Shantu Amin, PhD
Dr. Shantu Amin is director of the Organic Synthesis Core of Penn State Cancer Institute. His laboratory is nationally recognized for developing synthetic strategies for novel small drug-like molecules for cancer prevention and therapy.
The major focus of Dr. Amin’s research is the synthesis of anti-cancer agents, elucidating their efficacy and investigating their drug metabolism. He has also been involved in structure-activity studies with mutagenic and carcinogenic compounds and using this knowledge to develop appropriate chemopreventive agents.
These studies have resulted in the development of several chemopreventive/ chemotherapeutic agents and an understanding of their mechanisms of action.
- Epoxy Compounds
- DNA Adducts
- Polycyclic Aromatic Hydrocarbons