Researcher Profile

Researcher Profile


Patricia "Sue" Grigson-Kennedy, MS, PhD

Professor and Chair, Department of Neural and Behavioral Sciences
Scientific Program:Cancer Control
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Research Interests

Dr. Sue Grigson’s research focuses on substance abuse and addiction. She has been continuously funded by the National Institutes of Health (NIH) for more than 28 years and is the recipient of an NIH MERIT award, which recognizes the top tier of research funded by the NIH.

She is the inaugural director of Penn State Addiction Center for Translation.

  • Pharmaceutical Preparations
  • Reward
  • Cocaine
  • Saccharin
  • Cues
  • Sucrose
  • Self Administration
  • Heroin
  • Morphine
  • Street Drugs
  • Lithium Chloride
  • Appetite

Recent Publications


Donaldson, K, Buchanich, JM, Grigson-Kennedy, PS, Deneke, E, Vrana, K, Sacks, DB, Kuehn, GJ, Cardamone, D, Pesce, A, Smiley, S, Nickley, J, Krock, K, Thomas, R, Wilkerson, ML, Farag, HA, Challa, SR, Tice, AM, Wolk, DM, Prichard, J, Grant, ML, Regmi, S, Kerbacher, B, Quinton, LE, Tice, AM, Olson, J, Haynes, A, Yu, E, McCully, KS, Assi, J, Wong, M, Zarrin-Khameh, N, Nifong, TP, Hawker, CD, Carlton, GT, Rivera, JM, Foulis, PR, Zuraw, A, Morlote, D, Peker, D, Reddy, V, Harada, S, Crutchfield, C, Zander, D, Barbhuiya, MA, Pederson, EC, Straub, ML, Scott, SC, Neibauer, TL, Salter, WF, Creer, MH, Zhu, Y, Bornhorst, JA, Theobald, JP, Algeciras-Schimnich, A, Cao, L, Knox, J, Hardy, R, Texas, HJ, McGuire, MF, Hunter, RL, Brown, RE, Hicks, J, Cai, Z, Brown, RE, Ali, Y, Cheng, K, Katz, SR, Ding, Y, Vanselow, DJ, Yakovlev, MA, Lin, AY, Clark, DP, Vargas, P, Xin, X, Copper, JE, Canfield, V, Ang, K, Wang, Y, Xiao, X, De Carlo, F, Van Rossum, DB, La Rivière, PJ, Newell, J, Hossler, C, Roche, M, Warrick, J, Phaeton, R, Kesterson, J, Myers, C, Barrios, R, Mintz, P, Robyak, K, Hamilton, C, McGhee, P, Pederson, C, Straub, M, Scott, S, Neibauer, T, Salter, W, Robyak, K, Singh, N, Morlote, D, Vnencak-Jones, C, Yemelyanova, A, Harada, S, Shah, M, Moghadamtousi, SZ, Lan, C, Duose, D, Hu, P, Esquenazi, Y, Luthra, R, Ballester, LY, Koenig, AN, Liu, CG, Zhang, J, Kalia, A, Al-Habib, A, Van Arsdall, M, Dhingra, S, Patel, K & Tatevian, N 2019, 'Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019', Annals of clinical and laboratory science, vol. 49, no. 3, pp. 403-416.


Imperio, CG, McFalls, AJ, Hadad, N, Blanco-Berdugo, L, Masser, DR, Colechio, EM, Coffey, AA, Bixler, GV, Stanford, DR, Vrana, K, Grigson-Kennedy, PS & Freeman, WM 2018, 'Exposure to environmental enrichment attenuates addiction-like behavior and alters molecular effects of heroin self-administration in rats', Neuropharmacology, vol. 139, pp. 26-40.
Coffey, AA, Fang, J & Grigson-Kennedy, PS 2018, 'Heroin self-administration as a function of time of day in rats' Psychopharmacology, vol. 235, no. 10, pp. 3005-3015.


Jenney, CB, Dasalla, J & Grigson-Kennedy, PS 2018, 'Female rats exhibit less avoidance than male rats of a cocaine-, but not a morphine-paired, saccharin cue', Brain Research Bulletin, vol. 138, pp. 80-87.
Freet, C, Alexander, DN, Imperio, CG, Ruiz-Velasco, V & Grigson-Kennedy, PS 2018, 'Heroin-induced suppression of saccharin intake in OPRM1 A118G mice' Brain Research Bulletin, vol. 138, pp. 73-79.


Grigson-Kennedy, PS 2016, 'Addiction: A preclinical and clinical analysis' Brain Research Bulletin, vol. 123, pp. 1-4.
Imperio, CG, McFalls, AJ, Colechio, EM, Masser, DR, Vrana, K, Grigson-Kennedy, PS & Freeman, WM 2016, 'Assessment of individual differences in the rat nucleus accumbens transcriptome following taste-heroin extended access', Brain Research Bulletin, vol. 123, pp. 71-80.
Nyland, J, Alexander, DN & Grigson-Kennedy, PS 2016, 'Drug-Motivated behavior in rats with lesions of the thalamic orosensory area', Behavioral Neuroscience, vol. 130, no. 1, pp. 103-113.
Jenney, CB, Petko, JA, Ebersole (Anderson), B, Njatcha, CVN, Uzamere, TO, Alexander, DN, Grigson-Kennedy, PS & Levenson, R 2016, 'Early avoidance of a heroin-paired taste-cue and subsequent addiction-like behavior in rats', Brain Research Bulletin, vol. 123, pp. 61-70.
Jenney, CB, Alexander, DN, Jones, BC, Unger, EL & Grigson-Kennedy, PS 2016, 'Preweaning iron deficiency increases non-contingent responding during cocaine self-administration in rats', Physiology and Behavior, vol. 167, pp. 282-288.
Coffey, AA, Guan, Z, Grigson-Kennedy, PS & Fang, J 2016, 'Reversal of the sleep–wake cycle by heroin self-administration in rats', Brain Research Bulletin, vol. 123, pp. 33-46.
McFalls, AJ, Imperio, CG, Bixler, G, Freeman, WM, Grigson-Kennedy, PS & Vrana, K 2016, 'Reward devaluation and heroin escalation is associated with differential expression of CRF signaling genes', Brain Research Bulletin, vol. 123, pp. 81-93.
Twining, RC, Freet, C, Wheeler, RA, Reich, CG, Tompers, DA, Wolpert, SE & Grigson-Kennedy, PS 2016, 'The role of dose and restriction state on morphine-, cocaine-, and LiCl-induced suppression of saccharin intake: A comprehensive analysis', Physiology and Behavior, vol. 161, pp. 104-115.
Venkiteswaran, K, Alexander, DN, Puhl, MD, Rao, A, Piquet, AL, Nyland, J, Subramanian, MP, Iyer, P, Boisvert, MM, Handly, E, Subramanian, T & Grigson-Kennedy, PS 2016, 'Transplantation of human retinal pigment epithelial cells in the nucleus accumbens of cocaine self-administering rats provides protection from seeking', Brain Research Bulletin, vol. 123, pp. 53-60.


Freet, C, Ballard, SM, Alexander, DN, Cox, TA, Imperio, CG, Anosike, N, Carter, AB, Mahmoud, S, Ruiz-Velasco, V & Grigson-Kennedy, PS 2015, 'Cocaine-induced suppression of saccharin intake and morphine modulation of Ca2+ channel currents in sensory neurons of OPRM1 A118G mice' Physiology and Behavior, vol. 139, pp. 216-223.
Alonso-Alonso, M, Woods, SC, Pelchat, M, Grigson-Kennedy, PS, Stice, E, Farooqi, S, Khoo, CS, Mattes, RD & Beauchamp, GK 2015, 'Food reward system: Current perspectives and future research needs', Nutrition reviews, vol. 73, no. 5, pp. 296-307.
Imperio, CG & Grigson-Kennedy, PS 2015, 'Greater avoidance of a heroin-paired taste cue is associated with greater escalation of heroin self-administration in rats', Behavioral Neuroscience, vol. 129, no. 4, pp. 380-388.
Tacelosky, DM, Alexander, DN, Morse, M, Hajnal, A, Berg, A, Levenson, R & Grigson-Kennedy, PS 2015, 'Low expression of D2R and wntless correlates with high motivation for heroin', Behavioral Neuroscience, vol. 129, no. 6, pp. 744-755.
Grigson-Kennedy, PS, Colechio, EM, Power, ML, Schulkin, J & Norgren, R 2015, 'Parabrachial lesions in rats disrupt sodium appetite induced by furosemide but not by calcium deprivation' Physiology and Behavior, vol. 140, pp. 172-179.

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