Researcher Profile

Researcher Profile

Justin Pritchard

Justin Pritchard

Assistant Professor, Biomedical Engineering
Scientific Program:Mechanisms of Carcinogenesis

Research Interests

  • Neoplasms
  • Therapeutics
  • Pharmaceutical Preparations
  • Growth
  • Genes
  • Genome
  • Mutation
  • Leukemia
  • Drug Resistance
  • Drug Combinations
  • Mycobacterium
  • Small Interfering RNA

Recent Publications


Laencina, L, Dubois, V, Le Moigne, V, Viljoen, A, Majlessi, L, Pritchard, J, Bernut, A, Piel, L, Roux, AL, Gaillard, JL, Lombard, B, Loew, D, Rubin, EJ, Brosch, R, Kremer, L, Herrmann, JL & Girard-Misguich, F 2018, 'Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 5, pp. E1002-E1011.
Gozgit, JM, Chen, TH, Song, Y, Wardwell, S, Wang, F, Cai, J, Li, H, Edgren, H, Rivera, VM & Pritchard, J 2018, 'RET fusions observed in lung and colorectal cancers are sensitive to ponatinib', Oncotarget, vol. 9, no. 51, pp. 29654-29664.
Schmitt, MW, Pritchard, J, Leighow, SM, Aminov, BI, Beppu, L, Kim, DS, Hodgson, JG, Rivera, VM, Loeb, LA & Radich, JP 2018, 'Single-molecule sequencing reveals patterns of preexisting drug resistance that suggest treatment strategies in Philadelphia-positive leukemias', Clinical Cancer Research, vol. 24, no. 21, pp. 5321-5334.


Bruno, PM, Liu, Y, Park, GY, Murai, J, Koch, CE, Eisen, TJ, Pritchard, J, Pommier, Y, Lippard, SJ & Hemann, MT 2017, 'A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress', Nature Medicine, vol. 23, no. 4, pp. 461-471.
Rock, JM, Hopkins, FF, Chavez, A, Diallo, M, Chase, MR, Gerrick, ER, Pritchard, J, Church, GM, Rubin, EJ, Sassetti, CM, Schnappinger, D & Fortune, SM 2017, 'Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform', Nature Microbiology, vol. 2, 16274.


Zhao, B, Sedlak, JC, Srinivas, R, Creixell, P, Pritchard, J, Tidor, B, Lauffenburger, DA & Hemann, MT 2016, 'Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution', Cell, vol. 165, no. 1, pp. 234-246.
Zhao, B & Pritchard, J 2016, 'Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes', PLoS genetics, vol. 12, no. 6, e1006081.


Meacham, CE, Lawton, LN, Soto-Feliciano, YM, Pritchard, J, Joughin, BA, Ehrenberger, T, Fenouille, N, Zuber, J, Williams, RT, Young, RA & Hemann, MT 2015, 'A genome-scale in vivo loss-of-function screen identifies phf6 as a lineage-specific regulator of leukemia cell growth', Genes and Development, vol. 29, no. 5, pp. 483-488.
Baker, T, Nerle, S, Pritchard, J, Zhao, B, Rivera, VM, Garner, A & Gonzalvez, F 2015, 'Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors', Oncotarget, vol. 6, no. 32, pp. 32646-32655.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)