Thomas Spratt, PhD - Penn State Cancer Institute
Researcher Profile
Thomas Spratt, PhD
Professor, Department of Molecular and Precision Medicine
Penn State Center for Research on Tobacco and Health
Penn State Center for Research on Tobacco and Health
Scientific Program:Mechanisms of Carcinogenesis
Recent Publications
2025
Rebok, A, Torres, MC, Ambrose, JR & Spratt, TE 2025, 'Catalytic-Dependent Role of DNA Polymerase κ in Nucleotide Excision Repair', Chemical research in toxicology, vol. 38, no. 6, pp. 1103-1112. https://doi.org/10.1021/acs.chemrestox.5c00085
Rebok, AM & Spratt, TE 2025, Repair Mechanisms and Initiation in Carcinogenesis. in Comprehensive Toxicology. Elsevier, pp. Vol13:45-Vol15:81. https://doi.org/10.1016/B978-0-323-95488-4.00089-9
Dhoonmoon, A, Ambrose, JR, Garg, S, Lascarez-Espana, C, Rebok, A, Spratt, TE, Moldovan, GL & Nicolae, CM 2025, 'Translesion-synthesis-mediated bypass of DNA lesions occurs predominantly behind replication forks restarted by PrimPol', Cell Reports, vol. 44, no. 3, 115360. https://doi.org/10.1016/j.celrep.2025.115360
2024
Torres, MC, Rebok, A, Sun, D & Spratt, TE 2024, 'Activity of DNA polymerase κ across the genome in human fibroblasts', Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 28, e2403130121. https://doi.org/10.1073/pnas.2403130121
2023
Spratt, TE 2023, 'Stephen S. Hecht Has Played a Major Role in Investigating Tobacco Carcinogenesis', Chemical research in toxicology, vol. 36, no. 4, pp. 563-564. https://doi.org/10.1021/acs.chemrestox.3c00082