Researcher Profile

Researcher Profile

Joshua Kellogg

Joshua Kellogg

Assistant Professor, Veterinary and Biomedical Sciences
Scientific Program:Mechanisms of Carcinogenesis
jjk6146@psu.edu

Research Interests

  • Metabolomics
  • Hydrastis
  • Biological Products
  • Mass Spectrometry
  • In Vitro Techniques
  • Datasets
  • Camellia sinensis
  • Tea
  • Seaweed
  • Principal Component Analysis
  • Biological Assay
  • Liquid Chromatography

Recent Publications

2021

Clark, TN, Houriet, J, Vidar, WS, Kellogg, JJ, Todd, DA, Cech, NB & Linington, RG 2021, 'Interlaboratory Comparison of Untargeted Mass Spectrometry Data Uncovers Underlying Causes for Variability', Journal of Natural Products, vol. 84, no. 3, pp. 824-835. https://doi.org/10.1021/acs.jnatprod.0c01376

2020

Nguyen, JT, Tian, DD, Tanna, RS, Hadi, DL, Bansal, S, Calamia, JC, Arian, CM, Shireman, LM, Molnár, B, Horváth, M, Kellogg, JJ, Layton, ME, White, JR, Cech, NB, Boyce, RD, Unadkat, JD, Thummel, KE & Paine, MF 2021, 'Assessing Transporter-Mediated Natural Product-Drug Interactions Via In vitro-In Vivo Extrapolation: Clinical Evaluation With a Probe Cocktail', Clinical pharmacology and therapeutics, vol. 109, no. 5, pp. 1342-1352. https://doi.org/10.1002/cpt.2107
Todd, DA, Kellogg, JJ, Wallace, ED, Khin, M, Flores-Bocanegra, L, Tanna, RS, McIntosh, S, Raja, HA, Graf, TN, Hemby, SE, Paine, MF, Oberlies, NH & Cech, NB 2020, 'Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions', Scientific reports, vol. 10, no. 1, 19158. https://doi.org/10.1038/s41598-020-76119-w
Khin, M, Cech, NB, Kellogg, JJ & Caesar, LK 2020, 'Chemical evaluation of the effects of storage conditions on the botanical goldenseal using marker-based and metabolomics approaches', Yale Journal of Biology and Medicine, vol. 93, no. 2, pp. 265-275.
Wallace, ED, Todd, DA, Harnly, JM, Cech, NB & Kellogg, JJ 2020, 'Identification of adulteration in botanical samples with untargeted metabolomics', Analytical and Bioanalytical Chemistry, vol. 412, no. 18, pp. 4273-4286. https://doi.org/10.1007/s00216-020-02678-6
Kellogg, J & Kang, S 2020, 'Metabolomics, an essential tool in exploring and harnessing microbial chemical ecology', Phytobiomes Journal, vol. 4, no. 3, pp. 195-210. https://doi.org/10.1094/PBIOMES-04-20-0032-RVW
Liigand, J, Wang, T, Kellogg, J, Smedsgaard, J, Cech, N & Kruve, A 2020, 'Quantification for non-targeted LC/MS screening without standard substances', Scientific reports, vol. 10, no. 1, 5808. https://doi.org/10.1038/s41598-020-62573-z
Flores-Bocanegra, L, Raja, HA, Graf, TN, Augustinović, M, Wallace, ED, Hematian, S, Kellogg, JJ, Todd, DA, Cech, NB & Oberlies, NH 2020, 'The Chemistry of Kratom [ Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids', Journal of Natural Products, vol. 83, no. 7, pp. 2165-2177. https://doi.org/10.1021/acs.jnatprod.0c00257

2019

Curtin, P, Kellogg, J, Cech, N & Gennings, C 2021, 'A random subset implementation of weighted quantile sum (WQSRS) regression for analysis of high-dimensional mixtures', Communications in Statistics: Simulation and Computation, vol. 50, no. 4, pp. 1099-1114. https://doi.org/10.1080/03610918.2019.1577971
Kellogg, JJ, Kvalheim, OM & Cech, NB 2020, 'Composite score analysis for unsupervised comparison and network visualization of metabolomics data', Analytica Chimica Acta, vol. 1095, pp. 38-47. https://doi.org/10.1016/j.aca.2019.10.029
Caesar, LK, Kellogg, JJ, Kvalheim, OM & Cech, NB 2019, 'Opportunities and Limitations for Untargeted Mass Spectrometry Metabolomics to Identify Biologically Active Constituents in Complex Natural Product Mixtures', Journal of Natural Products, vol. 82, no. 3, pp. 469-484. https://doi.org/10.1021/acs.jnatprod.9b00176
Kellogg, JJ, Paine, MF, McCune, JS, Oberlies, NH & Cech, NB 2019, 'Selection and characterization of botanical natural products for research studies: A NaPDI center recommended approach', Natural Product Reports, vol. 36, no. 8, pp. 1196-1221. https://doi.org/10.1039/c8np00065d

2018

Britton, ER, Kellogg, JJ, Kvalheim, OM & Cech, NB 2018, 'Biochemometrics to Identify Synergists and Additives from Botanical Medicines: A Case Study with Hydrastis canadensis (Goldenseal)', Journal of Natural Products, vol. 81, no. 3, pp. 484-493. https://doi.org/10.1021/acs.jnatprod.7b00654
Wallace, ED, Oberlies, NH, Cech, NB & Kellogg, JJ 2018, 'Detection of adulteration in Hydrastis canadensis (goldenseal) dietary supplements via untargeted mass spectrometry-based metabolomics', Food and Chemical Toxicology, vol. 120, pp. 439-447. https://doi.org/10.1016/j.fct.2018.07.033
Tian, DD, Kellogg, JJ, Okut, N, Oberlies, NH, Cech, NB, Shen, DD, McCune, JS & Paine, MF 2018, 'Identification of intestinal UDP-Glucuronosyltransferase inhibitors in green tea (Camellia sinensis) using a biochemometric approach: Application to raloxifene as a test drug via in vitro to in vivo extrapolation', Drug Metabolism and Disposition, vol. 46, no. 5, pp. 552-560. https://doi.org/10.1124/dmd.117.079491
Caesar, LK, Kellogg, JJ, Kvalheim, OM, Cech, RA & Cech, NB 2018, 'Integration of Biochemometrics and Molecular Networking to Identify Antimicrobials in Angelica keiskei', Planta Medica, vol. 84, no. 9-10, B1077, pp. 721-728. https://doi.org/10.1055/a-0590-5223

2017

Kellogg, JJ, Graf, TN, Paine, MF, McCune, JS, Kvalheim, OM, Oberlies, NH & Cech, NB 2017, 'Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study', Journal of Natural Products, vol. 80, no. 5, pp. 1457-1466. https://doi.org/10.1021/acs.jnatprod.6b01156
Kellogg, JJ, Wallace, ED, Graf, TN, Oberlies, NH & Cech, NB 2017, 'Conventional and accelerated-solvent extractions of green tea (camellia sinensis) for metabolomics-based chemometrics', Journal of Pharmaceutical and Biomedical Analysis, vol. 145, pp. 604-610. https://doi.org/10.1016/j.jpba.2017.07.027
Kellogg, JJ & Raja, HA 2017, 'Endolichenic fungi: a new source of rich bioactive secondary metabolites on the horizon', Phytochemistry Reviews, vol. 16, no. 2, pp. 271-293. https://doi.org/10.1007/s11101-016-9473-1

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)