Researcher Profile

Researcher Profile

John Flanagan, PhD

John Flanagan, PhD

Professor, Department of Biochemistry and Molecular Biology
Scientific Program:Next-Generation Therapies
jmf27@psu.edu

Research Interests

  • Proteins
  • Escherichia coli
  • Peptides
  • X-Rays
  • Adenosine Triphosphatases
  • Mutation
  • DNA
  • Adenosine Triphosphate
  • Amino Acids
  • Nucleic Acids
  • Transfer RNA
  • Occludin

Recent Publications

2021

Ye, Y, Tyndall, ER, Bui, V, Tang, Z, Shen, Y, Jiang, X, Flanagan, JM, Wang, HG & Tian, F 2021, 'An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy', Nature communications, vol. 12, no. 1, 374. https://doi.org/10.1038/s41467-020-20607-0

2020

Bewley, MC, Gautam, L, Jagadeeshaprasad, MG, Channe Gowda, D & Flanagan, JM 2020, 'Molecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding', Journal of Biological Chemistry, vol. 295, no. 52, pp. 18589-18603. https://doi.org/10.1074/jbc.RA120.014676

2017

Bewley, MC, Reinhart, L, Stake, MS, Nadaraia-Hoke, S, Parent, LJ & Flanagan, JM 2017, 'A non-cleavable hexahistidine affinity tag at the carboxyl-terminus of the HIV-1 Pr55Gag polyprotein alters nucleic acid binding properties', Protein Expression and Purification, vol. 130, pp. 137-145. https://doi.org/10.1016/j.pep.2016.10.001
Clark, DN, Flanagan, JM & Hu, J 2017, 'Mapping of functional subdomains in the terminal protein domain of hepatitis B virus polymerase', Journal of virology, vol. 91, no. 3, e01785-16. https://doi.org/10.1128/JVI.01785-16

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)