Researcher Profile

Researcher Profile

Katsuhiko Murakami

Katsuhiko Murakami

Professor, Biochemistry & Molecular Biology
Scientific Program:Mechanisms of Carcinogenesis
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Research Interests

  • DNA-Directed RNA Polymerases
  • DNA
  • Escherichia coli
  • X-Rays
  • Proteins
  • Enzymes
  • Bacterial RNA
  • Holoenzymes
  • Transcriptional Activation
  • Transcription Factors
  • RNA
  • Binding Sites

Recent Publications




Molodtsov, V & Murakami, K 2018, 'Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II' Journal of Biological Chemistry, vol. 293, no. 35, pp. 13616-13625.






Molodtsov, V, Fleming, PR, Eyermann, CJ, Ferguson, AD, Foulk, MA, McKinney, DC, Masse, CE, Buurman, ET & Murakami, K 2015, 'X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein', Journal of Medicinal Chemistry, vol. 58, no. 7, pp. 3156-3171.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)