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Researcher Profile

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Jane R. Schubart, MBA, MS, PhD

Jane R. Schubart, MBA, MS, PhD

Associate Professor, Department of Surgery
Division of Outcomes, Research and Quality
Associate Professor, Department of Medicine
Associate Professor, Department of Public Health Sciences
Scientific Program:Cancer Control
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Research Interests

Dr. Jane Schubart’s research interests focus on the investigation of health outcomes after surgery. Dr. Schubart is especially interested in complex or chronic illness and, since 2015, has worked on worked on research projects related to the heritable disorders of connective tissue, including the Ehlers-Danlos Syndromes. She has published a number of manuscripts related to recent work utilizing a data repository resulting from the National Institute on Aging (NIA) cohort study “Clinical and Molecular Manifestations of Heritable Disorders of Connective Tissue”, 2001-2013.

Funding for her work has come from NIH, Patient Centered Outcomes Research Institute (PCORI), American Cancer Society, Penn State Clinical and Translational Science Institute, Penn State College of Medicine's Grace Woodward Grant, University of Indiana School of Medicine, Bruhn-Morris Family Foundation, American Society of Breast Surgeons, American Spinal Injury Association, Paralyzed Veterans Association, Anthem Blue Cross Blue Shield of Virginia, National Board of Medical Examiners, and various philanthropic sources. 

  • Advance Care Planning
  • Health
  • Ehlers-Danlos Syndrome
  • Tonsillectomy
  • Child
  • Neoplasms
  • Hemorrhage
  • Prescriptions
  • Learning
  • Population
  • Decision Making
  • Pediatrics

Recent Publications


Doolan, BJ, Lavallee, ME, Hausser, I, Schubart, JR, Michael Pope, F, Seneviratne, SL, Winship, IM & Burrows, NP 2023, 'Extracutaneous features and complications of the Ehlers-Danlos syndromes: A systematic review', Frontiers in Medicine, vol. 10, 1053466.


Schubart, JR, Mills, SE, Schaefer, EW, Bascom, R & Francomano, CA 2022, 'Longitudinal analysis of symptoms in the Ehlers-Danlos syndromes', American Journal of Medical Genetics, Part A, vol. 188, no. 4, pp. 1204-1213.
Dhingra, R, Hakim, A, Bascom, R, Francomano, CA & Schubart, JR 2023, 'Prescription Claims for Immunomodulator and Antiinflammatory Drugs Among Persons With Ehlers-Danlos Syndromes', Arthritis Care and Research, vol. 75, no. 5, pp. 1183-1188.


Bascom, R, Dhingra, R, Francomano, CA & Schubart, JR 2021, 'A case–control study of respiratory medication and co-occurring gastrointestinal prescription burden among persons with Ehlers–Danlos syndromes', American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, vol. 187, no. 4, pp. 549-560.
Dhingra, R, Bascom, R, Thompson, E, Francomano, CA & Schubart, JR 2021, 'Gastrointestinal medication burden among persons with the Ehlers-Danlos syndromes', Neurogastroenterology and Motility, vol. 33, no. 7, e14077.
Schubart, JR, Bascom, R, Francomano, CA, Bloom, L & Hakim, AJ 2021, 'Initial description and evaluation of EDS ECHO: An international effort to improve care for people with the Ehlers-Danlos syndromes and hypermobility spectrum disorders', American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, vol. 187, no. 4, pp. 609-615.
Schubart, JR, Eliassen, AH, Schilling, A & Goldenberg, D 2021, 'Reproductive Factors and Risk of Thyroid Cancer in Women: An Analysis in the Nurses’ Health Study II', Women's Health Issues, vol. 31, no. 5, pp. 494-502.
Bloom, L, Schubart, J, Bascom, R, Hakim, A & Francomano, CA 2021, 'The power of patient-led global collaboration', American Journal of Medical Genetics, Part C: Seminars in Medical Genetics, vol. 187, no. 4, pp. 425-428.


Toth, S, Flohr, TR, Schubart, J, Knehans, A, Castello, MC & Aziz, F 2020, 'A meta-analysis and systematic review of venous thromboembolism prophylaxis in patients undergoing vascular surgery procedures', Journal of Vascular Surgery: Venous and Lymphatic Disorders, vol. 8, no. 5, pp. 869-881.e2.
Miller, AJ, Schubart, JR, Sheehan, T, Bascom, R & Francomano, CA 2020, 'Arterial elasticity in ehlers-danlos syndromes', Genes, vol. 11, no. 1, 55.
Stokes, WA, Schubart, J & Carr, MM 2020, 'Response to a Letter on Postoperative Bleeding Associated with Ibuprofen Use After Tonsillectomy', Otolaryngology - Head and Neck Surgery (United States), vol. 162, no. 2, pp. 265-266.


Schubart, JR, Levi, B, Bain, MM, Farace, E & Green, M 2019, 'Advance care planning among patients with advanced cancer', Journal of oncology practice, vol. 15, no. 1, pp. E65-E73.
O'Brien, DC, Desai, Y, Schubart, J, Swanson, RT, Chung, S, Parekh, U & Carr, MM 2019, 'Effect of intra-op morphine on children with OSA undergoing tonsillectomy', International Journal of Pediatric Otorhinolaryngology, vol. 125, pp. 141-146.
Bascom, R, Schubart, JR, Mills, S, Smith, T, Zukley, LM, Francomano, CA & McDonnell, N 2019, 'Heritable disorders of connective tissue: Description of a data repository and initial cohort characterization', American Journal of Medical Genetics, Part A, vol. 179, no. 4, pp. 552-560.
Carr, MM, Schaefer, EW & Schubart, JR 2021, 'Post-Tonsillectomy Outcomes in Children With and Without Narcotics Prescriptions', Ear, Nose and Throat Journal, vol. 100, no. 2, pp. 124-129.
Stokes, W, Swanson, RT, Schubart, J & Carr, MM 2019, 'Postoperative Bleeding Associated with Ibuprofen Use after Tonsillectomy: A Meta-analysis', Otolaryngology - Head and Neck Surgery (United States), vol. 161, no. 5, pp. 734-741.
Schubart, JR, Schaefer, E, Janicki, P, Adhikary, S, Schilling, AL, Hakim, AJ, Bascom, R, Francomano, C & Raj, SR 2019, 'Resistance to Local Anesthesia in People with the Ehlers-Danlos Syndromes Presenting for Dental Surgery', Journal of Dental Anesthesia and Pain Medicine, vol. 19, no. 5, pp. 261-270. <>
Schubart, JR, Schaefer, E, Hakim, AJ, Francomano, CA & Bascom, R 2019, 'Use of Cluster Analysis to Delineate Symptom Profiles in an Ehlers-Danlos Syndrome Patient Population', Journal of Pain and Symptom Management, vol. 58, no. 3, pp. 427-436.
Schubart, JR, Schilling, A, Schaefer, E, Bascom, R & Francomano, C 2019, 'Use of prescription opioid and other drugs among a cohort of persons with Ehlers–Danlos syndrome: A retrospective study', American Journal of Medical Genetics, Part A, vol. 179, no. 3, pp. 397-403.