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Seth Hardy, MD, MBA

Seth Hardy, MD, MBA

Assistant Professor, Department of Radiology
Scientific Program:Cancer Control

Research Interests

Dr. Seth Hardy's research interests are at the intersection of hematology/oncology, imaging, patient-centered care and value creation. As a leukemia survivor himself, currently enrolled in a Phase II trial at the National Institutes of Health, he has a patient's perspective on the delivery of hematology/oncology care, clinical trials and potential shortcomings in today's medical environment.

He is currently developing a pilot clinical trial in patients on checkpoint inhibitors to develop imaging biomarkers that may provide efficacy feedback inside the typical CT/MR iRECIST 16-week cycle. He also co-leads an ad hoc sono-oncology workgroup across campuses at Penn State.

Dr. Hardy also publishes on economic and strategic topics within imaging and medicine.

  • Radiology
  • Hypoxia
  • Coronavirus
  • Psychological Burnout
  • Breast
  • Gases
  • Human Activities
  • Lymphadenopathy
  • Psychological Practice
  • Mammography
  • Sleep Apnea Syndromes
  • Hypercapnia

Recent Publications


Moore, MM, Gagnon, E, Arbaiza, A, Bruno, MA, Hardy, S, Mosher, TJ & Sarwani, NI 2024, 'Enterprise Radiology Dashboard Development Facilitating Academic and Community Practice Integration', Journal of the American College of Radiology, vol. 21, no. 3, pp. 523-527.


Berland, LL & Hardy, SM 2023, 'Fighting Obsolescence: Professional Assessment in the Era of ChatGPT', Applied Radiology, vol. 52, no. 3, pp. 20-23.


Petscavage-Thomas, JM, Hardy, S & Chetlen, A 2022, 'Mitigation Tactics Discovered During COVID-19 with Long-Term Report Turnaround Time and Burnout Reduction Benefits', Academic Radiology, vol. 29, no. 12, pp. 1786-1791.
Brown, SD, Hardy, SM & Bruno, MA 2022, 'Rationing and Disparities in Health Care: Implications for Radiology Clinical Practice Guidelines', Journal of the American College of Radiology, vol. 19, no. 1, pp. 84-89.
Hardy, SM 2022, 'Tort Reform: Be Careful What You Wish for, You Just Might Get It', Journal of the American College of Radiology, vol. 19, no. 7, pp. 821-822.


Hardy, SM, McGillen, KL & Hausman, BL 2021, 'Dr Mom's Added Burden', Journal of the American College of Radiology, vol. 18, no. 1, pp. 103-107.
Hardy, SM 2021, 'Value chain: Where radiologists should put their focus in threats against income', Applied Radiology, vol. 50, no. 4, pp. 32-34.


Bruno, MA, Hardy, SM & Donnelly, EF 2020, 'Defining "voluntary"', American Journal of Roentgenology, vol. 215, no. 2, pp. W21.
Hardy, SM 2020, 'Diagnostic imaging at rural hospitals', Health Affairs, vol. 39, no. 5, pp. 905.
Hardy, SM, Lexa, FJ & Bruno, MA 2020, 'Potential Implications of Current Corporate Strategy for the US Radiology Industry', Journal of the American College of Radiology, vol. 17, no. 3, pp. 361-364.