Researcher Profile

Researcher Profile

Rebecca Bascom, MD, MPH

Rebecca Bascom, MD, MPH

Professor, Department of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine
Professor, Department of Public Health Sciences
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Research Interests

Dr. Rebecca Bascom has been part of the faculty at Penn State College of Medicine since 1997. Her patient-centered clinical research includes:

  • Ehlers-Danlos syndromes (EDS): Dr. Bascom is coinvestigator on "Educating Primary Care Doctors to Help Patients with Rare Diseases" and serves as part of the monthly EDS STRETCH project clinician research series through Penn State Project ECHO.
  • Interstitial lung disease (ILD): Dr. Bascom is director of Penn State Health Milton S. Hershey Medical Center’s Pulmonary Fibrosis Foundation Care Center, anchoring central Pennsylvania ILD care and research. 

Her electronic health record-related research includes:

  • Pulmonary disease: Dr. Bascom is co-principal investigator of the Patient-Centered Outcomes Research Institute (PCORI)-funded Pulmonary CRG, associated with the COPD Foundation Patient-Powered Research Network. This group helps to incubate junior faculty projects in bronchiectasis, sarcoidosis, sickle cell disease, sleep apnea and the use of natural language processing to classify smoking status. 
  • PaTH Network: Dr. Bascom is coinvestigator on "A PaTH Towards a Learning Health System in the Mid-Atlantic Region – Health System Leaders Demonstration Project." She is also the clinical lead for the PaTH Network's idiopathic pulmonary fibrosis cohort study.

Dr. Bascom's occupational and environmental health clinical research includes work on the interaction between allergic and non-allergic respiratory disease as well as epidemiologic studies of inhaled toxicants.

She participates or has participated in many clinical trials, including the National Institutes of Health's Pulmonary Trials Cooperative; Network Management Core (NEMO); INSIGHT (COPD); and CLEANup IPF. She has also done pharmaceutical work with Boehringer Ingelheim, MediciNova, MedImmune, InterMune, Genentech, Nitto-Denko and Galapagos.

Dr. Bascom also enjoys collaboration with basic science investigators on topics such as inhalation toxicology, toxicant dosimetry, markers and mechanisms of inhaled toxicant susceptibility, modified-risk tobacco broducts and bronchoscopy multimodality image guidance technology.

Funding for her work has come from NIH, PCORI, Pulmonary Fibrosis Foundation, COPD Foundation, Penn State Clinical and Translational Science Institute, Penn State College of Medicine's Grace Woodward Grant, University of Michigan, Pennsylvania Department of Health and pharmaceutical companies. 

Dr. Bascom presents at regional health systems, national and international conferences. She is also a frequent speaker for departmental and divisional Grand Rounds at the College of Medicine and serves on the internal review committee and internal advisory board for Penn State Institute for Personalized Medicine.

  • Nose
  • Lung
  • Smoke
  • Bronchoscopy
  • Tobacco
  • Antigens
  • Asthma
  • Inhalation
  • Tobacco Products
  • Thorax
  • Air
  • Health

Clinical Trials

Repository of Lung Cancer Diagnostic Procedure Images
Piloting a Virtual Navigation (VN) System for Bronchoscopic Tissue Sampling

Recent Publications


Miller, AJ, Schubart, JR, Sheehan, T, Bascom, R & Francomano, CA 2020, 'Arterial elasticity in ehlers-danlos syndromes', Genes, vol. 11, no. 1, 55.
Chang, Q, Bascom, R, Toth, J, Ahmad, D & Higgins, WE 2020, Autofluorescence Bronchoscopy Video Analysis for Lesion Frame Detection. in 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society: Enabling Innovative Technologies for Global Healthcare, EMBC 2020., 9176007, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2020-July, Institute of Electrical and Electronics Engineers Inc., pp. 1556-1559, 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC 2020, Montreal, Canada, 7/20/20.
Claxton, BB, Dimmock, AEF, Jain, R, Drummond, MB & Bascom, R 2020, 'Castleman flare or COPD exacerbation— can biomarkers override availability bias?', Respiratory Medicine Case Reports, vol. 30, 101099.
Du, P, Bascom, R, Fan, T, Sinharoy, A, Yingst, J, Mondal, P & Foulds, J 2020, 'Changes in flavor preference in a cohort of long-term electronic cigarette users', Annals of the American Thoracic Society, vol. 17, no. 5, pp. 573-581.
Higgins, WE, Cheirsilp, R, Kuhlengel, T, Allen, TW, Mahraj, R & Bascom, R 2020, 'Computer-Based 3D PET/CT Thoracic ROI Definition and Visualization', American Journal of Respiratory and Critical Care Medicine. <>
Wells, AU, Flaherty, KR, Brown, KK, Inoue, Y, Devaraj, A, Richeldi, L, Moua, T, Crestani, B, Wuyts, WA, Stowasser, S, Quaresma, M, Goeldner, RG, Schlenker-Herceg, R, Kolb, M, Abe, S, Aburto, M, Acosta, O, Andrews, C, Antin-Ozerkis, D, Arce, G, Arias, M, Avdeev, S, Barczyk, A, Bascom, R, Bazdyrev, E, Beirne, P, Belloli, E, Bergna, MA, Bergot, E, Bhatt, N, Blaas, S, Bondue, B, Bonella, F, Britt, E, Buch, K, Burk, J, Cai, H, Cantin, A, Castillo Villegas, DM, Cazaux, A, Cerri, S, Chaaban, S, Chaudhuri, N, Cottin, V, Crestani, B, Criner, G, Dahlqvist, C, Danoff, S, Dematte D'Amico, J, Dilling, D, Elias, P, Ettinger, N, Falk, J, Fernández Pérez, ER, Gamez-Dubuis, A, Giessel, G, Gifford, A, Glassberg, M, Glazer, C, Golden, J, Gómez Carrera, L, Guiot, J, Hallowell, R, Hayashi, H, Hetzel, J, Hirani, N, Homik, L, Hope-Gill, B, Hotchkin, D, Ichikado, K, Ilkovich, M, Inoue, Y, Izumi, S, Jassem, E, Jones, L, Jouneau, S, Kaner, R, Kang, J, Kawamura, T, Kessler, R, Kim, Y, Kishi, K, Kitamura, H, Kolb, M, Kondoh, Y, Kono, C, Koschel, D, Kreuter, M, Kulkarni, T, Kus, J, Lebargy, F, León Jiménez, A, Luo, Q, Mageto, Y, Maher, TM, Makino, S, Marchand-Adam, S, Marquette, C, Martinez, R, Martínez, M, Maturana Rozas, R, Miyazaki, Y, Moiseev, S, Molina-Molina, M, Morrison, L, Morrow, L, Moua, T, Nambiar, A, Nishioka, Y, Nunes, H, Okamoto, M, Oldham, J, Otaola, M, Padilla, M, Park, JS, Patel, N, Pesci, A, Piotrowski, W, Pitts, L, Poonyagariyagorn, H, Prasse, A, Quadrelli, S, Randerath, W, Refini, R, Reynaud-Gaubert, M, Riviere, F, Rodríguez Portal, JA, Rosas, I, Rossman, M, Safdar, Z, Saito, T, Sakamoto, N, Salinas Fénero, M, Sauleda, J, Schmidt, S, Scholand, MB, Schwartz, M, Shapera, S, Shlobin, O, Sigal, B, Silva Orellana, A, Skowasch, D, Song, JW, Stieglitz, S, Stone, H, Strek, M, Suda, T, Sugiura, H, Takahashi, H, Takaya, H, Takeuchi, T, Thavarajah, K, Tolle, L, Tomassetti, S, Tomii, K, Valenzuela, C, Vancheri, C, Varone, F, Veeraraghavan, S, Villar, A, Weigt, S, Wemeau, L, Wuyts, W, Xu, Z, Yakusevich, V, Yamada, Y, Yamauchi, H & Ziora, D 2020, 'Nintedanib in patients with progressive fibrosing interstitial lung diseases—subgroup analyses by interstitial lung disease diagnosis in the INBUILD trial: a randomised, double-blind, placebo-controlled, parallel-group trial', The Lancet Respiratory Medicine, vol. 8, no. 5, pp. 453-460.
Miller, AJ, Stiles, LE, Sheehan, T, Bascom, R, Levy, HP, Francomano, CA & Arnold, AC 2020, 'Prevalence of hypermobile Ehlers-Danlos syndrome in postural orthostatic tachycardia syndrome', Autonomic Neuroscience: Basic and Clinical, vol. 224, 102637.
Zhao, W, Bascom, R, Toth, J & Higgins, WE 2020, Virtual radial-probe endobronchial ultrasound for image-guided bronchoscopy. in B Fei & CA Linte (eds), Medical Imaging 2020: Image-Guided Procedures, Robotic Interventions, and Modeling., 113151U, Proceedings of SPIE - The International Society for Optical Engineering, vol. 11315, SPIE, Medical Imaging 2020: Image-Guided Procedures, Robotic Interventions, and Modeling, Houston, United States, 2/16/20.


Hollin, IL, Dimmock, AEF, Bridges, JFP, Danoff, SK & Bascom, R 2019, 'Collecting patient preference information using a clinical data research network: Demonstrating feasibility with idiopathic pulmonary fibrosis', Patient Preference and Adherence, vol. 13, pp. 795-804.
Mondal, P, Yirinec, A, Midya, V, Sankoorikal, BJ, Smink, G, Khokhar, A, Abu-Hasan, M & Bascom, R 2019, 'Diagnostic value of spirometry vs impulse oscillometry: A comparative study in children with sickle cell disease', Pediatric Pulmonology, vol. 54, no. 9, pp. 1422-1430.
Zhao, W, Bascom, R, Toth, J & Higgins, WE 2019, Guidance system development for radial-probe endobronchial ultrasound bronchoscopy. in B Fei & CA Linte (eds), Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling., 109511P, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10951, SPIE, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling, San Diego, United States, 2/17/19.
Bascom, R, Schubart, JR, Mills, S, Smith, T, Zukley, LM, Francomano, CA & McDonnell, N 2019, 'Heritable disorders of connective tissue: Description of a data repository and initial cohort characterization', American Journal of Medical Genetics, Part A, vol. 179, no. 4, pp. 552-560.
Kesavan, J, Kilper, G, Williamson, M, Alstadt, V, Dimmock, A & Bascom, R 2019, 'Laboratory validation and initial field testing of an unobtrusive bioaerosol detector for health care settings', Aerosol and Air Quality Research, vol. 19, no. 2, pp. 331-344.
Ismail-Sayed, I, Twomey, K & Bascom, R 2019, 'Life Threatening Allergic Asthma in a Van Driver Transporting Laboratory Rodents', Chest, vol. 156, no. 4S, pp. A1827-A1828. <>
Zang, X, Gibbs, JD, Cheirsilp, R, Byrnes, PD, Toth, J, Bascom, R & Higgins, WE 2019, 'Optimal route planning for image-guided EBUS bronchoscopy', Computers in Biology and Medicine, vol. 112, 103361.
Schubart, JR, Schaefer, E, Janicki, P, Adhikary, S, Schilling, AL, Hakim, AJ, Bascom, R, Francomano, C & Raj, SR 2019, 'Resistance to Local Anesthesia in People with the Ehlers-Danlos Syndromes Presenting for Dental Surgery', Journal of Dental Anesthesia and Pain Medicine, vol. 19, no. 5, pp. 261-270. <>
Higgins, WE, Zang, X, Byrnes, P, Cheirsilp, R, Kuhlengel, T, Toth, JW & Bascom, R 2019, 'Route Planning for Predicting the Feasibility and Yield of Bronchoscopic Biopsy During Central-Chest Lymph Node Staging', Annals of the American Thoracic Society, vol. A2346, pp. A2346. <>
Prieto-Centurion, V, Dimmock, AEF, Krishnan, J, Pasquale, C, Lindell, K, Danoff, S, Bascom, R & Yawn, B 2019, 'The Need for Oxygen Therapy is Associated with Worse Patient-Reported Outcomes in Patients with COPD and IPF', Chest, vol. 156, no. 4S, pp. A467-A468. <>
Schubart, JR, Schaefer, E, Hakim, AJ, Francomano, CA & Bascom, R 2019, 'Use of Cluster Analysis to Delineate Symptom Profiles in an Ehlers-Danlos Syndrome Patient Population', Journal of Pain and Symptom Management, vol. 58, no. 3, pp. 427-436.
Schubart, JR, Schilling, A, Schaefer, E, Bascom, R & Francomano, C 2019, 'Use of prescription opioid and other drugs among a cohort of persons with Ehlers–Danlos syndrome: A retrospective study', American Journal of Medical Genetics, Part A, vol. 179, no. 3, pp. 397-403.


Stewart, RR, Dimmock, AEF, Green, MJ, Van Scoy, LJ, Schubart, JR, Yang, C, Farace, E, Bascom, R & Levi, BH 2019, 'An Analysis of Recruitment Efficiency for an End-of-Life Advance Care Planning Randomized Controlled Trial', American Journal of Hospice and Palliative Medicine, vol. 36, no. 1, pp. 50-54.
Mondal, P, Yirinec, A, Moses, C, Dimmock, AEF & Bascom, R 2018, 'Evaluating Children with Sickle Cell Disease and Asthma with Spirometry and Impulse.Oscillometry', Annals of the American Thoracic Society, pp. A2063. < >
Higgins, WE, Zang, X, Cheirsilp, R, Byrnes, PD, Kuhlengel, TK, Toth, J & Bascom, R 2018, Optimal multimodal virtual bronchoscopy for convex-probe endobronchial ultrasound. in B Fei & RJ Webster (eds), Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling., 1057618, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10576, SPIE, Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling, Houston, United States, 2/12/18.


Hawley, B, Cummings, KJ, Mohammed, M, Dimmock, AE & Bascom, R 2017, 'Allergic sinusitis and severe asthma caused by occupational exposure to locust bean gum: Case report', American Journal of Industrial Medicine, vol. 60, no. 7, pp. 658-663.
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, J, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, JP & Muscat, JE 2017, 'Correction: Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial. [Trials. 18, (2017) (300)] DOI: 10.1186/s13063-017-2038-9', Trials, vol. 18, no. 1, 598.
Walsh, SLF, Maher, TM, Kolb, M, Poletti, V, Nusser, R, Richeldi, L, Vancheri, C, Wilsher, ML, Antoniou, KM, Behr, J, Bendstrup, E, Brown, K, Calandriello, L, Corte, TJ, Cottin, V, Crestani, B, Flaherty, K, Glaspole, I, Grutters, J, Inoue, Y, Kokosi, M, Kondoh, Y, Kouranos, V, Kreuter, M, Johannson, K, Judge, E, Ley, B, Margaritopoulos, G, Martinez, FJ, Molina-Molina, M, Morais, A, Nunes, H, Raghu, G, Ryerson, CJ, Selman, M, Spagnolo, P, Taniguchi, H, Tomassetti, S, Valeyre, D, Wijsenbeek, M, Wuyts, W, Hansell, D, Wells, A, Zhu, PS, Yuan, Y, Yoshito Fukuda, C, Yoshimatsu, Y, Xaubet, A, Wong, AM, White, P, Westney, G, West, A, Wessendorf, T, Waseda, Y, Wang, C, Vienna, JM, Videnovic Ivanov, J, Vicens Zygmunt, V, Venero Caceres, MC, Velásquez Pinto, G, Veitch, E, Vasakova, M, Varone, F, Varela, BE, Van Hal, P, Van De Ven, M, Van Der Lee, I, Van Den Toorn, L, Urrutia Gajate, A, Urban, J, Ugarte Fornell, LG, Tzouvelekis, A, Twohig, K, Turner, A, Trujillo, S, Triani, A, Traila, D, Torres, V, Tomioka, H, Tomii, K, Tomic, R, Toma, C, Tokgoz Akyil, F, Tobino, K, Tobar, R, Tiwari, A, Tibana, R, Tian, X, Thillai, M, Tham, W, Teo, F, Tekavec Trkanjec, J, Teixeira, P, Tarpey, D, Tapias, L, Tanizawa, K, Tanino, Y, Takada, T, Tabaj, G, Szolnoki, E, Swarnakar, R, Strambu, I, Sterclova, M, Spinks, K, Soo, CI, Soltani, A, Solanki, S, Sobh, E, Soares, MR, Smith, J, Smith, B, Slocum, P, Slabbynck, H, Sivokozov, I, Shifren, A, Shen, SM, Sharp, C, Shanmuganathan, A, Sebastiani, A, Scarlata, S, Savas, R, Sasaki, S, Santeliz, J, Santana, ANC, Sanchez, R, Salinas, M, Saito, S, Ryan, F, Royo Prats, JA, Rosi, E, Rokadia, H, Robles Perez, A, Rivera Ortega, P, Rio Ramirez, M, Righetti, S, Reichner, C, Ravaglia, C, Ratanawatkul, P, Ramalingam, V, Rajasekaran, A, Radzikowska, E, Ra, SW, Quadrelli, S, Precerutti, J, Prasad, J, Popa, D, Pizzalato, S, Piotrowski, W, Pineiro, A, Piloni, D, Peros Golubicic, T, Perez, R, Pereira, C, Pereira, B, Perch, M, Patel, N, Patel, D, Papanikolaou, I, Papakosta, D, Panselinas, E, Pang, YK, Pandya, P, Padrão, E, Ozdemir Kumbasar, O, Overbeek, MJ, Otto Minasian, A, O'Riordan, D, Ora, J, Oldham, J, Okutan, O, Ohshimo, S, Oguzulgen, IK, Ogura, T, O'Donnell, T, O'Dochartaigh, C, O'Beirne, S, Novikova, L, Novelli, L, Noth, I, Nogueira Mendes Neto, N, Niroumand, M, Nieto, A, Neves, A, Nambiar, A, Nair, S, Nadama, R, Murtagh, E, Mura, M, Müller Quernheim, J, Mukhopadhyay, A, Mukherjee, S, Morisset, J, Moran, O, Mooney, J, Møller, J, Mogulkoc, N, Miyamoto, A, Milenkovic, B, Mette, S, Mejia, M, Mei, F, Mazzei, M, Matsuda, T, Mason, C, Martínez Francés, M, Mannarino, S, Mancuzo, E, Malli, F, Malhotra, P, Maillo, M, Maia, J, Mahdavian, M, Madsen, F, Luckhardt, T, Lucht, W, Low, SY, Lopez Miguel, CP, Lipchik, R, Levy, S, Levin, K, Lee, KL, Lederer, D, Lammi, MR, Kwan, HY, Kukreja, S, Kruavit, A, Kotecki, M, Kolilekas, L, Knoop, H, Kiyan, E, Kishaba, T, King Biggs, M, Khor, YH, Khan, A, Khalil, N, Kedia, R, Kebba, N, Kawano Dourado, L, Kapitan, K, Kan, CD, Kalyoncu, AF, Kalluri, M, Kabasakal, Y, Jyothula, S, Juretschke, MA, Jovanovic, D, Jonkers, R, Jo, H, Izumi, S, Ishii, H, Ikeda, S, Ibrahim, A, Hyldgaard, C, Hunninghake, G, Huie, T, Hufton, A, Hu, X, Hseih, WC, Hoyos, R, Hoyles, R, Holguin Rodriguez, O, Hogan, MP, Hodgson, U, Hilkin Sogoloff, H, Herrera, E, Henry, BM, Hellemons, M, Hecimovic, A, Hayashi, R, Hart, S, Harari, S, Haney, S, Hambly, N, Hakkim, R, Gutiérrez, M, Gripaldo, R, Gomez, A, Goh, N, Godoy, R, Gilbert, C, Giannarakis, I, Gasparini, S, Garcha, P, Furtado, S, Fois, A, Flood Page, P, Fletcher, S, Fiss, E, Figueroa Casas, J, Figueroa Casas, M, Fiddler, CA, Ferrara, G, Fernandez Casares, M, Felton, C, Faverio, P, Fabro, AT, Estrada, A, Errhalt, P, Enomoto, N, Enghelmayer, JI, El Kersh, K, Eiger, G, Dubaniewicz, A, Drakopanagiotakis, F, Disayabutr, S, Dijkstra, A, Diaz Patiño, JC, Diaz Castañon, JJ, Dhooria, S, Dhasmana, DJ, De Rosa, M, De Luca, S, Delobbe, A, Delgado, D, Delgado, C, De La Fuente, I, De Kruif, M, De Gier, M, De Andrade, J, Davidsen, JR, Daoud, B, Dalhoff, K, Cotera Solano, JV, Costa, AN, Coronel, S, Confalonieri, M, Conemans, L, Comellas, A, Colella, S, Clemente, S, Clark, J, Ciuffreda, M, Chung, CL, Chong, SG, Chirita, D, Chen, PL, Chaudhuri, N, Chambers, D, Chalmers, G, Chairman, D, Chai, GT, Chacon Chaves, R, Çetinsu, V, Ceruti, M, Ceballos Zuñiga, CO, Castillo, D, Carbone, RG, Caminati, A, Callejas González, FJ, Butler, M, Bustos, C, Bukowczan, M, Buendia, I, Brunetti, G, Brockway, B, Bresser, P, Breseghello, J, Bouros, D, Botero Zaccour, JA, Borzone, G, Borie, R, Blum, HC, Blank, J, Biswas, A, Bennett, D, Benjamin, M, Belaconi, IN, Beirne, P, Beckert, L, Bastiampillai, S, Bascom, R, Bartholmai, B, Barros, M, Ban, AYL, Balestro, E, Baldi, B, Baddini Martinez, J, Baburao, A, Babu, S, Averyanov, A, Avdeev, S, Athanazio, R, Atahan, E, Asuquo, B, Assayag, D, Antuni, J, Antillon, S, Anderson, KC, Anderson, A, Alwani, F, Altinisik, G, Alsouofi, N, Allam, JS, Al Jahdali, H, Al Farttoosi, A, Alfaro, T, Al Busaidi, N, Alavi Foumani, A, Agreda Vedia, MG, Agarwal, A, Afridi, F, Adeyeye, OO, Adegunsoye, A, Adamali, H & Abedini, A 2017, 'Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: An international case-cohort study', European Respiratory Journal, vol. 50, no. 2, 1700936.
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, J, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, JP & Muscat, JE 2017, 'Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial', Trials, vol. 18, no. 1, 300.

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