Researcher Profile

Researcher Profile

Andrea Manni, MD

Andrea Manni, MD

Professor, Department of Medicine
Chief, Division of Endocrinology and Diabetes
Scientific Program:Cancer Control

Research Interests

  • Breast Neoplasms
  • Neoplasms
  • Polyamines
  • Therapeutics
  • Growth
  • Hormones
  • Tamoxifen
  • Eflornithine
  • Estrogens
  • Estrogen Receptor Modulators
  • Prolactin
  • Estradiol

Recent Publications


El-Bayoumy, K & Manni, A 2019, 'Customized Prevention Trials Could Resolve the Controversy of the Effects of Omega-3 Fatty Acids on Cancer', Nutrition and cancer.
Sun, Y-W, Xu, H, Benitez, G, Chen, KM, Stanley, A, Stanley, B, Zhu, J, Thompson, H, Manni, A & El-Bayoumy, K 2019, 'Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women', Journal of Proteome Research, vol. 18, no. 9, pp. 3461-3469.


Manni, A, El-Bayoumy, K & Thompson, H 2018, 'Docosahexaenoic acid in combination with dietary energy restriction for reducing the risk of obesity related breast cancer', International journal of molecular sciences, vol. 19, no. 1, 28.


Manni, A, Richie, J, Schetter, S, Calcagnotto, A, Trushin, N, Aliaga, C & El-Bayoumy, K 2017, 'Stearoyl-CoA desaturase-1, a novel target of omega-3 fatty acids for reducing breast cancer risk in obese postmenopausal women', European Journal of Clinical Nutrition, vol. 71, no. 6, pp. 762-765.


Skibinski, CG, Das, A, Chen, K-M, Liao, JJ, Manni, A, Kester, M & El-Bayoumy, K 2016, 'A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines', Chemico-Biological Interactions, vol. 252, pp. 1-8.
Manni, A & El-Bayoumy, K 2016, 'Do omega-3 fatty acids reduce the risk of breast cancer in postmenopausal obese women?', Expert Review of Endocrinology and Metabolism, vol. 11, no. 5, pp. 365-367.
Sandhu, N, Schetter, SE, Liao, J, Hartman, TJ, Richie, JP, McGinley, J, Thompson, HJ, Prokopczyk, B, DuBrock, C, Signori, C, Hamilton, C, Calcagnotto, A, Trushin, N, Aliaga, C, Demers, LM, El-Bayoumy, K & Manni, A 2016, 'Influence of obesity on breast density reduction by omega-3 fatty acids: Evidence from a randomized clinical trial', Cancer Prevention Research, vol. 9, no. 4, pp. 275-282.
for the VALUES Consortium 2017, 'The relationship between oestrogen and executive functioning in ALS females with emerging Frontotemporal Lobar Degeneration (FTLD) supports a neuroendocrine model of FTLD attenuation', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol. 18, no. 1-2, pp. 74-85.
Manni, A, El-Bayoumy, K, Skibinski, CG, Thompson, HJ, Santucci-Pereira, J, Bidinotto, LT & Russo, J 2016, The role of omega-3 fatty acids in breast cancer prevention. in Trends in Breast Cancer Prevention. Springer International Publishing, pp. 51-81.


Agito, K & Manni, A 2015, 'Acute pancreatitis induced by methimazole in a patient with subclinical hyperthyroidism', Journal of Investigative Medicine High Impact Case Reports, vol. 3, no. 2.
Manni, A, El-Bayoumy, K, Skibinski, CG, Thompson, HJ, Santucci-Pereira, J, Bidinotto, LT & Russo, J 2015, 'Combination of antiestrogens and Omega-3 fatty acids for breast cancer prevention' BioMed Research International, vol. 2015, 638645.
Dillard, J, Meyer, BJ, Solomon, DH & Manni, A 2015, 'Factors associated with participation in a prevention trial aimed at reducing biomarkers of breast cancer risk', Patient Education and Counseling, vol. 98, no. 5, pp. 640-644.
Turbitt, WJ, Black, AJ, Collins, SD, Meng, H, Xu, H, Washington, S, Aliaga, C, El-Bayoumy, K, Manni, A & Rogers, CJ 2015, 'Fish Oil Enhances T Cell Function and Tumor Infiltration and Is Correlated with a Cancer Prevention Effect in HER-2/neu but Not PyMT Transgenic Mice', Nutrition and cancer, vol. 67, no. 6, pp. 965-975.
Haakenson, JK, Khokhlatchev, AV, Choi, YJ, Linton, SS, Zhang, P, Zaki, PM, Fu, C, Cooper, T, Manni, A, Zhu, J, Fox, TE, Dong, C & Kester, M 2015, 'Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells', Journal of Biological Chemistry, vol. 290, no. 13, pp. 8632-8643.
Portela, RA, Choby, GW, Manni, A, Campbell, D, Crist, H & Goldenberg, D 2015, 'Unusual sites of metastasis of papillary thyroid cancer: Case series and review of the literature' Ear, Nose and Throat Journal, vol. 94, no. 8, pp. E43.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)