Researcher Profile

Researcher Profile

Raghu Sinha, MS, PhD

Raghu Sinha, MS, PhD

Associate Professor, Department of Biochemistry and Molecular Biology
Scientific Program:Cancer Control
rus15@psu.edu

Research Interests

  • Selenium
  • Proteins
  • Neoplasms
  • Breast Neoplasms
  • Biomarkers
  • Prostatic Neoplasms
  • Growth
  • In Vitro Techniques
  • selenomethylselenocysteine
  • Epithelial Cells
  • Chemoprevention
  • Organoselenium Compounds

Recent Publications

2022

Ma, L, Xiu, G, Muscat, J, Sinha, R, Sun, D & Xiu, G 2022, 'Comparative proteomic analysis of exhaled breath condensate between lung adenocarcinoma and CT-detected benign pulmonary nodule patients', Cancer Biomarkers, vol. 34, no. 2, pp. 163-174. https://doi.org/10.3233/CBM-203269
Wooten, DJ, Sinha, I & Sinha, R 2022, 'Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine', Biomedicines, vol. 10, no. 1, 149. https://doi.org/10.3390/biomedicines10010149

2021

Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, R & Richie, JP 2022, 'Association of dietary sulfur amino acid intake with mortality from diabetes and other causes', European Journal of Nutrition, vol. 61, no. 1, pp. 289-298. https://doi.org/10.1007/s00394-021-02641-w
Sinha, I, Modesto, J, Krebs, NM, Stanley, AE, Walter, VA, Richie, JP, Muscat, JE & Sinha, R 2021, 'Changes in salivary proteome before and after cigarette smoking in smokers compared to sham smoking in nonsmokers: A pilot study', Tobacco Induced Diseases, vol. 19, 138336. https://doi.org/10.18332/TID/138336
Turanli, B, Yildirim, E, Gulfidan, G, Arga, KY & Sinha, R 2021, 'Current state of “omics” biomarkers in pancreatic cancer', Journal of Personalized Medicine, vol. 11, no. 2, 127, pp. 1-24. https://doi.org/10.3390/jpm11020127
Gulfidan, G, Beklen, H, Sinha, I, Kucukalp, F, Caloglu, B, Esen, I, Turanli, B, Ayyildiz, DI, Arga, KY & Sinha, R 2021, 'Differential Protein Interactome in Esophageal Squamous Cell Carcinoma Offers Novel Systems Biomarker Candidates with High Diagnostic and Prognostic Performance', OMICS A Journal of Integrative Biology, vol. 25, no. 8, pp. 495-512. https://doi.org/10.1089/omi.2021.0085
Caliskan, A, Gulfidan, G, Sinha, R & Arga, KY 2021, 'Differential interactome proposes subtype-specific biomarkers and potential therapeutics in renal cell carcinomas', Journal of Clinical Medicine, vol. 10, no. 4, 158, pp. 1-12. https://doi.org/10.3390/jpm11020158
Ma, L, Muscat, JE, Sinha, R, Sun, D & Xiu, G 2021, 'Proteomics of exhaled breath condensate in lung cancer and controls using data-independent acquisition (DIA): A pilot study', Journal of Breath Research, vol. 15, no. 2, 026002. https://doi.org/10.1088/1752-7163/abd07e
Arga, KY & Sinha, R 2021, 'Recent developments in cancer systems biology: Lessons learned and future directions', Journal of Personalized Medicine, vol. 11, no. 4, 271. https://doi.org/10.3390/jpm11040271

2020

Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, RM & Richie, JP 2020, 'Association of sulfur amino acid consumption with cardiometabolic risk factors: Cross-sectional findings from NHANES III', EClinicalMedicine, vol. 19, 100248. https://doi.org/10.1016/j.eclinm.2019.100248
Gulfidan, G, Turanli, B, Beklen, H, Sinha, R & Arga, KY 2020, 'Pan-cancer mapping of differential protein-protein interactions', Scientific reports, vol. 10, no. 1, 3272. https://doi.org/10.1038/s41598-020-60127-x

2019

Komninou, D, Malloy, VL, Zimmerman, JA, Sinha, R & Richie, JP 2020, 'Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats', GeroScience, vol. 42, no. 1, pp. 287-297. https://doi.org/10.1007/s11357-019-00129-4
Turanli, B, Karagoz, K, Bidkhori, G, Sinha, R, Gatza, ML, Uhlen, M, Mardinoglu, A & Arga, KY 2019, 'Multi-omic data interpretation to repurpose subtype specific drug candidates for breast cancer', Frontiers in Genetics, vol. 10, no. MAY, 420. https://doi.org/10.3389/fgene.2019.00420
Soni, C, Sinha, I, Fasnacht, MJ, Olsen, NJ, Rahman, ZSM & Sinha, R 2019, 'Selenium supplementation suppresses immunological and serological features of lupus in B6.Sle1b mice', Autoimmunity, vol. 52, no. 2, pp. 57-68. https://doi.org/10.1080/08916934.2019.1603297

2018

Turanli, B, Karagoz, K, Gulfidan, G, Sinha, R, Mardinoglu, A & Arga, KY 2018, 'A network-based cancer drug discovery: From integrated multi-omics approaches to precision medicine', Current Pharmaceutical Design, vol. 24, no. 32, pp. 3778-3790. https://doi.org/10.2174/1381612824666181106095959
Dong, Z, Sinha, R & Richie, JP 2018, 'Disease prevention and delayed aging by dietary sulfur amino acid restriction: Translational implications', Annals of the New York Academy of Sciences, vol. 1418, no. 1, pp. 44-55. https://doi.org/10.1111/nyas.13584
Sinha, R, Sinha, I, Calcagnotto, A, Trushin, N, Haley, JS, Schell, TD & Richie, JP 2018, 'Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function', European Journal of Clinical Nutrition, vol. 72, no. 1, pp. 105-111. https://doi.org/10.1038/ejcn.2017.132

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