Researcher Profile

Researcher Profile

Pamela Hankey Giblin, PhD

Pamela Hankey Giblin, PhD

Professor, Veterinary and Biomedical Sciences
Scientific Program:Mechanisms of Carcinogenesis
phc7@psu.edu

Research Interests

  • Macrophages
  • Receptor Protein-Tyrosine Kinases
  • Inflammation
  • Friend murine leukemia virus
  • Leukemia, Erythroblastic, Acute
  • Liver
  • Macrophage Activation
  • Therapeutics
  • Neoplasms
  • Diet
  • Obesity
  • Leukemia

Recent Publications

2019

Wang, Z, Vaughan, TY, Zhu, W, Chen, Y, Fu, G, Medrzycki, M, Nishio, H, Bunting, ST, Giblin, PH, Nusrat, A, Parkos, CA, Wang, D, Wen, R & Bunting, KD 2019, 'Gab2 and Gab3 redundantly suppress colitis by modulating macrophage and CD8+ T-cell activation', Frontiers in immunology, vol. 10, no. MAR, 486. https://doi.org/10.3389/fimmu.2019.00486

2018

Dey, A & Giblin, PH 2018, 'Insights into macrophage heterogeneity and cytokine-induced neuroinflammation in major depressive disorder', Pharmaceuticals, vol. 11, no. 3, 64. https://doi.org/10.3390/ph11030064
Dey, A, Allen, JN, Fraser, JW, Snyder, LM, Tian, Y, Zhang, L, Paulson, R, Patterson, AD, Cantorna, MT-A & Giblin, PH 2018, 'Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease', Frontiers in immunology, vol. 9, no. MAR, 513. https://doi.org/10.3389/fimmu.2018.00513
Allen, J, Zhang, J, Quickel, MD, Kennett, MJ, Patterson, AD & Giblin, PH 2018, 'Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model' Journal of Proteome Research, vol. 17, no. 9, pp. 3268-3280. https://doi.org/10.1021/acs.jproteome.8b00379

2017

Allen, JN, Dey, A, Nissly, R, Fraser, J, Yu, S, Balandaram, G, Peters, JM & Giblin, PH 2017, 'Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation', Journal of Visualized Experiments, vol. 2017, no. 122, e55445. https://doi.org/10.3791/55445
Epperly, MW, Zhang, X, Fisher, R, Hou, W, Franicola, D, Shields, D, Quickel, M, Giblin, PH, Wang, H & Greenberger, JS 2017, 'Reduced competitive repopulation capacity of multipotential hematopoietic stem cells in the bone marrow of friend virus-infected Fv2-resistant mice', In Vivo, vol. 31, no. 3, pp. 313-320. https://doi.org/10.21873/invivo.11061

2016

Feaga, HA, Quickel, MD, Giblin, PH & Keiler, KC 2016, 'Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria', PLoS Genetics, vol. 12, no. 3, e1005964. https://doi.org/10.1371/journal.pgen.1005964
Yu, S, Allen, JN, Dey, A, Zhang, L, Balandaram, G, Kennett, MJ, Xia, M, Xiong, N, Peters, JM, Patterson, AD & Giblin, PH 2016, 'The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis', Journal of Immunology, vol. 197, no. 1, pp. 256-265. https://doi.org/10.4049/jimmunol.1600450

2015

Dey, A, Allen, J & Giblin, PH 2015, 'Ontogeny and polarization of macrophages in inflammation: Blood monocytes versus tissue macrophages', Frontiers in Immunology, vol. 6, no. JAN, 00683. https://doi.org/10.3389/fimmu.2014.00683

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)