Raghu Sinha, MS, PhD - Penn State Cancer Institute
Researcher Profile
Raghu Sinha, MS, PhD
Associate Professor, Department of Biochemistry and Molecular Biology
Scientific Program:Cancer Control
Research Interests
- Proteins
- Selenium
- Neoplasms
- Breast Neoplasms
- In Vitro Techniques
- Biomarkers
- Prostatic Neoplasms
- Growth
- Epithelial Cells
- selenomethylselenocysteine
- Chemoprevention
- Organoselenium Compounds
Recent Publications
2024
Kori, M, Demirtas, TY, Comertpay, B, Arga, KY, Sinha, R & Gov, E 2024, 'A 19-Gene Signature of Serous Ovarian Cancer Identified by Machine Learning and Systems Biology: Prospects for Diagnostics and Personalized Medicine', OMICS A Journal of Integrative Biology, vol. 28, no. 2, pp. 90-101. https://doi.org/10.1089/omi.2023.0273
2023
Richie, JP, Sinha, R, Dong, Z, Nichenametla, SN, Ables, GP, Ciccarella, A, Sinha, I, Calcagnotto, AM, Chinchilli, VM, Reinhart, L & Orentreich, D 2023, 'Dietary Methionine and Total Sulfur Amino Acid Restriction in Healthy Adults', Journal of Nutrition, Health and Aging, vol. 27, no. 2, pp. 111-123. https://doi.org/10.1007/s12603-023-1883-3
Sinha, I, Fogle, RL, Gulfidan, G, Stanley, AE, Walter, V, Hollenbeak, CS, Arga, KY & Sinha, R 2023, 'Potential Early Markers for Breast Cancer: A Proteomic Approach Comparing Saliva and Serum Samples in a Pilot Study', International journal of molecular sciences, vol. 24, no. 4, 4164. https://doi.org/10.3390/ijms24044164
Sinha, I, Zhu, J & Sinha, R 2023, 'Selective Impact of Selenium Compounds on Two Cytokine Storm Players', Journal of Personalized Medicine, vol. 13, no. 10, 1455. https://doi.org/10.3390/jpm13101455
2022
Kori, M, Ozdemir, GE, Arga, KY & Sinha, R 2022, 'A Pan-Cancer Atlas of Differentially Interacting Hallmarks of Cancer Proteins', Journal of Personalized Medicine, vol. 12, no. 11, 1919. https://doi.org/10.3390/jpm12111919
Ma, L, Xiu, G, Muscat, J, Sinha, R, Sun, D & Xiu, G 2022, 'Comparative proteomic analysis of exhaled breath condensate between lung adenocarcinoma and CT-detected benign pulmonary nodule patients', Cancer Biomarkers, vol. 34, no. 2, pp. 163-174. https://doi.org/10.3233/CBM-203269
Sinha, I, Goel, R, Bitzer, ZT, Trushin, N, Liao, J & Sinha, R 2022, 'Evaluating electronic cigarette cytotoxicity and inflammatory responses in vitro', Tobacco Induced Diseases, vol. 20, no. 5, 45. https://doi.org/10.18332/tid/147200
Wooten, DJ, Sinha, I & Sinha, R 2022, 'Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine', Biomedicines, vol. 10, no. 1, 149. https://doi.org/10.3390/biomedicines10010149
2021
Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, R & Richie, JP 2022, 'Association of dietary sulfur amino acid intake with mortality from diabetes and other causes', European Journal of Nutrition, vol. 61, no. 1, pp. 289-298. https://doi.org/10.1007/s00394-021-02641-w
Sinha, I, Modesto, J, Krebs, NM, Stanley, AE, Walter, VA, Richie, JP, Muscat, JE & Sinha, R 2021, 'Changes in salivary proteome before and after cigarette smoking in smokers compared to sham smoking in nonsmokers: A pilot study', Tobacco Induced Diseases, vol. 19, 138336. https://doi.org/10.18332/TID/138336
Turanli, B, Yildirim, E, Gulfidan, G, Arga, KY & Sinha, R 2021, 'Current state of “omics” biomarkers in pancreatic cancer', Journal of Personalized Medicine, vol. 11, no. 2, 127, pp. 1-24. https://doi.org/10.3390/jpm11020127
Gulfidan, G, Beklen, H, Sinha, I, Kucukalp, F, Caloglu, B, Esen, I, Turanli, B, Ayyildiz, DI, Arga, KY & Sinha, R 2021, 'Differential Protein Interactome in Esophageal Squamous Cell Carcinoma Offers Novel Systems Biomarker Candidates with High Diagnostic and Prognostic Performance', OMICS A Journal of Integrative Biology, vol. 25, no. 8, pp. 495-512. https://doi.org/10.1089/omi.2021.0085
Caliskan, A, Gulfidan, G, Sinha, R & Arga, KY 2021, 'Differential interactome proposes subtype-specific biomarkers and potential therapeutics in renal cell carcinomas', Journal of Clinical Medicine, vol. 11, no. 2, 158, pp. 1-12. https://doi.org/10.3390/jpm11020158
Ma, L, Muscat, JE, Sinha, R, Sun, D & Xiu, G 2021, 'Proteomics of exhaled breath condensate in lung cancer and controls using data-independent acquisition (DIA): A pilot study', Journal of Breath Research, vol. 15, no. 2, 026002. https://doi.org/10.1088/1752-7163/abd07e
Arga, KY & Sinha, R 2021, 'Recent developments in cancer systems biology: Lessons learned and future directions', Journal of Personalized Medicine, vol. 11, no. 4, 271. https://doi.org/10.3390/jpm11040271
2020
Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, RM & Richie, JP 2020, 'Association of sulfur amino acid consumption with cardiometabolic risk factors: Cross-sectional findings from NHANES III', EClinicalMedicine, vol. 19, 100248. https://doi.org/10.1016/j.eclinm.2019.100248
Gulfidan, G, Turanli, B, Beklen, H, Sinha, R & Arga, KY 2020, 'Pan-cancer mapping of differential protein-protein interactions', Scientific reports, vol. 10, no. 1, 3272. https://doi.org/10.1038/s41598-020-60127-x