Researcher Profile

Researcher Profile

Margherita Teresa-Anna Cantorna, PhD

Margherita Teresa-Anna Cantorna, PhD

Distinguished Professor, Veterinary and Biomedical Sciences
Scientific Program:Mechanisms of Carcinogenesis
Disease Teams:
Pediatric Cancer

Research Interests

  • Vitamin D
  • Calcitriol Receptors
  • T-Lymphocytes
  • Calcitriol
  • Inflammatory Bowel Diseases
  • Infection
  • Immune System
  • Knockout Mice
  • Inflammation
  • Multiple Sclerosis
  • Diet
  • Natural Killer T-Cells

Recent Publications


Cantorna, MT, Rogers, CJ & Arora, J 2019, 'Aligning the Paradoxical Role of Vitamin D in Gastrointestinal Immunity', Trends in Endocrinology and Metabolism, vol. 30, no. 7, pp. 459-466.
Tian, Y, Gui, W, Smith, PB, Koo, I, Murray, IA, Cantorna, MT, Perdew, GH & Patterson, AD 2019, 'Isolation and Identification of Aryl Hydrocarbon Receptor Modulators in White Button Mushrooms (Agaricus bisporus)', Journal of agricultural and food chemistry, vol. 67, no. 33, pp. 9286-9294.
Snyder, LM, McDaniel, KL, Tian, Y, Wei, CH, Kennett, MJ, Patterson, AD, Catharine Ross, A & Cantorna, MT 2019, 'Retinoic acid mediated clearance of Citrobacter rodentium in vitamin A deficient mice requires CD11b+ and T cells', Frontiers in immunology, vol. 10, no. JAN.
Cantorna, MT, Snyder, L & Arora, J 2019, 'Vitamin A and vitamin D regulate the microbial complexity, barrier function, and the mucosal immune responses to ensure intestinal homeostasis', Critical Reviews in Biochemistry and Molecular Biology, vol. 54, no. 2, pp. 184-192.
Cantorna, MT, Lin, YD, Arora, J, Bora, S, Tian, Y, Nichols, RG & Patterson, AD 2019, 'Vitamin D Regulates the Microbiota to Control the Numbers of RORĪ³t/FoxP3+ Regulatory T Cells in the Colon', Frontiers in immunology, vol. 10.
Lin, YD, Arora, J, Diehl, K, Bora, SA & Cantorna, MT 2019, 'Vitamin D is required for ILC3 derived IL-22 and protection from Citrobacter rodentium infection', Frontiers in immunology, vol. 10, no. JAN.


Dey, A, Allen, JN, Fraser, JW, Snyder, LM, Tian, Y, Zhang, L, Paulson, RF, Patterson, A, Cantorna, MT & Hankey-Giblin, PA 2018, 'Neuroprotective role of the ron receptor tyrosine kinase underlying central nervous system inflammation in health and disease', Frontiers in immunology, vol. 9, no. MAR, 513.
Tian, Y, Nichols, RG, Roy, P, Gui, W, Smith, PB, Zhang, J, Lin, Y, Weaver, V, Cai, J, Patterson, AD & Cantorna, MT 2018, 'Prebiotic effects of white button mushroom (Agaricus bisporus) feeding on succinate and intestinal gluconeogenesis in C57BL/6 mice', Journal of Functional Foods, vol. 45, pp. 223-232.
Bora, SA, Kennett, MJ, Smith, PB, Patterson, AD & Cantorna, MT 2018, 'Regulation of vitamin D metabolism following disruption of the microbiota using broad spectrum antibiotics', Journal of Nutritional Biochemistry, vol. 56, pp. 65-73.
Bora, SA, Kennett, MJ, Smith, PB, Patterson, AD & Cantorna, MT 2018, 'The gut microbiota regulates endocrine vitamin D metabolism through fibroblast growth factor 23', Frontiers in immunology, vol. 9, no. MAR, 408.
Tian, Y, Nichols, RG, Cai, J, Patterson, AD & Cantorna, MT 2018, 'Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis', Journal of Nutritional Biochemistry, vol. 54, pp. 28-34.


Cantorna, MT 2017, 'Comment on "diet-derived short chain fatty acids stimulate intestinal epithelial cells to induce mucosal tolerogenic dendritic cells"', Journal of Immunology, vol. 198, no. 11.
James, J, Weaver, V & Cantorna, MT 2017, 'Control of circulating IgE by the Vitamin D receptor in vivo involves B cell intrinsic and extrinsic mechanisms', Journal of Immunology, vol. 198, no. 3, pp. 1164-1171.
Bora, S & Cantorna, MT 2017, 'The role of UVR and Vitamin D on T cells and inflammatory bowel disease', Photochemical and Photobiological Sciences, vol. 16, no. 3, pp. 347-353.
Cantorna, MT & Bruce, D 2017, Vitamin D and Inflammatory Bowel Disease. in Health, Disease and Therapeutics. vol. 2, Elsevier Inc., pp. 1025-1036.


Cantorna, MT-A 2016, 'IBD: Vitamin D and IBD: Moving towards clinical trials', Nature Reviews Gastroenterology and Hepatology, vol. 13, no. 6, pp. 322-323.
Cantorna, MT 2016, 'Vitamin D and lung infection', Infection and Immunity, vol. 84, no. 11, pp. 3094-3096.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)