_suppl.2022
Ledford, A, Rodriguez, A, Lipinski, L, Abad, A, Fenstermaker, R, Edenfield, J, Kanos, C, Redjal, N, Mansouri, A, Zacharia, B, Butowski, N, Liu, J, Han, SJ, Ziu, M, Cohen, AL, Fabiano, AJ, Miles, K, Rayner, M, Thompson, J, Tollison, K, Azimzadeh, P, Holmes, L, Gevaert, M & DesRochers, TM 2024, 'Functional prediction of response to therapy prior to therapeutic intervention is associated with improved survival in patients with high-grade glioma', Scientific reports, vol. 14, no. 1, 19474. https://doi.org/10.1038/s41598-024-68801-0
Ghorbani, A, Chatanaka, MK, Avery, LM, Wang, M, Brown, J, Cohen, R, Gorham, T, Misaghian, S, Padmanabhan, N, Romero, D, Stengelin, M, Mathew, A, Sigal, G, Wohlstadter, J, Horbinski, C, McCortney, K, Xu, W, Zadeh, G, Mansouri, A, Yousef, GM, Diamandis, EP & Prassas, I 2024, 'Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers', Clinical Proteomics, vol. 21, no. 1, 41. https://doi.org/10.1186/s12014-024-09492-7
Badani, A, Ozair, A, Khasraw, M, Woodworth, GF, Tiwari, P, Ahluwalia, MS & Mansouri, A 2025, 'Immune checkpoint inhibitors for glioblastoma: emerging science, clinical advances, and future directions', Journal of neuro-oncology, vol. 171, no. 3, pp. 531-547. https://doi.org/10.1007/s11060-024-04881-2
Ozair, A, Wilding, H, Bhanja, D, Mikolajewicz, N, Glantz, M, Grossman, SA, Sahgal, A, Le Rhun, E, Weller, M, Weiss, T, Batchelor, TT, Wen, PY, Haas-Kogan, DA, Khasraw, M, Rudà, R, Soffietti, R, Vollmuth, P, Subbiah, V, Bettegowda, C, Pham, LC, Woodworth, GF, Ahluwalia, MS & Mansouri, A 2025, 'Leptomeningeal metastatic disease: new frontiers and future directions', Nature Reviews Clinical Oncology, vol. 22, no. 2, 82, pp. 134-154. https://doi.org/10.1038/s41571-024-00970-3
Mikolajewicz, N, Yee, PP, Bhanja, D, Trifoi, M, Miller, AM, Metellus, P, Bagley, SJ, Balaj, L, De MacEdo Filho, LJM, Zacharia, BE, Aregawi, D, Glantz, M, Weller, M, Ahluwalia, MS, Kislinger, T & Mansouri, SA 2024, 'Systematic Review of Cerebrospinal Fluid Biomarker Discovery in Neuro-Oncology: A Roadmap to Standardization and Clinical Application', Journal of Clinical Oncology, vol. 42, no. 16, pp. 1961-1974. https://doi.org/10.1200/JCO.23.01621
Kermanshahi, N, Hamidi, N, Weisberg, J, Beg, U, Dabrowski, M, Padmanaban, V, Betz, J & Mansouri, A 2024, 'The Prevalence of Seizures in Brain Metastasis Patients on Anticonvulsant Prophylaxis: A Systematic Review and Meta-Analysis', World Neurosurgery, vol. 183, pp. e613-e624. https://doi.org/10.1016/j.wneu.2023.12.154
Metellus, P, Camilla, C, Bialecki, E, Beaufils, N, Vellutini, C, Pellegrino, E, Tomasini, P, Ahluwalia, MS, Mansouri, A, Nanni, I & Ouafik, LH 2024, 'The landscape of cancer-associated transcript fusions in adult brain tumors: a longitudinal assessment in 140 patients with cerebral gliomas and brain metastases', Frontiers in Oncology, vol. 14, 1382394. https://doi.org/10.3389/fonc.2024.1382394
2023
Tavallaii, A & Mansouri, A 2023, Awake Craniotomy for Tumor Surgery <Awake Craniotomy, Tumor, Mapping> in The Principles of Successful Awake Craniotomy: Perioperative Tips and Tricks. Springer Nature, pp. 9-27. https://doi.org/10.1007/978-981-99-2985-6_2
Zuccato, JA, Patil, V, Mansouri, S, Voisin, M, Chakravarthy, A, Yi Shen, S, Nassiri, F, Mikolajewicz, N, Trifoi, M, Skakodub, A, Zacharia, B, Glantz, M, De Carvalho, DD, Mansouri, A & Zadeh, G 2023, 'Cerebrospinal fluid methylome-based liquid biopsies for accurate malignant brain neoplasm classification', Neuro-oncology, vol. 25, no. 8, pp. 1452-1460. https://doi.org/10.1093/neuonc/noac264
Tuohy, K, Ba, DM, Bhanja, D, Leslie, D, Liu, G & Mansouri, A 2023, 'Early costs and complications of first-line low-grade glioma treatment using a large national database: Limitations and future perspectives', Frontiers in Surgery, vol. 10, 1001741. https://doi.org/10.3389/fsurg.2023.1001741
Warsi, NM, Mohammad, AH, Zhang, F, Wong, SM, Yan, H, Mansouri, A & Ibrahim, GM 2023, 'Electrocorticography-Guided Resection Enhances Postoperative Seizure Freedom in Low-Grade Tumor-Associated Epilepsy: A Systematic Review and Meta-Analysis', Neurosurgery, vol. 92, no. 1, pp. 18-26. https://doi.org/10.1227/neu.0000000000002182
Pascual, JSG & Mansouri, A 2023, Intraoperative Nuances of Awake Craniotomy <Surgical Nuances, Awake Craniotomy> in The Principles of Successful Awake Craniotomy: Perioperative Tips and Tricks. Springer Nature, pp. 87-95. https://doi.org/10.1007/978-981-99-2985-6_7
Sabahi, M, Salehipour, A, Bazl, MSY, Rezaei, N, Mansouri, A & Borghei-Razavi, H 2023, 'Local immunotherapy of glioblastoma: A comprehensive review of the concept', Journal of Neuroimmunology, vol. 381, 578146. https://doi.org/10.1016/j.jneuroim.2023.578146
Bhanja, D, Wilding, H, Baroz, A, Trifoi, M, Shenoy, G, Slagle-Webb, B, Hayes, D, Soudagar, Y, Connor, J & Mansouri, A 2023, 'Photodynamic Therapy for Glioblastoma: Illuminating the Path toward Clinical Applicability', Cancers, vol. 15, no. 13, 3427. https://doi.org/10.3390/cancers15133427
Mofatteh, M, Mashayekhi, MS, Arfaie, S, Chen, Y, Malhotra, AK, Alvi, MA, Sader, N, Antonick, V, Fatehi Hassanabad, M, Mansouri, A, Das, S, Liao, X, McIntyre, RS, Del Maestro, R, Turecki, G, Cohen-Gadol, AA, Zadeh, G & Ashkan, K 2023, 'Suicidal ideation and attempts in brain tumor patients and survivors: A systematic review', Neuro-Oncology Advances, vol. 5, no. 1, vdad058. https://doi.org/10.1093/noajnl/vdad058
Mansouri, A, Ibrahim, S, Bello, L, Martino, J & Velasquez, C 2023, 'The current state of the art of primary motor mapping for tumor resection: A focused survey', Clinical Neurology and Neurosurgery, vol. 229, 107685. https://doi.org/10.1016/j.clineuro.2023.107685
2022
Mansouri, A, Lai, C, Scales, D & Pirouzmand, F 2022, 'A phase II pilot randomized controlled trial to assess the feasibility of the “supra-marginal” surgical resection of malignant glioma (G-SUMIT: Glioma supra marginal incision trial) study protocol', Pilot and Feasibility Studies, vol. 8, no. 1, 138. https://doi.org/10.1186/s40814-022-01104-1
Bhanja, D, Ba, D, Tuohy, K, Wilding, H, Trifoi, M, Padmanaban, V, Liu, G, Sughrue, M, Zacharia, B, Leslie, D & Mansouri, A 2022, 'Association of Low-Grade Glioma Diagnosis and Management Approach with Mental Health Disorders: A MarketScan Analysis 2005–2014', Cancers, vol. 14, no. 6, 1376. https://doi.org/10.3390/cancers14061376
Qazi, MA, Salim, SK, Brown, KR, Mikolajewicz, N, Savage, N, Han, H, Subapanditha, MK, Bakhshinyan, D, Nixon, A, Vora, P, Desmond, K, Chokshi, C, Singh, M, Khoo, A, Macklin, A, Khan, S, Tatari, N, Winegarden, N, Richards, L, Pugh, T, Bock, N, Mansouri, A, Venugopal, C, Kislinger, T, Goyal, S, Moffat, J & Singh, SK 2022, 'Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma', Cell Reports, vol. 40, no. 13, 111420. https://doi.org/10.1016/j.celrep.2022.111420
Singh, K, Batich, KA, Wen, PY, Tan, AC, Bagley, SJ, Lim, M, Platten, M, Colman, H, Ashley, DM, Chang, SM, Rahman, R, Galanis, E, Mansouri, A, Puduvalli, VK, Reardon, DA, Sahebjam, S, Sampson, JH, Simes, J, Berry, DA, Zadeh, G, Cloughesy, TF, Mehta, MP, Piantadosi, S, Weller, M, Heimberger, AB & Khasraw, M 2022, 'Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma', Clinical Cancer Research, vol. 28, no. 4, pp. 585-593. https://doi.org/10.1158/1078-0432.CCR-21-2681
EORTC BTG, ICOM, EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS, TBTC, International Brain Tumour Alliance, Brainstrust, and Brain Tumour Foundation of Canada 2022, 'Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings', BMJ open, vol. 12, no. 5, e057384. https://doi.org/10.1136/bmjopen-2021-057384
Hamidi, N, Karmur, B, Sperrazza, S, Alexieva, J, Salmi, L, Zacharia, BE, Nduom, EK, Cohen-Gadol, AA, Rutka, JT & Mansouri, A 2022, 'Guidelines for optimal utilization of social media for brain tumor stakeholders', Journal of neurosurgery, vol. 136, no. 2, pp. 335-342. https://doi.org/10.3171/2020.11.JNS203226
Loh, A, Germann, J, Qazi, S, Husain, R, Boutet, A, Lozano, AM & Mansouri, A 2022, 'Lesion network mapping of ectopic craniopharyngioma identifies potential cause of psychosis: a case report', Acta Neurochirurgica, vol. 164, no. 12, pp. 3285-3289. https://doi.org/10.1007/s00701-022-05355-y
Mikolajewicz, N, Khan, S, Trifoi, M, Skakdoub, A, Ignatchenko, V, Mansouri, S, Zuccatto, J, Zacharia, BE, Glantz, M, Zadeh, G, Moffat, J, Kislinger, T & Mansouri, A 2022, 'Leveraging the CSF proteome toward minimally-invasive diagnostics surveillance of brain malignancies', Neuro-Oncology Advances, vol. 4, no. 1, vdac161. https://doi.org/10.1093/noajnl/vdac161
Lubelski, D, Pennington, Z, Ochuba, A, Azad, TD, Mansouri, A, Blakeley, J & Belzberg, AJ 2022, 'Natural History of Brachial Plexus, Peripheral Nerve, and Spinal Schwannomas', Neurosurgery, vol. 91, no. 6, pp. 883-891. https://doi.org/10.1227/neu.0000000000002118
Bhanja, D, Neighbors, J, Connor, J, Zadeh, G & Mansouri, A 2022, 'Neuropharmacological Study of Posaconazole for Glioblastoma: A Phase 0 Clinical Trial Protocol', Neurosurgery, vol. 91, no. 4, pp. 658-665. https://doi.org/10.1227/neu.0000000000002071
Germann, J, Zadeh, G, Mansouri, A, Kucharczyk, W, Lozano, AM & Boutet, A 2022, 'Untapped Neuroimaging Tools for Neuro-Oncology: Connectomics and Spatial Transcriptomics', Cancers, vol. 14, no. 3, 464. https://doi.org/10.3390/cancers14030464