Researcher Profile

Researcher Profile

Nicholas Buchkovich, PhD

Nicholas Buchkovich, PhD

Associate Professor, Department of Microbiology and Immunology
Scientific Program:Mechanisms of Carcinogenesis
njb963@psu.edu

Research Interests

  • Endosomal Sorting Complexes Required for Transport
  • Cytomegalovirus
  • Viruses
  • Membranes
  • Endoplasmic Reticulum
  • Virion
  • Cytomegalovirus Infections
  • Proteins
  • Inhibition (Psychology)
  • Multivesicular Bodies
  • Viral Proteins
  • Infection

Recent Publications

2020

Sandhu, PK & Buchkovich, NJ 2020, 'Human cytomegalovirus decreases major histocompatibility complex class II by regulating class II transactivator transcript levels in a myeloid cell line', Journal of virology, vol. 94, no. 7, e01901. https://doi.org/10.1128/JVI.01901-19
Streck, NT, Zhao, Y, Sundstrom, JM & Buchkovich, NJ 2020, 'Human cytomegalovirus utilizes extracellular vesicles to enhance virus spread', Journal of virology, vol. 94, no. 16, e01227-20.
Kumar, R, Cruz, L, Sandhu, PK & Buchkovich, NJ 2020, 'UL88 mediates the incorporation of a subset of proteins into the virion tegument', Journal of virology, vol. 94, no. 14, e00474-20. https://doi.org/10.1128/JVI.00474-20

2019

Desai, D, Lauver, M, Ostman, A, Cruz, L, Ferguson, K, Jin, G, Roper, B, Brosius, D, Lukacher, A, Amin, S & Buchkovich, N 2019, 'Inhibition of diverse opportunistic viruses by structurally optimized retrograde trafficking inhibitors', Bioorganic and Medicinal Chemistry, vol. 27, no. 9, pp. 1795-1803. https://doi.org/10.1016/j.bmc.2019.03.026
Takahashi, Y, Liang, X, Hattori, T, Tang, Z, He, H, Chen, H, Liu, X, Abraham, T, Imamura-Kawasawa, Y, Buchkovich, NJ, Young, MM & Wang, HG 2019, 'VPS37A directs ESCRT recruitment for phagophore closure', The Journal of cell biology, vol. 218, no. 10, pp. 3336-3354. https://doi.org/10.1083/jcb.201902170

2018

Streck, NT, Carmichael, J & Buchkovich, NJ 2018, 'Nonenvelopment role for the ESCRTIII complex during human cytomegalovirus infection', Journal of virology, vol. 92, no. 12, e02096-17. https://doi.org/10.1128/JVI.02096-17

2017

Cruz, L, Streck, NT, Ferguson, K, Desai, T, Desai, DH, Amin, SG & Buchkovich, NJ 2017, 'Potent inhibition of human cytomegalovirus by modulation of cellular SNARE syntaxin 5', Journal of virology, vol. 91, no. 1, e01637-16. https://doi.org/10.1128/JVI.01637-16
Cruz, L & Buchkovich, NJ 2017, 'Rerouting the traffic from a virus perspective', Frontiers in Bioscience - Landmark, vol. 22, no. 11, pp. 1845-1866. https://doi.org/10.2741/4575

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)