Researcher Profile

Researcher Profile

Song Tan

Song Tan

Professor, Biochemistry & Molecular Biology
Scientific Program:Mechanisms of Carcinogenesis
sxt30@psu.edu

Research Interests

  • Nucleosomes
  • Histones
  • Yeasts
  • Proteins
  • Chromatin
  • DNA
  • Histone Acetyltransferases
  • Acetylation
  • Enzymes
  • Genes
  • Transcription Factors
  • Escherichia coli

Recent Publications

2020

Kim, SA, Zhu, J, Yennawar, N, Eek, P & Tan, S 2020, 'Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate', Molecular cell, vol. 78, no. 5, pp. 903-914.e4. https://doi.org/10.1016/j.molcel.2020.04.019
Lehmann, LC, Bacic, L, Hewitt, G, Brackmann, K, Sabantsev, A, Gaullier, G, Pytharopoulou, S, Degliesposti, G, Okkenhaug, H, Tan, S, Costa, A, Skehel, JM, Boulton, SJ & Deindl, S 2020, 'Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch', Cell Reports, vol. 33, no. 12, 108529. https://doi.org/10.1016/j.celrep.2020.108529
Espinola-Lopez, JM & Tan, S 2021, 'The Ada2/Ada3/Gcn5/Sgf29 histone acetyltransferase module', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1864, no. 2, 194629. https://doi.org/10.1016/j.bbagrm.2020.194629

2018

Sun, J, Paduch, M, Kim, SA, Kramer, RM, Barrios, AF, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, AA & Tan, S 2018, 'Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 40, pp. 10010-10015. https://doi.org/10.1073/pnas.1805343115

2017

Henrici, RC, Pecen, TJ, Johnston, JL & Tan, S 2017, 'The pPSU Plasmids for Generating DNA Molecular Weight Markers', Scientific reports, vol. 7, no. 1, 2438. https://doi.org/10.1038/s41598-017-02693-1

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