Mack Ruffin, MD, MPH - Penn State Cancer Institute
Researcher Profile

Mack Ruffin, MD, MPH
Hershey Company Professor, Dr. and Mrs. Forney P. George Fellow, Department of Family and Community Medicine
Professor, Department of Public Health Sciences
Professor, Department of Public Health Sciences
Scientific Program:Cancer Control
Recent Publications
2025
Reiter, PL, Shoben, AB, Cooper, S, Ashcraft, AM, Mitchell, EMK, Dignan, M, Cromo, M, Walunis, J, Flinner, D, Boatman, D, Hauser, L, Ruffin, MT, Belinson, JL, Anderson, RT, Kennedy-Rea, S, Paskett, ED & Katz, ML 2025, 'A Mail-Based HPV Self-Collection Program to Increase Cervical Cancer Screening in Appalachia: Results of a Group Randomized Trial', Cancer Epidemiology Biomarkers and Prevention, vol. 34, no. 1, pp. 159-165. https://doi.org/10.1158/1055-9965.EPI-24-0999
Katz, ML, Shoben, A, Ashcraft, AM, Mitchell, E, Dignan, M, Cooper, S, Cromo, M, Walunis, J, Flinner, D, Boatman, D, Hauser, L, Ruffin, MT & Reiter, PL 2025, 'Results of a Human Papillomavirus Self-Collection Educational Intervention for Health Care Providers in Appalachia', Women's Health Reports, vol. 6, no. 1, pp. 113-121. https://doi.org/10.1089/whr.2024.0121
2024
Scott, AM, Jodi Van Scoy, L, Chinchilli, VM, Ruffin, MT, Wasserman, E & Jimbo, M 2024, 'Communication quality predicts patients’ colorectal cancer screening behavior', Social Science and Medicine, vol. 358, 117199. https://doi.org/10.1016/j.socscimed.2024.117199
Wong, A, Morgis, R, Entenman, J, Ramirez, SI, Hays, AL, Wright, TS, Scartozzi, CM, Ruffin, MT & Moss, JL 2024, 'Exploratory Analysis of Concordance Between Clinician-Collected and Self-Sampled Human Papillomavirus Tests in a Small Cohort of Average- and High-Risk Patients', Women's Health Reports, vol. 5, no. 1, pp. 259-266. https://doi.org/10.1089/whr.2024.0004
Moss, JL, Entenman, J, Stoltzfus, K, Liao, J, Onega, T, Reiter, PL, Klesges, LM, Garrow, G & Ruffin, MT 2024, 'Self-sampling tools to increase cancer screening among underserved patients: a pilot randomized controlled trial', JNCI Cancer Spectrum, vol. 8, no. 1, pkad103. https://doi.org/10.1093/jncics/pkad103
2023
Calo, WA, Shah, PD, Fogel, BN, Ruffin IV, MT, Moss, JL, Hausman, BL, Segel, JE, Francis, E, Schaefer, E, Bufalini, CM, Johnston, N, Hogentogler, E & Kraschnewski, JL 2023, 'Increasing the adoption of evidence-based communication practices for HPV vaccination in primary care clinics: The HPV ECHO study protocol for a cluster randomized controlled trial', Contemporary Clinical Trials, vol. 131, 107266. https://doi.org/10.1016/j.cct.2023.107266
2022
Moss, JL, Leach, K, Stoltzfus, KC, Granzow, M, Reiter, PL, Onega, T, Klesges, LM & Ruffin, MT 2022, 'Multilevel Associations with Cancer Screening Among Women in Rural, Segregated Communities Within the Northeastern USA: a Mixed-Methods Study', Journal of Cancer Education, vol. 37, no. 6, pp. 1982-1992. https://doi.org/10.1007/s13187-021-02069-0
Calo, WA, Lennon, RP, Ruffin IV, MT, Keller, C, Spanos, K, D'Souza, G & Kraschnewski, JL 2022, 'Support for HPV vaccine school-entry requirements in the United States: The role of exemption policies', Vaccine, vol. 40, no. 51, pp. 7426-7432. https://doi.org/10.1016/j.vaccine.2022.08.019
Shen, C, Kwon, M, Moss, JL, Schaefer, E, Zhou, S, Dodge, D & Ruffin, MT 2022, 'Utilization of Mammography During the Last Year of Life Among Older Breast Cancer Survivors', Journal of Women's Health, vol. 31, no. 7, pp. 941-948. https://doi.org/10.1089/jwh.2021.0517
2021
Shen, C, Klein, RW, Moss, JL, Dodge, DG, Chetlen, AL, Stahl, KA, Zhou, S, Leslie, DL, Ruffin, MT & Lengerich, EJ 2021, 'Association Between Dense Breast Legislation and Cancer Stage at Diagnosis', American Journal of Preventive Medicine, vol. 61, no. 6, pp. 890-899. https://doi.org/10.1016/j.amepre.2021.05.020
Shen, Y, Sen, A, Turgeon, DK, Ren, J, Graifman, G, Ruffin, MT, Smith, WL, Brenner, DE & Djuric, Z 2022, 'Changes in Serum, Red Blood Cell, and Colonic Fatty Acids in a Personalized Omega-3 Fatty Acid Supplementation Trial', Nutrition and cancer, vol. 74, no. 2, pp. 565-578. https://doi.org/10.1080/01635581.2021.1903950
Moss, JL, Popalis, M, Ramirez, SI, Reedy-Cooper, A & Ruffin, MT 2022, 'Disparities in Cancer Screening: The Role of County-Level Metropolitan Status and Racial Residential Segregation', Journal of Community Health, vol. 47, no. 1, pp. 168-178. https://doi.org/10.1007/s10900-021-01035-7
Hughes, A, Dahmus, J, Rivas, G, Hummer, B, Chen See, JR, Wright, JR, Lamendella, R, Schmitz, KH, Sciamanna, C, Ruffin, M, Patterson, AD, Loomba, R & Stine, JG 2021, 'Exercise Training Reverses Gut Dysbiosis in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis: A Proof of Concept Study', Clinical Gastroenterology and Hepatology, vol. 19, no. 8, pp. 1723-1725. https://doi.org/10.1016/j.cgh.2020.08.063
Van Scoy, LJ, Miller, EL, Snyder, B, Wasserman, E, Chinchilli, VM, Zgierska, AE, Rabago, D, Lennon, CL, Lipnick, D, Toyobo, O, Ruffin, MT & Lennon, RP 2021, 'Knowledge, perceptions, and preferred information sources related to covid-19 among central pennsylvania adults early in the pandemic: A mixed methods cross-sectional survey', Annals of family medicine, vol. 19, no. 4, pp. 293-301. https://doi.org/10.1370/afm.2674
Manzor Mitrzyk, B, Plegue, MA, Kadri, R, Danak, SU, Hubbard, JD, Kaip, EA, Roberson, DN, Ellingrod, VL, Farris, KB, Ruffin, MT, Klinkman, MS & Buis, LR 2021, 'Pharmacogenomic testing for mental health (Part I): Documenting early adopter perceptions of use for eight scenarios', Personalized Medicine, vol. 18, no. 3, pp. 223-232. https://doi.org/10.2217/pme-2020-0083
Manzor Mitrzyk, B, Plegue, MA, Kadri, R, Danak, SU, Hubbard, JD, Kaip, EA, Roberson, DN, Roy, S, Guetterman, TC, Ellingrod, VL, Farris, KB, Ruffin Iv, MT, Klinkman, MS & Buis, LR 2021, 'Pharmacogenomic testing for mental health (Part II): Qualitative analysis of early adopter prescriber perceptions', Personalized Medicine, vol. 18, no. 3, pp. 233-240. https://doi.org/10.2217/pme-2020-0084
Ruffin, MT, Hade, EM, Fahey, P, Christian, LM, Paskett, ED & Harper, DM 2021, 'Predictors of Human Papillomavirus Seropositivity in Appalachian Women Aged 18 to 26 Years', Sexually transmitted diseases, vol. 48, no. 9, pp. 693-699. https://doi.org/10.1097/OLQ.0000000000001416