Navigation Menu

Portals Internet Clinical Trial External Search


Children (age < 18 years)
Adults (age >= 18 years)

Researcher Profile

Portals Internet Researcher Display

Robert Paulson, PhD

Robert Paulson, PhD

Professor of Veterinary Science, Veterinary and Biomedical Sciences
Scientific Program:Mechanisms of Carcinogenesis
RFP5@psu.edu

Research Interests

  • Erythropoiesis
  • Spleen
  • Friend murine leukemia virus
  • Mutation
  • Receptor Protein-Tyrosine Kinases
  • Erythrocytes
  • Leukemia
  • Anemia
  • Genes
  • Leukemia, Erythroblastic, Acute
  • Selenium
  • Proteins

Recent Publications

2023

Qian, F, Nettleford, SK, Zhou, J, Arner, BE, Hall, MA, Sharma, A, Annageldiyev, C, Rossi, RM, Tukaramrao, DB, Sarkar, D, Hegde, S, Gandhi, UH, Finch, ER, Goodfield, L, Quickel, MD, Claxton, DF, Paulson, RF & Prabhu, KS 2023, 'Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells', Cell Reports, vol. 42, no. 7, 112794. https://doi.org/10.1016/j.celrep.2023.112794
Qian, F, Arner, BE, Nettleford, SK, Paulson, RF & Prabhu, KS 2023, 'Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice', Journal of Visualized Experiments, vol. 2023, no. 191, e64834. https://doi.org/10.3791/64834
Ruan, B & Paulson, RF 2023, 'Metabolic regulation of stress erythropoiesis, outstanding questions, and possible paradigms', Frontiers in Physiology, vol. 13, 1063294. https://doi.org/10.3389/fphys.2022.1063294

2022

Qian, F, Arner, BE, Kelly, KM, Annageldiyev, C, Sharma, A, Claxton, DF, Paulson, RF & Prabhu, KS 2022, 'Interleukin-4 treatment reduces leukemia burden in acute myeloid leukemia', FASEB Journal, vol. 36, no. 5, e22328. https://doi.org/10.1096/fj.202200251R

2021

Jia, B, Zhao, C, Bayerl, M, Shike, H, Claxton, DF, Ehmann, WC, Mineishi, S, Schell, TD, Zheng, P, Zhang, Y, Shultz, LD, Prabhu, KS, Paulson, RF & Zheng, H 2022, 'A novel clinically relevant graft-versus-leukemia model in humanized mice', Journal of Leukocyte Biology, vol. 111, no. 2, pp. 427-437. https://doi.org/10.1002/JLB.5AB0820-542RR

2020

Hengst, JA, Hegde, S, Paulson, RF & Yun, JK 2020, 'Development of SKI-349, a dual-targeted inhibitor of sphingosine kinase and microtubule polymerization', Bioorganic and Medicinal Chemistry Letters, vol. 30, no. 20, 127453. https://doi.org/10.1016/j.bmcl.2020.127453
Chen, Y, Xiang, J, Qian, F, Diwakar, BT, Ruan, B, Hao, S, Sandeep Prabhu, K & Paulson, RF 2020, 'Epo receptor signaling in macrophages alters the splenic niche to promote erythroid differentiation', Blood, vol. 136, no. 2, pp. 235-246. https://doi.org/10.1182/blood.2019003480
Paulson, RF, Ruan, B, Hao, S & Chen, Y 2020, 'Stress Erythropoiesis is a Key Inflammatory Response', Cells, vol. 9, no. 3, 1894. https://doi.org/10.3390/cells9030634

2019

Diwakar, BT, Yoast, R, Nettleford, S, Qian, F, Lee, TJ, Berry, S, Huffnagle, I, Rossi, RM, Trebak, M, Paulson, RF & Prabhu, KS 2019, 'Crth2 receptor signaling down-regulates lipopolysaccharide-induced NF-αB activation in murine macrophages via changes in intracellular calcium', FASEB Journal, vol. 33, no. 11, pp. 12838-12852. https://doi.org/10.1096/fj.201802608R
Kong, Y, Jia, B, Zhao, C, Claxton, DF, Sharma, A, Annageldiyev, C, Fotos, JS, Zeng, H, Paulson, RF, Prabhu, KS & Zheng, H 2019, 'Downregulation of CD73 associates with T cell exhaustion in AML patients', Journal of Hematology and Oncology, vol. 12, no. 1, 40. https://doi.org/10.1186/s13045-019-0728-3
Matsui, Y, Zhang, Y, Paulson, RF & Lai, ZC 2019, 'Dual role of a C-terminally truncated isoform of large tumor suppressor kinase 1 in the regulation of hippo signaling and tissue growth', DNA and Cell Biology, vol. 38, no. 1, pp. 91-106. https://doi.org/10.1089/dna.2018.4340
Paulson, RF 2019, 'Epo receptor marks the spot', Blood, vol. 134, no. 5, pp. 413-414. https://doi.org/10.1182/blood.2019001581
Hao, S, Xiang, J, Wu, DC, Fraser, JW, Ruan, B, Cai, J, Patterson, AD, Lai, ZC & Paulson, RF 2019, 'Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche', Blood Advances, vol. 3, no. 14, pp. 2205-2217. https://doi.org/10.1182/bloodadvances.2019000375
Bennett, LF, Liao, C, Quickel, MD, Yeoh, BS, Vijay-Kumar, M, Hankey-Giblin, P, Prabhu, KS & Paulson, RF 2019, 'Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C', Science signaling, vol. 12, no. 598, eaap7336. https://doi.org/10.1126/scisignal.aap7336
Hao, S, Matsui, Y, Lai, ZC & Paulson, RF 2019, 'Yap1 promotes proliferation of transiently amplifying stress erythroid progenitors during erythroid regeneration', Experimental Hematology, vol. 80, pp. 42-54.e4. https://doi.org/10.1016/j.exphem.2019.11.002