Jian Yang, PhD - Penn State Cancer Institute
Researcher Profile
Jian Yang, PhD
Professor, Biomedical Engineering
Center for Neural Engineering
Center for Neural Engineering
Scientific Program:Next-Generation Therapies
Research Interests
- Citric Acid
- Polymers
- Tissue Engineering
- Elastomers
- Biocompatible Materials
- Nanoparticles
- Pharmaceutical Preparations
- Bone and Bones
- In Vitro Techniques
- Blood Vessels
- Polyesters
- Durapatite
Recent Publications
2023
Wu, K, Fu, M, Zhao, Y, Gerhard, E, Li, Y, Yang, J & Guo, J 2023, 'Anti-oxidant anti-inflammatory and antibacterial tannin-crosslinked citrate-based mussel-inspired bioadhesives facilitate scarless wound healing', Bioactive Materials, vol. 20, pp. 93-110. https://doi.org/10.1016/j.bioactmat.2022.05.017
Zhu, J, Zhou, H, Gerhard, EM, Zhang, S, Parra Rodríguez, FI, Pan, T, Yang, H, Lin, Y, Yang, J & Cheng, H 2023, 'Smart bioadhesives for wound healing and closure', Bioactive Materials, vol. 19, pp. 360-375. https://doi.org/10.1016/j.bioactmat.2022.04.020
2022
Pandey, NK, Xiong, W, Wang, L, Chen, W, Bui, B, Yang, J, Amador, E, Chen, M, Xing, C, Athavale, AA, Hao, Y, Feizi, W & Lumata, L 2022, 'Aggregation-induced emission luminogens for highly effective microwave dynamic therapy', Bioactive Materials, vol. 7, pp. 112-125. https://doi.org/10.1016/j.bioactmat.2021.05.031
Perera, K, Nguyen, DX, Wang, D, Kuriakose, AE, Yang, J, Nguyen, KT & Menon, JU 2022, 'Biodegradable and Inherently Fluorescent pH-Responsive Nanoparticles for Cancer Drug Delivery', Pharmaceutical Research, vol. 39, no. 11, pp. 2729-2743. https://doi.org/10.1007/s11095-022-03317-8
Wang, D, Xia, T, Wang, Y, Chen, Y, Zhang, C, Murray, W, Schultz, AT, Liu, Z & Yang, J 2022, 'Citrate-based fluorometric sensor for multi-halide sensing', Smart Materials in Medicine, vol. 3, pp. 374-381. https://doi.org/10.1016/j.smaim.2022.05.001
Tan, X, Gerhard, E, Wang, Y, Tran, RT, Xu, H, Yan, S, Rizk, EB, Armstrong, AD, Zhou, Y, Du, J, Bai, X & Yang, J 2022, 'Development of Biodegradable Osteopromotive Citrate-Based Bone Putty', Small, vol. 18, no. 36, 2203003. https://doi.org/10.1002/smll.202203003
2021
Tang, S, Chi, K, Xu, H, Yong, Q, Yang, J & Catchmark, JM 2021, 'A covalently cross-linked hyaluronic acid/bacterial cellulose composite hydrogel for potential biological applications', Carbohydrate Polymers, vol. 252, 117123. https://doi.org/10.1016/j.carbpol.2020.117123
Zhu, J, Liu, S, Hu, Z, Zhang, X, Yi, N, Tang, K, Dexheimer, MG, Lian, X, Wang, Q, Yang, J, Gray, J & Cheng, H 2021, 'Laser-induced graphene non-enzymatic glucose sensors for on-body measurements', Biosensors and Bioelectronics, vol. 193, 113606. https://doi.org/10.1016/j.bios.2021.113606
Wang, D, Kuzma, ML, Tan, X, He, TC, Dong, C, Liu, Z & Yang, J 2021, 'Phototherapy and optical waveguides for the treatment of infection', Advanced Drug Delivery Reviews, vol. 179, 114036. https://doi.org/10.1016/j.addr.2021.114036
Siddiqui, Z, Sarkar, B, Kim, KK, Kumar, A, Paul, R, Mahajan, A, Grasman, JM, Yang, J & Kumar, VA 2021, 'Self-assembling peptide hydrogels facilitate vascularization in two-component scaffolds', Chemical Engineering Journal, vol. 422, 130145. https://doi.org/10.1016/j.cej.2021.130145
Zhu, J, Hu, Z, Song, C, Yi, N, Yu, Z, Liu, Z, Liu, S, Wang, M, Dexheimer, MG, Yang, J & Cheng, H 2021, 'Stretchable wideband dipole antennas and rectennas for RF energy harvesting', Materials Today Physics, vol. 18, 100377. https://doi.org/10.1016/j.mtphys.2021.100377
Zheng, M, Guo, J, Li, Q, Yang, J, Han, Y, Yang, H, Yu, M, Zhong, L, Lu, D, Li, L & Sun, L 2021, 'Syntheses and characterization of anti-thrombotic and anti-oxidative Gastrodin-modified polyurethane for vascular tissue engineering', Bioactive Materials, vol. 6, no. 2, pp. 404-419. https://doi.org/10.1016/j.bioactmat.2020.08.008
Gonsalves, A, Tambe, P, Le, D, Thakore, D, Wadajkar, AS, Yang, J, Nguyen, KT & Menon, JU 2021, 'Synthesis and characterization of a novel pH-responsive drug-releasing nanocomposite hydrogel for skin cancer therapy and wound healing', Journal of Materials Chemistry B, vol. 9, no. 46, pp. 9533-9546. https://doi.org/10.1039/d1tb01934a
2020
Wei, Q, Shi, X, Zhao, T, Cai, P, Chen, T, Zhang, Y, Huang, C, Yang, J, Chen, X & Zhang, S 2020, 'Actin-ring segment switching drives nonadhesive gap closure', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 52, pp. 33263-33271. https://doi.org/10.1073/PNAS.2010960117
Kuzma, M, Gerhard, E, Shan, D & Yang, J 2020, Advances in bioresorbable electronics and uses in biomedical sensing. in Interfacing Bioelectronics and Biomedical Sensing. Springer International Publishing, pp. 29-72. https://doi.org/10.1007/978-3-030-34467-2_2
Guo, J, Tian, X, Xie, D, Rahn, K, Gerhard, E, Kuzma, ML, Zhou, D, Dong, C, Bai, X, Lu, Z & Yang, J 2020, 'Citrate-Based Tannin-Bridged Bone Composites for Lumbar Fusion', Advanced Functional Materials, vol. 30, no. 27, 2002438. https://doi.org/10.1002/adfm.202002438
Li, Q, Li, L, Yu, M, Zheng, M, Li, Y, Yang, J, Dai, M, Zhong, L, Sun, L & Lu, D 2020, 'Elastomeric polyurethane porous film functionalized with gastrodin for peripheral nerve regeneration', Journal of Biomedical Materials Research - Part A, vol. 108, no. 8, pp. 1713-1725. https://doi.org/10.1002/jbm.a.36937
Kim, GB, Aragon-Sanabria, V, Randolph, L, Jiang, H, Reynolds, JA, Webb, BS, Madhankumar, A, Lian, X, Connor, JR, Yang, J & Dong, C 2020, 'High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma', Bioactive Materials, vol. 5, no. 3, pp. 624-635. https://doi.org/10.1016/j.bioactmat.2020.04.011
Lu, X, Shi, S, Li, H, Gerhard, E, Lu, Z, Tan, X, Li, W, Rahn, KM, Xie, D, Xu, G, Zou, F, Bai, X, Guo, J & Yang, J 2020, 'Magnesium oxide-crosslinked low-swelling citrate-based mussel-inspired tissue adhesives', Biomaterials, vol. 232, 119719. https://doi.org/10.1016/j.biomaterials.2019.119719
Pandey, N, Menon, JU, Takahashi, M, Hsieh, JT, Yang, J, Nguyen, KT & Wadajkar, AS 2020, 'Thermo-responsive fluorescent nanoparticles for multimodal imaging and treatment of cancers', Nanotheranostics, vol. 4, no. 1, pp. 1-13. https://doi.org/10.7150/ntno.39810
2019
Ma, C, Kuzma, ML, Bai, X & Yang, J 2019, 'Biomaterial-Based Metabolic Regulation in Regenerative Engineering', Advanced Science, vol. 6, no. 19, 1900819. https://doi.org/10.1002/advs.201900819
Kuriakose, AE, Pandey, N, Shan, D, Banerjee, S, Yang, J & Nguyen, KT 2019, 'Characterization of Photoluminescent Polylactone-Based Nanoparticles for Their Applications in Cardiovascular Diseases', Frontiers in Bioengineering and Biotechnology, vol. 7, 353. https://doi.org/10.3389/fbioe.2019.00353
Wang, H, Zhang, H, Sun, Q, Yang, J, Zeng, C, Ding, C, Cai, D, Liu, A & Bai, X 2019, 'Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression', Journal of Cellular Physiology, vol. 234, no. 3, pp. 2730-2740. https://doi.org/10.1002/jcp.27088
He, Y, Li, Q, Ma, C, Xie, D, Li, L, Zhao, Y, Shan, D, Chomos, SK, Dong, C, Tierney, JW, Sun, L, Lu, D, Gui, L & Yang, J 2019, 'Development of osteopromotive poly (octamethylene citrate glycerophosphate) for enhanced bone regeneration', Acta Biomaterialia, vol. 93, pp. 180-191. https://doi.org/10.1016/j.actbio.2019.03.050
Tarafder, S, Gulko, J, Kim, D, Sim, KH, Gutman, S, Yang, J, Cook, JL & Lee, CH 2019, 'Effect of dose and release rate of CTGF and TGFβ3 on avascular meniscus healing', Journal of Orthopaedic Research, vol. 37, no. 7, pp. 1555-1562. https://doi.org/10.1002/jor.24287
Shan, D, Ma, C & Yang, J 2019, 'Enabling biodegradable functional biomaterials for the management of neurological disorders', Advanced Drug Delivery Reviews, vol. 148, pp. 219-238. https://doi.org/10.1016/j.addr.2019.06.004
Zou, W, Lai, M, Zhang, Y, Zheng, L, Xing, Z, Li, T, Zou, Z, Song, Q, Zhao, X, Xia, L, Yang, J, Liu, A, Zhang, H, Cui, ZK, Jiang, Y & Bai, X 2019, 'Exosome Release Is Regulated by mTORC1', Advanced Science, vol. 6, no. 3, 1801313. https://doi.org/10.1002/advs.201801313
Yang, J & Kim, G 2019, Local delivery of epigenetically stimulating folic acid for peripheral nerve regeneration. in Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, Society for Biomaterials, 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence, Seattle, United States, 4/3/19.
Iyer, R, Kuriakose, AE, Yaman, S, Su, LC, Shan, D, Yang, J, Liao, J, Tang, L, Banerjee, S, Xu, H & Nguyen, KT 2019, 'Nanoparticle eluting-angioplasty balloons to treat cardiovascular diseases', International Journal of Pharmaceutics, vol. 554, pp. 212-223. https://doi.org/10.1016/j.ijpharm.2018.11.011
Liu, W, Wang, Z, Yang, J, Wang, Y, Li, K, Huang, B, Yan, B, Wang, T, Li, M, Zou, Z, Yang, J, Xiao, G, Cui, ZK, Liu, A & Bai, X 2019, 'Osteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice', Open biology, vol. 9, no. 5, 180262. https://doi.org/10.1098/rsob.180262