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Researcher Profile

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Raghu Sinha, MS, PhD

Raghu Sinha, MS, PhD

Associate Professor, Department of Biochemistry and Molecular Biology
Penn State Center for Research on Tobacco and Health
Scientific Program:Cancer Control

Research Interests

  • Proteins
  • Selenium
  • Neoplasms
  • Breast Neoplasms
  • In Vitro Techniques
  • Biomarkers
  • Prostatic Neoplasms
  • Growth
  • Epithelial Cells
  • selenomethylselenocysteine
  • Chemoprevention
  • Organoselenium Compounds

Recent Publications


Kori, M, Demirtas, TY, Comertpay, B, Arga, KY, Sinha, R & Gov, E 2024, 'A 19-Gene Signature of Serous Ovarian Cancer Identified by Machine Learning and Systems Biology: Prospects for Diagnostics and Personalized Medicine', OMICS A Journal of Integrative Biology, vol. 28, no. 2, pp. 90-101.


Richie, JP, Sinha, R, Dong, Z, Nichenametla, SN, Ables, GP, Ciccarella, A, Sinha, I, Calcagnotto, AM, Chinchilli, VM, Reinhart, L & Orentreich, D 2023, 'Dietary Methionine and Total Sulfur Amino Acid Restriction in Healthy Adults', Journal of Nutrition, Health and Aging, vol. 27, no. 2, pp. 111-123.
Sinha, I, Fogle, RL, Gulfidan, G, Stanley, AE, Walter, V, Hollenbeak, CS, Arga, KY & Sinha, R 2023, 'Potential Early Markers for Breast Cancer: A Proteomic Approach Comparing Saliva and Serum Samples in a Pilot Study', International journal of molecular sciences, vol. 24, no. 4, 4164.
Sinha, I, Zhu, J & Sinha, R 2023, 'Selective Impact of Selenium Compounds on Two Cytokine Storm Players', Journal of Personalized Medicine, vol. 13, no. 10, 1455.


Kori, M, Ozdemir, GE, Arga, KY & Sinha, R 2022, 'A Pan-Cancer Atlas of Differentially Interacting Hallmarks of Cancer Proteins', Journal of Personalized Medicine, vol. 12, no. 11, 1919.
Ma, L, Xiu, G, Muscat, J, Sinha, R, Sun, D & Xiu, G 2022, 'Comparative proteomic analysis of exhaled breath condensate between lung adenocarcinoma and CT-detected benign pulmonary nodule patients', Cancer Biomarkers, vol. 34, no. 2, pp. 163-174.
Sinha, I, Goel, R, Bitzer, ZT, Trushin, N, Liao, J & Sinha, R 2022, 'Evaluating electronic cigarette cytotoxicity and inflammatory responses in vitro', Tobacco Induced Diseases, vol. 20, no. 5, 45.
Wooten, DJ, Sinha, I & Sinha, R 2022, 'Selenium Induces Pancreatic Cancer Cell Death Alone and in Combination with Gemcitabine', Biomedicines, vol. 10, no. 1, 149.


Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, R & Richie, JP 2022, 'Association of dietary sulfur amino acid intake with mortality from diabetes and other causes', European Journal of Nutrition, vol. 61, no. 1, pp. 289-298.
Sinha, I, Modesto, J, Krebs, NM, Stanley, AE, Walter, VA, Richie, JP, Muscat, JE & Sinha, R 2021, 'Changes in salivary proteome before and after cigarette smoking in smokers compared to sham smoking in nonsmokers: A pilot study', Tobacco Induced Diseases, vol. 19, 138336.
Turanli, B, Yildirim, E, Gulfidan, G, Arga, KY & Sinha, R 2021, 'Current state of “omics” biomarkers in pancreatic cancer', Journal of Personalized Medicine, vol. 11, no. 2, 127, pp. 1-24.
Gulfidan, G, Beklen, H, Sinha, I, Kucukalp, F, Caloglu, B, Esen, I, Turanli, B, Ayyildiz, DI, Arga, KY & Sinha, R 2021, 'Differential Protein Interactome in Esophageal Squamous Cell Carcinoma Offers Novel Systems Biomarker Candidates with High Diagnostic and Prognostic Performance', OMICS A Journal of Integrative Biology, vol. 25, no. 8, pp. 495-512.
Caliskan, A, Gulfidan, G, Sinha, R & Arga, KY 2021, 'Differential interactome proposes subtype-specific biomarkers and potential therapeutics in renal cell carcinomas', Journal of Clinical Medicine, vol. 11, no. 2, 158, pp. 1-12.
Ma, L, Muscat, JE, Sinha, R, Sun, D & Xiu, G 2021, 'Proteomics of exhaled breath condensate in lung cancer and controls using data-independent acquisition (DIA): A pilot study', Journal of Breath Research, vol. 15, no. 2, 026002.
Arga, KY & Sinha, R 2021, 'Recent developments in cancer systems biology: Lessons learned and future directions', Journal of Personalized Medicine, vol. 11, no. 4, 271.


Dong, Z, Gao, X, Chinchilli, VM, Sinha, R, Muscat, J, Winkels, RM & Richie, JP 2020, 'Association of sulfur amino acid consumption with cardiometabolic risk factors: Cross-sectional findings from NHANES III', EClinicalMedicine, vol. 19, 100248.
Gulfidan, G, Turanli, B, Beklen, H, Sinha, R & Arga, KY 2020, 'Pan-cancer mapping of differential protein-protein interactions', Scientific reports, vol. 10, no. 1, 3272.