Researcher Profile

Researcher Profile

Nicholas Buchkovich, PhD

Nicholas Buchkovich, PhD

Associate Professor, Department of Microbiology and Immunology
Scientific Program:Mechanisms of Carcinogenesis

Research Interests

  • Cytomegalovirus
  • Endosomal Sorting Complexes Required for Transport
  • Viruses
  • Membranes
  • Proteins
  • Cytomegalovirus Infections
  • Endoplasmic Reticulum
  • Infections
  • Virion
  • Multivesicular Bodies
  • Viral Proteins
  • Carrier Proteins

Recent Publications


Sun, H, Du, Y, Kumar, R, Buchkovich, N & He, P 2022, 'Increased circulating microparticles contribute to severe infection and adverse outcomes of COVID-19 in patients with diabetes', American Journal of Physiology - Heart and Circulatory Physiology, vol. 323, no. 6, pp. H1176-H1193.
Martin, M, Sandhu, P, Kumar, R & Buchkovich, NJ 2022, 'The Immune-Specific E3 Ubiquitin Ligase MARCH1 Is Upregulated during Human Cytomegalovirus Infection to Regulate Iron Levels', Journal of virology, vol. 96, no. 6, e01806-21.


Kumar, R, Christensen, ND, Kaddis Maldonado, RJ, Bewley, MC, Ostman, A, Sudol, M, Chen, EC, Buchkovich, NW, Gontu, A, Surendran Nair, M, Nissly, RH, Minns, AM, Kapur, V, Rossi, R, Kuchipudi, SV, Lindner, SE, Parent, LJ, Flanagan, JM & Buchkovich, NJ 2021, 'Monoclonal antibodies to s and n sars-cov-2 proteins as probes to assess structural and antigenic properties of coronaviruses', Viruses, vol. 13, no. 10, 1899.


Sandhu, PK & Buchkovich, NJ 2020, 'Human cytomegalovirus decreases major histocompatibility complex class II by regulating class II transactivator transcript levels in a myeloid cell line', Journal of virology, vol. 94, no. 7, e01901.
Streck, NT, Zhao, Y, Sundstrom, JM & Buchkovich, NJ 2020, 'Human cytomegalovirus utilizes extracellular vesicles to enhance virus spread', Journal of virology, vol. 94, no. 16, e01227-20.
Kumar, R, Cruz, L, Sandhu, PK & Buchkovich, NJ 2020, 'UL88 mediates the incorporation of a subset of proteins into the virion tegument', Journal of virology, vol. 94, no. 14, e00474-20.


Desai, D, Lauver, M, Ostman, A, Cruz, L, Ferguson, K, Jin, G, Roper, B, Brosius, D, Lukacher, A, Amin, S & Buchkovich, N 2019, 'Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors', Bioorganic and Medicinal Chemistry, vol. 27, no. 9, pp. 1795-1803.
Takahashi, Y, Liang, X, Hattori, T, Tang, Z, He, H, Chen, H, Liu, X, Abraham, T, Imamura-Kawasawa, Y, Buchkovich, NJ, Young, MM & Wang, HG 2019, 'VPS37A directs ESCRT recruitment for phagophore closure', The Journal of cell biology, vol. 218, no. 10, pp. 3336-3354.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)