Yi Qiu, PhD - Penn State Cancer Institute
Researcher Profile
Yi Qiu, PhD
Associate Professor, Department of Cell and Biological Systems
Scientific Program:Mechanisms of Carcinogenesis
Recent Publications
2025
Hamamoto, K, Zhu, G, Lai, Q, Lesperance, J, Luo, H, Li, Y, Nigam, N, Sharma, A, Yang, FC, Claxton, D, Qiu, Y, Aplan, PD, Xu, M & Huang, S 2025, 'HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98-rearranged leukemia', Journal of Clinical Investigation, vol. 135, no. 7, e184743. https://doi.org/10.1172/JCI184743
Matur, M, Uzun, Y, Shi, X, Hamamoto, K, Qiu, Y & Huang, S 2025, 'Noncoding RNA, ncRNA-a3, Epigenetically Regulates TAL1 Transcriptional Program During Erythropoiesis', Molecular and cellular biology, vol. 45, no. 4, pp. 169-184. https://doi.org/10.1080/10985549.2025.2482079
2024
Zhou, H, Qin, D, Xie, C, Zhou, J, Jia, S, Zhou, Z, Qiu, Y, Xu, B & Zha, J 2024, 'Combinations of HDAC Inhibitor and PPAR Agonist Induce Ferroptosis of Leukemic Stem Cell-like Cells in Acute Myeloid Leukemia', Clinical Cancer Research, vol. 30, no. 23, pp. 5430-5444. https://doi.org/10.1158/1078-0432.CCR-24-0796
2023
Lai, Q, Hamamoto, K, Luo, H, Zaroogian, Z, Zhou, C, Lesperance, J, Zha, J, Qiu, Y, Guryanova, OA, Huang, S & Xu, B 2023, 'NPM1 mutation reprograms leukemic transcription network via reshaping TAD topology', Leukemia, vol. 37, no. 8, pp. 1732-1736. https://doi.org/10.1038/s41375-023-01942-9
2022
Luo, H, Zhu, G, Eshelman, MA, Fung, TK, Lai, Q, Wang, F, Zeisig, BB, Lesperance, J, Ma, X, Chen, S, Cesari, N, Cogle, C, Chen, B, Xu, B, Yang, FC, So, CWE, Qiu, Y, Xu, M & Huang, S 2022, 'HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia', Molecular cell, vol. 82, no. 4, pp. 833-851.e11. https://doi.org/10.1016/j.molcel.2022.01.014