Researcher Profile

Researcher Profile

Robert Paulson, PhD

Robert Paulson, PhD

Professor of Veterinary Science, Veterinary and Biomedical Sciences
Scientific Program:Mechanisms of Carcinogenesis

Research Interests

  • Erythropoiesis
  • Spleen
  • Friend murine leukemia virus
  • Mutation
  • Receptor Protein-Tyrosine Kinases
  • Anemia
  • Erythrocytes
  • Genes
  • Leukemia, Erythroblastic, Acute
  • Leukemia
  • Selenium
  • Proteins

Recent Publications


Jia, B, Zhao, C, Bayerl, M, Shike, H, Claxton, DF, Ehmann, WC, Mineishi, S, Schell, TD, Zheng, P, Zhang, Y, Shultz, LD, Prabhu, KS, Paulson, RF & Zheng, H 2021, 'A novel clinically relevant graft-versus-leukemia model in humanized mice', Journal of Leukocyte Biology.


Hengst, JA, Hegde, S, Paulson, RF & Yun, JK 2020, 'Development of SKI-349, a dual-targeted inhibitor of sphingosine kinase and microtubule polymerization', Bioorganic and Medicinal Chemistry Letters, vol. 30, no. 20, 127453.
Chen, Y, Xiang, J, Qian, F, Diwakar, BT, Ruan, B, Hao, S, Sandeep Prabhu, K & Paulson, RF 2020, 'Epo receptor signaling in macrophages alters the splenic niche to promote erythroid differentiation', Blood, vol. 136, no. 2, pp. 235-246.
Paulson, RF, Ruan, B, Hao, S & Chen, Y 2020, 'Stress Erythropoiesis is a Key Inflammatory Response', Cells, vol. 9, no. 3.


Diwakar, BT, Yoast, R, Nettleford, S, Qian, F, Lee, TJ, Berry, S, Huffnagle, I, Rossi, RM, Trebak, M, Paulson, RF & Prabhu, KS 2019, 'Crth2 receptor signaling down-regulates lipopolysaccharide-induced NF-αB activation in murine macrophages via changes in intracellular calcium', FASEB Journal, vol. 33, no. 11, pp. 12838-12852.
Kong, Y, Jia, B, Zhao, C, Claxton, DF, Sharma, A, Annageldiyev, C, Fotos, JS, Zeng, H, Paulson, RF, Prabhu, KS & Zheng, H 2019, 'Downregulation of CD73 associates with T cell exhaustion in AML patients', Journal of Hematology and Oncology, vol. 12, no. 1, 40.
Matsui, Y, Zhang, Y, Paulson, RF & Lai, ZC 2019, 'Dual role of a C-terminally truncated isoform of large tumor suppressor kinase 1 in the regulation of hippo signaling and tissue growth', DNA and Cell Biology, vol. 38, no. 1, pp. 91-106.
Paulson, RF 2019, 'Epo receptor marks the spot', Blood, vol. 134, no. 5, pp. 413-414.
Hao, S, Xiang, J, Wu, DC, Fraser, JW, Ruan, B, Cai, J, Patterson, AD, Lai, ZC & Paulson, RF 2019, 'Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche', Blood Advances, vol. 3, no. 14, pp. 2205-2217.
Bennett, LF, Liao, C, Quickel, MD, Yeoh, BS, Vijay-Kumar, M, Hankey-Giblin, P, Prabhu, KS & Paulson, RF 2019, 'Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C', Science signaling, vol. 12, no. 598, eaap7336.
Hao, S, Matsui, Y, Lai, ZC & Paulson, RF 2019, 'Yap1 promotes proliferation of transiently amplifying stress erythroid progenitors during erythroid regeneration', Experimental Hematology, vol. 80, pp. 42-54.e4.


Bresnick, EH, Hewitt, KJ, Mehta, C, Keles, S, Paulson, RF & Johnson, KD 2018, 'Mechanisms of erythrocyte development and regeneration: Implications for regenerative medicine and beyond', Development (Cambridge), vol. 145, no. 1, dev151423.
Liao, C, Sandeep Prabhu, K & Paulson, RF 2018, 'Monocyte-derived macrophages expand the murine stress erythropoietic niche during the recovery from anemia', Blood, vol. 132, no. 24, pp. 2580-2593.
Rothberg, JLM, Maganti, HB, Jrade, H, Porter, CJ, Palidwor, GA, Cafariello, C, Battaion, HL, Khan, ST, Perkins, TJ, Paulson, RF, Ito, CY & Stanford, WL 2018, 'Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis', Cell Discovery, vol. 4, no. 1, 21.
Dey, A, Allen, JN, Fraser, JW, Snyder, LM, Tian, Y, Zhang, L, Paulson, RF, Patterson, A, Cantorna, MT & Hankey-Giblin, PA 2018, 'Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease', Frontiers in immunology, vol. 9, no. MAR, 513.
Liao, C, Hardison, RC, Kennett, MJ, Carlson, BA, Paulson, RF & Prabhu, KS 2018, 'Selenoproteins regulate stress erythroid progenitors and spleen microenvironment during stress erythropoiesis', Blood, vol. 131, no. 23, pp. 2568-2580.
Bennett, LF, Liao, C & Paulson, RF 2018, Stress erythropoiesis model systems. in Methods in Molecular Biology. Methods in Molecular Biology, vol. 1698, Humana Press Inc., pp. 91-102.
Liao, C, Carlson, BA, Paulson, RF & Prabhu, KS 2018, 'The intricate role of selenium and selenoproteins in erythropoiesis', Free Radical Biology and Medicine, vol. 127, pp. 165-171.


Finch, ER, Tukaramrao, DB, Goodfield, LL, Quickel, MD, Paulson, RF & Prabhu, KS 2017, 'Activation of PPARγ by endogenous prostaglandin J2 mediates the antileukemic effect of selenium in murine leukemia', Blood, vol. 129, no. 13, pp. 1802-1810.
Hewitt, KJ, Katsumura, KR, Matson, DR, Devadas, P, Tanimura, N, Hebert, AS, Coon, JJ, Kim, JS, Dewey, CN, Keles, S, Hao, S, Paulson, RF & Bresnick, EH 2017, 'GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia', Developmental Cell, vol. 42, no. 3, pp. 213-225.e4.
Hengst, J, Dick, TE, Sharma, A, Doi, K, Hegde, S, Tan, SF, Geffert, L, Fox, TE, Sharma, AK, Desai, D, Amin, S, Kester, M, Loughran, TP, Paulson, R, Claxton, D, Wang, H-G & Yun, J 2017, 'SKI-178: A multitargeted inhibitor of sphingosine kinase and microtubule dynamics demonstrating therapeutic efficacy in acute myeloid leukemia models', Cancer Translational Medicine, vol. 3, no. 4, pp. 109-121. <;year=2017;volume=3;issue=4;spage=109;epage=121;aulast=Hengst;type=0>
Diwakar, BT, Korwar, AM, Paulson, RF & Prabhu, KS 2017, The Regulation of Pathways of Inflammation and Resolution in Immune Cells and Cancer Stem Cells by Selenium. in Advances in Cancer Research. Advances in Cancer Research, vol. 136, Academic Press Inc., pp. 153-172.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)