Researcher Profile

Researcher Profile

Junjia Zhu, MS, PhD

Junjia Zhu, MS, PhD

Assistant Professor, Department of Public Health Sciences
Division of Biostatistics and Bioinformatics
Scientific Program:Cancer Control

Research Interests

  • Neoplasms
  • Therapeutics
  • Colorectal Neoplasms
  • Smoking
  • Pregnancy
  • Mothers
  • Tobacco Products
  • Survival
  • Nicotine
  • Circulating Neoplastic Cells
  • Population
  • Postpartum Period

Clinical Trials

Observational Study to Determine the Differences in Molecular Characterization between Smokers vs. Non-smokers in Patients with Stage IV Bladder Cancer and their Correlation with Clinical Outcome
Tissue and Blood Collection from Patients with Suspected Lung Cancer

Recent Publications


Zhu, J, Hussain, M, Joshi, A, Truica, C, Nesterova, D, Collins, J, Saunders, EFH, Hayes, M, Drabick, J & Joshi, M 2019, 'Effect of creative writing on mood in patients with cancer' BMJ Supportive and Palliative Care.
Pu, JJ, Poulose, J, Malysz, J, Zhu, J, Fanburg-Smith, J, Claxton, D & Bayerl, M 2019, 'Impact of ruxolitinib on myelofibrosis patients post allogeneic stem cell transplant—a pilot study', British Journal of Haematology.
Zhu, J, Nelson, K, Toth, J & Muscat, J 2019, 'Nicotine dependence as an independent risk factor for atherosclerosis in the National Lung Screening Trial' BMC Public Health, vol. 19, no. 1, 103.


Van De Louw, A, Desai, RJ, Zhu, J & Claxton, D 2018, 'Characteristics of early acute respiratory distress syndrome in newly diagnosed acute myeloid leukemia', Leukemia and Lymphoma, vol. 59, no. 10, pp. 2369-2376.
Chen, K-M, Sun, Y-W, Cooper, TK, Benitez, G, Aliaga, C, Zhu, J, Gowda, K, Amin, S & El-Bayoumy, K 2018, 'Comparative Tumorigenicity and DNA Damage Induced by Dibenzo[ def,p]chrysene and Its Metabolites in the Mouse Ovary' Chemical Research in Toxicology, vol. 31, no. 11, pp. 1111-1118.
Joseph, S, Krebs, NM, Zhu, J, Wert, Y, Goel, R, Reilly, SM, Sun, D, Richie, J, Nikiforov, I, Cheriyath, P & Muscat, J 2018, 'Differences in nicotine dependence, smoke exposure and consumer characteristics between smokers of machine-injected roll-your-own cigarettes and factory-made cigarettes', Drug and Alcohol Dependence, vol. 187, pp. 109-115.
Chen, K-M, Guttenplan, JB, Sun, Y-W, Cooper, T, Shalaby, NAE, Kosinska, W, Benitez, G, Aliaga, C, Zhu, J, Liao, JJ, Gowda, K, Amin, S, Stoner, G & El-Bayoumy, K 2018, 'Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNAAdducts, Mutagenesis, and Tumorigenesis in the Mouse Oral Cavity', Cancer Prevention Research, vol. 11, no. 3, pp. 157-164.
Pameijer, CR, Leung, A, Neves, R & Zhu, J 2018, 'Indocyanine green and fluorescence lymphangiography for sentinel node identification in patients with melanoma', American Journal of Surgery, vol. 216, no. 3, pp. 558-561.
Zaorsky, N, Ahmed, AA, Zhu, J, Yoo, SK, Fuller, CD, Thomas, CR, Choi, M & Holliday, EB 2019, 'Industry Funding Is Correlated With Publication Productivity of US Academic Radiation Oncologists', Journal of the American College of Radiology, vol. 16, no. 2, pp. 244-251.
Chen, A, Krebs, NM, Zhu, J & Muscat, J 2018, 'Nicotine metabolite ratio predicts smoking topography: The Pennsylvania Adult Smoking Study', Drug and Alcohol Dependence, vol. 190, pp. 89-93.


Allen, SI, Foulds, J, Pachas, GN, Veldheer, S, Cather, C, Azzouz, N, Hrabovsky, S, Hameed, A, Yingst, J, Hammett, E, Modesto, J, Krebs, NM, Zhu, J, Liao, JJ, Muscat, J, Richie, J & Evins, AE 2017, 'A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol', BMC Public Health, vol. 17, no. 1, pp. 1-13.
Felts, JL, Zhu, J, Han, B, Smith, JS & Truica, C 2017, 'An Analysis of Oncotype DX Recurrence Scores and Clinicopathologic Characteristics in Invasive Lobular Breast Cancer', Breast Journal, vol. 23, no. 6, pp. 677-686.
Lee, S, Zhu, J, Salzberg, AC, Zhang, B, Liu, D, Muscat, J, Langan, ST & Connor, J 2017, 'Analysis of single nucleotide variants of HFE gene and association to survival in the Cancer Genome Atlas GBM data', PloS one, vol. 12, no. 3, e0174778.
Kokolus, KM, Zhang, Y, Sivik, JM, Schmeck, C, Zhu, J, Repasky, EA, Drabick, J & Schell, T 2018, 'Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in mice', OncoImmunology, vol. 7, no. 3, e1405205.
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, JJ, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, J & Muscat, J 2017, 'Correction: Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial. [Trials. 18, (2017) (300)] DOI: 10.1186/s13063-017-2038-9' Trials, vol. 18, no. 1, 598.
Alexander, C, Zhu, J, Paul, I & Kjerulff, K 2017, 'Fathers make a difference: positive relationships with mother and baby in relation to infant colic', Child: Care, Health and Development, vol. 43, no. 5, pp. 687-696.
Sun, Y-W, Chen, K-M, Imamura, Y, Salzberg, AC, Cooper, TK, Caruso, C, Aliaga, C, Zhu, J, Gowda, K, Amin, S & El-Bayoumy, K 2017, 'Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene', PloS one, vol. 12, no. 10, e0186873.
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, JJ, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, J & Muscat, J 2017, 'Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial', Trials, vol. 18, no. 1, 300.
Chen, A, Krebs, NM, Zhu, J, Sun, D, Stennett, A & Muscat, J 2017, 'Sex/Gender Differences in Cotinine Levels among Daily Smokers in the Pennsylvania Adult Smoking Study', Journal of Women's Health, vol. 26, no. 11, pp. 1222-1230.
Small, J, Washburn, E, Millington, K, Zhu, J & Holder, S 2017, 'The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors', Oncotarget, vol. 8, no. 56, pp. 95116-95134.


Liu, Y, Zhu, J & Lin, DKJ 2016, 'A generalized likelihood ratio test for monitoring profile data' Paper presented at 12th International Workshop on Intelligent Statistical Quality Control, IWISQC 2016, Hamburg, Germany, 8/16/16 - 8/19/16, pp. 309-325.
Tan, SF, Liu, X, Fox, TE, Barth, BM, Sharma, A, Turner, SD, Awwad, A, Dewey, A, Doi, K, Spitzer, B, Shah, MV, Morad, SAF, Desai, D, Amin, S, Zhu, J, Liao, JJ, Yun, J, Kester, M, Claxton, D, Wang, H-G, Cabot, MC, Schuchman, EH, Levine, RL, Feith, DJ & Loughran, TP 2016, 'Acid ceramidase is upregulated in AML and represents a novel therapeutic target', Oncotarget, vol. 7, no. 50, pp. 83208-83222.
Malysz, J, Erdman, P, Klapper, J, Zhu, J, Creer, M & Bayerl, M 2016, 'Clinical Implications of CD30 Expression in Aggressive B-Cell Lymphomas', Clinical Lymphoma, Myeloma and Leukemia, vol. 16, no. 8, pp. 429-433.
Krebs, NM, Chen, A, Zhu, J, Sun, D, Liao, JJ, Stennett, AL & Muscat, J 2016, 'Comparison of Puff Volume with Cigarettes per Day in Predicting Nicotine Uptake among Daily Smokers', American Journal of Epidemiology, vol. 184, no. 1, pp. 48-57.
LaRosa, CL, Quach, KA, Koons, K, Kunselman, AR, Zhu, J, Thiboutot, DM & Zaenglein, AL 2016, 'Consumption of dairy in teenagers with and without acne', Journal of the American Academy of Dermatology, vol. 75, no. 2, pp. 318-322.
Malysz, J, Talamo, G, Zhu, J, Clarke, LE, Bayerl, M, Ali, L, Helm, K & Chung, C 2016, 'Cutaneous involvement in multiple myeloma (MM): A case series with clinicopathologic correlation', Journal of the American Academy of Dermatology, vol. 74, no. 5, pp. 878-884.
Zheng, H, Liu, X, Zhang, J, Rice, SJ, Wagman, M, Kong, Y, Zhu, L, Zhu, J, Joshi, M & Belani, C 2016, 'Expression of PD-1 on CD4+ T cells in peripheral blood associates with poor clinical outcome in non-small cell lung cancer', Oncotarget, vol. 7, no. 35, pp. 56233-56240.
Hackman, N, Alligood-Percoco, N, Martin, A, Zhu, J & Kjerulff, K 2016, 'Reduced breastfeeding rates in firstborn late preterm and early term infants', Breastfeeding Medicine, vol. 11, no. 3, pp. 119-125.
Joshi, M, Vasekar, M, Grivas, P, Emamekhoo, H, Hsu, JA, Miller, VA, Stephens, PJ, Ali, SM, Ross, JS, Zhu, J, Warrick, J, Drabick, J, Holder, S, Kaag, MG, Li, M & Pal, SK 2016, 'Relationship of smoking status to genomic profile, chemotherapy response and clinical outcome in patients with advanced urothelial carcinoma', Oncotarget, vol. 7, no. 32, pp. 52442-52449.
Chetlen, A, Brown, KL, King, SH, Kasales, C, Schetter, S, Mack, J & Zhu, J 2016, 'Scatter radiation dose from digital screening mammography measured in a representative patient population', American Journal of Roentgenology, vol. 206, no. 2, pp. 359-365.
McCall-Hosenfeld, J, Phiri, K, Schaefer, E, Zhu, J & Kjerulff, K 2016, 'Trajectories of Depressive Symptoms Throughout the Peri-and Postpartum Period: Results from the First Baby Study', Journal of Women's Health, vol. 25, no. 11, pp. 1112-1121.


Kuder, CH, Weivoda, MM, Zhang, Y, Zhu, J, Neighbors, J, Wiemer, DF & Hohl, R 2015, '3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines' Lipids, vol. 50, no. 12, pp. 1195-1207.
Blake, N, Zhu, J, Hernandez, G & Juliano, P 2015, 'A retrospective review of diagnostic testing for onychomycosis of the foot', Journal of the American Podiatric Medical Association, vol. 105, no. 6, pp. 503-508.
Kaifi, JT, Kunkel, M, Das, A, Harouaka, RA, Dicker, DT, Li, G, Zhu, J, Clawson, G, Yang, Z, Reed, MF, Gusani, NJ, Kimchi, ET, Staveley-O’Carroll, KF, Zheng, S & El-Deiry, WS 2015, 'Circulating tumor cell isolation during resection of colorectal cancer lung and liver metastases: A prospective trial with different detection techniques', Cancer Biology and Therapy, vol. 16, no. 5, pp. 699-708.
Kaifi, JT, Kunkel, M, Dicker, DT, Joude, J, Allen, JE, Das, A, Zhu, J, Yang, Z, Sarwani, N, Li, G, Staveley-O’Carroll, KF & El-Deiry, WS 2015, 'Circulating tumor cell levels are elevated in colorectal cancer patients with high tumor burden in the liver' Cancer Biology and Therapy, vol. 16, no. 5, pp. 690-698.
Das, A, Kunkel, M, Joudeh, J, Dicker, DT, Scicchitano, A, Allen, JE, Sarwani, N, Yang, Z, Kaifi, J, Zhu, J, Liao, JJ & El-Deiry, WS 2015, 'Clinico-pathological correlation of serial measurement of circulating tumor cells in 24 metastatic colorectal cancer patients receiving chemotherapy reveals interpatient heterogeneity correlated with CEA levels but independent of KRAS and BRAF mutation' Cancer Biology and Therapy, vol. 16, no. 5, pp. 709-713.
Talamo, G, Dimaio, C, Abbi, KKS, Pandey, MK, Malysz, J, Creer, M, Zhu, J, Mir, MA & Varlotto, JM 2015, 'Current role of radiation therapy for multiple myeloma' Frontiers in Oncology, vol. 5, no. FEB, 40.
Holder, S, Drabick, J, Zhu, J & Joshi, M 2015, 'Dexamethasone may be the most efficacious corticosteroid for use as monotherapy in castration-resistant prostate cancer' Cancer Biology and Therapy, vol. 16, no. 2, pp. 207-209.
Bicking Kinsey, C, Baptiste-Roberts, K, Zhu, J & Kjerulff, K 2015, 'Effect of Multiple Previous Miscarriages on Health Behaviors and Health Care Utilization During Subsequent Pregnancy' Women's Health Issues, vol. 25, no. 2, pp. 155-161.
Talamo, G, Mir, MA, Pandey, MK, Zhu, J, Creer, M & Malysz, J 2015, 'Estimation of daily proteinuria in patients with amyloidosis by using the protein-to-creatinine ratio in random urine samples' Rare Tumors, vol. 7, no. 1, 5686, pp. 16-19.
Lee, S, Slagle-Webb, B, Sheehan, JM, Zhu, J, Muscat, J, Glantz, M & Connor, J 2015, 'HFE polymorphisms affect survival of brain tumor patients' Journal of neuro-oncology, vol. 122, no. 1, pp. 97-104.
Haakenson, JK, Khokhlatchev, AV, Choi, YJ, Linton, SS, Zhang, P, Zaki, PM, Fu, C, Cooper, T, Manni, A, Zhu, J, Fox, TE, Dong, C & Kester, M 2015, 'Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells' Journal of Biological Chemistry, vol. 290, no. 13, pp. 8632-8643.
Rice, SJ, Liu, X, Miller, B, Joshi, M, Zhu, J, Caruso, C, Gilbert, C, Toth, J, Reed, MF, Rassaei, N, Das, A, Barochia, A, El-Bayoumy, K & Belani, C 2015, 'Proteomic profiling of human plasma identifies apolipoprotein E as being associated with smoking and a marker for squamous metaplasia of the lung' Proteomics, vol. 15, no. 18, pp. 3267-3277.
Phelan, AL, DiBenedetto, MR, Paul, I, Zhu, J & Kjerulff, K 2015, 'Psychosocial Stress During First Pregnancy Predicts Infant Health Outcomes in the First Postnatal Year', Maternal and child health journal, vol. 19, no. 12, pp. 2587-2597.
Bhimanapati, GR, Lin, Z, Meunier, V, Jung, Y, Cha, J, Das, S, Xiao, D, Son, Y, Strano, MS, Cooper, VR, Liang, L, Louie, SG, Ringe, E, Zhou, W, Kim, SS, Naik, RR, Sumpter, BG, Terrones, H, Xia, F, Wang, Y, Zhu, J, Akinwande, D, Alem, N, Schuller, JA, Schaak, RE, Terrones Maldonado, M & Robinson, JA 2015, 'Recent Advances in Two-Dimensional Materials beyond Graphene', ACS Nano, vol. 9, no. 12, pp. 11509-11539.
Veldheer, S, Yingst, J, Zhu, J & Foulds, J 2015, 'Ten-year weight gain in smokers who quit, smokers who continued smoking and never smokers in the United States, NHANES 2003-2012' International Journal of Obesity, vol. 39, no. 12, pp. 1727-1732.
Manahan, E, Wang, L, Chen, S, Dickson-Witmer, D, Zhu, J, Holmes, D & Kass, R 2015, 'What is a Breast Surgeon Worth? A Salary Survey of the American Society of Breast Surgeons', Annals of Surgical Oncology, vol. 22, no. 10, pp. 3257-3263.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)