Researcher Profile

Researcher Profile

Michael Glantz, MD, PhD

Michael Glantz, MD, PhD

Professor, Department of Neurosurgery
Professor, Department of Medicine
Scientific Program:Next-Generation Therapies
Disease Teams:
Brain and Central Nervous System Cancer

Research Interests

  • Neoplasms
  • Therapeutics
  • Cerebrospinal Fluid
  • Brain Neoplasms
  • Drug Therapy
  • Glioma
  • Radiotherapy
  • Survival
  • Meningitis
  • Glioblastoma
  • Brain
  • Neoplasm Metastasis

Clinical Trials

Maintenance Obinutuzumab for Primary Central Nervous System Lymphoma Complete Responders
Molecular Genetic, Host-Derived and Clinical Determinants of Long-Term Survival in Glioblastoma
A biospecimen collection study to evaluate the pharmacokinetic,pharmacodynamic, and resistance profile to trametinib and dabrafenib in BRAF-V600E mutated recurrent gliomas
3D-PREDICT Registry: 3D Prediction of patient-specific Response using ex vivo Interrogation of live cells from tumors
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Enzastaurin Added to Temozolomide During and Following Radiation Therapy in Newly Diagnosed Glioblastoma Patients Who Possess the Novel Genomic Biomarker DGM1
Risk Factors for CIPN Following an Oxaliplatin-Containing Chemotherapy Regimen in Colorectal Cancer Patients

Recent Publications


Hallan, DR, Nguyen, AM, Liang, M, McNutt, S, Goss, M, Bell, E, Natarajan, S, Nichol, A, Messner, C, Bracken, E & Glantz, M 2022, 'Charting the course from abstract to published article', Journal of neurosurgery, vol. 136, no. 6, pp. 1773-1780.


Halper-Stromberg, E, McCall, CM, Haley, LM, Lin, MT, Vogt, S, Gocke, CD, Eshleman, JR, Stevens, W, Martinson, NA, Epeldegui, M, Holdhoff, M, Bettegowda, C, Glantz, MJ, Ambinder, RF & Xian, RR 2021, 'CloneRetriever: An Automated Algorithm to Identify Clonal B and T Cell Gene Rearrangements by Next-Generation Sequencing for the Diagnosis of Lymphoid Malignancies', Clinical chemistry, vol. 67, no. 11, pp. 1524-1533.
Taslimi, S, Brar, K, Ellenbogen, Y, Deng, J, Hou, W, Moraes, FY, Glantz, M, Zacharia, BE, Tan, A, Ahluwalia, MS, Khasraw, M, Zadeh, G & Mansouri, A 2021, 'Comparative Efficacy of Systemic Agents for Brain Metastases From Non-Small-Cell Lung Cancer With an EGFR Mutation/ALK Rearrangement: A Systematic Review and Network Meta-Analysis', Frontiers in Oncology, vol. 11, 739765.
Brar, K, Taslimi, S, Ellenbogen, Y, Deng, J, Hou, W, Moraes, FY, Glantz, M, Zacharia, BE, Tan, A, Ahluwalia, MS, Khasraw, M, Zadeh, G & Mansouri, A 2022, 'Comparative Efficacy of Treatments for Brain Metastases from Non–Small Cell Lung Cancer without an EGFR-Mutation/ALK-Rearrangement: A Systematic Review and Network Meta-Analysis', World neurosurgery, vol. 158, pp. e87-e102.
Schreck, KC, Morin, A, Zhao, G, Allen, AN, Flannery, P, Glantz, M, Green, AL, Jones, C, Jones, KL, Kilburn, LB, Nazemi, KJ, Samuel, D, Sanford, B, Solomon, DA, Wang, J, Pratilas, CA, Nicolaides, T & Levy, JMM 2021, 'Deconvoluting mechanisms of acquired resistance to RAF inhibitors in BRAFV600E-Mutant Human Glioma', Clinical Cancer Research, vol. 27, no. 22, pp. 6197-6208.


Bernstein, A, Mrowczynski, OD, Greene, A, Ryan, S, Chung, C, Zacharia, BE & Glantz, M 2020, 'Dual BRAF/MEK therapy in BRAF V600E-mutated primary brain tumors: A case series showing dramatic clinical and radiographic responses and a reduction in cutaneous toxicity', Journal of neurosurgery, vol. 133, no. 6, pp. 1704-1709.
Yee, PP, Wei, Y, Kim, SY, Lu, T, Chih, SY, Lawson, C, Tang, M, Liu, Z, Anderson, B, Thamburaj, K, Young, MM, Aregawi, DG, Glantz, MJ, Zacharia, BE, Specht, CS, Wang, HG & Li, W 2020, 'Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression', Nature communications, vol. 11, no. 1, 5424.
Glantz, M & Brandmeir, N 2020, 'When can we be positive about p values?', Journal of neurosurgery, vol. 132, no. 2, pp. 656-661.


Wen, PY, Reardon, DA, Armstrong, TS, Phuphanich, S, Aiken, RD, Landolfi, JC, Curry, WT, Zhu, JJ, Glantz, M, Peereboom, DM, Markert, JM, LaRocca, R, O'Rourke, DM, Fink, K, Kim, L, Gruber, M, Lesser, GJ, Pan, E, Kesari, S, Muzikansky, A, Pinilla, C, Santos, RG & Yu, JS 2019, 'A randomized double-blind placebo-controlled phase II trial of dendritic cell vaccine ICT-107 in newly diagnosed patients with glioblastoma', Clinical Cancer Research, vol. 25, no. 19, pp. 5799-5807.
Boire, A, Brandsma, D, Brastianos, PK, Le Rhun, E, Ahluwalia, M, Junck, L, Glantz, M, Groves, MD, Lee, EQ, Lin, N, Raizer, J, RudĂ , R, Weller, M, Van Den Bent, MJ, Vogelbaum, MA, Chang, S, Wen, PY & Soffietti, R 2019, 'Liquid biopsy in central nervous system metastases: A RANO review and proposals for clinical applications', Neuro-oncology, vol. 21, no. 5, pp. 571-583.
Brown, TJ, Bota, DA, Van Den Bent, MJ, Brown, PD, Maher, E, Aregawi, D, Liau, LM, Buckner, JC, Weller, M, Berger, MS & Glantz, M 2019, 'Management of low-grade glioma: A systematic review and meta-Analysis', Neuro-Oncology Practice, vol. 6, no. 4, npy034, pp. 249-258.


Sieg, EP, Schlauderaff, AC, Payne, RA, Glantz, MJ & Simon, SD 2018, 'Impact of an External Ventricular Drain Placement and Handling Protocol on Infection Rates: A Meta-Analysis and Single Institution Experience', World neurosurgery, vol. 115, pp. e53-e58.
Brennan, M, Brown, T, Koller, K, Vasekar, M, Cygan, P, Ali, A, Sivik, J & Glantz, M 2018, 'Target wise and pound foolish: A simple technique to evaluate the trade-off between clinical benefit and economic burden of monoclonal antibodies', Journal of Cancer Policy, vol. 18, pp. 11-19.
Zoccoli, C, Li, CF, Black, D, Smith, DB, Sheehan, J, Harbaugh, RE & Glantz, M 2019, 'The Honest Palm Sign: Detecting Incomplete Effort on Physical Examination', World neurosurgery, vol. 122, pp. e1354-e1358.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)