Researcher Profile

Researcher Profile

Joseph C. Reese

Joseph C. Reese

Professor, Biochemistry & Molecular Biology
Scientific Program:Mechanisms of Carcinogenesis
jcr8@psu.edu

Research Interests

  • Yeasts
  • Genes
  • Nucleosomes
  • RNA Polymerase II
  • Transcriptional Activation
  • Proteins
  • Estrogen Receptors
  • Chromatin
  • DNA
  • Transcription Factor TFIID
  • Histones
  • Hormones

Recent Publications

2020

Huynh, MT, Yadav, SP, Reese, JC & Lee, TH 2020, 'Nucleosome Dynamics during Transcription Elongation', ACS chemical biology, vol. 15, no. 12, pp. 3133-3142. https://doi.org/10.1021/acschembio.0c00617

2019

Reese, JC 2019, 'Analysis of RNAPII complexes', Methods, vol. 159-160, pp. 1-3. https://doi.org/10.1016/j.ymeth.2019.06.007
Brooks Crickard, J & Reese, JC 2019, 'Biochemical methods to characterize RNA polymerase II elongation complexes', Methods, vol. 159-160, pp. 70-81. https://doi.org/10.1016/j.ymeth.2019.01.011
Jiang, H, Wolgast, M, Beebe, LM & Reese, JC 2019, 'Ccr4–not maintains genomic integrity by controlling the ubiquitylation and degradation of arrested RNAPII', Genes and Development, vol. 33, no. 11-12, pp. 705-717. https://doi.org/10.1101/gad.322453.118
Lee, J, Crickard, JB, Reese, JC & Lee, TH 2019, 'Single-molecule FRET method to investigate the dynamics of transcription elongation through the nucleosome by RNA polymerase II', Methods, vol. 159-160, pp. 51-58. https://doi.org/10.1016/j.ymeth.2019.01.009

2018

Miller, JE, Zhang, L, Jiang, H, Li, Y, Pugh, BF & Reese, JC 2018, 'Genome-wide mapping of decay factor-mRNA interactions in yeast identifies nutrient-responsive transcripts as targets of the deadenylase Ccr4', G3: Genes, Genomes, Genetics, vol. 8, no. 1, pp. 315-330. https://doi.org/10.1534/g3.117.300415
Boguta, M & Reese, JC 2018, 'Regulation of tRNA synthesis and modification in physiological conditions and disease', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1861, no. 4, pp. 283-284. https://doi.org/10.1016/j.bbagrm.2018.03.004

2017

Crickard, JB, Lee, J, Lee, TH & Reese, JC 2017, 'The elongation factor Spt4/5 regulates RNA polymerase II transcription through the nucleosome', Nucleic acids research, vol. 45, no. 11, pp. 6362-6374. https://doi.org/10.1093/nar/gkx220

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