Researcher Profile

Researcher Profile

Junjia Zhu, MS, PhD

Junjia Zhu, MS, PhD

Associate Professor, Department of Public Health Sciences
Division of Biostatistics and Bioinformatics
Scientific Program:Cancer Control
jxz203@psu.edu

Research Interests

  • Neoplasms
  • Colorectal Neoplasms
  • Smokers
  • Tobacco Products
  • Survival
  • Mothers
  • Smoking
  • Nicotine
  • Pregnancy
  • Proteins
  • Circulating Neoplastic Cells
  • Population

Clinical Trials

Accuracy of Contrast-Enhanced Ultrasound for hepatocellular carcinoma (HCC) post transcatheter arterial chemoembolization (TACE)
Observational Study to Determine the Differences in Molecular Characterization between Smokers vs. Non-smokers in Patients with Stage IV Bladder Cancer and their Correlation with Clinical Outcome
Tissue and Blood Collection from Patients with Suspected Lung Cancer

Recent Publications

2020

Zheng, H, Mineishi, S, Claxton, D, Zhu, J, Zhao, C, Jia, B, Ehmann, WC, Rybka, WB, Naik, S, Songdej, N, Drabick, JJ & Hohl, RJ 2020, 'A phase I clinical trial of avelumab in combination with decitabine as first line treatment of unfit patients with acute myeloid leukemia', American Journal of Hematology. https://doi.org/10.1002/ajh.26043
Soriano, CT, McGarrity, TJ, Zhu, J, Loloi, J, Peiffer, LP & Cooper, J 2020, 'An Electronic Questionnaire to Survey Colorectal Cancer Screening Status and Identify High-Risk Cohorts in Large Health Care Organizations', American Journal of Medical Quality. https://doi.org/10.1177/1062860620937236
Chen, KM, Sun, YW, Kawasawa, YI, Salzberg, AC, Zhu, J, Gowda, K, Aliaga, C, Amin, S, Atkins, H & El-Bayoumy, K 2020, 'Black raspberry inhibits oral tumors in mice treated with the tobacco smoke constituent dibenzo(def,p)chrysene via genetic and epigenetic alterations', Cancer Prevention Research, vol. 13, no. 4, pp. 357-365. https://doi.org/10.1158/1940-6207.CAPR-19-0496
Lin, W, Krebs, NM, Zhu, J, Foulds, J, Horn, K & Muscat, JE 2020, 'Comparison between gradual reduced nicotine content and usual nicotine content groups on subjective cigarette ratings in a randomized double-blind trial', International journal of environmental research and public health, vol. 17, no. 19, 7047, pp. 1-9. https://doi.org/10.3390/ijerph17197047
Pool, C, Ehret, C, Engle, L, Zhu, J & Wilson, MN 2020, 'Feasibility of same day surgery for pediatric second branchial cleft anomalies', International Journal of Pediatric Otorhinolaryngology, vol. 139, 110402. https://doi.org/10.1016/j.ijporl.2020.110402
Liu, J, Xu, C, Zhu, J, Sivik, J, Drabick, JJ & Mackley, HB 2020, 'Identifying the optimal fractionation schedules for improved response rates and survival in patients with metastatic melanoma treated with ipilimumab and radiotherapy', Current Cancer Therapy Reviews, vol. 16, no. 1, pp. 78-85. https://doi.org/10.2174/2542584601666180326111906

2019

Elcheva, I, Sneed, M, Frazee, S, Liu, Z, Zhu, J, Wood, T, Hendrickson, S, Oehler, C, Garcia, B & Spiegelman, VS 2019, 'A novel hiPSC-derived system for hematoendothelial and myeloid blood toxicity screens identifies compounds promoting and inhibiting endothelial-to-hematopoietic transition', Toxicology in Vitro, vol. 61, 104622. https://doi.org/10.1016/j.tiv.2019.104622
Zhu, J, Hussain, M, Joshi, A, Truica, CI, Nesterova, D, Collins, J, Saunders, EFH, Hayes, M, Drabick, JJ & Joshi, M 2020, 'Effect of creative writing on mood in patients with cancer', BMJ Supportive and Palliative Care, vol. 10, no. 1, pp. 64-67. https://doi.org/10.1136/bmjspcare-2018-001710
Lee, SY, Walter, V, Zhu, J, Salzberg, AC, Liu, DJ & Connor, JR 2019, 'Impact of HFE variants and sex in lung cancer', PloS one, vol. 14, no. 12, e0226821. https://doi.org/10.1371/journal.pone.0226821
Pu, JJ, Poulose, J, Malysz, J, Zhu, J, Fanburg-Smith, JC, Claxton, DF & Bayerl, MG 2019, 'Impact of ruxolitinib on myelofibrosis patients post allogeneic stem cell transplant—a pilot study', British Journal of Haematology, vol. 186, no. 5, pp. e130-e133. https://doi.org/10.1111/bjh.15967
Zhu, J, Nelson, K, Toth, J & Muscat, JE 2019, 'Nicotine dependence as an independent risk factor for atherosclerosis in the National Lung Screening Trial', BMC Public Health, vol. 19, no. 1, 103. https://doi.org/10.1186/s12889-019-6419-8
Sun, YW, Xu, H, Benitez, G, Chen, KM, Stanley, A, Stanley, B, Zhu, J, Thompson, H, Manni, A & El-Bayoumy, K 2019, 'Omega-3 Fatty Acids Responsive Proteins and Reduction in Breast Density in Obese Postmenopausal Women', Journal of Proteome Research, vol. 18, no. 9, pp. 3461-3469. https://doi.org/10.1021/acs.jproteome.9b00356
Bann, DV, Chaikhoutdinov, I, Zhu, J & Andrews, GA 2019, 'Satellite and In-Transit Metastatic Disease in Melanoma Skin Cancer: A Retrospective Review of Disease Presentation, Treatment, and Outcomes', Dermatologic Surgery, vol. 45, no. 3, pp. 371-380. https://doi.org/10.1097/DSS.0000000000001643
Barth, BM, Wang, W, Toran, PT, Fox, TE, Annageldiyev, C, Ondrasik, RM, Keasey, NR, Brown, TJ, Devine, VG, Sullivan, EC, Cote, AL, Papakotsi, V, Tan, SF, Shanmugavelandy, SS, Deering, TG, Needle, DB, Stern, ST, Zhu, J, Liao, J, Viny, AD, Feith, DJ, Levine, RL, Wang, HG, Loughran, TP, Sharma, A, Kester, M & Claxton, DF 2019, 'Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia', Blood Advances, vol. 3, no. 17, pp. 2598-2603. https://doi.org/10.1182/bloodadvances.2018021295

2018

Van De Louw, A, Desai, RJ, Zhu, J & Claxton, D 2018, 'Characteristics of early acute respiratory distress syndrome in newly diagnosed acute myeloid leukemia', Leukemia and Lymphoma, vol. 59, no. 10, pp. 2369-2376. https://doi.org/10.1080/10428194.2018.1435874
Chen, KM, Sun, YW, Cooper, T, Benitez, G, Aliaga, C, Zhu, J, Gowda, K, Amin, S & El-Bayoumy, K 2018, 'Comparative Tumorigenicity and DNA Damage Induced by Dibenzo[ def,p]chrysene and Its Metabolites in the Mouse Ovary', Chemical research in toxicology, vol. 31, no. 11, pp. 1111-1118. https://doi.org/10.1021/acs.chemrestox.8b00152
Joseph, S, Krebs, NM, Zhu, J, Wert, Y, Goel, R, Reilly, SM, Sun, D, Richie, JP, Nikiforov, I, Cheriyath, P & Muscat, JE 2018, 'Differences in nicotine dependence, smoke exposure and consumer characteristics between smokers of machine-injected roll-your-own cigarettes and factory-made cigarettes', Drug and alcohol dependence, vol. 187, pp. 109-115. https://doi.org/10.1016/j.drugalcdep.2018.01.039
Chen, KM, Guttenplan, JB, Sun, YW, Cooper, T, Shalaby, NAE, Kosinska, W, Benitez, G, Aliaga, C, Zhu, J, Liao, J, Gowda, K, Amin, S, Stoner, G & El-Bayoumy, K 2018, 'Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNAAdducts, Mutagenesis, and Tumorigenesis in the Mouse Oral Cavity', Cancer Prevention Research, vol. 11, no. 3, pp. 157-164. https://doi.org/10.1158/1940-6207.CAPR-17-0278
Pameijer, CR, Leung, A, Neves, RI & Zhu, J 2018, 'Indocyanine green and fluorescence lymphangiography for sentinel node identification in patients with melanoma', American Journal of Surgery, vol. 216, no. 3, pp. 558-561. https://doi.org/10.1016/j.amjsurg.2018.01.009
Zaorsky, N, Ahmed, AA, Zhu, J, Yoo, SK, Fuller, CD, Thomas, CR, Choi, M & Holliday, EB 2019, 'Industry Funding Is Correlated With Publication Productivity of US Academic Radiation Oncologists', Journal of the American College of Radiology, vol. 16, no. 2, pp. 244-251. https://doi.org/10.1016/j.jacr.2018.07.024
Chen, A, Krebs, NM, Zhu, J & Muscat, JE 2018, 'Nicotine metabolite ratio predicts smoking topography: The Pennsylvania Adult Smoking Study', Drug and alcohol dependence, vol. 190, pp. 89-93. https://doi.org/10.1016/j.drugalcdep.2018.06.003

2017

Allen, SI, Foulds, J, Pachas, GN, Veldheer, S, Cather, C, Azzouz, N, Hrabovsky, S, Hameed, A, Yingst, J, Hammett, E, Modesto, J, Krebs, NM, Zhu, J, Liao, J, Muscat, JE, Richie, J & Evins, AE 2017, 'A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol', BMC Public Health, vol. 17, no. 1, 100, pp. 1-13. https://doi.org/10.1186/s12889-016-3946-4
Felts, JL, Zhu, J, Han, B, Smith, SJ & Truica, CI 2017, 'An Analysis of Oncotype DX Recurrence Scores and Clinicopathologic Characteristics in Invasive Lobular Breast Cancer', Breast Journal, vol. 23, no. 6, pp. 677-686. https://doi.org/10.1111/tbj.12751
Lee, SY, Zhu, J, Salzberg, AC, Zhang, B, Liu, DJ, Muscat, JE, Langan, ST & Connor, JR 2017, 'Analysis of single nucleotide variants of HFE gene and association to survival in the Cancer Genome Atlas GBM data', PloS one, vol. 12, no. 3, e0174778. https://doi.org/10.1371/journal.pone.0174778
Kokolus, KM, Zhang, Y, Sivik, JM, Schmeck, C, Zhu, J, Repasky, EA, Drabick, JJ & Schell, TD 2018, 'Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in mice', OncoImmunology, vol. 7, no. 3, e1405205. https://doi.org/10.1080/2162402X.2017.1405205
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, J, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, JP & Muscat, JE 2017, 'Correction: Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial. [Trials. 18, (2017) (300)] DOI: 10.1186/s13063-017-2038-9', Trials, vol. 18, no. 1, 598. https://doi.org/10.1186/s13063-017-2356-y
Alexander, CP, Zhu, J, Paul, IM & Kjerulff, KH 2017, 'Fathers make a difference: positive relationships with mother and baby in relation to infant colic', Child: Care, Health and Development, vol. 43, no. 5, pp. 687-696. https://doi.org/10.1111/cch.12445
Sun, YW, Chen, KM, Kawasawa, YI, Salzberg, AC, Cooper, TK, Caruso, C, Aliaga, C, Zhu, J, Gowda, K, Amin, S & El-Bayoumy, K 2017, 'Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene', PloS one, vol. 12, no. 10, e0186873. https://doi.org/10.1371/journal.pone.0186873
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, J, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, JP & Muscat, JE 2017, 'Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial', Trials, vol. 18, no. 1, 300. https://doi.org/10.1186/s13063-017-2038-9
Chen, A, Krebs, NM, Zhu, J, Sun, D, Stennett, A & Muscat, JE 2017, 'Sex/Gender Differences in Cotinine Levels among Daily Smokers in the Pennsylvania Adult Smoking Study', Journal of Women's Health, vol. 26, no. 11, pp. 1222-1230. https://doi.org/10.1089/jwh.2016.6317
Small, J, Washburn, E, Millington, K, Zhu, J & Holder, SL 2017, 'The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors', Oncotarget, vol. 8, no. 56, pp. 95116-95134. https://doi.org/10.18632/oncotarget.19618

Clinical Trials Search


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