Researcher Profile

Researcher Profile

David Goldenberg, MD

David Goldenberg, MD

Steven and Sharon Baron Professor and Chair, Department of Otolaryngology - Head and Neck Surgery
Professor, Department of Surgery
Professor, Department of Medicine
Scientific Program:Cancer Control
Disease Teams:
Head and Neck Cancer
dug5@psu.edu

Research Interests

Dr. David Goldenberg's basic science research focuses on thyroid cancer genomics as well as radiation-included and familial thyroid cancer. His clinical research focus is on outcomes and etiology of the rise in incidence of thyroid cancer. 

  • Neoplasms
  • Neck
  • Thyroid Neoplasms
  • Therapeutics
  • Head and Neck Neoplasms
  • Head
  • Thyroid Gland
  • Tracheotomy
  • Guidelines
  • Incidence
  • Anatomy
  • Papillary Thyroid Cancer

Clinical Trials

NRG-HN005 - A Randomized Phase II/III Trial of De-intensified Radiation Therapy for Patients with Early-Stage, P16-Positive, Non-Smoking Associated Oropharyngeal Cancer
Head and Neck Cells: Tissue Repository
Understanding Factors that Impact Thyroid Cancer Incidence in Women

Recent Publications

2020

Saadi, RA, Bann, DV, Patel, VA, Goldenberg, D, May, J & Isildak, H 2020, 'A Commentary on Safety Precautions for Otologic Surgery during the COVID-19 Pandemic', Otolaryngology - Head and Neck Surgery (United States), vol. 162, no. 6, pp. 797-799. https://doi.org/10.1177/0194599820919741
Hwang, G, Goldenberg, D, Warrick, J & Slonimsky, G 2020, 'A Hyalinizing Clear Cell Carcinoma of the Base of Tongue', Ear, Nose and Throat Journal, vol. 99, no. 4, pp. 237-238. https://doi.org/10.1177/0145561319840513
Bann, DV, Patel, VA, Saadi, R, Goyal, N, Gniady, JP, McGinn, JD, Goldenberg, D, Isildak, H, May, J & Wilson, MN 2020, 'Best Practice Recommendations for Pediatric Otolaryngology during the COVID-19 Pandemic', Otolaryngology - Head and Neck Surgery (United States), vol. 162, no. 6, pp. 783-794. https://doi.org/10.1177/0194599820921393
Sataloff, RT, Chandra, R, Fisher, EW, Goldenberg, D, Hanna, EY, Johnson, J, Kennedy, DW, Kraus, DH, Krouse, JH, Link, M, Lustig, LR, O'Malley, BW, Piccirillo, JF, Ruben, R, Schwartz, S, Selesnick, SH, Sindwani, R, Smith, RJ, Stewart, MG, Tysome, J, Weber, PC & Welling, DB 2020, 'Consortium of Otolaryngology Journal Editors: Collegiality and contributions', International Journal of Pediatric Otorhinolaryngology, vol. 134, 109959. https://doi.org/10.1016/j.ijporl.2020.109959
Sataloff, RT, Chandra, R, Fisher, EW, Goldenberg, D, Hanna, EY, Johnson, J, Kennedy, DW, Kraus, DH, Krouse, JH, Link, M, Lustig, LR, O'Malley, BW, Piccirillo, JF, Ruben, R, Schwartz, S, Selesnick, SH, Sindwani, R, Smith, RJ, Stewart, MG, Tysome, J, Weber, PC & Welling, DB 2020, 'Consortium of Otolaryngology Journal Editors - Collegiality and Contributions', JAMA Otolaryngology - Head and Neck Surgery, vol. 146, no. 6, pp. 521-522. https://doi.org/10.1001/jamaoto.2020.0525
Sataloff, RT, Chandra, R, Fisher, EW, Goldenberg, D, Hanna, EY, Johnson, J, Kennedy, DW, Kraus, DH, Krouse, JH, Link, M, Lustig, LR, O'Malley, JBW, Piccirillo, JF, Ruben, R, Schwartz, S, Selesnick, SH, Sindwani, R, Smith, RJ, Stewart, MG, Tysome, J, Weber, PC & Welling, DB 2020, 'Consortium of otolaryngology journal editors: Collegiality and contributions', Operative Techniques in Otolaryngology - Head and Neck Surgery, vol. 31, no. 2, pp. 71-73. https://doi.org/10.1016/j.otot.2020.02.001
Bann, DV, Patel, VA, Saadi, R, Gniady, JP, Goyal, N, McGinn, JD & Goldenberg, D 2020, 'Impact of coronavirus (COVID-19) on otolaryngologic surgery: Brief commentary', Head and Neck, vol. 42, no. 6, pp. 1227-1234. https://doi.org/10.1002/hed.26162
LaBarge, B, Walter, V, Bann, DV & Goldenberg, D 2020, 'In-depth analysis of thyroid cancer mortality', Head and Neck. https://doi.org/10.1002/hed.26577
Roman, BR, Lohia, S, Mitra, N, Wang, MB, Pou, AM, Holsinger, FC, Myssiorek, D, Goldenberg, D, Asch, DA & Shea, JA 2020, 'Perceived value drives use of routine asymptomatic surveillance PET/CT by physicians who treat head and neck cancer', Head and Neck, vol. 42, no. 5, pp. 974-987. https://doi.org/10.1002/hed.26071
Slonimsky, G, Hawng, G, Goldenberg, D, Gagnon, E & Slonimsky, E 2020, 'Terminology, Definitions, and Classification in the Imaging of Laryngoceles', Current Problems in Diagnostic Radiology. https://doi.org/10.1067/j.cpradiol.2020.06.002
Keane, A & Goldenberg, D 2020, 'The difficult airway and thyroid surgery', Operative Techniques in Otolaryngology - Head and Neck Surgery, vol. 31, no. 2, pp. 138-143. https://doi.org/10.1016/j.otot.2020.04.010
Ruszkay, N, Goldenberg, D & Slonimsky, G 2020, 'Thyroid surgery in the elderly', Operative Techniques in Otolaryngology - Head and Neck Surgery, vol. 31, no. 3, pp. 206-210. https://doi.org/10.1016/j.otot.2020.07.005

2019

Zafereo, M, Yu, J, Angelos, P, Brumund, K, Chuang, HH, Goldenberg, D, Lango, M, Perrier, N, Randolph, G, Shindo, ML, Singer, M, Smith, R, Stack, BC, Steward, D, Terris, DJ, Vu, T, Yao, M & Tufano, RP 2019, 'American Head and Neck Society Endocrine Surgery Section update on parathyroid imaging for surgical candidates with primary hyperparathyroidism', Head and Neck, vol. 41, no. 7, pp. 2398-2409. https://doi.org/10.1002/hed.25781
Saadi, R, Brandt, A, Kim, Y, Cottrill, E, Saunders, B, Schaefer, E & Goldenberg, D 2020, 'Degree of technical difficulty of thyroidectomy for autoimmune thyroid disease', Head and Neck, vol. 42, no. 2, pp. 262-268. https://doi.org/10.1002/hed.25991
Bann, DV, Jin, Q, Sheldon, KE, Houser, KR, Nguyen, L, Warrick, JI, Baker, MJ, Broach, JR, Gerhard, GS & Goldenberg, D 2019, 'Genetic variants implicate dual oxidase-2 in familial and sporadic nonmedullary thyroid cancer', Cancer Research, vol. 79, no. 21, pp. 5490-5499. https://doi.org/10.1158/0008-5472.CAN-19-0721
Pool, C, Walter, V, Bann, D, Goldenberg, D, Broach, J, Hennessy, M, Cottrill, E, Washburn, E, Williams, N, Crist, H, Imamura, Y & Warrick, JI 2019, 'Molecular characterization of tumors meeting diagnostic criteria for the non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)', Virchows Archiv, vol. 474, no. 3, pp. 341-351. https://doi.org/10.1007/s00428-018-02512-6
Bailey, D & Goldenberg, D 2019, 'Surgical anatomy of the larynx', Operative Techniques in Otolaryngology - Head and Neck Surgery, vol. 30, no. 4, pp. 232-236. https://doi.org/10.1016/j.otot.2019.09.002
Goldenberg, D 2019, 'We cannot ignore the real component of the rise in thyroid cancer incidence', Cancer, vol. 125, no. 14, pp. 2362-2363. https://doi.org/10.1002/cncr.32123

2018

Slonimsky, G, Baker, A, Crist, H & Goldenberg, D 2018, 'A midline mediastinal parathyroid cyst', Ear, Nose and Throat Journal, vol. 97, no. 3, pp. 58-60. https://doi.org/10.1177/014556131809700305
Ferster, APOC, Slonimsky, G, Slonimsky, E, Crist, H & Goldenberg, D 2018, 'Burkitt lymphoma of the thyroid gland', Ear, Nose and Throat Journal, vol. 97, no. 7, pp. 196-197.
Saadi, R, LaRusso, S, Vijay, K & Goldenberg, D 2018, 'Elastography as a potential modality for screening cervical lymph nodes in patients with papillary thyroid cancer: A review of literature', Ear, Nose and Throat Journal, vol. 97, no. 1-2, pp. 31-39.
Labarge, B, Walter, V, Lengerich, EJ, Crist, H, Karamchandani, D, Williams, N, Goldenberg, D, Bann, DV & Warrick, JI 2018, 'Evidence of a positive association between malpractice climate and thyroid cancer incidence in the United States', PloS one, vol. 13, no. 7, e0199862. https://doi.org/10.1371/journal.pone.0199862
Goldenberg, D, Swegal, W, Dunklebarger, M & Pellitteri, PK 2018, 'Surgery for fibro-adherent inflammatory thyroid disease', Operative Techniques in Otolaryngology - Head and Neck Surgery, vol. 29, no. 1, pp. 2-9. https://doi.org/10.1016/j.otot.2017.12.002
Goldenberg, D, Ferris, RL, Shindo, ML, Shaha, A, Stack, B & Tufano, RP 2018, 'Thyroidectomy in patients who have undergone gastric bypass surgery', Head and Neck, vol. 40, no. 6, pp. 1237-1244. https://doi.org/10.1002/hed.25098
Cottrill, EE, Funk, EK, Goldenberg, D & Goyal, N 2019, 'Transoral Thyroidectomy Using A Flexible Robotic System: A Preclinical Cadaver Feasibility Study', Laryngoscope, vol. 129, no. 6, pp. 1482-1487. https://doi.org/10.1002/lary.27543
Persky, MJ, Issa, M, Bonfili, JR, Goyal, N, Goldenberg, D & Duvvuri, U 2018, 'Transoral surgery using the Flex Robotic System: Initial experience in the United States', Head and Neck, vol. 40, no. 11, pp. 2482-2486. https://doi.org/10.1002/hed.25375
Stahl, LE, Stewart, R, Carr, MM, Goldenberg, D & Schubart, JR 2018, 'Treatment preferences and decision-making in patients diagnosed with indeterminate thyroid nodules', Psycho-Oncology, vol. 27, no. 12, pp. 2862-2864. https://doi.org/10.1002/pon.4865
Saadi, R, Goldenberg, D & Goldenberg, D 2018, Using Technology in Global Otolaryngology. in L Mansur, B Riemer & D McClintock (eds), Otolaryngologic Clinics of North America. 3 edn, vol. 51, W.B. Saunders, pp. 555-561. https://doi.org/10.1016/j.otc.2018.01.004

2017

Yesensky, J, Agrawal, N, Bayan, S, Blair, E, Portugal, L, Chan, J, Goldenberg, D & Gooi, Z 2017, 'AHNS Series – Do you know your guidelines? Principles of treatment for glottic cancer: A review of the National Comprehensive Cancer Network guidelines', Head and Neck, vol. 39, no. 9, pp. 1729-1732. https://doi.org/10.1002/hed.24816
Gooi, Z, Richmon, J, Agrawal, N, Blair, E, Portugal, L, Vokes, E, Seiwert, T, de Souza, J, Saloura, V, Haraf, D, Goldenberg, D & Chan, J 2017, 'AHNS Series – Do you know your guidelines? Principles of treatment for nasopharyngeal cancer: A review of the National Comprehensive Cancer Network guidelines', Head and Neck, vol. 39, no. 2, pp. 201-205. https://doi.org/10.1002/hed.24635
Guo, T, Goldenberg, D & Fakhry, C 2017, 'AHNS series: Do you know your guidelines? Management of head and neck cancer in the era of human papillomavirus: Educating our patients on human papillomavirus', Head and Neck, vol. 39, no. 5, pp. 833-839. https://doi.org/10.1002/hed.24693
Goldenberg, D, Russo, M, Houser, K, Crist, H, Derr, JB, Walter, V, Warrick, JI, Sheldon, KE, Broach, J & Bann, DV 2017, 'Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident', Laryngoscope, vol. 127, pp. S1-S9. https://doi.org/10.1002/lary.26687
Ferster, APOC, Schubart, J, Kim, Y & Goldenberg, D 2017, 'Association between laryngeal cancer and asbestos exposure: A systematic review', JAMA Otolaryngology - Head and Neck Surgery, vol. 143, no. 4, pp. 409-416. https://doi.org/10.1001/jamaoto.2016.3421
Clark, CM, Payne, SJ, Warrick, JI & Goldenberg, D 2017, 'Atypical parathyroid adenoma with diffuse fibrosis', Ear, Nose and Throat Journal, vol. 96, no. 2, pp. 57-58. https://doi.org/10.1177/014556131709600206
Shah-Becker, S, Pennock, M, Sinoway, L, Goldenberg, D & Goyal, N 2017, 'Baroreceptor reflex failure: Review of the literature and the potential impact on patients with head and neck cancer', Head and Neck, vol. 39, no. 10, pp. 2135-2141. https://doi.org/10.1002/hed.24857
Estes, SJ, Goldenberg, D, Winder, JS, Juza, RM & Lyn-Sue, JR 2017, 'Best practices for robotic surgery programs', Journal of the Society of Laparoendoscopic Surgeons, vol. 21, no. 2, e2016.00102. https://doi.org/10.4293/JSLS.2016.00102
Funk, E, Goldenberg, D & Goyal, N 2017, 'Demonstration of transoral robotic supraglottic laryngectomy and total laryngectomy in cadaveric specimens using the Medrobotics Flex System', Head and Neck, vol. 39, no. 6, pp. 1218-1225. https://doi.org/10.1002/hed.24746
Shah-Becker, S, Derr, J, Oberman, BS, Baker, A, Saunders, B, Carr, MM & Goldenberg, D 2018, 'Early neurocognitive improvements following parathyroidectomy for primary hyperparathyroidism', Laryngoscope, vol. 128, no. 3, pp. 775-780. https://doi.org/10.1002/lary.26617
Shokri, T & Goldenberg, D 2017, 'Emergency operative airway techniques', Operative Techniques in Otolaryngology - Head and Neck Surgery, vol. 28, no. 4, pp. 252-257. https://doi.org/10.1016/j.otot.2017.08.010
Patel, VA, Zacharia, TT, Goldenberg, D & McGinn, JD 2017, 'End-organ radiographic manifestations of cranial neuropathies: A concise review', Clinical Imaging, vol. 44, pp. 5-11. https://doi.org/10.1016/j.clinimag.2017.03.014
Khaku, A, Patel, V, Zacharia, TT, Goldenberg, D & McGinn, J 2017, 'Guidelines for radiographic imaging of cranial neuropathies', Ear, Nose and Throat Journal, vol. 96, no. 10-11, E23. https://doi.org/10.1177/0145561317096010-1106
Baker, A, Cottrill, EE, Munizza, O, McGillen, K, McKinnon, T & Goldenberg, D 2017, 'Intrathyroidal carotid artery and nonrecurring right recurrent laryngeal nerve: A case report', Head and Neck, vol. 39, no. 12, pp. E123-E126. https://doi.org/10.1002/hed.24970
Liu, J, Goldenberg, D, Almokadem, S, Crist, H & Mackley, HB 2017, 'Long-term recurrence-free survival after an unplanned reduction in radiotherapy for HPV-positive oropharyngeal SCC: Two cases and a review of the literature', Ear, Nose and Throat Journal, vol. 96, no. 7, E23. https://doi.org/10.1177/014556131709600705
Goyal, N, Pakdaman, M, Kamani, D, Caragacianu, D, Goldenberg, D & Randolph, GW 2017, 'Mapping the distribution of nodal metastases in papillary thyroid carcinoma: Where exactly are the nodes?', Laryngoscope, vol. 127, no. 8, pp. 1959-1964. https://doi.org/10.1002/lary.26495
Gerhard, GS, Bann, DV, Broach, J & Goldenberg, D 2017, 'Pitfalls of exome sequencing: A case study of the attribution of HABP2 rs7080536 in familial non-medullary thyroid cancer', npj Genomic Medicine, vol. 2, no. 1, 8. https://doi.org/10.1038/s41525-017-0011-x
Goyal, N, Funk, E & Goldenberg, D 2018, 'Reply to Letter to the Editor regarding “Robotic or non-robotic transoral laryngectomy”', Head and Neck, vol. 40, no. 1. https://doi.org/10.1002/hed.25010

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)