Researcher Profile

Researcher Profile

Song Tan

Song Tan

Professor, Biochemistry & Molecular Biology
Scientific Program:Mechanisms of Carcinogenesis

Research Interests

  • Nucleosomes
  • Histones
  • Proteins
  • Chromatin
  • Yeasts
  • DNA
  • Histone Acetyltransferases
  • Acetylation
  • Enzymes
  • Genes
  • Transcription Factors
  • Escherichia coli

Recent Publications


McGinty, RK & Tan, S 2021, 'Principles of nucleosome recognition by chromatin factors and enzymes', Current Opinion in Structural Biology, vol. 71, pp. 16-26.
Santilli, RT, Williamson, JE, Shibata, Y, Sowers, RP, Fleischman, AN & Tan, S 2021, 'The Penn State Protein Ladder system for inexpensive protein molecular weight markers', Scientific reports, vol. 11, no. 1, 16703.


Kim, SA, Zhu, J, Yennawar, N, Eek, P & Tan, S 2020, 'Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate', Molecular cell, vol. 78, no. 5, pp. 903-914.e4.
Lehmann, LC, Bacic, L, Hewitt, G, Brackmann, K, Sabantsev, A, Gaullier, G, Pytharopoulou, S, Degliesposti, G, Okkenhaug, H, Tan, S, Costa, A, Skehel, JM, Boulton, SJ & Deindl, S 2020, 'Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch', Cell Reports, vol. 33, no. 12, 108529.
Espinola-Lopez, JM & Tan, S 2021, 'The Ada2/Ada3/Gcn5/Sgf29 histone acetyltransferase module', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1864, no. 2, 194629.


Sun, J, Paduch, M, Kim, SA, Kramer, RM, Barrios, AF, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, AA & Tan, S 2018, 'Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 40, pp. 10010-10015.

Clinical Trials Search

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