Researcher Profile

Researcher Profile

Edward P. O'Brien, Jr., PhD

Edward P. O'Brien, Jr., PhD

Assistant Professor, Chemistry
Scientific Program:Mechanisms of Carcinogenesis
Disease Teams:
Institute for CyberScience (ICS) - Co-hire

Research Interests

  • Proteins
  • Protein Folding
  • Ribosomes
  • Codon
  • Peptides
  • Molecular Models
  • Messenger RNA
  • Temperature
  • Urea
  • Proteome
  • Thermodynamics
  • Guanidine

Recent Publications


Leininger, SE, Narayan, K, Deutsch, C & O'Brien, Jr., EP 2019, 'Mechanochemistry in Translation', Biochemistry.






Nissley, DA & O'Brien, Jr., EP 2016, 'Altered co-translational processing plays a role in huntington’s pathogenesis-A hypothesis', Frontiers in Molecular Neuroscience, vol. 9, no. JUL, 54.


Caniparoli, L & O'Brien, Jr., EP 2015, 'Modeling the effect of codon translation rates on co-translational protein folding mechanisms of arbitrary complexity', Journal of Chemical Physics, vol. 142, no. 14, 145102.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)