Jacek Krzeminski, PhD
The ongoing projects in Dr. Jacek Krzeminski's laboratory are closely related to research on several aspects of chemical carcinogenesis as well as chemoprevention and drug discovery.
The lab is involved in structure elucidation and syntheses in the areas of polyaromatic hydrocarbons (PAHs), nitro-PAHs, nitrosoamines and their metabolites.
Among Dr. Krzeminski's interests are also structurally modified/ adducted oligonucleotides and nucleoside analogues of potential anticancer activity. Other projects include structure-based design approaches to the optimization of leads/small molecules for drug-like properties introduction.
- Epoxy Compounds
- DNA Adducts
- Human Mammary Glands
- Environmental Pollutants
- DNA Repair