Researcher Profile

Researcher Profile

Nicholas Buchkovich, PhD

Nicholas Buchkovich, PhD

Associate Professor, Department of Microbiology and Immunology
Scientific Program:Mechanisms of Carcinogenesis
njb963@psu.edu

Research Interests

  • Cytomegalovirus
  • Endosomal Sorting Complexes Required for Transport
  • Viruses
  • Membranes
  • Cytomegalovirus Infections
  • Endoplasmic Reticulum
  • Proteins
  • Virion
  • Infections
  • Multivesicular Bodies
  • Viral Proteins
  • Carrier Proteins

Recent Publications

2022

Martin, M, Sandhu, P, Kumar, R & Buchkovich, NJ 2022, 'The Immune-Specific E3 Ubiquitin Ligase MARCH1 Is Upregulated during Human Cytomegalovirus Infection to Regulate Iron Levels', Journal of virology, vol. 96, no. 6, e01806-21. https://doi.org/10.1128/jvi.01806-21

2021

Kumar, R, Christensen, ND, Kaddis Maldonado, RJ, Bewley, MC, Ostman, A, Sudol, M, Chen, EC, Buchkovich, NW, Gontu, A, Surendran Nair, M, Nissly, RH, Minns, AM, Kapur, V, Rossi, R, Kuchipudi, SV, Lindner, SE, Parent, LJ, Flanagan, JM & Buchkovich, NJ 2021, 'Monoclonal antibodies to s and n sars-cov-2 proteins as probes to assess structural and antigenic properties of coronaviruses', Viruses, vol. 13, no. 10, 1899. https://doi.org/10.3390/v13101899

2020

Sandhu, PK & Buchkovich, NJ 2020, 'Human cytomegalovirus decreases major histocompatibility complex class II by regulating class II transactivator transcript levels in a myeloid cell line', Journal of virology, vol. 94, no. 7, e01901. https://doi.org/10.1128/JVI.01901-19
Streck, NT, Zhao, Y, Sundstrom, JM & Buchkovich, NJ 2020, 'Human cytomegalovirus utilizes extracellular vesicles to enhance virus spread', Journal of virology, vol. 94, no. 16, e01227-20.
Kumar, R, Cruz, L, Sandhu, PK & Buchkovich, NJ 2020, 'UL88 mediates the incorporation of a subset of proteins into the virion tegument', Journal of virology, vol. 94, no. 14, e00474-20. https://doi.org/10.1128/JVI.00474-20

2019

Desai, D, Lauver, M, Ostman, A, Cruz, L, Ferguson, K, Jin, G, Roper, B, Brosius, D, Lukacher, A, Amin, S & Buchkovich, N 2019, 'Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors', Bioorganic and Medicinal Chemistry, vol. 27, no. 9, pp. 1795-1803. https://doi.org/10.1016/j.bmc.2019.03.026
Takahashi, Y, Liang, X, Hattori, T, Tang, Z, He, H, Chen, H, Liu, X, Abraham, T, Imamura-Kawasawa, Y, Buchkovich, NJ, Young, MM & Wang, HG 2019, 'VPS37A directs ESCRT recruitment for phagophore closure', The Journal of cell biology, vol. 218, no. 10, pp. 3336-3354. https://doi.org/10.1083/jcb.201902170

2018

Streck, NT, Carmichael, J & Buchkovich, NJ 2018, 'Nonenvelopment role for the ESCRTIII complex during human cytomegalovirus infection', Journal of virology, vol. 92, no. 12, e02096-17. https://doi.org/10.1128/JVI.02096-17

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)