Guy Edmund Townsend, PhD - Penn State Cancer Institute
Researcher Profile
Guy Edmund Townsend, PhD
Assistant Professor, Department of Biochemistry and Molecular Biology
Research Interests
- Bacteria
- Bacteroides thetaiotaomicron
- Polysaccharides
- Genes
- Proteins
- Nutrients
- Carbohydrates
- Growth
- Mesorhizobium
- Dietary Sugars
- Gastrointestinal Microbiome
- Bacteroides
Recent Publications
2023
Krypotou, E, Townsend, GE, Gao, X, Tachiyama, S, Liu, J, Pokorzynski, ND, Goodman, AL & Groisman, EA 2023, 'Bacteria require phase separation for fitness in the mammalian gut', Science, vol. 379, no. 6637, eabn7229. https://doi.org/10.1126/science.abn7229
Pearce, VH, Groisman, EA & Townsend, GE 2023, 'Dietary sugars silence the master regulator of carbohydrate utilization in human gut Bacteroides species', Gut microbes, vol. 15, no. 1, 2221484. https://doi.org/10.1080/19490976.2023.2221484
Modesto, JL, Pearce, VH & Townsend, GE 2023, 'Harnessing gut microbes for glycan detection and quantification', Nature communications, vol. 14, no. 1, 275. https://doi.org/10.1038/s41467-022-35626-2
2022
Han, W, Peng, BZ, Wang, C, Townsend, GE, Barry, NA, Peske, F, Goodman, AL, Liu, J, Rodnina, MV & Groisman, EA 2023, 'Gut colonization by Bacteroides requires translation by an EF-G paralog lacking GTPase activity', EMBO Journal, vol. 42, no. 2, e112372. https://doi.org/10.15252/embj.2022112372
2020
Townsend, GE, Han, W, Schwalm, ND, Hong, X, Bencivenga-Barry, NA, Goodman, AL & Groisman, EA 2020, 'A master regulator of bacteroides thetaiotaomicron gut colonization controls carbohydrate utilization and an alternative protein synthesis factor', mBio, vol. 11, no. 1, e03221-19. https://doi.org/10.1128/mBio.03221-19
2019
Townsend, GE, Han, W, Schwalm, ND, Raghavan, V, Barry, NA, Goodman, AL & Groisman, EA 2019, 'Dietary sugar silences a colonization factor in a mammalian gut symbiont', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 1, pp. 233-238. https://doi.org/10.1073/pnas.1813780115
Townsend, GE, Han, W, Schwalm, ND, Raghavan, V, Barry, NA, Goodman, AL & Groisman, EA 2019, 'Erratum: Dietary sugar silences a colonization factor in a mammalian gut symbiont (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (233–238) DOI: 10.1073/pnas.1813780115)', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 12, pp. 5831. https://doi.org/10.1073/pnas.1902700116