Researcher Profile

Researcher Profile

Edward P. O'Brien, Jr., PhD

Edward P. O'Brien, Jr., PhD

Assistant Professor, Chemistry
Scientific Program:Mechanisms of Carcinogenesis
Disease Teams:
Institute for CyberScience (ICS) - Co-hire
epo2@psu.edu

Research Interests

  • Proteins
  • Protein Folding
  • Ribosomes
  • Codon
  • Peptides
  • Molecular Models
  • Messenger RNA
  • Temperature
  • Urea
  • Proteome
  • Thermodynamics
  • Guanidine

Recent Publications

2019

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Leininger, SE, Narayan, K, Deutsch, C & O'Brien, Jr., EP 2019, 'Mechanochemistry in Translation', Biochemistry. https://doi.org/10.1021/acs.biochem.9b00260

2018

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2017

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2016

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Nissley, DA & O'Brien, Jr., EP 2016, 'Altered co-translational processing plays a role in huntington’s pathogenesis-A hypothesis', Frontiers in Molecular Neuroscience, vol. 9, no. JUL, 54. https://doi.org/10.3389/fnmol.2016.00054
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2015

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Caniparoli, L & O'Brien, Jr., EP 2015, 'Modeling the effect of codon translation rates on co-translational protein folding mechanisms of arbitrary complexity', Journal of Chemical Physics, vol. 142, no. 14, 145102. https://doi.org/10.1063/1.4916914

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