Researcher Profile
Researcher Profile
Andrea Hobkirk, PhD
Assistant Professor, Department of Psychiatry and Behavioral Health
Assistant Professor, Department of Public Health Sciences
Assistant Professor, Department of Public Health Sciences
Scientific Program:Cancer Control
Research Interests
Dr. Andrea Hobkirk is the principal investigator of the addiction, behavioral neuroscience and social determinants of health research lab area in the Department of Psychiatry. Her lab’s mission is to better understand pathways between the brain and behavior that lead to the development and treatment of addiction.
She is working to uncover how pre-existing differences in stress, reward and executive control systems make some individuals more likely to develop an addiction when they first start using a drug, and how these same systems can be changed with intervention to alleviate addiction.
Although her lab studies many substances of abuse, her current projects are focused on how brain function changes as people develop and recover from nicotine addiction. She is specifically interested in how tobacco product features, like flavors, affect the development of nicotine addiction.
Her research studies collect data from participants through surveys, computer games, functional magnetic resonance imaging and biomarkers such as blood, urine and saliva.
- HIV
- Nicotine
- Brain
- Methamphetamine
- South Africa
- Decision Making
- Cocaine
- Reward
- Tobacco Products
- Depression
- Mindfulness
- Vaping
Recent Publications
2021
Hobkirk, A, Midya, V, Krebs, NM, Allen, SI, Reinhart, L, Sun, D, Stennett, AL & Muscat, JE 2021, 'Characterizing nicotine exposure among a community sample of non-daily smokers in the United States', BMC Public Health, vol. 21, no. 1, 1025. https://doi.org/10.1186/s12889-021-11052-9
Hobkirk, A, Houser, KR, Hoglen, B, Bitzer, ZT, Fendrich, A, Bordner, CR, Foulds, J, Wang, J, Mukherjee, D, Yingst, J, Karunanayaka, P, Goel, R, Richie, JP, Elias, RJ & Yang, QX 2021, 'Evidence from an fMRI study that dessert-flavored e-cigarettes engage taste-related, but not smoking-related, brain circuitry for female daily smokers.', Experimental and clinical psychopharmacology. https://doi.org/10.1037/pha0000488
Hall, SA, Towe, SL, Nadeem, MT, Hobkirk, AL, Hartley, BW, Li, R, Huettel, SA & Meade, CS 2021, 'Hypoactivation in the precuneus and posterior cingulate cortex during ambiguous decision making in individuals with HIV', Journal of neurovirology, vol. 27, no. 3, pp. 463-475. https://doi.org/10.1007/s13365-021-00981-1
Yingst, JM, Bordner, CR, Hobkirk, AL, Hoglen, B, Allen, SI, Krebs, NM, Houser, KR, Livelsberger, C & Foulds, J 2021, 'Response to flavored cartridge/pod-based product ban among adult juul users: “you get nicotine however you can get it”', International journal of environmental research and public health, vol. 18, no. 1, 207, pp. 1-13. https://doi.org/10.3390/ijerph18010207
Yingst, JM, Krebs, NM, Bordner, CR, Hobkirk, AL, Allen, SI & Foulds, J 2021, 'Tobacco use changes and perceived health risks among current tobacco users during the COVID-19 pandemic', International journal of environmental research and public health, vol. 18, no. 4, 1795, pp. 1-11. https://doi.org/10.3390/ijerph18041795
2020
Hobkirk, AL, Bitzer, Z, Goel, R, Sica, CT, Livelsberger, C, Yingst, J, Houser, KR, Rupprecht, S, Trushin, N, Karunanayaka, P, Foulds, J, Richie, JP, Spreen, L, Hoglen, B, Wang, J, Elias, RJ & Yang, QX 2020, 'An Electronic Aerosol Delivery System for Functional Magnetic Resonance Imaging', Substance Abuse: Research and Treatment, vol. 14. https://doi.org/10.1177/1178221820904140
Yingst, J, Foulds, J & Hobkirk, AL 2021, 'Dependence and Use Characteristics of Adult JUUL Electronic Cigarette Users', Substance Use and Misuse, vol. 56, no. 1, pp. 61-66. https://doi.org/10.1080/10826084.2020.1834582
2019
Yingst, JM, Hrabovsky, S, Hobkirk, A, Trushin, N, Richie, JP & Foulds, J 2019, 'Nicotine Absorption Profile Among Regular Users of a Pod-Based Electronic Nicotine Delivery System', JAMA network open, vol. 2, no. 11, pp. e1915494. https://doi.org/10.1001/jamanetworkopen.2019.15494
Yingst, JM, Foulds, J, Veldheer, S, Hrabovsky, S, Trushin, N, Eissenberg, TT, Williams, J, Richie, JP, Nichols, TT, Wilson, SJ & Hobkirk, AL 2019, 'Nicotine absorption during electronic cigarette use among regular users', PloS one, vol. 14, no. 7, e0220300. https://doi.org/10.1371/journal.pone.0220300
Hobkirk, AL, Bell, RP, Utevsky, AV, Huettel, S & Meade, CS 2019, 'Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users', Drug and alcohol dependence, vol. 194, pp. 32-39. https://doi.org/10.1016/j.drugalcdep.2018.09.013
2018
Foulds, J, Hobkirk, A, Wasserman, E, Richie, J, Veldheer, S, Krebs, NM, Reinhart, L & Muscat, J 2018, 'Estimation of compliance with exclusive smoking of very low nicotine content cigarettes using plasma cotinine', Preventive Medicine, vol. 117, pp. 24-29. https://doi.org/10.1016/j.ypmed.2018.04.011
Pacek, LR, Towe, SL, Hobkirk, AL, Nash, D & Goodwin, RD 2018, 'Frequency of cannabis use and medical cannabis use among persons living with HIV in the united states: Findings from a nationally representative sample', AIDS Education and Prevention, vol. 30, no. 2, pp. 169-181. https://doi.org/10.1521/aeap.2018.30.2.169
Hobkirk, AL, Krebs, NM & Muscat, JE 2018, 'Income as a moderator of psychological stress and nicotine dependence among adult smokers', Addictive Behaviors, vol. 84, pp. 215-223. https://doi.org/10.1016/j.addbeh.2018.04.021
Meade, CS, Bell, RP, Towe, SL, Chen, NK, Hobkirk, AL & Huettel, SA 2019, 'Synergistic effects of marijuana abuse and HIV infection on neural activation during a cognitive interference task', Addiction Biology, vol. 24, no. 6, pp. 1235-1244. https://doi.org/10.1111/adb.12678
2017
Hobkirk, A, Nichols, TT, Foulds, J, Yingst, JM, Veldheer, S, Hrabovsky, S, Richie, J, Eissenberg, T & Wilson, S 2018, 'Changes in resting state functional brain connectivity and withdrawal symptoms are associated with acute electronic cigarette use', Brain Research Bulletin, vol. 138, pp. 56-63. https://doi.org/10.1016/j.brainresbull.2017.05.010
Meade, CS, Addicott, M, Hobkirk, AL, Towe, SL, Chen, NK, Sridharan, S & Huettel, SA 2018, 'Cocaine and HIV are independently associated with neural activation in response to gain and loss valuation during economic risky choice', Addiction Biology, vol. 23, no. 2, pp. 796-809. https://doi.org/10.1111/adb.12529
Meade, CS, Hobkirk, AL, Towe, SL, Chen, NK, Bell, RP & Huettel, SA 2017, 'Cocaine dependence modulates the effect of HIV infection on brain activation during intertemporal decision making', Drug and alcohol dependence, vol. 178, pp. 443-451. https://doi.org/10.1016/j.drugalcdep.2017.05.043
Hobkirk, AL, Towe, SL, Patel, P & Meade, CS 2017, 'Food Insecurity Is Associated with Cognitive Deficits Among HIV-Positive, But Not HIV-Negative, Individuals in a United States Sample', AIDS and Behavior, vol. 21, no. 3, pp. 783-791. https://doi.org/10.1007/s10461-016-1514-7
Watt, MH, Guidera, KE, Hobkirk, AL, Skinner, D & Meade, CS 2017, 'Intimate partner violence among men and women who use methamphetamine: A mixed-methods study in South Africa', Drug and Alcohol Review, vol. 36, no. 1, pp. 97-106. https://doi.org/10.1111/dar.12420
Berg, MK, Hobkirk, AL, Meade, CS & Joska, JA 2017, 'The Role of Substance Use Coping in the Relation between Childhood Sexual Abuse and Depression among Methamphetamine Users in South Africa', Psychological Trauma: Theory, Research, Practice, and Policy, vol. 9, no. 4, pp. 493-499. https://doi.org/10.1037/tra0000207