Researcher Profile

Researcher Profile

Lisa Shantz, PhD

Lisa Shantz, PhD

Associate Professor, Department of Cellular and Molecular Physiology
Scientific Program:Mechanisms of Carcinogenesis
lms17@psu.edu

Research Interests

  • Ornithine Decarboxylase
  • Polyamines
  • Neoplasms
  • Adenosylmethionine Decarboxylase
  • Carcinogenesis
  • Skin
  • Transgenic Mice
  • Enzymes
  • Growth
  • Messenger RNA
  • Spermine
  • Proteins

Recent Publications

2019

Stump, CL, Feehan, RP, Jordan, T, Shantz, L & Nowotarski, SL 2019, 'Knocking down raptor in human keratinocytes affects ornithine decarboxylase in a post-transcriptional Manner following ultraviolet B exposure', Amino Acids. https://doi.org/10.1007/s00726-019-02732-3

2018

Feehan, RP, Nelson, A & Shantz, L 2018, 'Inhibition of mTORC2 enhances UVB-induced apoptosis in keratinocytes through a mechanism dependent on the FOXO3a transcriptional target NOXA but independent of TRAIL', Cellular Signalling, vol. 52, pp. 35-47. https://doi.org/10.1016/j.cellsig.2018.08.018
Nowotarski, SL, Feehan, RP, Presloid, C & Shantz, L 2018, 'Knockout of Raptor destabilizes ornithine decarboxylase mRNA and decreases binding of HuR to the ODC transcript in cells exposed to ultraviolet-B irradiation', Biochemical and Biophysical Research Communications, vol. 505, no. 4, pp. 1022-1026. https://doi.org/10.1016/j.bbrc.2018.10.019

2016

Nowotarski, SL, Origanti, S, Sass-Kuhn, S & Shantz, L 2016, 'Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin', Amino Acids, vol. 48, no. 10, pp. 2303-2311. https://doi.org/10.1007/s00726-016-2261-9
Feehan, RP & Shantz, L 2016, 'Molecular signaling cascades involved in nonmelanoma skin carcinogenesis', Biochemical Journal, vol. 473, no. 19, pp. 2973-2994. https://doi.org/10.1042/BCJ20160471
Feehan, RP & Shantz, L 2016, 'Negative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation', Cellular Signalling, vol. 28, no. 8, pp. 798-809. https://doi.org/10.1016/j.cellsig.2016.03.013

Clinical Trials Search


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