Gustavo Alberto Nader - Penn State Cancer Institute
Researcher Profile
Gustavo Alberto Nader
Professor, Kinesiology
Associate Professor, Kinesiology
Associate Professor, Kinesiology
Scientific Program:Mechanisms of Carcinogenesis
Research Interests
- Muscles
- Skeletal Muscle
- Hypertrophy
- Proteins
- Exercise
- Gene Expression
- Skeletal Muscle Fibers
- Genes
- Growth
- Ribosomal DNA
- Resistance Training
- Phosphorylation
Recent Publications
2023
Roberts, MD, McCarthy, JJ, Hornberger, TA, Phillips, SM, Mackey, AL, Nader, GA, Boppart, MD, Kavazis, AN, Reidy, PT, Ogasawara, R, Libardi, CA, Ugrinowitsch, C, Booth, FW & Esser, KA 2023, 'Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions', Physiological Reviews. https://doi.org/10.1152/physrev.00039.2022
2022
Belcher, DJ, Guitart, M, Hain, B, Kim, HG, Waning, D, Barreiro, E & Nader, GA 2022, 'LP07 and LLC preclinical models of lung cancer induce divergent anabolic deficits and expression of pro-inflammatory effectors of muscle wasting', Journal of applied physiology, vol. 133, no. 6, pp. 1260-1272. https://doi.org/10.1152/japplphysiol.00246.2022
Kim, HG, Huot, JR, Pin, F, Belcher, DJ, Bonetto, A & Nader, GA 2022, 'Metastatic or xenograft colorectal cancer models induce divergent anabolic deficits and expression of pro-inflammatory effectors of muscle wasting in a tumor-type-dependent manner', Journal of applied physiology, vol. 133, no. 6, pp. 1273-1283. https://doi.org/10.1152/japplphysiol.00247.2022
2021
Guo, B, Bennet, D, Belcher, DJ, Kim, HG & Nader, GA 2021, 'Chemotherapy agents reduce protein synthesis and ribosomal capacity in myotubes independent of oxidative stress', American Journal of Physiology - Cell Physiology, vol. 321, no. 6, pp. C1000-C1009. https://doi.org/10.1152/ajpcell.00116.2021
Kim, HG, Huot, JR, Pin, F, Guo, B, Bonetto, A & Nader, GA 2021, 'Reduced rDNA transcription diminishes skeletal muscle ribosomal capacity and protein synthesis in cancer cachexia', FASEB Journal, vol. 35, no. 2, e21335. https://doi.org/10.1096/fj.202002257R