Researcher Profile
Researcher Profile
Nicholas Buchkovich, PhD
Associate Professor, Department of Microbiology and Immunology
Scientific Program:Mechanisms of Carcinogenesis
Research Interests
- Cytomegalovirus
- Endosomal Sorting Complexes Required for Transport
- Viruses
- Membranes
- Cytomegalovirus Infections
- Endoplasmic Reticulum
- Proteins
- Virion
- Infections
- Multivesicular Bodies
- Viral Proteins
- Carrier Proteins
Recent Publications
2022
Martin, M, Sandhu, P, Kumar, R & Buchkovich, NJ 2022, 'The Immune-Specific E3 Ubiquitin Ligase MARCH1 Is Upregulated during Human Cytomegalovirus Infection to Regulate Iron Levels', Journal of virology, vol. 96, no. 6, e01806-21. https://doi.org/10.1128/jvi.01806-21
2021
Kumar, R, Christensen, ND, Kaddis Maldonado, RJ, Bewley, MC, Ostman, A, Sudol, M, Chen, EC, Buchkovich, NW, Gontu, A, Surendran Nair, M, Nissly, RH, Minns, AM, Kapur, V, Rossi, R, Kuchipudi, SV, Lindner, SE, Parent, LJ, Flanagan, JM & Buchkovich, NJ 2021, 'Monoclonal antibodies to s and n sars-cov-2 proteins as probes to assess structural and antigenic properties of coronaviruses', Viruses, vol. 13, no. 10, 1899. https://doi.org/10.3390/v13101899
2020
Sandhu, PK & Buchkovich, NJ 2020, 'Human cytomegalovirus decreases major histocompatibility complex class II by regulating class II transactivator transcript levels in a myeloid cell line', Journal of virology, vol. 94, no. 7, e01901. https://doi.org/10.1128/JVI.01901-19
Streck, NT, Zhao, Y, Sundstrom, JM & Buchkovich, NJ 2020, 'Human cytomegalovirus utilizes extracellular vesicles to enhance virus spread', Journal of virology, vol. 94, no. 16, e01227-20.
Kumar, R, Cruz, L, Sandhu, PK & Buchkovich, NJ 2020, 'UL88 mediates the incorporation of a subset of proteins into the virion tegument', Journal of virology, vol. 94, no. 14, e00474-20. https://doi.org/10.1128/JVI.00474-20
2019
Desai, D, Lauver, M, Ostman, A, Cruz, L, Ferguson, K, Jin, G, Roper, B, Brosius, D, Lukacher, A, Amin, S & Buchkovich, N 2019, 'Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors', Bioorganic and Medicinal Chemistry, vol. 27, no. 9, pp. 1795-1803. https://doi.org/10.1016/j.bmc.2019.03.026
Takahashi, Y, Liang, X, Hattori, T, Tang, Z, He, H, Chen, H, Liu, X, Abraham, T, Imamura-Kawasawa, Y, Buchkovich, NJ, Young, MM & Wang, HG 2019, 'VPS37A directs ESCRT recruitment for phagophore closure', The Journal of cell biology, vol. 218, no. 10, pp. 3336-3354. https://doi.org/10.1083/jcb.201902170
2018
Streck, NT, Carmichael, J & Buchkovich, NJ 2018, 'Nonenvelopment role for the ESCRTIII complex during human cytomegalovirus infection', Journal of virology, vol. 92, no. 12, e02096-17. https://doi.org/10.1128/JVI.02096-17