Researcher Profile

Researcher Profile

Mohamed Trebak, PhD

Mohamed Trebak, PhD

Professor, Department of Cellular and Molecular Physiology
Scientific Program:Mechanisms of Carcinogenesis
mzt12@psu.edu

Research Interests

  • Calcium
  • Proteins
  • Vascular Smooth Muscle
  • Cell Membrane
  • Blood Vessels
  • Smooth Muscle Myocytes
  • Endoplasmic Reticulum
  • Calcium Channels
  • Type C Phospholipases
  • Cations
  • Transient Receptor Potential Channels
  • Smooth Muscle

Recent Publications

2019

Gabani, M, Liu, J, Ait-Aissa, K, Koval, O, Kim, YR, Castañeda, D, Vikram, A, Jacobs, JS, Grumbach, I, Trebak, M, Irani, K & Kassan, M 2019, ' MiR-204 regulates type 1 IP 3 R to control vascular smooth muscle cell contractility and blood pressure ', Cell Calcium, vol. 80, pp. 18-24. https://doi.org/10.1016/j.ceca.2019.03.006
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Emrich, SM, Yoast, RE, Xin, P, Zhang, X, Pathak, T, Nwokonko, R, Gueguinou, MF, Subedi, KP, Zhou, Y, Ambudkar, IS, Hempel, N, Machaca, K, Gill, D & Trebak, M 2019, 'Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity', Journal of Biological Chemistry, vol. 294, no. 16, pp. 6318-6332. https://doi.org/10.1074/jbc.RA118.006801
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2018

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Johnson, M & Trebak, M 2018, 'Slow traffic makes for bad circulation: The case of β1 subunit of bk channels in hypertension' Hypertension, vol. 72, no. 3, pp. 585-587. https://doi.org/10.1161/HYPERTENSIONAHA.118.11237
Zhang, X, Spinelli, AM, Zhang, W & Trebak, M 2018, Study of the Endogenous CRAC Channel Using shRNA-Mediated Gene Silencing. in Methods in Molecular Biology. Methods in Molecular Biology, vol. 1843, Humana Press Inc., pp. 137-145. https://doi.org/10.1007/978-1-4939-8704-7_12

2017

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2016

Beardslee, LA, Stolwijk, J, Khaladj, DA, Trebak, M, Halman, J, Torrejon, KY, Niamsiri, N & Bergkvist, M 2016, 'A sacrificial process for fabrication of biodegradable polymer membranes with submicron thickness' Journal of Biomedical Materials Research - Part B Applied Biomaterials, vol. 104, no. 6, pp. 1192-1201. https://doi.org/10.1002/jbm.b.33464
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2015

Kassan, M, Ait-Aissa, K, Ali, M, Trebak, M & Matrougui, K 2015, 'Augmented EGF receptor tyrosine kinase activity impairs vascular function by NADPH oxidase-dependent mechanism in type 2 diabetic mouse', Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1853, no. 10, pp. 2404-2410. https://doi.org/10.1016/j.bbamcr.2015.05.032
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Kassan, M, Zhang, W, Aissa, KA, Stolwijk, J, Trebak, M & Matrougui, K 2015, 'Differential role for stromal interacting molecule 1 in the regulation of vascular function' Pflugers Archiv European Journal of Physiology, vol. 467, no. 6, 4, pp. 1195-1202. https://doi.org/10.1007/s00424-014-1556-5
Saliba, Y, Keck, M, Marchand, A, Atassi, F, Ouillé, A, Cazorla, O, Trebak, M, Pavoine, C, Lacampagne, A, Hulot, JS, Farès, N, Fauconnier, J & Lompré, AM 2015, 'Emergence of Orai3 activity during cardiac hypertrophy', Cardiovascular Research, vol. 105, no. 3, pp. 248-259. https://doi.org/10.1093/cvr/cvu207
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Zhang, W, Zhang, X, González-Cobos, JC, Stolwijk, JA, Matrougui, K & Trebak, M 2015, 'Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia', Journal of Biological Chemistry, vol. 290, no. 8, pp. 5015-5027. https://doi.org/10.1074/jbc.M114.625822
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Kassan, M, Choi, SK, Galán, M, Trebak, M, Belmadani, S & Matrougui, K 2015, 'Nuclear factor kappa B inhibition improves conductance artery function in type 2 diabetic mice' Diabetes/Metabolism Research and Reviews, vol. 31, no. 1, pp. 39-49. https://doi.org/10.1002/dmrr.2542
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Spinelli, AM, Liu, Y, Sun, LY, González-Cobos, JC, Backs, J, Trebak, M & Singer, HA 2015, 'Smooth muscle CaMKIIδ promotes allergen-induced airway hyperresponsiveness and inflammation', Pflugers Archiv European Journal of Physiology, vol. 467, no. 12, pp. 2541-2554. https://doi.org/10.1007/s00424-015-1713-5

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