Researcher Profile

Researcher Profile

Sang Lee, MS, PhD

Sang Lee, MS, PhD

Associate Professor, Department of Neurosurgery
Penn State Neuroscience Institute
Scientific Program:Next-Generation Therapies
syl3@psu.edu

Research Interests

  • Genes
  • Iron
  • Neoplasms
  • Alzheimer Disease
  • Mutation
  • Neuroblastoma
  • Cell Line
  • Hemochromatosis
  • Oxidative Stress
  • Phosphorylation
  • Amyotrophic Lateral Sclerosis
  • Temozolomide

Recent Publications

2019

Howarth, A, Simms, C, Kerai, N, Allen, O, Mihajluk, K, Madureira, PA, Sokratous, G, Cragg, S, Lee, SY, Morley, AD, Keyoumars, A, Cox, PA, Pilkington, GJ & Hill, R 2019, 'DIVERSet JAG Compounds Inhibit Topoisomerase II and Are Effective Against Adult and Pediatric High-Grade Gliomas', Translational Oncology, vol. 12, no. 10, pp. 1375-1385. https://doi.org/10.1016/j.tranon.2019.07.007
Payne, R, Mrowczynski, OD, Slagle-Webb, B, Bourcier, A, Mau, C, Aregawi, D, Madhankumar, AB, Lee, SY, Harbaugh, K, Connor, J & Rizk, EB 2019, 'MLN8237 treatment in an orthoxenograft murine model for malignant peripheral nerve sheath tumors', Journal of neurosurgery, vol. 130, no. 2, pp. 465-475. https://doi.org/10.3171/2017.8.JNS17765
Mairuae, N, Connor, JR, Buranrat, B & Lee, SY 2019, 'Oroxylum indicum (L.) extract protects human neuroblastoma SH-SY5Y cells against ß-amyloid-induced cell injury', Molecular medicine reports, vol. 20, no. 2, pp. 1933-1942. https://doi.org/10.3892/mmr.2019.10411

2018

Lee, S 2018, 'Current Knowledge for the Western Blot Normalization', Journal of Medical Oncology and Therapeutics, vol. 3, no. 1, pp. 3-9.
Kwak, HS, An, H, Alam, MB, Choi, WS, Lee, S & Lee, SH 2018, 'Inhibition of migration and invasion in melanoma cells by β-escin via the ERK/NF-κB signaling pathway', Biological and Pharmaceutical Bulletin, vol. 41, no. 10, pp. 1606-1610. https://doi.org/10.1248/bpb.b18-00251

2017

Lee, SY, Zhu, J, Salzberg, AC, Zhang, B, Liu, DJ, Muscat, JE, Langan, ST & Connor, JR 2017, 'Analysis of single nucleotide variants of HFE gene and association to survival in the Cancer Genome Atlas GBM data', PloS one, vol. 12, no. 3, e0174778. https://doi.org/10.1371/journal.pone.0174778
Ramisetti, SR, Pandey, MK, Lee, S, Karelia, D, Narayan, S, Amin, S & Sharma, A 2018, 'Design and synthesis of novel thiobarbituric acid derivatives targeting both wild-type and BRAF-mutated melanoma cells', European Journal of Medicinal Chemistry, vol. 143, pp. 1919-1930. https://doi.org/10.1016/j.ejmech.2017.11.006
Mrowczynski, OD, Madhankumar, AB, Slagle-Webb, B, Lee, SY, Zacharia, BE & Connor, JR 2017, 'HFE genotype affects exosome phenotype in cancer', Biochimica et Biophysica Acta - General Subjects, vol. 1861, no. 8, pp. 1921-1928. https://doi.org/10.1016/j.bbagen.2017.05.014

2016

Lee, S 2016, 'Temozolomide resistance in glioblastoma multiforme', Genes and Diseases, vol. 3, no. 3, pp. 198-210. https://doi.org/10.1016/j.gendis.2016.04.007

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)