Researcher Profile

Researcher Profile

Junjia Zhu, MS, PhD

Junjia Zhu, MS, PhD

Assistant Professor, Department of Public Health Sciences
Division of Biostatistics and Bioinformatics
Scientific Program:Cancer Control
jxz203@psu.edu

Research Interests

  • Neoplasms
  • Therapeutics
  • Colorectal Neoplasms
  • Smoking
  • Pregnancy
  • Mothers
  • Tobacco Products
  • Survival
  • Nicotine
  • Circulating Neoplastic Cells
  • Population
  • Postpartum Period

Clinical Trials

Observational Study to Determine the Differences in Molecular Characterization between Smokers vs. Non-smokers in Patients with Stage IV Bladder Cancer and their Correlation with Clinical Outcome
Tissue and Blood Collection from Patients with Suspected Lung Cancer

Recent Publications

2019

Zhu, J, Hussain, M, Joshi, A, Truica, C, Nesterova, D, Collins, J, Saunders, EFH, Hayes, M, Drabick, J & Joshi, M 2019, 'Effect of creative writing on mood in patients with cancer' BMJ Supportive and Palliative Care. https://doi.org/10.1136/bmjspcare-2018-001710
Pu, JJ, Poulose, J, Malysz, J, Zhu, J, Fanburg-Smith, J, Claxton, D & Bayerl, M 2019, 'Impact of ruxolitinib on myelofibrosis patients post allogeneic stem cell transplant—a pilot study', British Journal of Haematology. https://doi.org/10.1111/bjh.15967
Zhu, J, Nelson, K, Toth, J & Muscat, J 2019, 'Nicotine dependence as an independent risk factor for atherosclerosis in the National Lung Screening Trial' BMC Public Health, vol. 19, no. 1, 103. https://doi.org/10.1186/s12889-019-6419-8

2018

Van De Louw, A, Desai, RJ, Zhu, J & Claxton, D 2018, 'Characteristics of early acute respiratory distress syndrome in newly diagnosed acute myeloid leukemia', Leukemia and Lymphoma, vol. 59, no. 10, pp. 2369-2376. https://doi.org/10.1080/10428194.2018.1435874
Chen, K-M, Sun, Y-W, Cooper, TK, Benitez, G, Aliaga, C, Zhu, J, Gowda, K, Amin, S & El-Bayoumy, K 2018, 'Comparative Tumorigenicity and DNA Damage Induced by Dibenzo[ def,p]chrysene and Its Metabolites in the Mouse Ovary' Chemical Research in Toxicology, vol. 31, no. 11, pp. 1111-1118. https://doi.org/10.1021/acs.chemrestox.8b00152
Joseph, S, Krebs, NM, Zhu, J, Wert, Y, Goel, R, Reilly, SM, Sun, D, Richie, J, Nikiforov, I, Cheriyath, P & Muscat, J 2018, 'Differences in nicotine dependence, smoke exposure and consumer characteristics between smokers of machine-injected roll-your-own cigarettes and factory-made cigarettes', Drug and Alcohol Dependence, vol. 187, pp. 109-115. https://doi.org/10.1016/j.drugalcdep.2018.01.039
Chen, K-M, Guttenplan, JB, Sun, Y-W, Cooper, T, Shalaby, NAE, Kosinska, W, Benitez, G, Aliaga, C, Zhu, J, Liao, JJ, Gowda, K, Amin, S, Stoner, G & El-Bayoumy, K 2018, 'Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNAAdducts, Mutagenesis, and Tumorigenesis in the Mouse Oral Cavity', Cancer Prevention Research, vol. 11, no. 3, pp. 157-164. https://doi.org/10.1158/1940-6207.CAPR-17-0278
Pameijer, CR, Leung, A, Neves, R & Zhu, J 2018, 'Indocyanine green and fluorescence lymphangiography for sentinel node identification in patients with melanoma', American Journal of Surgery, vol. 216, no. 3, pp. 558-561. https://doi.org/10.1016/j.amjsurg.2018.01.009
Zaorsky, N, Ahmed, AA, Zhu, J, Yoo, SK, Fuller, CD, Thomas, CR, Choi, M & Holliday, EB 2019, 'Industry Funding Is Correlated With Publication Productivity of US Academic Radiation Oncologists', Journal of the American College of Radiology, vol. 16, no. 2, pp. 244-251. https://doi.org/10.1016/j.jacr.2018.07.024
Chen, A, Krebs, NM, Zhu, J & Muscat, J 2018, 'Nicotine metabolite ratio predicts smoking topography: The Pennsylvania Adult Smoking Study', Drug and Alcohol Dependence, vol. 190, pp. 89-93. https://doi.org/10.1016/j.drugalcdep.2018.06.003

2017

Allen, SI, Foulds, J, Pachas, GN, Veldheer, S, Cather, C, Azzouz, N, Hrabovsky, S, Hameed, A, Yingst, J, Hammett, E, Modesto, J, Krebs, NM, Zhu, J, Liao, JJ, Muscat, J, Richie, J & Evins, AE 2017, 'A two-site, two-arm, 34-week, double-blind, parallel-group, randomized controlled trial of reduced nicotine cigarettes in smokers with mood and/or anxiety disorders: trial design and protocol', BMC Public Health, vol. 17, no. 1, pp. 1-13. https://doi.org/10.1186/s12889-016-3946-4
Felts, JL, Zhu, J, Han, B, Smith, JS & Truica, C 2017, 'An Analysis of Oncotype DX Recurrence Scores and Clinicopathologic Characteristics in Invasive Lobular Breast Cancer', Breast Journal, vol. 23, no. 6, pp. 677-686. https://doi.org/10.1111/tbj.12751
Lee, S, Zhu, J, Salzberg, AC, Zhang, B, Liu, D, Muscat, J, Langan, ST & Connor, J 2017, 'Analysis of single nucleotide variants of HFE gene and association to survival in the Cancer Genome Atlas GBM data', PloS one, vol. 12, no. 3, e0174778. https://doi.org/10.1371/journal.pone.0174778
Kokolus, KM, Zhang, Y, Sivik, JM, Schmeck, C, Zhu, J, Repasky, EA, Drabick, J & Schell, T 2018, 'Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in mice', OncoImmunology, vol. 7, no. 3, e1405205. https://doi.org/10.1080/2162402X.2017.1405205
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, JJ, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, J & Muscat, J 2017, 'Correction: Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial. [Trials. 18, (2017) (300)] DOI: 10.1186/s13063-017-2038-9' Trials, vol. 18, no. 1, 598. https://doi.org/10.1186/s13063-017-2356-y
Alexander, C, Zhu, J, Paul, I & Kjerulff, K 2017, 'Fathers make a difference: positive relationships with mother and baby in relation to infant colic', Child: Care, Health and Development, vol. 43, no. 5, pp. 687-696. https://doi.org/10.1111/cch.12445
Sun, Y-W, Chen, K-M, Imamura, Y, Salzberg, AC, Cooper, TK, Caruso, C, Aliaga, C, Zhu, J, Gowda, K, Amin, S & El-Bayoumy, K 2017, 'Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene', PloS one, vol. 12, no. 10, e0186873. https://doi.org/10.1371/journal.pone.0186873
Krebs, NM, Allen, SI, Veldheer, S, Martinez, DJ, Horn, K, Livelsberger, C, Modesto, J, Kuprewicz, R, Wilhelm, A, Hrabovsky, S, Kazi, A, Fazzi, A, Liao, JJ, Zhu, J, Wasserman, E, Reilly, SM, Reinhart, L, Trushin, N, Moyer, RE, Bascom, R, Foulds, J, Richie, J & Muscat, J 2017, 'Reduced nicotine content cigarettes in smokers of low socioeconomic status: Study protocol for a randomized control trial', Trials, vol. 18, no. 1, 300. https://doi.org/10.1186/s13063-017-2038-9
Chen, A, Krebs, NM, Zhu, J, Sun, D, Stennett, A & Muscat, J 2017, 'Sex/Gender Differences in Cotinine Levels among Daily Smokers in the Pennsylvania Adult Smoking Study', Journal of Women's Health, vol. 26, no. 11, pp. 1222-1230. https://doi.org/10.1089/jwh.2016.6317
Small, J, Washburn, E, Millington, K, Zhu, J & Holder, S 2017, 'The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors', Oncotarget, vol. 8, no. 56, pp. 95116-95134. https://doi.org/10.18632/oncotarget.19618

2016

Liu, Y, Zhu, J & Lin, DKJ 2016, 'A generalized likelihood ratio test for monitoring profile data' Paper presented at 12th International Workshop on Intelligent Statistical Quality Control, IWISQC 2016, Hamburg, Germany, 8/16/16 - 8/19/16, pp. 309-325.
Tan, SF, Liu, X, Fox, TE, Barth, BM, Sharma, A, Turner, SD, Awwad, A, Dewey, A, Doi, K, Spitzer, B, Shah, MV, Morad, SAF, Desai, D, Amin, S, Zhu, J, Liao, JJ, Yun, J, Kester, M, Claxton, D, Wang, H-G, Cabot, MC, Schuchman, EH, Levine, RL, Feith, DJ & Loughran, TP 2016, 'Acid ceramidase is upregulated in AML and represents a novel therapeutic target', Oncotarget, vol. 7, no. 50, pp. 83208-83222. https://doi.org/10.18632/oncotarget.13079
Malysz, J, Erdman, P, Klapper, J, Zhu, J, Creer, M & Bayerl, M 2016, 'Clinical Implications of CD30 Expression in Aggressive B-Cell Lymphomas', Clinical Lymphoma, Myeloma and Leukemia, vol. 16, no. 8, pp. 429-433. https://doi.org/10.1016/j.clml.2016.04.011
Krebs, NM, Chen, A, Zhu, J, Sun, D, Liao, JJ, Stennett, AL & Muscat, J 2016, 'Comparison of Puff Volume with Cigarettes per Day in Predicting Nicotine Uptake among Daily Smokers', American Journal of Epidemiology, vol. 184, no. 1, pp. 48-57. https://doi.org/10.1093/aje/kwv341
LaRosa, CL, Quach, KA, Koons, K, Kunselman, AR, Zhu, J, Thiboutot, DM & Zaenglein, AL 2016, 'Consumption of dairy in teenagers with and without acne', Journal of the American Academy of Dermatology, vol. 75, no. 2, pp. 318-322. https://doi.org/10.1016/j.jaad.2016.04.030
Malysz, J, Talamo, G, Zhu, J, Clarke, LE, Bayerl, M, Ali, L, Helm, K & Chung, C 2016, 'Cutaneous involvement in multiple myeloma (MM): A case series with clinicopathologic correlation', Journal of the American Academy of Dermatology, vol. 74, no. 5, pp. 878-884. https://doi.org/10.1016/j.jaad.2015.12.028
Zheng, H, Liu, X, Zhang, J, Rice, SJ, Wagman, M, Kong, Y, Zhu, L, Zhu, J, Joshi, M & Belani, C 2016, 'Expression of PD-1 on CD4+ T cells in peripheral blood associates with poor clinical outcome in non-small cell lung cancer', Oncotarget, vol. 7, no. 35, pp. 56233-56240. https://doi.org/10.18632/oncotarget.9316
Hackman, N, Alligood-Percoco, N, Martin, A, Zhu, J & Kjerulff, K 2016, 'Reduced breastfeeding rates in firstborn late preterm and early term infants', Breastfeeding Medicine, vol. 11, no. 3, pp. 119-125. https://doi.org/10.1089/bfm.2015.0122
Joshi, M, Vasekar, M, Grivas, P, Emamekhoo, H, Hsu, JA, Miller, VA, Stephens, PJ, Ali, SM, Ross, JS, Zhu, J, Warrick, J, Drabick, J, Holder, S, Kaag, MG, Li, M & Pal, SK 2016, 'Relationship of smoking status to genomic profile, chemotherapy response and clinical outcome in patients with advanced urothelial carcinoma', Oncotarget, vol. 7, no. 32, pp. 52442-52449. https://doi.org/10.18632/oncotarget.9449
Chetlen, A, Brown, KL, King, SH, Kasales, C, Schetter, S, Mack, J & Zhu, J 2016, 'Scatter radiation dose from digital screening mammography measured in a representative patient population', American Journal of Roentgenology, vol. 206, no. 2, pp. 359-365. https://doi.org/10.2214/AJR.15.14921
McCall-Hosenfeld, J, Phiri, K, Schaefer, E, Zhu, J & Kjerulff, K 2016, 'Trajectories of Depressive Symptoms Throughout the Peri-and Postpartum Period: Results from the First Baby Study', Journal of Women's Health, vol. 25, no. 11, pp. 1112-1121. https://doi.org/10.1089/jwh.2015.5310

2015

Kuder, CH, Weivoda, MM, Zhang, Y, Zhu, J, Neighbors, J, Wiemer, DF & Hohl, R 2015, '3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines' Lipids, vol. 50, no. 12, pp. 1195-1207. https://doi.org/10.1007/s11745-015-4083-z
Blake, N, Zhu, J, Hernandez, G & Juliano, P 2015, 'A retrospective review of diagnostic testing for onychomycosis of the foot', Journal of the American Podiatric Medical Association, vol. 105, no. 6, pp. 503-508. https://doi.org/10.7547/14-063.1
Kaifi, JT, Kunkel, M, Das, A, Harouaka, RA, Dicker, DT, Li, G, Zhu, J, Clawson, G, Yang, Z, Reed, MF, Gusani, NJ, Kimchi, ET, Staveley-O’Carroll, KF, Zheng, S & El-Deiry, WS 2015, 'Circulating tumor cell isolation during resection of colorectal cancer lung and liver metastases: A prospective trial with different detection techniques', Cancer Biology and Therapy, vol. 16, no. 5, pp. 699-708. https://doi.org/10.1080/15384047.2015.1030556
Kaifi, JT, Kunkel, M, Dicker, DT, Joude, J, Allen, JE, Das, A, Zhu, J, Yang, Z, Sarwani, N, Li, G, Staveley-O’Carroll, KF & El-Deiry, WS 2015, 'Circulating tumor cell levels are elevated in colorectal cancer patients with high tumor burden in the liver' Cancer Biology and Therapy, vol. 16, no. 5, pp. 690-698. https://doi.org/10.1080/15384047.2015.1026508
Das, A, Kunkel, M, Joudeh, J, Dicker, DT, Scicchitano, A, Allen, JE, Sarwani, N, Yang, Z, Kaifi, J, Zhu, J, Liao, JJ & El-Deiry, WS 2015, 'Clinico-pathological correlation of serial measurement of circulating tumor cells in 24 metastatic colorectal cancer patients receiving chemotherapy reveals interpatient heterogeneity correlated with CEA levels but independent of KRAS and BRAF mutation' Cancer Biology and Therapy, vol. 16, no. 5, pp. 709-713. https://doi.org/10.1080/15384047.2015.1030555
Talamo, G, Dimaio, C, Abbi, KKS, Pandey, MK, Malysz, J, Creer, M, Zhu, J, Mir, MA & Varlotto, JM 2015, 'Current role of radiation therapy for multiple myeloma' Frontiers in Oncology, vol. 5, no. FEB, 40. https://doi.org/10.3389/fonc.2015.00040
Holder, S, Drabick, J, Zhu, J & Joshi, M 2015, 'Dexamethasone may be the most efficacious corticosteroid for use as monotherapy in castration-resistant prostate cancer' Cancer Biology and Therapy, vol. 16, no. 2, pp. 207-209. https://doi.org/10.1080/15384047.2014.1002687
Bicking Kinsey, C, Baptiste-Roberts, K, Zhu, J & Kjerulff, K 2015, 'Effect of Multiple Previous Miscarriages on Health Behaviors and Health Care Utilization During Subsequent Pregnancy' Women's Health Issues, vol. 25, no. 2, pp. 155-161. https://doi.org/10.1016/j.whi.2014.11.008
Talamo, G, Mir, MA, Pandey, MK, Zhu, J, Creer, M & Malysz, J 2015, 'Estimation of daily proteinuria in patients with amyloidosis by using the protein-to-creatinine ratio in random urine samples' Rare Tumors, vol. 7, no. 1, 5686, pp. 16-19. https://doi.org/10.4081/rt.2015.5686
Lee, S, Slagle-Webb, B, Sheehan, JM, Zhu, J, Muscat, J, Glantz, M & Connor, J 2015, 'HFE polymorphisms affect survival of brain tumor patients' Journal of neuro-oncology, vol. 122, no. 1, pp. 97-104. https://doi.org/10.1007/s11060-014-1681-1
Haakenson, JK, Khokhlatchev, AV, Choi, YJ, Linton, SS, Zhang, P, Zaki, PM, Fu, C, Cooper, T, Manni, A, Zhu, J, Fox, TE, Dong, C & Kester, M 2015, 'Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells' Journal of Biological Chemistry, vol. 290, no. 13, pp. 8632-8643. https://doi.org/10.1074/jbc.M114.609677
Rice, SJ, Liu, X, Miller, B, Joshi, M, Zhu, J, Caruso, C, Gilbert, C, Toth, J, Reed, MF, Rassaei, N, Das, A, Barochia, A, El-Bayoumy, K & Belani, C 2015, 'Proteomic profiling of human plasma identifies apolipoprotein E as being associated with smoking and a marker for squamous metaplasia of the lung' Proteomics, vol. 15, no. 18, pp. 3267-3277. https://doi.org/10.1002/pmic.201500029
Phelan, AL, DiBenedetto, MR, Paul, I, Zhu, J & Kjerulff, K 2015, 'Psychosocial Stress During First Pregnancy Predicts Infant Health Outcomes in the First Postnatal Year', Maternal and child health journal, vol. 19, no. 12, pp. 2587-2597. https://doi.org/10.1007/s10995-015-1777-z
Bhimanapati, GR, Lin, Z, Meunier, V, Jung, Y, Cha, J, Das, S, Xiao, D, Son, Y, Strano, MS, Cooper, VR, Liang, L, Louie, SG, Ringe, E, Zhou, W, Kim, SS, Naik, RR, Sumpter, BG, Terrones, H, Xia, F, Wang, Y, Zhu, J, Akinwande, D, Alem, N, Schuller, JA, Schaak, RE, Terrones Maldonado, M & Robinson, JA 2015, 'Recent Advances in Two-Dimensional Materials beyond Graphene', ACS Nano, vol. 9, no. 12, pp. 11509-11539. https://doi.org/10.1021/acsnano.5b05556
Veldheer, S, Yingst, J, Zhu, J & Foulds, J 2015, 'Ten-year weight gain in smokers who quit, smokers who continued smoking and never smokers in the United States, NHANES 2003-2012' International Journal of Obesity, vol. 39, no. 12, pp. 1727-1732. https://doi.org/10.1038/ijo.2015.127
Manahan, E, Wang, L, Chen, S, Dickson-Witmer, D, Zhu, J, Holmes, D & Kass, R 2015, 'What is a Breast Surgeon Worth? A Salary Survey of the American Society of Breast Surgeons', Annals of Surgical Oncology, vol. 22, no. 10, pp. 3257-3263. https://doi.org/10.1245/s10434-015-4720-z

Clinical Trials Search


Children (age < 18 years)
Adults (age >= 18 years)