Researcher Profile

Researcher Profile

Jairam K.P. Vanamala, PhD

Jairam K.P. Vanamala, PhD

Associate Professor, Food Science
Scientific Program:Cancer Control

Research Interests

  • Colonic Neoplasms
  • Apoptosis
  • Neoplastic Stem Cells
  • Colon
  • Neoplasms
  • Diet
  • Carcinogenesis
  • Solanum tuberosum
  • Fruit
  • Citrus paradisi
  • Obesity
  • Anthocyanins

Recent Publications


Sidorov, E, Sanghera, DK & Vanamala, JKP 2019, 'Biomarker for ischemic stroke using metabolome: A clinician perspective', Journal of Stroke, vol. 21, no. 1, pp. 31-41.
Vanamala, JKP 2019, 'Potatoes for Targeting Colon Cancer Stem Cells', American Journal of Potato Research, vol. 96, no. 2, pp. 177-182.


Shondelmyer, K, Knight, R, Sanivarapu, A, Ogino, S & Vanamala, JKP 2018, 'Ancient Thali diet: Gut microbiota, immunity, and health', Yale Journal of Biology and Medicine, vol. 91, no. 2, pp. 177-184.
Ganesan, K, Chung, SK, Vanamala, JKP & Xu, B 2018, 'Causal relationship between diet-induced gut microbiota changes and diabetes: A novel strategy to transplant Faecalibacterium prausnitzii in preventing diabetes', International journal of molecular sciences, vol. 19, no. 12, 3720.
Lee, D, Swan, CK, Suskind, D, Wahbeh, G, Vanamala, JKP, Baldassano, RN, Leonard, MB & Lampe, JW 2018, 'Children with Crohn’s Disease Frequently Consume Select Food Additives', Digestive Diseases and Sciences, vol. 63, no. 10, pp. 2722-2728.
Tofighi, M, Guo, T, Vanamala, JKP & Monga, V 2018, Deep networks with shape priors for nucleus detection. in 2018 IEEE International Conference on Image Processing, ICIP 2018 - Proceedings., 8451797, Proceedings - International Conference on Image Processing, ICIP, IEEE Computer Society, pp. 719-723, 25th IEEE International Conference on Image Processing, ICIP 2018, Athens, Greece, 10/7/18.
Arya, R, Farook, VS, Fowler, SP, Puppala, S, Chittoor, G, Resendez, RG, Mummidi, S, Vanamala, JKP, Almasy, L, Curran, JE, Comuzzie, AG, Lehman, DM, Jenkinson, CP, Lynch, JL, DeFronzo, RA, Blangero, J, Hale, D, Duggirala, R & Diego, VP 2018, 'Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents' Genetic Epidemiology, vol. 42, no. 4, pp. 378-393.
Vanamala, JKP, Massey, AR, Pinnamaneni, SR, Reddivari, L & Reardon, KF 2018, 'Grain and sweet sorghum (Sorghum bicolor L. Moench) serves as a novel source of bioactive compounds for human health', Critical reviews in food science and nutrition, vol. 58, no. 17, pp. 2867-2881.


Sido, A, Radhakrishnan, S, Kim, SW, Eriksson, E, Shen, F, Li, Q, Bhat, V, Reddivari, L & Vanamala, JKP 2017, 'A food-based approach that targets interleukin-6, a key regulator of chronic intestinal inflammation and colon carcinogenesis', Journal of Nutritional Biochemistry, vol. 43, pp. 11-17.
Indugu, N, Vecchiarelli, B, Baker, LD, Ferguson, JD, Vanamala, JKP & Pitta, DW 2017, 'Comparison of rumen bacterial communities in dairy herds of different production', BMC Microbiology, vol. 17, no. 1, 190.
Vanamala, JKP 2017, 'Food systems approach to cancer prevention', Critical Reviews in Food Science and Nutrition, vol. 57, no. 12, pp. 2573-2588.
Farook, VS, Reddivari, L, Mummidi, S, Puppala, S, Arya, R, Lopez-Alvarenga, JC, Fowler, SP, Chittoor, G, Resendez, RG, Kumar, BM, Comuzzie, AG, Curran, JE, Lehman, DM, Jenkinson, CP, Lynch, JL, DeFronzo, RA, Blangero, J, Hale, D, Duggirala, R & Vanamala, JKP 2017, 'Genetics of serum carotenoid concentrations and their correlation with obesity-related traits in Mexican American children', American Journal of Clinical Nutrition, vol. 106, no. 1, pp. 52-58.
Reddivari, L, Sapkota, BR, Rudraraju, A, Liang, Y, Aston, C, Sidorov, E, Vanamala, JKP & Sanghera, DK 2017, 'Metabolite signatures of diabetes with cardiovascular disease: a pilot investigation' Metabolomics, vol. 13, no. 12, 154.
Charepalli, V, Reddivari, L, Radhakrishnan, S, Eriksson, E, Xiao, X, Kim, SW, Shen, F, Kumar, MV, Li, Q, Bhat, VB, Knight, R & Vanamala, JKP 2017, 'Pigs, unlike mice, have two distinct colonic stem cell populations similar to humans that respond to high-calorie diet prior to insulin resistance', Cancer Prevention Research, vol. 10, no. 8, pp. 442-450.
Bitzer, ZT, Wopperer, AL, Chrisfield, BJ, Tao, L, Cooper, T, Vanamala, JKP, Elias, R, Hayes, JE & Lambert, JD 2017, 'Soy protein concentrate mitigates markers of colonic inflammation and loss of gut barrier function in vitro and in vivo', Journal of Nutritional Biochemistry, vol. 40, pp. 201-208.


Yeoh, BS, Saha, P, Singh, V, Xiao, X, Ying, Y, Vanamala, JKP, Kennett, MJ, Harvatine, KJ, Joe, B & Kumar, MV 2016, 'Deficiency of stearoyl-CoA desaturase-1 aggravates colitogenic potential of adoptively transferred effector T cells' American Journal of Physiology - Gastrointestinal and Liver Physiology, vol. 311, no. 4, pp. G713-G723.
Charepalli, V, Reddivari, L, Vadde, R, Walia, S, Radhakrishnan, S & Vanamala, JKP 2016, 'Eugenia jambolana (Java plum) fruit extract exhibits anti-cancer activity against early stage human HCT-116 colon cancer cells and colon cancer stem cells', Cancers, vol. 8, no. 3, 29.
Reddivari, L, Charepalli, V, Radhakrishnan, S, Vadde, R, Elias, R, Lambert, JD & Vanamala, JKP 2016, 'Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis', BMC Complementary and Alternative Medicine, vol. 16, no. 1, 278.
Vadde, R, Radhakrishnan, S, Eranda Karunathilake Kurundu, H, Reddivari, L & Vanamala, JKP 2016, 'Indian gooseberry (Emblica officinalis Gaertn.) suppresses cell proliferation and induces apoptosis in human colon cancer stem cells independent of p53 status via suppression of c-Myc and cyclin D1', Journal of Functional Foods, vol. 25, pp. 267-278.
Dain, A, Repossi, G, Diaz-Gerevini, GT, Vanamala, JKP, Das, UN & Eynard, AR 2016, 'Long chain polyunsaturated fatty acids (LCPUFAs) and nordihydroguaiaretic acid (NDGA) modulate metabolic and inflammatory markers in a spontaneous type 2 diabetes mellitus model (Stillman Salgado rats)', Lipids in Health and Disease, vol. 15, no. 1, 205.
Massey, AR, Reddivari, L, Radhakrishnan, S, Charepalli, V, Kurundu Hewage, EK, Ramakrishna, V & Vanamala, JKP 2016, 'Pro-apoptotic activity against cancer stem cells differs between different parts of sweet sorghum', Journal of Functional Foods, vol. 23, pp. 601-613.


Charepalli, V, Reddivari, L, Radhakrishnan, S, Vadde, R, Agarwal, R & Vanamala, JKP 2015, 'Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells', Journal of Nutritional Biochemistry, vol. 26, no. 12, pp. 1641-1649.
Vanamala, JKP, Knight, R & Spector, TD 2015, 'Can Your Microbiome Tell You What to Eat?', Cell Metabolism, vol. 22, no. 6, pp. 960-961.
Guard, BC, Barr, JW, Reddivari, L, Klemashevich, C, Jayaraman, A, Steiner, JM, Vanamala, JKP & Suchodolski, JS 2015, 'Characterization of microbial dysbiosis and metabolomic changes in dogs with acute diarrhea', PLoS One, vol. 10, no. 5, e0127259.
Howard, KM, Jati Kusuma, R, Baier, SR, Friemel, T, Markham, L, Vanamala, JKP & Zempleni, J 2015, 'Loss of miRNAs during processing and storage of cow's (Bos taurus) milk', Journal of agricultural and food chemistry, vol. 63, no. 2, pp. 588-592.
Farook, VS, Reddivari, L, Chittoor, G, Puppala, S, Arya, R, Fowler, SP, Hunt, KJ, Curran, JE, Comuzzie, AG, Lehman, DM, Jenkinson, CP, Lynch, JL, Defronzo, RA, Blangero, J, Hale, D, Duggirala, R & Vanamala, JKP 2015, 'Metabolites as novel biomarkers for childhood obesity-related traits in Mexican-American children', Pediatric Obesity, vol. 10, no. 4, pp. 320-327.
Vadde, R, Radhakrishnan, S, Reddivari, L & Vanamala, JKP 2015, 'Triphala Extract Suppresses Proliferation and Induces Apoptosis in Human Colon Cancer Stem Cells via Suppressing c-Myc/Cyclin D1 and Elevation of Bax/Bcl-2 Ratio', BioMed Research International, vol. 2015, 649263.

Clinical Trials Search

Children (age < 18 years)
Adults (age >= 18 years)