Researcher Profile

Researcher Profile

Joshua Kellogg

Joshua Kellogg

Assistant Professor, Veterinary and Biomedical Sciences
Scientific Program:Mechanisms of Carcinogenesis

Research Interests

  • Metabolomics
  • Hydrastis
  • Biological Products
  • Mass Spectrometry
  • In Vitro Techniques
  • Datasets
  • Dietary Supplements
  • Camellia sinensis
  • Tea
  • Seaweed
  • Principal Component Analysis
  • Biological Assay

Recent Publications


Abraham, EJ & Kellogg, JJ 2021, 'Chemometric-Guided Approaches for Profiling and Authenticating Botanical Materials', Frontiers in Nutrition, vol. 8, 780228.
Clark, TN, Houriet, J, Vidar, WS, Kellogg, JJ, Todd, DA, Cech, NB & Linington, RG 2021, 'Interlaboratory Comparison of Untargeted Mass Spectrometry Data Uncovers Underlying Causes for Variability', Journal of Natural Products, vol. 84, no. 3, pp. 824-835.


Nguyen, JT, Tian, DD, Tanna, RS, Hadi, DL, Bansal, S, Calamia, JC, Arian, CM, Shireman, LM, Molnár, B, Horváth, M, Kellogg, JJ, Layton, ME, White, JR, Cech, NB, Boyce, RD, Unadkat, JD, Thummel, KE & Paine, MF 2021, 'Assessing Transporter-Mediated Natural Product-Drug Interactions Via In vitro-In Vivo Extrapolation: Clinical Evaluation With a Probe Cocktail', Clinical pharmacology and therapeutics, vol. 109, no. 5, pp. 1342-1352.
Todd, DA, Kellogg, JJ, Wallace, ED, Khin, M, Flores-Bocanegra, L, Tanna, RS, McIntosh, S, Raja, HA, Graf, TN, Hemby, SE, Paine, MF, Oberlies, NH & Cech, NB 2020, 'Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions', Scientific reports, vol. 10, no. 1, 19158.
Khin, M, Cech, NB, Kellogg, JJ & Caesar, LK 2020, 'Chemical evaluation of the effects of storage conditions on the botanical goldenseal using marker-based and metabolomics approaches', Yale Journal of Biology and Medicine, vol. 93, no. 2, pp. 265-275.
Wallace, ED, Todd, DA, Harnly, JM, Cech, NB & Kellogg, JJ 2020, 'Identification of adulteration in botanical samples with untargeted metabolomics', Analytical and Bioanalytical Chemistry, vol. 412, no. 18, pp. 4273-4286.
Kellogg, J & Kang, S 2020, 'Metabolomics, an essential tool in exploring and harnessing microbial chemical ecology', Phytobiomes Journal, vol. 4, no. 3, pp. 195-210.
Liigand, J, Wang, T, Kellogg, J, Smedsgaard, J, Cech, N & Kruve, A 2020, 'Quantification for non-targeted LC/MS screening without standard substances', Scientific reports, vol. 10, no. 1, 5808.
Flores-Bocanegra, L, Raja, HA, Graf, TN, Augustinović, M, Wallace, ED, Hematian, S, Kellogg, JJ, Todd, DA, Cech, NB & Oberlies, NH 2020, 'The Chemistry of Kratom [ Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids', Journal of Natural Products, vol. 83, no. 7, pp. 2165-2177.


Curtin, P, Kellogg, J, Cech, N & Gennings, C 2021, 'A random subset implementation of weighted quantile sum (WQSRS) regression for analysis of high-dimensional mixtures', Communications in Statistics: Simulation and Computation, vol. 50, no. 4, pp. 1099-1114.
Kellogg, JJ, Kvalheim, OM & Cech, NB 2020, 'Composite score analysis for unsupervised comparison and network visualization of metabolomics data', Analytica Chimica Acta, vol. 1095, pp. 38-47.
Caesar, LK, Kellogg, JJ, Kvalheim, OM & Cech, NB 2019, 'Opportunities and Limitations for Untargeted Mass Spectrometry Metabolomics to Identify Biologically Active Constituents in Complex Natural Product Mixtures', Journal of Natural Products, vol. 82, no. 3, pp. 469-484.
Kellogg, JJ, Paine, MF, McCune, JS, Oberlies, NH & Cech, NB 2019, 'Selection and characterization of botanical natural products for research studies: A NaPDI center recommended approach', Natural Product Reports, vol. 36, no. 8, pp. 1196-1221.


Britton, ER, Kellogg, JJ, Kvalheim, OM & Cech, NB 2018, 'Biochemometrics to Identify Synergists and Additives from Botanical Medicines: A Case Study with Hydrastis canadensis (Goldenseal)', Journal of Natural Products, vol. 81, no. 3, pp. 484-493.
Wallace, ED, Oberlies, NH, Cech, NB & Kellogg, JJ 2018, 'Detection of adulteration in Hydrastis canadensis (goldenseal) dietary supplements via untargeted mass spectrometry-based metabolomics', Food and Chemical Toxicology, vol. 120, pp. 439-447.
Tian, DD, Kellogg, JJ, Okut, N, Oberlies, NH, Cech, NB, Shen, DD, McCune, JS & Paine, MF 2018, 'Identification of intestinal UDP-Glucuronosyltransferase inhibitors in green tea (Camellia sinensis) using a biochemometric approach: Application to raloxifene as a test drug via in vitro to in vivo extrapolation', Drug Metabolism and Disposition, vol. 46, no. 5, pp. 552-560.
Caesar, LK, Kellogg, JJ, Kvalheim, OM, Cech, RA & Cech, NB 2018, 'Integration of Biochemometrics and Molecular Networking to Identify Antimicrobials in Angelica keiskei', Planta Medica, vol. 84, no. 9-10, B1077, pp. 721-728.

Clinical Trials Search

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