Researcher Profile

Researcher Profile

Vishal Singh

Vishal Singh

Assistant Professor, Nutritional Sciences
Scientific Program:Mechanisms of Carcinogenesis

Research Interests

  • Inflammation
  • Lipocalin-2
  • Microbiota
  • Gastrointestinal Microbiome
  • Diet
  • Colitis
  • Atherosclerosis
  • Cholesterol
  • turmeric extract
  • Liver
  • Interleukin-1
  • Macrophages

Recent Publications


Lee, LH, Wong, SH, Chin, SF, Singh, V & Ab Mutalib, NS 2021, 'Editorial: Human Microbiome: Symbiosis to Pathogenesis', Frontiers in Microbiology, vol. 12, 605783.


Singh, V & Vijay-Kumar, M 2020, 'Beneficial and detrimental effects of processed dietary fibers on intestinal and liver health: Health benefits of refined dietary fibers need to be redefined!', Gastroenterology Report, vol. 8, no. 2, pp. 85-89.
Singh, V, Galla, S, Golonka, RM, Patterson, AD, Chassaing, B, Joe, B & Vijay-Kumar, M 2020, 'Lipocalin 2 deficiency-induced gut microbiota dysbiosis evokes metabolic syndrome in aged mice', Physiological genomics, vol. 52, no. 8, pp. 314-321.
Nettleford, SK, Zhao, L, Qian, F, Herold, M, Arner, B, Desai, D, Amin, S, Xiong, N, Singh, V, Carlson, BA & Prabhu, KS 2020, 'The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation', Frontiers in Nutrition, vol. 7, 96.
Singh, V, Gowda, CP, Singh, V, Ganapathy, AS, Karamchandani, DM, Eshelman, MA, Yochum, GS, Nighot, P & Spiegelman, VS 2020, 'The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating Occludin expression', Journal of Biological Chemistry, vol. 295, no. 25.
Singh, V, Yeoh, BS, Abokor, AA, Golonka, RM, Tian, Y, Patterson, AD, Joe, B, Heikenwalder, M & Vijay-Kumar, M 2020, 'Vancomycin prevents fermentable fiber-induced liver cancer in mice with dysbiotic gut microbiota', Gut microbes, vol. 11, no. 4, pp. 1077-1091.


Singh, A, Singh, V, Tiwari, RL, Chandra, T, Kumar, A, Dikshit, M & Barthwal, MK 2019, 'Correction to: The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes (Cellular & Molecular Immunology, (2016), 13, 6, (745-763), 10.1038/cmi.2015.62)', Cellular and Molecular Immunology, vol. 16, no. 12, pp. 946.
Singh, V, Yeoh, BS, Walker, RE, Xiao, X, Saha, P, Golonka, RM, Cai, J, Bretin, ACA, Cheng, X, Liu, Q, Flythe, MD, Chassaing, B, Shearer, GC, Patterson, AD, Gewirtz, AT & Vijay-Kumar, M 2019, 'Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation', Gut, vol. 68, no. 10, pp. 1801-1812.
Saha, P, Yeoh, BS, Xiao, X, Golonka, RM, Singh, V, Wang, Y & Vijay-Kumar, M 2019, 'PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium', Mucosal Immunology, vol. 12, no. 3, pp. 761-771.


Singh, V, Yeoh, BS, Chassaing, B, Xiao, X, Saha, P, Aguilera Olvera, R, Lapek, JD, Zhang, L, Wang, WB, Hao, S, Flythe, MD, Gonzalez, DJ, Cani, PD, Conejo-Garcia, JR, Xiong, N, Kennett, MJ, Joe, B, Patterson, AD, Gewirtz, AT & Vijay-Kumar, M 2018, 'Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer', Cell, vol. 175, no. 3, pp. 679-694.e22.
Xiao, X, Saha, P, Yeoh, BS, Hipp, JA, Singh, V & Vijay-Kumar, M 2018, 'Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects', Journal of Nutritional Biochemistry, vol. 62, pp. 28-34.
Chakraborty, S, Galla, S, Cheng, X, Yeo, JY, Mell, B, Singh, V, Yeoh, BS, Saha, P, Mathew, AV, Vijay-Kumar, M & Joe, B 2018, 'Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension', Cell Reports, vol. 25, no. 3, pp. 677-689.e4.
Kanshana, JS, Rebello, SC, Pathak, P, Kanuri, BN, Aggarwal, H, Srivastava, V, Khanna, V, Singh, V, Jagavelu, K, Barthwal, MK & Dikshit, M 2018, 'Standardized fraction of Xylocarpus moluccensis fruits improve vascular relaxation and plaque stability in dyslipidemic models of atherosclerosis', Journal of Ethnopharmacology, vol. 213, pp. 81-91.


Saha, P, Yeoh, BS, Olvera, RA, Xiao, X, Singh, V, Awasthi, D, Subramanian, BC, Chen, Q, Dikshit, M, Wang, Y, Parent, CA & Vijay-Kumar, M 2017, 'Bacterial siderophores hijack neutrophil functions', Journal of Immunology, vol. 198, no. 11, pp. 4293-4303.
Singh, V, Yeoh, BS, Nilsen-Hamilton, M, Berger, T, Mak, TW & Vijay-Kumar, M 2017, 'Data on IL-10R neutralization-induced chronic colitis in Lipocalin 2 deficient mice on BALB/c background', Data in Brief, vol. 11, pp. 588-592.
Saha, P, Chassaing, B, Yeoh, BS, Viennois, E, Xiao, X, Kennett, MJ, Singh, V & Vijay-Kumar, M 2017, 'Ectopic Expression of Innate Immune Protein, Lipocalin-2, in Lactococcus lactis Protects Against Gut and Environmental Stressors', Inflammatory bowel diseases, vol. 23, no. 7, pp. 1120-1132.
Zou, J, Chassaing, B, Singh, V, Pellizzon, M, Ricci, M, Fythe, MD, Kumar, MV & Gewirtz, AT 2018, 'Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health', Cell Host and Microbe, vol. 23, no. 1, pp. 41-53.e4.
Xiao, X, Yeoh, BS, Saha, P, Tian, Y, Singh, V, Patterson, AD & Vijay-Kumar, M 2017, 'Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice', Journal of Nutritional Biochemistry, vol. 41, pp. 25-33.
Kanshana, JS, Khanna, V, Singh, V, Jain, M, Misra, A, Kumar, S, Farooqui, M, Barthwal, MK & Dikshit, M 2017, 'Progression and Characterization of the Accelerated Atherosclerosis in Iliac Artery of New Zealand White Rabbits: Effect of Simvastatin', Journal of Cardiovascular Pharmacology, vol. 69, no. 5, pp. 314-325.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)