Researcher Profile

Researcher Profile

Andrea Manni, MD

Andrea Manni, MD

Professor, Department of Medicine
Chief, Division of Endocrinology and Diabetes
Scientific Program:Cancer Control
axm15@psu.edu

Research Interests

  • Breast Neoplasms
  • Neoplasms
  • Polyamines
  • Therapeutics
  • Growth
  • Hormones
  • Tamoxifen
  • Eflornithine
  • Estrogens
  • Estrogen Receptor Modulators
  • Prolactin
  • Estradiol

Recent Publications

2019

El-Bayoumy, K & Manni, A 2019, 'Customized Prevention Trials Could Resolve the Controversy of the Effects of Omega-3 Fatty Acids on Cancer', Nutrition and cancer. https://doi.org/10.1080/01635581.2019.1651348
Sun, Y-W, Xu, H, Benitez, G, Chen, KM, Stanley, A, Stanley, B, Zhu, J, Thompson, H, Manni, A & El-Bayoumy, K 2019, 'Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women', Journal of Proteome Research, vol. 18, no. 9, pp. 3461-3469. https://doi.org/10.1021/acs.jproteome.9b00356

2018

Manni, A, El-Bayoumy, K & Thompson, H 2018, 'Docosahexaenoic acid in combination with dietary energy restriction for reducing the risk of obesity related breast cancer', International journal of molecular sciences, vol. 19, no. 1, 28. https://doi.org/10.3390/ijms19010028

2017

Manni, A, Richie, J, Schetter, S, Calcagnotto, A, Trushin, N, Aliaga, C & El-Bayoumy, K 2017, 'Stearoyl-CoA desaturase-1, a novel target of omega-3 fatty acids for reducing breast cancer risk in obese postmenopausal women', European Journal of Clinical Nutrition, vol. 71, no. 6, pp. 762-765. https://doi.org/10.1038/ejcn.2016.273

2016

Skibinski, CG, Das, A, Chen, K-M, Liao, JJ, Manni, A, Kester, M & El-Bayoumy, K 2016, 'A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines', Chemico-Biological Interactions, vol. 252, pp. 1-8. https://doi.org/10.1016/j.cbi.2016.03.035
Manni, A & El-Bayoumy, K 2016, 'Do omega-3 fatty acids reduce the risk of breast cancer in postmenopausal obese women?', Expert Review of Endocrinology and Metabolism, vol. 11, no. 5, pp. 365-367. https://doi.org/10.1080/17446651.2016.1220296
Sandhu, N, Schetter, SE, Liao, J, Hartman, TJ, Richie, JP, McGinley, J, Thompson, HJ, Prokopczyk, B, DuBrock, C, Signori, C, Hamilton, C, Calcagnotto, A, Trushin, N, Aliaga, C, Demers, LM, El-Bayoumy, K & Manni, A 2016, 'Influence of obesity on breast density reduction by omega-3 fatty acids: Evidence from a randomized clinical trial', Cancer Prevention Research, vol. 9, no. 4, pp. 275-282. https://doi.org/10.1158/1940-6207.CAPR-15-0235
for the VALUES Consortium 2017, 'The relationship between oestrogen and executive functioning in ALS females with emerging Frontotemporal Lobar Degeneration (FTLD) supports a neuroendocrine model of FTLD attenuation', Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol. 18, no. 1-2, pp. 74-85. https://doi.org/10.1080/21678421.2016.1249487
Manni, A, El-Bayoumy, K, Skibinski, CG, Thompson, HJ, Santucci-Pereira, J, Bidinotto, LT & Russo, J 2016, The role of omega-3 fatty acids in breast cancer prevention. in Trends in Breast Cancer Prevention. Springer International Publishing, pp. 51-81. https://doi.org/10.1007/978-3-319-27135-4_3

2015

Agito, K & Manni, A 2015, 'Acute pancreatitis induced by methimazole in a patient with subclinical hyperthyroidism', Journal of Investigative Medicine High Impact Case Reports, vol. 3, no. 2. https://doi.org/10.1177/2324709615592229
Manni, A, El-Bayoumy, K, Skibinski, CG, Thompson, HJ, Santucci-Pereira, J, Bidinotto, LT & Russo, J 2015, 'Combination of antiestrogens and Omega-3 fatty acids for breast cancer prevention' BioMed Research International, vol. 2015, 638645. https://doi.org/10.1155/2015/638645
Dillard, J, Meyer, BJ, Solomon, DH & Manni, A 2015, 'Factors associated with participation in a prevention trial aimed at reducing biomarkers of breast cancer risk', Patient Education and Counseling, vol. 98, no. 5, pp. 640-644. https://doi.org/10.1016/j.pec.2015.01.007
Turbitt, WJ, Black, AJ, Collins, SD, Meng, H, Xu, H, Washington, S, Aliaga, C, El-Bayoumy, K, Manni, A & Rogers, CJ 2015, 'Fish Oil Enhances T Cell Function and Tumor Infiltration and Is Correlated with a Cancer Prevention Effect in HER-2/neu but Not PyMT Transgenic Mice', Nutrition and cancer, vol. 67, no. 6, pp. 965-975. https://doi.org/10.1080/01635581.2015.1060351
Haakenson, JK, Khokhlatchev, AV, Choi, YJ, Linton, SS, Zhang, P, Zaki, PM, Fu, C, Cooper, T, Manni, A, Zhu, J, Fox, TE, Dong, C & Kester, M 2015, 'Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells', Journal of Biological Chemistry, vol. 290, no. 13, pp. 8632-8643. https://doi.org/10.1074/jbc.M114.609677
Portela, RA, Choby, GW, Manni, A, Campbell, D, Crist, H & Goldenberg, D 2015, 'Unusual sites of metastasis of papillary thyroid cancer: Case series and review of the literature' Ear, Nose and Throat Journal, vol. 94, no. 8, pp. E43.

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)