Song Tan - Penn State Cancer Institute
Researcher Profile
Song Tan
Professor, Biochemistry & Molecular Biology
Scientific Program:Mechanisms of Carcinogenesis
Recent Publications
2024
Baier, AS, Gioacchini, N, Eek, P, Leith, EM, Tan, S & Peterson, CL 2024, 'Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C', eLife, vol. 13. https://doi.org/10.7554/eLife.94869
Xu, C, Kleinschmidt, H, Yang, J, Leith, EM, Johnson, J, Tan, S, Mahony, S & Bai, L 2024, 'Systematic dissection of sequence features affecting binding specificity of a pioneer factor reveals binding synergy between FOXA1 and AP-1', Molecular cell, vol. 84, no. 15, pp. 2838-2855.e10. https://doi.org/10.1016/j.molcel.2024.06.022
2023
Donovan, BT, Chen, H, Eek, P, Meng, Z, Jipa, C, Tan, S, Bai, L & Poirier, MG 2023, 'Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions', Molecular cell, vol. 83, no. 8, pp. 1251-1263.e6. https://doi.org/10.1016/j.molcel.2023.03.006
Chio, US, Rechiche, O, Bryll, AR, Zhu, J, Leith, EM, Feldman, JL, Peterson, CL, Tan, S & Armache, JP 2023, 'Cryo-EM structure of the human Sirtuin 6–nucleosome complex', Science Advances, vol. 9, no. 15, eadf7586. https://doi.org/10.1126/sciadv.adf7586
Namitz, KEW, Tan, S & Cosgrove, MS 2023, 'Hierarchical assembly of the MLL1 core complex regulates H3K4 methylation and is dependent on temperature and component concentration', Journal of Biological Chemistry, vol. 299, no. 2, 102874. https://doi.org/10.1016/j.jbc.2023.102874
2021
McGinty, RK & Tan, S 2021, 'Principles of nucleosome recognition by chromatin factors and enzymes', Current Opinion in Structural Biology, vol. 71, pp. 16-26. https://doi.org/10.1016/j.sbi.2021.05.006
Santilli, RT, Williamson, JE, Shibata, Y, Sowers, RP, Fleischman, AN & Tan, S 2021, 'The Penn State Protein Ladder system for inexpensive protein molecular weight markers', Scientific reports, vol. 11, no. 1, 16703. https://doi.org/10.1038/s41598-021-96051-x